• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\βCop

General Information
Symbol	Dmel\βCop	Species	D. melanogaster
Name	β-coatomer protein	Annotation symbol	CG6223
Feature type	protein_coding_gene	FlyBase ID	FBgn0008635
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	β-COP, BetaCop
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	17A9-17A9	Sequence location	X:18,275,580..18,279,228 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene β-coatomer protein is referred to in FlyBase by the symbol Dmel\βCop (CG6223, FBgn0008635). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding; structural molecule activity. There is experimental evidence that it is involved in the biological process: regulation of lipid storage; cell morphogenesis; phagocytosis, engulfment. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-like helical; Armadillo-type fold; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Coatomer, beta subunit; Coatomer, beta subunit, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult ovary, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626340_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of betaCop. Gene sequence location is X:18275580..18279228.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References D'Ambrosio and Vale, 2010, J. Cell Biol. 191(3): 471--478 Sequence features BKN22043 HFA20312 Controlled Vocabulary Terms cell morphogenesis
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 17A9-17A9   Limits computationally determined from genome sequence between P{EP}EP1378 and P{EP}CG32549EP1317
Experimentally Determined Cytological Location
Cytogenetic map Notes References 17A9-17A10     (Ripoche, 1994.4.14) 17A9-17A10   (determined by in situ hybridisation)   (Ripoche et al., 1994)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\βCop for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) betaCop-RA FBtr0074576  NM_078676   3158   964
Additional Transcript Data & Comments
Reported size (kB)	3.5 (northern blot) (Ripoche et al., 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein betaCop-PA   FBpp0074348   107.4   964   6.25     NP_523400   AAF48830
Additional Polypeptide Data & Comments
Reported size (kDa)	972 (aa); 108 (kD predicted) (Ripoche et al., 1994)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Clathrin/coatomer adaptor, adaptin-like, N-terminal (IPR002553) Coatomer, beta subunit, C-terminal (IPR011710) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024) Coatomer, beta subunit (IPR016460)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA391690   AA950593   AE014298 AAF48830   AF145656 AAD38631   AI109920   AI238468   AI293648   AI294143   AI294546   AI387278   AI387860   AI389827   AI402169   AI403220   AI403226   AI511741   AI531590   AI532061   AI532264   AI532884   AI533534   AI533869   AI534130   AI534309   AI534678   AI546707   BF489814   BF490536   BF495934   BF502940   BG636404   BI169210   BI169437   BI170283   BI171777   BI235007   BI236536   BI237928   BI241555   BI243301   BI358749   BI564417   BI568797   BI572889   BI572912   BI585357   BI589503   BI589536   BI593628   BI593682   BI616011   BI616012   BI616060   BI616078   BI616101   BI620115   BI620121   BI624095   BI632068   BI632092   BI632099   BI636148   BI638389   BI642022   BI642034   BI642039   CK135678   CK604968   CK604969   CK657448   CK660819   CO187857   CO263699   CO264111   CO276545   CO279479   CO279674   CO279933   CO280352   EC059509   EC060721   EC082414   EC084767   EC198401   EC203257   EC209648   EC209661   EC232172   EC241029   EC257599   EV596381   GH756933   GH757127   GH759442   GH759511   GH759882   GH761153   GH778737   GH779050   GH786118   GH789164   GH791106   GH793600   GH794769   GH811103   GH821298   GH821987   GH826036   GH827134   GH829354   GH835624   GH844216   GH846039   GH846336   GH849356   GH861757   GH871892   GH888134   GH902056   GH904217   GH910541   GH912117   GH915137   GH942624   L31852 AAA21090
UniProtKB/Swiss-Prot	P45437
