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Gene Dmel\Mbs

General Information
Symbol	Dmel\Mbs	Species	D. melanogaster
Name	Myosin binding subunit	Annotation symbol	CG32156
Feature type	protein_coding_gene	FlyBase ID	FBgn0005536
Gene Model Status	Current	Stock availability	13 publicly available
Also Known As	l(3)72Dd, DMBS, DMYPT
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	72D1-72D1	Sequence location	3L:16,045,068..16,075,126 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Myosin binding subunit is referred to in FlyBase by the symbol Dmel\Mbs (CG32156, FBgn0005536). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: myosin phosphatase activity. There is experimental evidence that it is involved in the biological process: dorsal closure; regulation of compound eye photoreceptor development; axon extension involved in development; oogenesis; epidermis development; germline ring canal formation; imaginal disc-derived wing hair organization. 41 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; ring canal; embryonic/first instar larval cuticle; eye; adult abdomen; dorsal hair; wing; embryonic/larval epidermis; embryonic leading edge cell. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult crop, adult heart. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, inseminated spermatheca, adult male accessory gland, larval/adult carcass. Gene sequence location is 3L:16045068..16075126.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	Sequence features HFA10553 BKN60545 BKN60654 BKN29231 HFA10525 HFA09414
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 72D1-72D1   Limits computationally determined from genome sequence between P{lacW}thj5C8&P{PZ}Mbs03802 and P{lacW}SsRβs1939
Experimentally Determined Cytological Location
Cytogenetic map Notes References 72D1-72D2   (determined by in situ hybridisation)   (Spradling et al., 1999) 72C-72C   (determined by in situ hybridisation)   (Szeged Stock Center, 1998-) 72C-72C   (determined by in situ hybridisation)   (Deak et al., 1997) 72D1-72D2   (determined by in situ hybridisation)   (Perrimon et al., 1996) 72D1-72D2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Mbs for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Mbs-RE FBtr0075441  NM_140573   1905   377 Mbs-RF FBtr0112850  NM_001104143   2403   367 Mbs-RG FBtr0112851  NM_001104144   4047   795 Mbs-RH FBtr0112852  NM_001104145   4433   925 Mbs-RI FBtr0301472  NM_168646   5093   1144 Mbs-RJ FBtr0301473  NM_168648   4946   1101 Mbs-RK FBtr0301575  NM_168647   4242   860 Mbs-RL FBtr0308212     4671   1230 Mbs-RM FBtr0308213     5415   1243 Mbs-RN FBtr0308214     5674   1245 Mbs-RO FBtr0308215     5486   1273 Mbs-RP FBtr0308216     4873   341
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Mbs-PE   FBpp0075199   40.3   377   10.55     NP_648830   AAF49546 Mbs-PF   FBpp0111763   39.3   367   10.35     NP_001097613   ABW08546 Mbs-PG   FBpp0111764   87.3   795   6.39     NP_001097614   ABW08547 Mbs-PH   FBpp0111765   101.2   925   7.05     NP_001097615   ABW08548 Mbs-PI   FBpp0290687   123.6   1144   5.54     NP_730099   AAN11758 Mbs-PJ   FBpp0290688   119.2   1101   5.41     NP_730101   AAN11759 Mbs-PK   FBpp0290790   93.7   860   5.16     NP_730100   AAF49547 Mbs-PL   FBpp0300532   133.0   1230   5.97       Mbs-PM   FBpp0300533   133.8   1243   6.12       Mbs-PN   FBpp0300534   134.0   1245   6.12       Mbs-PO   FBpp0300535   137.4   1273   6.13       Mbs-PP   FBpp0300536   37.8   341   5.62
