Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\AO-YL using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\AO-YL in JBrowseY-
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Progeny survival from abo mothers depends in part upon the maternal dosage of ABO-X heterochromatin: recovery of daughters decreased if the mother was ABO-X-/ABO-X- and increased if they received an ABO-X- X chromosome from a heterozygote mother. These results suggest an interactive effect between the ABO-X deficient X and the ABO-X heterochromatin in the maternal genome. The ABO-X heterochromatin on the X chromosome rescues zygotes from the abo maternal effect prior to the completion of the first zygotic division.
Maintained homozygous abo stocks show a decrease in maternally-induced embryonic lethality over time. The altered genetic factors responsible are abo-responsive heterochromatic rescuing regions that act zygotically, dominantly and additively to reduce lethality. The regions map to the second and X chromosome in the maintained homozygous abo stock.
One of a series of heterochromatic elements capable of reducing the level of maternally influenced preblastoderm, but not postblastoderm, mortality among the progeny of abo/abo mothers; embryos that carry ABO-X elements survive better than those that do not (FBrf0042656). The rescuing capability of ABO-X approximates that of ABO-YL + ABO-YS.
Source for identity of: AO-YL ABO-YL
"AO" was substituted for the gene symbol prefix "ABO", since that is highly offensive when used to refer to the Aborigine, the native people of Australia.