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage | early     (Ripoche et al., 1994)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage 4 -- 5   embryonic cortex   • cis-Golgi network membrane (Lecuit and Wieschaus, 2000)
Additional Descriptive Data
	βCop protein is Golgi-membrane associated. (Ripoche et al., 1994)
Marker for
	cis-Golgi network membrane
Subcellular Localization
CV Term	Golgi apparatus (Ripoche et al., 1994)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0008635    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0008635 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0008635 expression level Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr    10404 embryo 08-10hr    10412 embryo 10-12hr    13296 embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6075) embryo 02-04hr  (2586) embryo 04-06hr  (5661) embryo 06-08hr  (10404) embryo 08-10hr  (10412) embryo 10-12hr  (13296) embryo 12-14hr  (7274) embryo 14-16hr  (8708) embryo 16-18hr  (6165) embryo 18-20hr  (5060) embryo 20-22hr  (3666) embryo 22-24hr  (2938) larva L1  (6240) larva L2  (8274) larva L3 12hr old  (6124) larva L3 puffstage 1-2  (4267) larva L3 puffstage 3-6  (5137) larva L3 puffstage 7-9  (4701) white prepupae new  (5229) white prepupae 12hr  (3662) white prepupae 24hr  (5293) pupae 2d postWPP  (4160) pupae 3d postWPP  (2495) pupae 4d postWPP  (3004) adult male 01day  (4550) adult male 05day  (4829) adult male 30day  (5397) adult female 01day  (5729) adult female 05day  (5348) adult female 30day  (5484) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6075) embryo 02-04hr  (2586) embryo 04-06hr  (5661) embryo 06-08hr  (10404) embryo 08-10hr  (10412) embryo 10-12hr  (13296) embryo 12-14hr  (7274) embryo 14-16hr  (8708) embryo 16-18hr  (6165) embryo 18-20hr  (5060) embryo 20-22hr  (3666) embryo 22-24hr  (2938) larva L1  (6240) larva L2  (8274) larva L3 12hr old  (6124) larva L3 puffstage 1-2  (4267) larva L3 puffstage 3-6  (5137) larva L3 puffstage 7-9  (4701) white prepupae new  (5229) white prepupae 12hr  (3662) white prepupae 24hr  (5293) pupae 2d postWPP  (4160) pupae 3d postWPP  (2495) pupae 4d postWPP  (3004) adult male 01day  (4550) adult male 05day  (4829) adult male 30day  (5397) adult female 01day  (5729) adult female 05day  (5348) adult female 30day  (5484) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr  10404 embryo 08-10hr  10412 embryo 10-12hr  (13296) embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr    10404 embryo 08-10hr    10412 embryo 10-12hr    13296 embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0008635 expression level Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr    10404 embryo 08-10hr    10412 embryo 10-12hr    13296 embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6075) embryo 02-04hr  (2586) embryo 04-06hr  (5661) embryo 06-08hr  (10404) embryo 08-10hr  (10412) embryo 10-12hr  (13296) embryo 12-14hr  (7274) embryo 14-16hr  (8708) embryo 16-18hr  (6165) embryo 18-20hr  (5060) embryo 20-22hr  (3666) embryo 22-24hr  (2938) larva L1  (6240) larva L2  (8274) larva L3 12hr old  (6124) larva L3 puffstage 1-2  (4267) larva L3 puffstage 3-6  (5137) larva L3 puffstage 7-9  (4701) white prepupae new  (5229) white prepupae 12hr  (3662) white prepupae 24hr  (5293) pupae 2d postWPP  (4160) pupae 3d postWPP  (2495) pupae 4d postWPP  (3004) adult male 01day  (4550) adult male 05day  (4829) adult male 30day  (5397) adult female 01day  (5729) adult female 05day  (5348) adult female 30day  (5484) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6075) embryo 02-04hr  (2586) embryo 04-06hr  (5661) embryo 06-08hr  (10404) embryo 08-10hr  (10412) embryo 10-12hr  (13296) embryo 12-14hr  (7274) embryo 14-16hr  (8708) embryo 16-18hr  (6165) embryo 18-20hr  (5060) embryo 20-22hr  (3666) embryo 22-24hr  (2938) larva L1  (6240) larva L2  (8274) larva L3 12hr old  (6124) larva L3 puffstage 1-2  (4267) larva L3 puffstage 3-6  (5137) larva L3 puffstage 7-9  (4701) white prepupae new  (5229) white prepupae 12hr  (3662) white prepupae 24hr  (5293) pupae 2d postWPP  (4160) pupae 3d postWPP  (2495) pupae 4d postWPP  (3004) adult