T1, ASC-T1, P450, EG:165H7.1 , scγ
Please see the JBrowse view of Dmel\Cyp4g1 for information on other features
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Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
59 (kD)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cyp4g1 using the Feature Mapper tool.
Comment: maternal
Comment: induced after emergence
Cyt-P450-A1 protein was found in all insecticide resistant and susceptible strains tested.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Cyp4g1 in GBrowse 21-0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Cyp4g1 anon-WO0140519.102
Source for merge of Cyp4g1 anon-WO0140519.102 was sequence comparison ( date:051113 ).
The intronless Cyp4g1 gene is not a retrogene, as shown by the conserved synteny from Diptera to at least Hymenoptera.
Identified molecularly using degenerate PCR primers designed from conserved regions of known insect P450 genes.
Corresponds to cytochrome P450 A1 cDNA of FBrf0057534.
The adenylate cyclase inactivator forskolin and its pharmacologically inactive derivative 1,9-dideoxyforskolin inhibit, in a dose-dependent fashion, the ecdysone 20-monooxygenase activity associated with wandering stage larvae.
Transcription unit defined during molecular analysis of the achaete-scute complex.
Visualised as 59.3kD band on electrophoresis. Ubiquitous in all strains, irrespective of resistance to insecticides (Sundseth, Kennel and Waters, 1989). Monoclonal antibodies raised by Sundseth, Kennel and Waters (1989).