Gene Dmel\SteXh

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General Information

Symbol

Dmel\SteXh

Species

D. melanogaster

Name

Stellate in X heterochromatin

Annotation symbol

Feature type

repeat_region

FlyBase ID

FBgn0010086

Gene Model Status

Unannotated

Stock availability

None publicly available

Also Known As

Stellate 1; Stellate 2, hSte, Ste

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

h26-h26

Sequence location

Summary Information

Automatically generated summary

See sections below for more information

The gene Stellate in X heterochromatin is referred to in FlyBase by the symbol Dmel\SteXh (FBgn0010086). It is a repeat_region from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.

External Summaries

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2011_10

FB2012_01

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

h26-h26

Left limit from sequence databank entry X97132 Right limit from sequence databank entry X97132

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

h26-h26

(Tulin, 1996.4.4)

Experimentally Determined Recombination Data

Location

(Nurminsky, 1995.6.14)

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Expression Clusters

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of SteXh	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of SteXh	Class	Mutagen	Stocks	Known lesion
SteXh^cTa		in vitro construct	0	Yes

Aneuploid Aberrations

Disrupted in

Df(1)hSte

(Abramov et al., 2005, Rasheva et al., 1997)

Df(1)X-1

(Shevelyov, 1992)

Partially disrupted in

Df(1)12

(Abramov et al., 2005)

Duplicated in

Dp(1;Y)B^SYy⁺

(Shevelyov, 1992)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

characterization construct

P{SteXh^cTa}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

repeat_region

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

SteXh allele

Gene

References

External Data

Linkouts

Orthologs

Genome-wide drosophilid orthologs

Curated drosophilid orthologs

Linkouts

Stocks & Reagents

Stocks Listed in FlyBase ( 0 )

Genomic Clones ( 0 )

cDNA Clones ( 0 )

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

"Stellate-like" sequences (Ste, Su(Ste), SteXh and Ste12DOR) contain a common region of sequence, defined as the "Stellate-specific central core". Specific regions at either the 5' or 3' end of this core sequence distinguish different Stellate-like sequences from each other.

(Tritto et al., 2003)

Heterochromatic cluster containing Stellate repeats, cause PEV of a reporter mini-w gene.

(Tulin et al., 1998)

The structure and molecular diversity of the 30kb SteXh cluster in the distal heterochromatin of the X chromosome has been determined. The cluster comprises approximately 20 copies of tandemly repeated Stellate genes, 10 of which have been sequenced. Nine of these contain undamaged open reading frames which have extensive similarity to the CkIIβ gene. The cluster is divided into three regions by a 4.5kb DNA segment of unknown origin and a GATE retrotransposon insertion: the A region (containing approximately 14 Stellate genes), the adjacent B region (containing approximately 3 Stellate genes), and the C region (containing approximately 4 Stellate genes).

(Tulin et al., 1997)

60kb repeats located in the distal heterochromatin of the X chromosome have been cloned. These regions, designated as SCLRs, are comprised of the following types of repeated elements: SteXh, copia-like elements (mdg1 elements, aurora-elements and GATE elements), LINE-elements (G-elements and R1-elements), and bb fragments. There are approximately 9 SCLR copies per haploid genome, with a twofold variation in copy number between different fly stocks.

(Nurminsky et al., 1994)

The relationship of Ste copy number and organisation to meiotic behaviour in Su(Ste)^- males has been examined genetically and cytologically. Heterochromatic and euchromatic Ste repeats are functional, the abnormalities in chromosome condensation and frequency of nondisjunction is related to the Ste copy number. Meiosis is disrupted after synapsis and Su(Ste) induced meiotic drive is probably not mediated by Ste.

(Palumbo et al., 1994)

Two variants of X chromosome Stellate genes occupy different genome positions. The majority of 1250bp Stellate repeats map at 12E (location of Ste) but almost all of the 1150bp Stellate repeats are in the distal X heterochromatin (at SteXh). Some of the heterochromatic copies are expressed.

(Shevelyov, 1992)

External Crossreferences & Linkouts

Sequence Crossreferences

DDBJ / EMBL / GenBank

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