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Gene Dmel\γTub37C

General Information
Symbol	Dmel\γTub37C	Species	D. melanogaster
Name	γ-Tubulin at 37C	Annotation symbol	CG17566
Feature type	protein_coding_gene	FlyBase ID	FBgn0010097
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	fs(2)TW1, γTUB, γTub37CD, γ-Tub, γ-Tub37C, gammaTub37C
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	37C7-37C7	Sequence location	2L:19,183,970..19,185,724 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene γ-Tubulin at 37C is referred to in FlyBase by the symbol Dmel\γTub37C (CG17566, FBgn0010097). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: GTP binding. There is experimental evidence that it is involved in the biological process: spindle assembly involved in female meiosis I; attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification. 27 alleles are reported. The phenotypes of these alleles are annotated with: condensed nuclear chromosome; meiotic metaphase I; polar body nucleus; oocyte; cleavage stage embryo; meiotic spindle; spindle; oocyte nucleus; nucleus. It has one annotated transcript and one annotated polypeptide. Protein features are: Gamma tubulin; Tubulin; Tubulin, C-terminal; Tubulin, conserved site; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, GTPase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1639192_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of gammaTub37C. Gene sequence location is 2L:19183970..19185724.
External Summaries
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	fs(2)TW1: female sterile (2) Ted Wright 1 Eggs produced by homozygous females show no visible signs of development (Schupbach, and Wieschaus, 1989, Genetics 121: 101-17).
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Controlled Vocabulary Terms cell cell embryonic stage
FB2012_01	Sequence features BKN30694 HFA03535
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 37C7-37C7   Limits computationally determined from genome sequence between P{lacW}bratk06028&P{lacW}l(2)k09613k09613 and P{EP}dntEP2158
Experimentally Determined Cytological Location
Cytogenetic map Notes References 37C-37D   (determined by in situ hybridisation)   (Wilson et al., 1997) 37C-37C   (determined by in situ hybridisation)   (Tavosanis et al., 1997) 37C-37C     (Tavosanis et al., 1996) 37D-37D   (determined by in situ hybridisation)   (Bolwig et al., 1995)
Experimentally Determined Recombination Data
Location	2-54 (Schupbach and Wieschaus, 1989) 2- (Tavosanis et al., 1996)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\γTub37C for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) γTub37C-RA FBtr0081228  NM_057574   1519   457
Additional Transcript Data & Comments
Reported size (kB)	1.553 (unknown) (Wilson et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein γTub37C-PA   FBpp0080769   51.3   457   6.25     NP_476922   AAF53774
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tubulin (IPR000217) Gamma tubulin (IPR002454) Tubulin/FtsZ, GTPase domain (IPR003008) Tubulin/FtsZ, C-terminal (IPR008280) Tubulin, conserved site (IPR017975) Tubulin/FtsZ, 2-layer sandwich domain (IPR018316) Tubulin, C-terminal (IPR023123)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA951884   AE014134 AAF53774   AC005440   AC007176   AC010009   AC092187   AF081252 AAC35843   AF081253 AAC35844   AF091265 AAC64117   AI541751   AJ010552 CAA09233   AW943148   AY070558 AAL48029   BI635855   BI640016   BX011263   CO176963   CO265511   CO267095   CO327170   CO329876   CZ478637   EC061392   EC078820   EC078873   EC200650   EC210338   EC217510   EC256563   EL869858   EL869859   EL869860   EL869861   GH943613   GH945307   GH945706   GH948506   GH959143   GH965687   GH966284   GH968970   GH970445   GH971383   GH980096   GH980596   GH983000   M76765 AAB52553
UniProtKB/Swiss-Prot	P42271
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   cell   • centrosome (Vidwans et al., 1999)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0010097    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0010097 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0010097 expression level Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (9295) embryo 02-04hr  (619) embryo 04-06hr  (207) embryo 06-08hr  (120) embryo 08-10hr  (114) embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day  (2527) adult female 05day  (5574) adult female 30day  (5065) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (9295) embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day  (2527) adult female 05day  (5574) adult female 30day  (5065) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0010097 expression level Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (9295) embryo 02-04hr  (619) embryo 04-06hr  (207) embryo 06-08hr  120 embryo 08-10hr  114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day  (2527) adult female 05day  (5574) adult female 30day  (5065) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (9295) embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day  (2527) adult female 05day  (5574) adult female 30day  (5065) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    