male 01day  (4550) adult male 05day  (4829) adult male 30day  (5397) adult female 01day  (5729) adult female 05day  (5348) adult female 30day  (5484) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr  10404 embryo 08-10hr  10412 embryo 10-12hr  13296 embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6075 embryo 02-04hr    2586 embryo 04-06hr    5661 embryo 06-08hr    10404 embryo 08-10hr    10412 embryo 10-12hr    13296 embryo 12-14hr    7274 embryo 14-16hr    8708 embryo 16-18hr    6165 embryo 18-20hr    5060 embryo 20-22hr    3666 embryo 22-24hr    2938 larva L1    6240 larva L2    8274 larva L3 12hr old    6124 larva L3 puffstage 1-2    4267 larva L3 puffstage 3-6    5137 larva L3 puffstage 7-9    4701 white prepupae new    5229 white prepupae 12hr    3662 white prepupae 24hr    5293 pupae 2d postWPP    4160 pupae 3d postWPP    2495 pupae 4d postWPP    3004 adult male 01day    4550 adult male 05day    4829 adult male 30day    5397 adult female 01day    5729 adult female 05day    5348 adult female 30day    5484 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0008635    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0008635 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult spermathecae, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult ovary, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0008635 expression level Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland    2760.7 Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland    2516.4 Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland    1857.2 Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland  (2760.7) Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland  (2516.4) Adult Heart    242.025 Adult VirginFemale Spermatheca  (544.8) Adult InseminatedFemale Spermatheca  (648.3) Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland  (1857.2) Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland  (2760.7) Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland  (2516.4) Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland  (1857.2) Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland    2760.7 Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland    2516.4 Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland    1857.2 Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0008635 expression level Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland    2760.7 Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland    2516.4 Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland    1857.2 Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland  (2760.7) Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland  (2516.4) Adult Heart    242.025 Adult VirginFemale Spermatheca  544.8 Adult InseminatedFemale Spermatheca  648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland  (1857.2) Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland  (2760.7) Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland  (2516.4) Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland  (1857.2) Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    388.375 Larval Midgut    450.1 Larval Hindgut    496.6 Larval Malpighian Tubules    469.5 Larval Fat Body    466.7 Larval Salivary Gland    2760.7 Larval Trachea    446.075 Larval Carcass    425.675 Adult Head    289.1 Adult Eye    329.6 Adult Brain    231.8 Adult Thoracic-Abdominal Ganglion    261.5 Adult Crop    279.7 Adult Midgut    403.7 Adult Hindgut    272.5 Adult Malpighian Tubules    382.3 Adult Fat Body    390.3 Adult Salivary Gland    2516.4 Adult Heart    242.025 Adult VirginFemale Spermatheca    544.8 Adult InseminatedFemale Spermatheca    648.3 Adult Ovary    282.1 Adult Testis    100.2 Adult Male Accessory Gland    1857.2 Adult Carcass    319.