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ankyrin repeat (IPR002110) Ankyrin repeat-containing domain (IPR020683)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567850   AA695122   AA697519   AE014296 AAF49546   AE014296 AAF49547   AE014296 AAN11758   AE014296 AAN11759   AE014296 ABW08546   AE014296 ABW08547   AE014296 ABW08548   AF500094 AAM74143   AI062985   AI293114   AI517049   AI543757   AQ034058   AQ073149   AW940614   AW941925   AY048675 AAL06601   AY048676 AAL06602   AY051508 AAK92932   AY060844 AAL28392   AY118409 AAM48438   BE978220   BF498291   BG635361   BG640033   BI172239   BI237897   BI374559   BI375996   BI563731   BI567215   BI587136   BI592493   BI592656   BI606301   BI609469   BI609687   BI609973   BI611002   BI611012   BI613739   BI620173   BI621325   BI623014   BI629237   BP546429   BP546905   BT125704   CK135619   CO186110   CO190011   CO263893   CO265504   CO266587   CO266984   CO267285   CO267659   CO276261   CO276973   CO282950   CO287908   CO292969   CO298600   CO298607   CO302019   CO303678   CO304943   CO306468   CO308958   CO309034   CO309892   CO310533   CO313633   CO315258   CO321787   CO322250   CO328441   CO329027   CO329566   CO334034   CO337834   CO339667   CO340937   CO341036   CO343324   CO344173   CO344282   CZ470878   CZ471071   CZ471072   CZ487818   DN154039   EC060911   EC062142   EC063074   EC065770   EC072126   EC072381   EC073201   EC073593   EC074300   EC076089   EC077512   EC082945   EC083123   EC084509   EC085784   EC089198   EC195497   EC204836   EC207540   EC213009   EC217221   EC221834   EC224702   EC225700   EC225956   EC226016   EC226017   EC226654   EC233379   EC235655   EC239917   EC241257   EC244991   EC250928   EC254927   EC255912   EC259824   EC260377   EC263427   EL883338   EL885657   EL886826   EL886884   EL887287   ES690051   EV599000   GH945754   GH946396   GH956002
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86R99 Q86RA0 Q8IQN4 Q8MT32 Q8MV37 Q95SD5 Q9VUX6 Q9VUX7 A8JNT6 A8JNT4 A8JNT5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 17   organism | ubiquitous   (Mizuno et al., 2002) Comment:early expression is maternally deposited third instar larval stage   imaginal disc | ubiquitous   (Mizuno et al., 2002)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0005536    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0005536 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0005536 expression level Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (1260) embryo 04-06hr  (1450) embryo 06-08hr  (1874) embryo 08-10hr  (1633) embryo 10-12hr  (1142) embryo 12-14hr  (1479) embryo 14-16hr  (1835) embryo 16-18hr  (1986) embryo 18-20hr  (1945) embryo 20-22hr  (1534) embryo 22-24hr  (1540) larva L1  (1073) larva L2  (883) larva L3 12hr old  (797) larva L3 puffstage 1-2  (650) larva L3 puffstage 3-6  (1517) larva L3 puffstage 7-9  (1900) white prepupae new  (1732) white prepupae 12hr  (1904) white prepupae 24hr  (1746) pupae 2d postWPP  (2603) pupae 3d postWPP  (2613) pupae 4d postWPP  (2201) adult male 01day  (2099) adult male 05day  (2092) adult male 30day  (1800) adult female 01day  (1954) adult female 05day  (2010) adult female 30day  (2110) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr    1260 embryo 04-06hr  1450 embryo 06-08hr  (1874) embryo 08-10hr  (1633) embryo 10-12hr    1142 embryo 12-14hr  1479 embryo 14-16hr  (1835) embryo 16-18hr  (1986) embryo 18-20hr  (1945) embryo 20-22hr  (1534) embryo 22-24hr  (1540) larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6  (1517) larva L3 puffstage 7-9  (1900) white prepupae new  (1732) white prepupae 12hr  (1904) white prepupae 24hr  (1746) pupae 2d postWPP  (2603) pupae 3d postWPP  (2613) pupae 4d postWPP  (2201) adult male 01day  (2099) adult male 05day  (2092) adult male 30day  (1800) adult female 01day  (1954) adult female 05day  (2010) adult female 30day  (2110) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0005536 expression level Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (1260) embryo 04-06hr  (1450) embryo 06-08hr  (1874) embryo 08-10hr  (1633) embryo 10-12hr  (1142) embryo 12-14hr  (1479) embryo 14-16hr  (1835) embryo 16-18hr  (1986) embryo 18-20hr  (1945) embryo 20-22hr  (1534) embryo 22-24hr  (1540) larva L1  (1073) larva L2  (883) larva L3 12hr old  (797) larva L3 puffstage 1-2  (650) larva L3 puffstage 3-6  (1517) larva L3 puffstage 7-9  (1900) white prepupae new  (1732) white prepupae 12hr  (1904) white prepupae 24hr  (1746) pupae 2d postWPP  (2603) pupae 3d postWPP  (2613) pupae 4d postWPP  (2201) adult male 01day  (2099) adult male 05day  (2092) adult male 30day  (1800) adult female 01day  (1954) adult female 05day  (2010) adult female 30day  (2110) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr    1260 embryo 04-06hr  1450 embryo 06-08hr  1874 embryo 08-10hr  1633 embryo 10-12hr    1142 embryo 12-14hr  1479 embryo 14-16hr  1835 embryo 16-18hr  1986 embryo 18-20hr  1945 embryo 20-22hr  1534 embryo 22-24hr  1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6  1517 larva L3 puffstage 7-9  1900 white prepupae new  1732 white prepupae 12hr  1904 white prepupae 24hr  1746 pupae 2d postWPP  (2603) pupae 3d postWPP  (2613) pupae 4d postWPP  2201 adult male 01day  2099 adult male 05day  2092 adult male 30day  1800 adult female 01day  1954 adult female 05day  2010 adult female 30day  2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    1260 embryo 04-06hr    1450 embryo 06-08hr    1874 embryo 08-10hr    1633 embryo 10-12hr    1142 embryo 12-14hr    1479 embryo 14-16hr    1835 embryo 16-18hr    1986 embryo 18-20hr    1945 embryo 20-22hr    1534 embryo 22-24hr    1540 larva L1    1073 larva L2    883 larva L3 12hr old    797 larva L3 puffstage 1-2    650 larva L3 puffstage 3-6    1517 larva L3 puffstage 7-9    1900 white prepupae new    1732 white prepupae 12hr    1904 white prepupae 24hr    1746 pupae 2d postWPP    2603 pupae 3d postWPP    2613 pupae 4d postWPP    2201 adult male 01day    2099 adult male 05day    2092 adult male 30day    1800 adult female 01day    1954 adult female 05day    2010 adult female 30day    2110 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0005536    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0005536 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult crop, adult heart. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland, larval trachea, inseminated spermatheca, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0005536 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32156-RE;CG32156-RC FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Mbs Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal MbsCB02150 lethal (with Df(3L)st-f13) MbsS005331 MbsS041315a MbsS057306b lethal (with Df(3L)th102) Mbs2-188 Mbs2-199 Mbs03802 lethal | embryonic stage Mbs03802 lethal | embryonic stage (with MbsT541) MbsT666 MbsT791 lethal | embryonic stage (with MbsT666) MbsT541 lethal | embryonic stage (with MbsT791) MbsT541 lethal | embryonic stage | maternal effect, with Mbs3/Df(3L)th117, Scer\GAL4[-]: MbsEP3727 lethal | embryonic stage | maternal effect (with Df(3L)th117), with MbsEP3727, Scer\GAL4[-]: Mbs3 lethal | germline clone | maternal effect Mbs03802 lethal | larval stage (with Df(3L)th117) MbsP2r31 lethal | larval stage | recessive Mbs3 Mbs03802 MbsP2r31 MbsS005331 MbsS057306b lethal | polyphasic | recessive Mbs03802 lethal | pupal stage, with Scer\GAL4da.G32 MbsN300.Scer\UAS lethal | pupal stage | recessive MbsP2r31 MbsS005331 lethal | recessive Mbs2-188 Mbs2-199 Mbs7-51 Mbs03802 Mbsj3B4 Mbsj7A1 MbsS041315a MbsS057306b MbsS095304 viable, with Scer\GAL4[-]: MbsEP3727 Sterility Allele female sterile Mbs03802 fertile, with Mbs03802 Mbshs.PT fertile, with Mbshs.PT Mbs03802 Other Phenotypes Allele axis specification defective | embryonic stage 15, with Scer\GAL4how-24B MbsN300.Scer\UAS axis specification defective | embryonic stage 16, with Scer\GAL4how-24B MbsN300.Scer\UAS axis specification defective | embryonic stage 17, with Scer\GAL4how-24B MbsN300.Scer\UAS neuroanatomy defective | somatic clone | third instar larval stage MbsH2568 visible, with Scer\GAL4[-]: MbsEP3727 visible, with Scer\GAL4GMR.PF MbsGS13173 Phenotype manifest in Allele adult abdomen, with Scer\GAL4NP0056 MbsN300.Scer\UAS anterior embryonic/larval midgut | embryonic stage 15, with Scer\GAL4how-24B MbsN300.Scer\UAS anterior embryonic/larval midgut | embryonic stage 16, with Scer\GAL4how-24B MbsN300.Scer\UAS anterior embryonic/larval midgut | embryonic stage 17, with Scer\GAL4how-24B MbsN300.Scer\UAS axon | somatic clone | third instar larval stage MbsH2568 centriole | germline clone Mbs03802 dorsal hair, with Mbs3/Df(3L)th117, Scer\GAL4[-]: MbsEP3727 dorsal hair, with MbsEP3727/Df(3L)th117, Scer\GAL4[-]: Mbs3 dorsal hair (with Df(3L)th117), with Mbs3, Scer\GAL4[-]: MbsEP3727 dorsal hair (with Df(3L)th117), with MbsEP3727, Scer\GAL4[-]: Mbs3 egg | germline clone Mbs03802 embryonic/first instar larval cuticle Mbs03802 Mbs7-51 embryonic/first instar larval cuticle (with Df(3L)th102) Mbs03802 embryonic/first instar larval cuticle | dorsal, with Mbs3/Df(3L)th117, Scer\GAL4[-]: MbsEP3727 embryonic/first instar larval cuticle | dorsal, with MbsEP3727/Df(3L)th117, Scer\GAL4[-]: Mbs3 embryonic/first instar larval cuticle | dorsal (with Df(3L)th117), with Mbs3, Scer\GAL4[-]: MbsEP3727 embryonic/first instar larval cuticle | dorsal (with Df(3L)th117), with MbsEP3727, Scer\GAL4[-]: Mbs3 embryonic/larval epidermis, with Scer\GAL4NP0056 MbsN300.Scer\UAS embryonic leading edge cell Mbs03802 Mbs2-199 embryonic leading edge cell, with Mbs3/Df(3L)th117, Scer\GAL4[-]: MbsEP3727 embryonic leading edge cell, with MbsEP3727/Df(3L)th117, Scer\GAL4[-]: Mbs3 embryonic leading edge cell (with Df(3L)th117), with Mbs3, Scer\GAL4[-]: MbsEP3727 embryonic leading edge cell (with Df(3L)th117), with MbsEP3727, Scer\GAL4[-]: Mbs3 embryonic proventriculus | embryonic stage 15, with Scer\GAL4how-24B MbsN300.Scer\UAS embryonic proventriculus | embryonic stage 16, with Scer\GAL4how-24B MbsN300.Scer\UAS embryonic proventriculus | embryonic stage 17, with Scer\GAL4how-24B MbsN300.Scer\UAS eye, with Scer\GAL4GMR.PF MbsGS13173 eye disc | somatic clone MbsT541 MbsT666 MbsT791 germline cyst Mbs2-199 morphogenetic furrow | somatic clone MbsT791 nurse cell | germline clone Mbs03802 nurse cell ring canal | germline clone Mbs03802 ovariole | germline clone Mbs03802 ring canal Mbs03802 Mbs2-199 ring canal, with Mbs03802 Mbshs.PT ring canal, with Mbshs.PT Mbs03802 ring canal (with Mbs03802) MbsT541 MbsT666 ring canal (with MbsT541) Mbs03802 ring canal (with MbsT666) Mbs03802 ring canal | germline clone Mbs03802 wing, with Scer\GAL4[-]: MbsEP3727 wing hair | somatic clone MbsT666
