Cry, dcy, drosocrystallin
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.51
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Crys using the Feature Mapper tool.
Cry transcripts are first detected weakly in 2 day pupae on northern blots. Signal is very strong in 3 and 4 day pupae and is again weak in young adults. In situ hybridization shows that the mRNA is restricted to cells below the lens. These are most likely the primary pigment cells and/or the cone cells. It is also expressed in the ocelli, probably in the corneagenous cells and the retinula cells.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Crys in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The biochemical properties of a 52kD protein have been characterised by purification, N-terminal sequencing and amino acid analysis. Antibody staining shows the protein is localised specifically to the electron dense layer of the laminated corneal lens of the compound eye. The protein plays a structural role and participates in the formation of the corneal lens and its alternative refractive indicies.