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    289.1   NA  Eye    329.6   NA  Brain    231.8   388.375  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    261.5   NA  Crop    279.7   450.1  Midgut    403.7   496.6  Hindgut    272.5   469.5  Malpighian Tubules    382.3   466.7  Fat Body    390.3   2760.7  Salivary Gland    2516.4   NA  Heart    242.025   446.075  Trachea    NA   NA  VirginFemale Spermatheca    544.8   NA  InseminatedFemale Spermatheca    648.3   NA  Ovary    282.1   NA  Testis    100.2   NA  Male Accessory Gland    1857.2   425.675  Carcass    319.2 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0008635 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6223-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for βCop Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 βCopGD5005 lethal | pupal stage, with Scer\GAL4pnr-MD237 βCopGD5005 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of βCop Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of βCop Class Mutagen Stocks Known lesion βCopGD5005 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes βCopHM04016 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes βCopHMS01079 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes βCopdsRNA.118 in vitro construct - RNAi 0 Yes βCopdsRNA.221 in vitro construct - RNAi 0 Yes βCopdsRNA.929 in vitro construct - RNAi 0 Yes βCopdsRNA.cLa in vitro construct - RNAi 0 Yes βCopKK101977 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cell morphogenesis inferred from mutant phenotype (D'Ambrosio and Vale, 2010) phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006) regulation of lipid storage inferred from direct assay (Beller et al., 2008)
Cellular Component
CV term Evidence References
Golgi apparatus inferred from direct assay (Ripoche et al., 1994)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024 (FlyBase Curators et al., 2004-) structural molecule activity inferred from electronic annotation with InterPro:IPR011710 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
intracellular protein transport inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR011710, InterPro:IPR016460 (FlyBase Curators et al., 2004-) retrograde vesicle-mediated transport, Golgi to ER inferred from sequence or structural similarity with Saccharomyces SEC26 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1995.6.1)
Cellular Component
CV term Evidence References
COPI vesicle coat inferred from sequence or structural similarity with Saccharomyces SEC26 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1995.6.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions βCop allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59137 DroID - A comprehensive database of gene and protein interactions. • FBgn0008635 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32820
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22509 Dere\GG18127 Dgri\GH12352 Dmoj\GI15599 Dper\GL27037 Dpse\GA19453 Dsec\GM22820 Dsim\GD15643 Dvir\GJ15202 Dwil\GK19864 Dyak\GE15534
Curated drosophilid orthologs	Dmir\CG6223 (Thornton, 2005.12.20) Dpse\GA19453
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004546-PA Aedes aegypti (mosquito) AGAP001399-PA Anopheles gambiae (mosquito) XP_001120953.1 Apis mellifera (honey bee) XP_001949960.1 Acyrthosiphon pisum (pea aphid) At4g31480.1 Arabidopsis thaliana (wall cress) At4g31490.1 Arabidopsis thaliana (wall cress) 19102 Batrachochytrium dendrobatidis (chytrid fungus) 276943 Branchiostoma floridae (lancelet) XP_001896419.1 Brugia malayi (roundworm nematode) BGIBMGA013717-PA Bombyx mori (silk worm) ENSBTAP00000008616 Bos taurus (bovine) CAL0000129 Candida albicans (a form of yeast) CN18853 Caenorhabditis brenneri (small nematode) CBP04568 Caenorhabditis briggsae (nematode) CE21472 Caenorhabditis elegans (worm) ENSCAFP00000012410 Canis familiaris (dog) CAGL0K11088g Candida glabrata (haploid yeast) ENSCINP00000004542 Ciona intestinalis (sea squirt) JA16233 Caenorhabditis japonica (nematode) CMG048C Cyanidioschyzon merolae (red alga) cn07200 Cryptococcus neoformans (yeast-like fungus) cgd6_270 Cryptosporidium parvum (protozoan parasite) CPIJ003330 Culex pipens (mosquito) ENSCPOP00000013721 Cavia porcellus (guinea pig) 82549 Chlamidomonas reinhardtii (green alga) RP18929 Caenorhabditis remanei (nematode) ENSCSAVP00000017119 