Classical Alleles ( 32 )
For All Classical Alleles Show
Allele of Mbs Class Mutagen Stocks Known lesion Mbs3 ethyl methanesulfonate 2 -- Mbs03802 hypomorphic allele - genetic evidence P-element activity 1 -- Mbsc06909 piggyBac transposase 1 -- MbsEP3727 P-element activity 1 -- Mbsf05193 piggyBac transposase 1 -- MbsGS13173 1 Yes MbsGS3057 1 -- MbsNP0011 1 -- MbsNP0012 1 -- MbsNP4493 1 -- Mbs1 ethyl methanesulfonate 0 -- Mbs2-188 Delta2-3 0 -- Mbs2-199 Delta2-3 0 -- Mbs2 ethyl methanesulfonate 0 -- Mbs4 ethyl methanesulfonate 0 -- Mbs5 ethyl methanesulfonate 0 -- Mbs6 ethyl methanesulfonate 0 -- Mbs7-51 Delta2-3 0 -- Mbsc06635 piggyBac transposase 0 -- MbsCB02150 P-element activity 0 Yes MbsH2568 ethyl methanesulfonate 0 -- Mbsj3B4 P-element activity 0 -- Mbsj7A1 P-element activity 0 -- MbsP2r31 P-element activity 0 Yes MbsS005331 Delta2-3 P-element activity 0 -- MbsS041315a Delta2-3 P-element activity 0 -- MbsS057306b Delta2-3 P-element activity 0 -- MbsS095304 Delta2-3 P-element activity 0 -- MbsT111 ethyl methanesulfonate 0 -- MbsT541 loss of function allele ethyl methanesulfonate 0 Yes MbsT666 loss of function allele ethyl methanesulfonate 0 Yes MbsT791 loss of function allele ethyl methanesulfonate 0 Yes
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Mbs Class Mutagen Stocks Known lesion MbsHMS00521 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes MbsKK109231 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes MbsdsRNA.cHa in vitro construct - RNAi 0 -- MbsGD4759 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Mbshs.PT in vitro construct - regulatory fusion 0 Yes MbsL.hs in vitro construct - regulatory fusion 0 Yes MbsN300.Scer\UAS in vitro construct - regulatory fusion 0 Yes MbsS.hs in vitro construct - regulatory fusion 0 Yes MbsScer\UAS.cLa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)BSC443 (Christensen et al., 2008.4.15, Cooper and Kennison, 2011) Df(3L)BSC774 (Christensen et al., 2009.5.6, Cooper and Kennison, 2011) Df(3L)Exel6127 (Ryder, 2004.4.26, Cooper and Kennison, 2011) Df(3L)st-e4 (BDGP Project Members, 1994-1999, Kennison, 1995.6.21, Cooper and Kennison, 2011) Df(3L)st-f13 (Szeged Stock Center, 1998-, Spradling et al., 1999, BDGP Project Members, 1994-1999, Deak et al., 1997, Cooper and Kennison, 2011) Df(3L)st-g24 (Cooper and Kennison, 2011) Df(3L)th102 (Tan et al., 2003, BDGP Project Members, 1994-1999, Kennison, 1995.6.21, Cooper and Kennison, 2011) Df(3L)th117 (Mizuno et al., 2002, BDGP Project Members, 1994-1999, Kennison, 1995.6.21, Cooper and Kennison, 2011)
Not disrupted in	Df(3L)brm11 (Szeged Stock Center, 1998-, BDGP Project Members, 1994-1999, Kennison, 1995.6.21) Df(3L)st4 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4759} NA P{KK109231} NA P{TRiP.HMS00521} NA P{UAS-Mbs.L} NA P{UAS-Mbs.N300} NA heat-shock construct P{hs-Mba.T} NA P{hs-Mbs.L} NA P{hs-Mbs.S} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}MbsEP3727 NA P{GSV1}MbsGS3057 NA P{GSV6}MbsGS13173 NA insertion of enhancer trap P{lacW}Mbsj3B4 No P{lacW}Mbsj7A1 No P{lacW}MbsS041315a No P{lacW}MbsS057306b No P{lacW}MbsS095304 No P{PZ}Mbs03802 No insertion of enhancer trap binary system P{GawB}MbsNP0011 No P{GawB}MbsNP0012 No P{GawB}MbsNP4493 No miscellaneous insertions P{PTT-GB}MbsCB02150 NA PBac{PB}Mbsc06635 NA PBac{PB}Mbsc06909 NA PBac{WH}Mbsf05193 NA