9295 embryo 02-04hr    619 embryo 04-06hr    207 embryo 06-08hr    120 embryo 08-10hr    114 embryo 10-12hr    48 embryo 12-14hr    36 embryo 14-16hr    61 embryo 16-18hr    17 embryo 18-20hr    36 embryo 20-22hr    11 embryo 22-24hr    21 larva L1    4 larva L2    4 larva L3 12hr old    2 larva L3 puffstage 1-2    24 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    37 white prepupae 24hr    17 pupae 2d postWPP    28 pupae 3d postWPP    16 pupae 4d postWPP    67 adult male 01day    10 adult male 05day    20 adult male 30day    35 adult female 01day    2527 adult female 05day    5574 adult female 30day    5065 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0010097    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0010097 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0010097 expression level Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0010097 expression level Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    27.775 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    6.225 Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain    9.1 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut    15.7 Adult Malpighian Tubules    8.1 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    4.675 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    410.9 Adult Testis    7.4 Adult Male Accessory Gland no informative data Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea     Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain     Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    no informative data   NA  Brain    9.1   27.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   no informative data  Midgut    no informative data   no informative data  Hindgut    15.7   no informative data  Malpighian Tubules    8.1   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    4.675   6.225  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    410.9   NA  Testis    7.4   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010097 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17566-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | non-rescuable maternal effect | recessive γTub37Cunspecified lethal | embryonic stage | recessive γTub37C1 viable γTub37C139 viable, with Scer\GAL4pnr-MD237 γTub37CGD9416 Sterility Allele female sterile γTub37C1 γTub37C2 γTub37C3 γTub37C4 γTub37C5 γTub37C6 γTub37C7 γTub37C8 γTub37C9 γTub37C10 γTub37C11 γTub37C12 γTub37C13 γTub37C14 γTub37C15 γTub37C139 γTub37CC15 female sterile (with Df(2L)VA23) γTub37C11 female sterile | recessive γTub37C1 γTub37C3 γTub37CP162L γTub37Cunspecified male fertile γTub37C1 γTub37CP162L Other Phenotypes Allele meiotic cell cycle defective γTub37CP162L meiotic cell cycle defective (with Df(2L)Exel6043) γTub37C3 mitotic cell cycle defective | maternal effect γTub37Cunspecified wild-type γTub37C+t7.2 Phenotype manifest in Allele aster | embryonic stage γTub37C1 centrosome | maternal effect (with Df(2L)TE37C-7) γTub37C11 γTub37C12 γTub37C13 γTub37C15 cleavage stage embryo γTub37C1 γTub37C12 γTub37C13 condensed nuclear chromosome γTub37CP162L condensed nuclear chromosome (with Df(2L)Exel6043) γTub37C3 egg & spindle (with Df(2L)TE37C-7) γTub37C3 embryo & mitosis & nuclear chromosome γTub37C1 γTub37C12 meiotic metaphase I γTub37C1 γTub37C12 γTub37C13 meiotic spindle γTub37CP162L meiotic spindle (with Df(2L)Exel6043) γTub37C3 nucleus (with γTub37C1) γTub37C3 nucleus (with γTub37C3) γTub37C1 oocyte (with Df(2L)TE37C-7) γTub37C3 oocyte (with γTub37C1) γTub37C3 oocyte (with γTub37C3) γTub37C1 oocyte nucleus γTub37CP162L oocyte nucleus (with Df(2L)Exel6043) γTub37C3 ovariole | germline clone γTub37C139 polar body nucleus γTub37C1 γTub37C12 polar body nucleus (with Df(2L)TE37C-7) γTub37C3 polar body nucleus (with γTub37C1) γTub37C3 polar body nucleus (with γTub37C3) γTub37C1 polar body nucleus | maternal effect (with Df(2L)TE37C-7) γTub37C12 spindle γTub37C1 γTub37C12 γTub37C13 γTub37CdsRNA.cMa spindle & oocyte (with γTub37C1) γTub37C3 spindle & oocyte (with γTub37C3) γTub37C1 spindle | cleavage stage | maternal effect γTub37Cunspecified spindle | embryonic stage γTub37C1 γTub37C12 spindle | maternal effect (with Df(2L)TE37C-7) γTub37C12
Classical Alleles ( 19 )
For All Classical Alleles Show
Allele of γTub37C Class Mutagen Stocks Known lesion γTub37C1 ethyl methanesulfonate 2 Yes γTub37C3 2 Yes γTub37Ce00793 piggyBac transposase 1 -- γTub37C10 0 -- γTub37C11 ethyl methanesulfonate 0 Yes γTub37C12 hypomorphic allele - genetic evidence ethyl methanesulfonate 0 Yes γTub37C139 ethyl methanesulfonate 0 -- γTub37C13 ethyl methanesulfonate 0 Yes γTub37C14 0 -- γTub37C15 0 Yes γTub37C2 0 -- γTub37C4 0 -- γTub37C5 0 -- γTub37C6 0 -- γTub37C7 0 -- γTub37C8 0 -- γTub37C9 0 -- γTub37CP162L ethyl methanesulfonate 0 Yes γTub37Cunspecified ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of γTub37C Class Mutagen Stocks Known lesion γTub37CGD9416 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes γTub37CHMS00517 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes γTub37C+t7.2 in vitro construct - genomic fragment 0 Yes γTub37CC15 in vitro