l(3)72Dd, DMBS, DMYPT, l(3)03802
regulatory subunit of myosin phosphatase flapwing - involved in dorsal closure - involved in cell movement and in the arrest of constriction of contractile rings and ring canals during oogenesis.
Please see the GBrowse view of Dmel\Mbs or the JBrowse view of Dmel\Mbs for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Gene model includes transcripts encoding non-overlapping portions of the full CDS.
Gene model reviewed during 6.28
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mbs using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Mbs in GBrowse 2
3-44
3-44
3-38.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: Mbs l(3)72Dd
Source for merge of: l(3)S057306b l(3)S005331b
Source for merge of: l(3)S095304 Mbs l(3)S057306b
Source for merge of: Mbs CG5891
Annotations CG5600, CG5891 merged as CG32156 in release 3 of the genome annotation.
Source for merge of Mbs CG5891 was sequence comparison ( date:020814 ).
The 'l(3)72Dd' (Mbs) complementation group comprises 11 EMS-induced mutant alleles.
Mbs is enriched in cells undergoing incomplete cytokinesis.
Mutations in Mbs cause embryos to develop a dorsal-open phenotype.
The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. Mbs is required for germ cell viability or early oogenesis.