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function
CV term Evidence References
myosin phosphatase activity inferred from mutant phenotype (Lee and Treisman, 2004)
Biological Process
CV term Evidence References
axon extension involved in development inferred from mutant phenotype (Berger et al., 2008) dorsal closure inferred from mutant phenotype (Mizuno et al., 2002, Tan et al., 2002, Tan et al., 2003) epidermis development inferred from mutant phenotype (Ninov et al., 2007) germline ring canal formation inferred from mutant phenotype (Ong et al., 2010) imaginal disc-derived wing hair organization inferred from mutant phenotype (Lee and Treisman, 2004) oogenesis inferred from mutant phenotype (Perrimon et al., 1996) regulation of compound eye photoreceptor development inferred from mutant phenotype (Lee and Treisman, 2004)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
myosin binding inferred from sequence or structural similarity with EMBL:D37986 (FlyBase, 1992-) non-traceable author statement (Tan, 2002.4.8, Mizuno, 2001.7.27) myosin phosphatase activity inferred from sequence or structural similarity (Tan et al., 2002) inferred from sequence or structural similarity with EMBL:D37986 (FlyBase, 1992-) non-traceable author statement (Tan, 2002.4.8, Mizuno, 2001.7.27)
Biological Process
CV term Evidence References
dorsal closure non-traceable author statement (Harden, 2002)
Cellular Component
CV term Evidence References
myosin phosphatase complex inferred from sequence or structural similarity with EMBL:D37986 (FlyBase, 1992-) non-traceable author statement (Tan, 2002.4.8, Mizuno, 2001.7.27)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Mbs allele Gene References Mbs3 zip (Mizuno et al., 2002) Mbs03802 Rho1 (Tan et al., 2003) MbsEP3727 zip (Mizuno et al., 2002) MbsL.hs flw (Vereshchagina et al., 2004) MbsN300.Scer\UAS rok (Lee and Treisman, 2004) MbsT541 dsh (Lee and Treisman, 2004) sqh (Lee and Treisman, 2004) zip (Lee and Treisman, 2004) unspecified pbl (Gregory et al., 2007)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 71956 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0005536 DroID - A comprehensive database of gene and protein interactions. • FBgn0005536 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 49070
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23761 Dere\GG15946 Dgri\GH16060 Dmoj\GI12323 Dpse\GA16721 Dsec\GM25580 Dsim\GD14592 Dvir\GJ13261 Dwil\GK24127 Dyak\GE22289
Curated drosophilid orthologs	Dpse\GA16721
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18624 NV18107 LH22983 ISCW021906 FBgn0239514 FBgn0226089 FBgn0219143 FBgn0200487 FBgn0186272 FBgn0180437 JGI_V11_234539 FBgn0076736 FBgn0162671 FBgn0135080 FBgn0123531 FBgn0108181 FBgn0100755 CPIJ006926 BGIBMGA002008 ACYPI007693 GB19581 AGAP006665 AAEL012753 PHUM561400 GLEAN_03209
Stocks & Reagents
Stocks Listed in FlyBase ( 13 )
Bloomington	5054 Mbs3/TM2 17279 w1118; P{EP}MbsEP3727 32516 y1 sc* v1; P{TRiP.HMS00521}attP2 11607 P{PZ}Mbs03802 ry506/TM3, ryRK Sb1 Ser1
Harvard	- PBac{PB}Mbsc06909 - PBac{WH}Mbsf05193
Kyoto	108012 Mbs3/TM2 112006 w*; P{GawB}MbsNP0011 / TM6, P{UAS-lacZ.UW23-1}UW23-1 103494 y* w*; P{GawB}MbsNP0012 / TM6, P{UAS-lacZ.UW23-1}UW23-1 104697 y* w*; P{GawB}MbsNP4493 / TM6, P{UAS-lacZ.UW23-1}UW23-1 200447 y1 w67c23; P{GSV1}MbsGS3057/TM3, Sb1 Ser1
VDRC	v105762 P{KK109231}VIE-260B
	More stocks available...
