JH, JH esterase
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Jhe using the Feature Mapper tool.
Expressed cyclically in the adult fat body.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Jhe in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Ortholog of B. mori juvenile-hormone-related gene (involved in JH biosynthesis, metabolism or signaling).
Juvenile hormone metabolisms in two lines of adults is studied under normal conditions and after a short period of heat stress.
Heat stress results in delay of oviposition and a decrease in juvenile hormone hydrolysis and fertility, which lasted several days after heat treatment.
The course of changes in the activities of enzymes degrading juvenile hormone (JH) during development is studied and the possible role of the proteins in the regulation of JH titre in critical developmental periods and in reproduction are investigated.
Flies respond to stressing effects by a decrease in the level of Juvenile hormone (JH) hydrolysis, delay in oviposition and a decrease in fertility for a few days. The decrease in level of JH hydrolysis may be responsible for the response of the reproductive system to stress.
Radiometric assay showed juvenile hormone hydrolysing activity correlates inversely with juvenile hormone titre. Juvenile hormone esterase from D.melanogaster and D.simulans is sensitive to inhibition by esterase inhibitors OTFP and DFP.
Stage 8 and 9 oocytes transplanted into juvenile hormone (JH) deficient males and females were found to degenerate unless a JH analogue, ZR-515, was applied to the host shortly after implantation. These results suggest that JH is required for the initiation and continuation of vitellogenic uptake and oocyte development.