Su(z)5, M(2)21AB, SamS, SAM synthase, Minute (2) 21AB
Variable use of small exons; supported combination results in frameshift and premature stop in downstream exon.
Gene model reviewed during 5.44
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa.
2.0 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sam-S using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sam-S in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: M(2)21AB CG2674
FlyBase Curator comment: Renamed from 'M(2)21AB' to 'Sam-S' because this gene has not been validated as a typical Minute gene, and because 'Sam-S' was the first meaningful symbol to be used for this gene in a published paper.
Not a Minute locus.
Expression is enriched in embryonic gonads.
Mutant M(2)21AB is caused by changes in the gene encoding the enzyme S-adenosylmethionine synthetase. Dominant suppressor and enhancer effects are likely to be caused by a decrease in spermine concentration and it is also likely that polyamines are important molecules in the assembly of higher order chromatin structure.
Isolated from a Drosophila pupal cDNA library.
One of a class of genes (see MIN record) that when present in one, rather than two, copies, produce a characteristic phenotype consisting of short slender bristles and delayed development.