Genomic Clones ( 2 )
	BACR18K24 BACR25O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 119 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH16214 GM02173 RE63915
Other clones	DPiM_GH16214 MIP27266
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT12677 AT31926 GH02381 GH27673 HL01886 HL02706 RE14551 RE34228 RE62183 RH10195 RH10409 RH14254 RH14507 RH14833 RH17069 RH17086 RH27610 RH34431 RH37084 RH42961 RH51247 RH52649 RH55070 RH72603
Other clones	1438 14144 30038 30256 33155 34217 35889 36967 38702 45656 45784 59324 59796 62400 72792 79563 79748 99584 107653 119647 120577 124128 148371 156802 157067 190756 211016 214317.55 214377.21 214405.68 214471.52 283011 569682 bs75e11 CK01.16A.A12 CK01.55D.E9 CK01.57D.F12 CK01.84C.H11 CK01.147A.G4 Dmel_neb_014216_0926_2691 EK015936 EK045956 EK067124 EK120158 EK122536 EK136809 EK142824 EK146952 EK148063 EK149334 EK151446 EK161833 EK161835 EK173333 EK173341 EK182907 EK186362 EK187722 EK201332 EK219706 EK221941 EK233618 EK239802 EK242352 EK246758 EK251130 EK259764 EK259946 EK291864 EK293125 EK308713 EN15363 EP02502 EP09218 EP11611 EP11751 EP16563 EP18803 EP19002 FGH106C11 FGH111D03 IP13027 IP17017 IP18052 IP18423 RH58075 RP004087522 RP004220250 RP004227119 SD10650
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0005536 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 46932 46971 49070
Antibody Information
	polyclonal (Ong et al., 2010, Mizuno et al., 2002)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Mbs l(3)72Dd (Mizuno et al., 2002)
Source for database merge of	Source for merge of: l(3)S057306b l(3)S005331b (Szeged Stock Center, 1998-) Source for merge of: l(3)S095304 Mbs l(3)S057306b (Lee and Treisman, 2004) Source for merge of: Mbs CG5891 (FlyBase, 1996-)
Additional comments	Annotations CG5600, CG5891 merged as CG32156 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of Mbs CG5891 was sequence comparison (date:020814). (FlyBase, 1996-)
Other Comments
	The 'l(3)72Dd' (Mbs) complementation group comprises 11 EMS-induced mutant alleles. (Cooper and Kennison, 2011) Mbs is enriched in cells undergoing incomplete cytokinesis. (Ong et al., 2010) Photoreceptor neurons require Mbs to reduce myosin activity and thus prevent photoreceptors from dropping out of the eye disc epithelium and moving toward and through the optic stalk. Mbs reduces myosin activity by dephosphorylating sqh. (Lee and Treisman, 2004) Mutations in Mbs cause embryos to develop a dorsal-open phenotype. (Tan et al., 2002) The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. Mbs is required for germ cell viability or early oogenesis. (Perrimon et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_140573 NM_168646 NM_168647 NM_168648 NM_001104143 NM_001104144 NM_001104145 RefSeq (Proteins) • NP_648830 NP_730099 NP_730100 NP_730101 NP_001097613 NP_001097614 NP_001097615 DDBJ / EMBL / GenBank • AA695122 AAF49546 AAF49547 AAK92932 AAL06601 AAL06602 AAL28392 AAM48438 AAM74143 AAN11758 AAN11759 ABW08546 ABW08547 ABW08548 AF500094 AI293114 AI517049 AQ034058 AQ073149 AW940614 AW941925 AY048675 AY048676 AY051508 AY060844 AY118409 BI375996 CZ470878 CZ471071 CZ471072 CZ487818 Entrez Gene - A searchable database of RefSeq genes. • 49070 UniProtKB/TrEMBL • A8JNT4 A8JNT5 A8JNT6 Q8IQN4 Q8MT32 Q8MV37 Q9VUX6 Q9VUX7 Q86R99 Q86RA0 Q95SD5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ankyrin repeat (IPR002110) Ankyrin repeat-containing domain (IPR020683)
Linkouts
