l(1)BP4, l(1)10Aa, csk
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\costakink using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\costakink in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: costakink csk
The gene symbol "csk" has been changed to "costakink" in order to reduce confusion with the "Csk" ("C-terminal Src kinase") gene symbol, from which it differed only by case.
Most alleles are lethal; originally described on basis of a single surviving semi-lethal allele which displayed smaller eyes, with wings slightly reduced in size and abnormally held, with the costal vein frequently kinked near L2. Not fully penetrant; male viability and fertility good; female fertility reduced to about 50% wild type. Survivors of other semi-lethal or nearly lethal alleles display similar phenotype (Zhimulev, Pokholkova, Bgatov, Umbetova, Solovjeva, Khudyakov and Belyaeva, 1987). Lethal allele csk33, functions in homozygous germ-line clones, but has no maternal effect (Perrimon, Engstrom and Mahowald, 1989). Fate maps, as a bilateral domineering mutant, to a broad region of the neurogenic ectoderm posterior to the metathoracic ganglion; in addition a nonautonomous focus in the wing disc gives rise to crumpled turned up wings (Bgatov, Zharkikh and Zhimulev, 1984).