Ciona savignyi (sedentary tunicate) 184257 Capitella spl (polychaete worm) DDB0191250 Dictyostelium discoideum (amoeba) DEHA2F19272g Debaryomyces Hansenii (yeast) 313075 Daphnia pulex (daphnia) ENSDARP00000073498 Danio rerio (zebra fish) ENSECAP00000019738 Equus caballus (horse) XP_657557 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000020630 Gymnopilus aculeatus (mushroom) ENSGALP00000009665 Gallus gallus (chicken) GL50803_88082 Giardia lamblia (flagellated protozoan) 101151 Hypsipyla robusta (cedar shoot borer) ENSP00000249923 Homo sapiens (human) ISCW012850-PA Ixodes scapularis (deer tick) KLLA0C15279g Kluyveromyces lactis (yeast) 183679 Lottia gigantea (owl limpet) LmjF20.1350 Leishmania major (virus) 38413 Monocosta brevicollis (choanoflagellate) ENSMODP00000009098 Monodelphis domestica (gray opossum) ENSMMUP00000021600 Macaca mulatta (rhesus monkey) ENSMUSP00000033012 Mus musculus (house mouse) 124098 Nematostella vectensis (starlet anemone) XP_001606861.1 Nasonia vitripennis (wasp) ENSOANP00000010972 Ornithorynchus anatinus (platypus) ENSORLP00000008536 Oryzias latipes (japanese killifish) LOC_Os01g17430.1 Oryza sativa (asian rice) 23611 Ostreococcus tauri (green alga) PF14_0277 Plasmodium falciparum (protozoal parasite) PHUM001625-PA Pediculus humanus (human body louse) PP16654 Pristionchus pacificus (nematode) 162358 Physcomitrella patens (moss) ENSPPYP00000003980 Pongo pygmaeus (orangutan) 80460 Phytophthora ramorum (sudden oak death pathogen) 108280 Phytophthora sojae (root rot pathogen) 578384 Populus trichocarpa (black cottonwood) ENSPTRP00000005903 Pan troglodytes (chimpanzee) PVX_085050 Plasmodium vivax (protozoal parasite) ENSRNOP00000016292 Rattus norvegicus (norway rat) 5052979 Sorghum bicolor (sorghum) YDR238C Saccharomyces cerevisiae (budding yeast) Smp_124430 Schistosoma mansoni (trematode parasite) SPBC146.14c Schizosaccharomyces pombe (fission yeast) 22765 Trichoplax adhaerens (metazoa) TA02765 Theileria annulata (apicomplexan parasite) XP_001816488.1 Tribolium castaneum (red flour beetle) Tc00.1047053506563.30 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012248 Tetraodon nigroviridis (green spotted pufferfish) TP01_0687 Theileria parva (parasitic protozoan) 26212 Thalassiosira pseudonana (marine diatom) ENSTRUP00000044513 Takifugu rubripes (pufferfish Takifugu) 60.m00135 Tetrahymena thermophila (ciliate protozoa) 92921.m00289 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000042611 Xenopus tropicalis (frog) YALI0F19074g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14345 LH20800 ISCW012850 FBgn0233107 FBgn0221862 FBgn0202398 FBgn0187305 FBgn0177690 JGI_V11_313075 FBgn0079449 FBgn0164618 FBgn0138348 FBgn0119831 FBgn0110343 FBgn0099505 CPIJ003330 BGIBMGA013717 ACYPI005687 ACYPI000894 GB13119 AGAP001399 AAEL004546 PB20395 PHUM055740 GLEAN_00641
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	31709 y1 v1; P{TRiP.HM04016}attP2 33741 y1 sc* v1; P{TRiP.HMS01079}attP2
VDRC	v15418 w1118; P{GD5005}v15418 v15419 w1118; P{GD5005}v15419
Genomic Clones ( 2 )
	BACR03K10 BACR10E05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 119 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH09317
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT09625 AT18805 AT25975 AT27032 GH14515 GH17765 GH18535 GH21101 GH22617 GH22624 GM27780 LD11625 LD30451 LD43243 LP06832 LP07452 LP07946 LP19708 LP23755 RE10318 RE10614 RE11679 RE13625 RE30801 RE32607 RE34262 RE38654 RE40886 RH04459 RH05894 RH07083 RH10443 RH23191 RH28273 RH31643 RH35885 RH39418 RH40840 RH40880 RH43525 RH44325 RH45711 RH49313 RH49535 RH53089 RH59975 RH61236 RH61547 SD02688 SD03424 SD03695 SD04529 SD05390 SD05841 SD06646 SD07101 SD07640 SD10461 SD14111 SD17728 SD20666 SD22915 SD23913 SD24132
Other clones	541 20935 28304 28421 28880 40088 124472 214243.63 CK01.39B.B1 CK01.107A.E5 Dmel_neb_013810_0936_3008 EK034329 EK089319 EK121262 EK134631 EK135620 EK136420 EK137519 EK153836 RH47255 RP003079612 RP003100114 RP003151390 RP003168194 RP003187266 RP003231328 RP003238957 RP003245154 RP003253189 RP003254584 RP003255799 RP003272796 RP003282997 RP003305659 RP003316258 RP003329274 RP003332786 RP003336972 RP003344486 RP003374397 RP003419212 RP003468405 RP003468462 RP003504126 RP003535522 RP003541531 RP003551875 RP003581087 RP003591444 RP003621237 RP003623882 RP003671256 RP003671290 UT01577
