HMG-domain protein - SOX-domain protein - under the control of the canonical pathway such that and regulate each other's transcription through a feedback loop that results in proliferation of wing hinge cells
Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sox15 using the Feature Mapper tool.
Comment: likely socket cells of external sense organs
Sox15 transcripts are abundant in prospective hinge cells in late third instar wing discs. The Sox15 domain straddles the gap domain in the wing hinge defined by the nub and tsh domains. It is complementary to the wg and rn domains.
Sox15 protein is expressed specifically in socket cells of external sensory organs in larval and adult PNS. It is present in imaginal discs of late third instar larvae. Sox15 localizes to the presumptive hinge region in wing and haltere discs, In leg discs the protein is found in discrete patches on opposite sides of the proximal leg primordium.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sox15 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.