	BioGRID - A database of protein and genetic interactions • 71956 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0005536 DroID - A comprehensive database of gene and protein interactions. • FBgn0005536 DRSC - Results from RNAi screens. • FBgn0005536 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0005536 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32156-RE;CG32156-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0005536 FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways • 351046 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 46932 46971 49070 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /cytoskel/myobsub1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 49070 modMine - Data generated by the modENCODE project. • FBgn0005536 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18624 NV18107 LH22983 ISCW021906 FBgn0239514 FBgn0226089 FBgn0219143 FBgn0200487 FBgn0186272 FBgn0180437 JGI_V11_234539 FBgn0076736 FBgn0162671 FBgn0135080 FBgn0123531 FBgn0108181 FBgn0100755 CPIJ006926 BGIBMGA002008 ACYPI007693 GB19581 AGAP006665 AAEL012753 PHUM561400 GLEAN_03209
Synonyms & Secondary IDs ( 29 )
Reported As
Symbol Synonym	0573/06 (Deak et al., 1997) 0953/04 (Deak et al., 1997) CG5600 (Montana and Littleton, 2006) CG5891 (Stathopoulos et al., 2002, ) CG32156 (Laviolette et al., 2005, Carrera et al., 2008, Keleman et al., 2009.8.5, Fujikawa et al., 2009, Berger et al., 2008, Ni et al., 2010.12.1) DMBS (Vereshchagina et al., 2004, Jacinto et al., 2002, Mizuno et al., 2002, Song et al., 2007) DMbs (Todi et al., 2005) DMYPT (Balasubramanian et al., 2004, Tan et al., 2003, Tan et al., 2002, Ong and Tan, 2008, Ong et al., 2010) l(3)72Dd (Lee and Treisman, 2004, Spradling et al., 1999, Kennison, 1995.6.21, BDGP Project Members, 1994-1999, Song et al., 2007, Cooper and Kennison, 2011) l(3)03802 (Perrimon et al., 1996, ) l(3)j3B4   l(3)j7A1   l(3)S005331b   l(3)S057306   l(3)S057306b   l(3)S095304   MBS (Piekny et al., 2005) Mbs (Laviolette et al., 2005, Hickson et al., 2006, Gregory et al., 2007, Buszczak et al., 2007, Kirchner et al., 2007, Ninov et al., 2007, Christensen et al., 2008.4.15, Muraro and Moffat, 2006, Brody, 2009.03, Franciscovich et al., 2008, Carrera et al., 2008, Widmann and Dahmann, 2009, Christensen et al., 2009.5.6, Fujikawa et al., 2009, Berger et al., 2008, Baker et al., 2007, Okumura et al., 2010, Cooper and Kennison, 2011) mbs (Corrigall et al., 2007, Widmann and Dahmann, 2009) Mypt
Name Synonym	lethal(3)72Dd   lethal (3) S057306b   lethal (3) S095304   MLC-phosphatase (Petit et al., 2002) Myosin binding subunit (Mizuno et al., 2002) myosin binding subunit (Song et al., 2007, Shalaby et al., 2009) Myosin phosphatase (Tan et al., 2002) Myosin phosphatase-binding subunit (Corrigall et al., 2007) myosin phosphatase target subunit (Ong et al., 2010)
Secondary FlyBase IDs
	FBgn0010817 FBgn0011346 FBgn0011399 FBgn0028052 FBgn0028127 FBgn0036561 FBgn0036562 FBgn0052156 FBgn0061116 FBgn0062264
References ( 68 )
Generate a list of	All references relating to this gene ( 68 )
List References by type	Research paper  ( 30 ) Supplementary material  ( 3 ) Review  ( 7 ) Personal communication to FlyBase  ( 9 ) Abstract  ( 5 ) FlyBase analysis  ( 4 ) Computer file  ( 5 ) DNA/RNA sequence record  ( 2 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 ) Book  ( 1 )
Recent research papers ( 3 )
	Cooper and Kennison, 2011, PLoS ONE 6(8): e23509 Molecular Genetic Analyses of Polytene Chromosome Region 72A-D in Drosophila melanogaster Reveal a Gene Desert in 72D. [FBrf0214748] Okumura et al., 2010, Dev. Biol. 344(2): 693--706 Left-right asymmetric morphogenesis of the anterior midgut depends on the activation of a non-muscle myosin II in Drosophila. [FBrf0211383] Ong et al., 2010, Dev. Biol. 346(2): 161--169 Mutations of DMYPT cause over constriction of contractile rings and ring canals during Drosophila germline cyst formation. [FBrf0211890] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...