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0008635 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32820
Antibody Information
	polyclonal (Ripoche et al., 1994)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: βCop CG6223 (Li, 1999.11)
Source for database merge of	Source for merge of: βCop BcDNA:GH09317 (FlyBase, 1996-)
Additional comments	Source for merge of βCop BcDNA:GH09317 was sequence comparison (date:990717). (FlyBase, 1996-)
Other Comments
	S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006) dsRNA made from templates generated with primers directed against βCop that is transfected into S2 treated with Listeria monocytogenes reveals βCop to be involved in Listeria monocytogenes entry and vacuolar escape. (Cheng et al., 2005) Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells. (Nybakken et al., 2005) βCop, a Golgi-associated protein, has been cloned and an antibody raised to monitor the spatial distribution of Golgi membranes with reference to the rapidly dividing nuclei in early stages of embryogenesis. (Ripoche et al., 1994)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078676 RefSeq (Proteins) • NP_523400 DDBJ / EMBL / GenBank • AAA21090 AAD38631 AAF48830 AF145656 AI109920 AI402169 L31852 Entrez Gene - A searchable database of RefSeq genes. • 32820 UniProtKB/Swiss-Prot • P45437
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Clathrin/coatomer adaptor, adaptin-like, N-terminal (IPR002553) Coatomer, beta subunit, C-terminal (IPR011710) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024) Coatomer, beta subunit (IPR016460)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59137 DroID - A comprehensive database of gene and protein interactions. • FBgn0008635 DRSC - Results from RNAi screens. • FBgn0008635 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0008635 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6223-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0008635 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32820 InParanoid A subset of ortholog calls from InParanoid. • AAEL004546-PA Aedes aegypti (mosquito) AGAP001399-PA Anopheles gambiae (mosquito) XP_001120953.1 Apis mellifera (honey bee) XP_001949960.1 Acyrthosiphon pisum (pea aphid) At4g31480.1 Arabidopsis thaliana (wall cress) At4g31490.1 Arabidopsis thaliana (wall cress) 19102 Batrachochytrium dendrobatidis (chytrid fungus) 276943 Branchiostoma floridae (lancelet) XP_001896419.1 Brugia malayi (roundworm nematode) BGIBMGA013717-PA Bombyx mori (silk worm) ENSBTAP00000008616 Bos taurus (bovine) CAL0000129 Candida albicans (a form of yeast) CN18853 Caenorhabditis brenneri (small nematode) CBP04568 Caenorhabditis briggsae (nematode) CE21472 Caenorhabditis elegans (worm) ENSCAFP00000012410 Canis familiaris (dog) CAGL0K11088g Candida glabrata (haploid yeast) ENSCINP00000004542 Ciona intestinalis (sea squirt) JA16233 Caenorhabditis japonica (nematode) CMG048C Cyanidioschyzon merolae (red alga) cn07200 Cryptococcus neoformans (yeast-like fungus) cgd6_270 Cryptosporidium parvum (protozoan parasite) CPIJ003330 Culex pipens (mosquito) ENSCPOP00000013721 Cavia porcellus (guinea pig) 82549 Chlamidomonas reinhardtii (green alga) RP18929 Caenorhabditis remanei (nematode) ENSCSAVP00000017119 Ciona savignyi (sedentary tunicate) 184257 Capitella spl (polychaete worm) DDB0191250 Dictyostelium discoideum (amoeba) DEHA2F19272g Debaryomyces Hansenii (yeast) 313075 Daphnia pulex (daphnia) ENSDARP00000073498 Danio rerio (zebra fish) ENSECAP00000019738 Equus caballus (horse) XP_657557 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000020630 Gymnopilus aculeatus (mushroom) ENSGALP00000009665 Gallus gallus (chicken) GL50803_88082 Giardia lamblia (flagellated protozoan) 101151 Hypsipyla robusta (cedar shoot borer) ENSP00000249923 Homo sapiens (human) ISCW012850-PA Ixodes scapularis (deer tick) KLLA0C15279g Kluyveromyces lactis (yeast) 183679 Lottia gigantea (owl limpet) LmjF20.1350 Leishmania major (virus) 38413 Monocosta brevicollis (choanoflagellate) ENSMODP00000009098 Monodelphis domestica (gray opossum) ENSMMUP00000021600 Macaca mulatta (rhesus monkey) ENSMUSP00000033012 Mus musculus (house mouse) 124098 Nematostella vectensis (starlet anemone) XP_001606861.1 Nasonia vitripennis (wasp) ENSOANP00000010972 Ornithorynchus anatinus (platypus) ENSORLP00000008536 Oryzias latipes (japanese killifish) LOC_Os01g17430.1 Oryza sativa (asian rice) 23611 Ostreococcus tauri (green alga) PF14_0277 Plasmodium falciparum (protozoal parasite) PHUM001625-PA Pediculus humanus (human body louse) PP16654 Pristionchus pacificus (nematode) 162358 Physcomitrella patens (moss) ENSPPYP00000003980 Pongo pygmaeus (orangutan) 80460 Phytophthora ramorum (sudden oak death pathogen) 108280 Phytophthora sojae (root rot pathogen) 578384 Populus trichocarpa (black cottonwood) ENSPTRP00000005903 Pan troglodytes (chimpanzee) PVX_085050 Plasmodium vivax (protozoal parasite) ENSRNOP00000016292 Rattus norvegicus (norway rat) 5052979 Sorghum bicolor (sorghum) YDR238C Saccharomyces cerevisiae (budding yeast) Smp_124430 Schistosoma mansoni (trematode parasite) SPBC146.14c Schizosaccharomyces pombe (fission yeast) 22765 Trichoplax adhaerens (metazoa) TA02765 Theileria annulata (apicomplexan parasite) XP_001816488.1 Tribolium castaneum (red flour beetle) Tc00.1047053506563.30 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012248 Tetraodon nigroviridis (green spotted pufferfish) TP01_0687 Theileria parva (parasitic protozoan) 26212 Thalassiosira pseudonana (marine diatom) ENSTRUP00000044513 Takifugu rubripes (pufferfish Takifugu) 60.m00135 Tetrahymena thermophila (ciliate protozoa) 92921.m00289 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000042611 Xenopus tropicalis (frog) YALI0F19074g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32820 modMine - Data generated by the modENCODE project. • FBgn0008635 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14345 LH20800 ISCW012850 FBgn0233107 FBgn0221862 FBgn0202398 FBgn0187305 FBgn0177690 JGI_V11_313075 FBgn0079449 FBgn0164618 FBgn0138348 FBgn0119831 FBgn0110343 FBgn0099505 CPIJ003330 BGIBMGA013717 ACYPI005687 ACYPI000894 GB13119 AGAP001399 AAEL004546 PB20395 PHUM055740 GLEAN_00641
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	BcDNA:GH09317   BcDNA.GH09317 (Rubin, 1999.4.23) bcop (Ripoche, 1994.4.14) BetaCop (Lum et al., 2003) betaCop (Giot et al., 2003, Cronin et al., 2009) Beta Cop (Southon et al., 2011) CG6223 (Hollien and Weissman, 2006, Ni et al., 2008, Ni et al., 2010.12.1, Keleman et al., 2009.8.5) β-COP (Bard et al., 2006, Hunter et al., 2002, Lewin and Mellman, 1998, Tear et al., 1996, Ripoche et al., 1994) βCOP (Grieder et al., 2005, Lecuit and Wieschaus, 2000, Nybakken et al., 2005, Beller et al., 2008, D'Ambrosio and Vale, 2010) β-Cop (Ramet et al., 2002, Ramet et al., 2002) βCop (Stroschein-Stevenson et al., 2006, Guo et al., 2008, Costello et al., 2009, Boyle et al., 2010) β-CopII (The et al., 1999)
Name Synonym	betaCop (Hollien and Weissman, 2006) β-coatomer protein
Secondary FlyBase IDs
References ( 43 )
Generate a list of	All references relating to this gene ( 43 )
List References by type	Research paper  ( 24 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 3 ) Curated genome annotation  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 3 )
	Southon et al., 2011, Int. J. Biochem. & Cell Biol. 43(1): 146--153 The ADP-ribosylation factor 1 (Arf1) is involved in regulating copper uptake. [FBrf0212662] Boyle et al., 2010, Dev. Biol. 346(1): 68--79 Division of labor: Subsets of dorsal-appendage-forming cells control the shape of the entire tube. [FBrf0211761] D'Ambrosio and Vale, 2010, J. Cell Biol. 191(3): 471--478 A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. [FBrf0212211] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...