construct - genomic fragment 0 Yes γTub37CdsRNA.cMa in vitro construct - RNAi 0 Yes γTub37CE116R.ncd.T:Avic\GFP-S65T in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - amino acid replacement 0 Yes γTub37CKK110694 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes γTub37Cncd.T:Avic\GFP-S65T in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6043 (Ryder, 2004.4.26) Df(2L)NST (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd57 (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd77 (Stathakis et al., 1995, Wright, 1996) Df(2L)TE37C-1 (Wright, 1996) Df(2L)TE37C-7 (Stathakis et al., 1995, Wright, 1996) Df(2L)TW50 (Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991) Df(2L)TW130 (Schnorrer et al., 2002, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991, Stathakis et al., 1995, Wright, 1996) Df(2L)TW150 (Schnorrer et al., 2002) Df(2L)TW158 (Schnorrer et al., 2002, Tavosanis et al., 1997) Df(2L)VA12 (Stathakis et al., 1995, Wright, 1996) Df(2L)VA13 (Wright, 1996) Df(2L)VA16 (Schnorrer et al., 2002) Df(2L)VA17 (Stathakis et al., 1995, Wright, 1996) Df(2L)VA19 (Stathakis et al., 1995, Wright, 1996, Tavosanis et al., 1997) Df(2L)VA23 (Stathakis et al., 1995, Tavosanis et al., 1997, Hallen et al., 2008)
Not disrupted in	Df(2L)E55 (Stathakis et al., 1995) Df(2L)hk18 (Wright, 1996) Df(2L)hk-UC1 (Stathakis et al., 1995, Wright, 1996) Df(2L)hk-UC2 (Stathakis et al., 1995, Wright, 1996) Df(2L)OD15 (Stathakis et al., 1995, Wright, 1996, Digilio et al., 1996) Df(2L)Sd37 (Stathakis et al., 1995, Wright, 1996) Df(2L)TW137 (Stathakis et al., 1995) Df(2L)TW203 (Stathakis et al., 1995, Wright, 1996) Df(2L)VA6 (Tavosanis et al., 1997) Df(2L)VA18 (Stathakis et al., 1995, Wright, 1996, Tavosanis et al., 1997) Df(2L)VA21 (Stathakis et al., 1995, Wright, 1996) Df(2L)γ244 (Digilio et al., 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data characterization construct P{pC15} NA P{γTub37C+} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}γTub37Ce00793 NA
Gene Ontology: Function, Process & Cellular Component ( 18 unique terms )
Terms Based on Experimental Evidence ( 10 terms )
Molecular Function
CV term Evidence References
GTP binding inferred from direct assay (Gunawardane et al., 2003)
Biological Process
CV term Evidence References
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation inferred from mutant phenotype (Hughes et al., 2011) oocyte nucleus localization involved in oocyte dorsal/ventral axis specification inferred from mutant phenotype (Hughes et al., 2011) spindle assembly involved in female meiosis I inferred from mutant phenotype (Hughes et al., 2011)
Cellular Component
CV term Evidence References
centrosome inferred from direct assay (Hallen et al., 2008) cytoplasm inferred from direct assay (Hallen et al., 2008) gamma-tubulin small complex inferred from direct assay (FlyBase, 1992-) meiotic spindle inferred from direct assay (Hughes et al., 2011) microtubule associated complex inferred from direct assay (Hughes et al., 2008) spindle inferred from direct assay (Hallen et al., 2008)
Terms Based on Predictions or Assertions ( 8 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from electronic annotation with InterPro:IPR008280, InterPro:IPR018316 (FlyBase Curators et al., 2004-) structural constituent of cytoskeleton inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000, Goldstein and Gunawardena, 2000)
Biological Process
CV term Evidence References
GTP catabolic process inferred from electronic annotation with InterPro:IPR008280, InterPro:IPR018316 (FlyBase Curators et al., 2004-) microtubule-based process inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000) non-traceable author statement (Swiss-Prot Project Members, 1995.6.1) protein polymerization inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280, InterPro:IPR018316 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
microtubule inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000, Goldstein and Gunawardena, 2000, Oakley, 1991.10.4) inferred from sequence or structural similarity with UniProtKB:P23330 (FlyBase, 1992-) microtubule organizing center inferred from sequence or structural similarity (Oakley, 1991.10.4) non-traceable author statement (Swiss-Prot Project Members, 1995.6.1) tubulin complex non-traceable author statement (Swiss-Prot Project Members, 1995.6.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions γTub37C allele Gene References γTub37C1 E(γTub37C1) (Bloomington Drosophila Stock Center, 1997.12.5) γTub23C (Tavosanis and Gonzalez, 2003) γTub37C11 ncd (Endow and Komma, 1998) γTub37C12 ncd (Endow and Komma, 1998) γTub23C (Tavosanis and Gonzalez, 2003) γTub37C13 ncd (Endow and Komma, 1998)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61183 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010097 DroID - A comprehensive database of gene and protein interactions. • FBgn0010097 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35199
Orthologs
Genome-wide drosophilid orthologs	Dere\GG21644 Dgri\GH13477 Dmoj\GI17230 Dper\GL21122 Dpse\GA14559 Dsec\GM17021 Dsim\GD21771 Dyak\GE12662
Curated drosophilid orthologs	Dpse\GA14559
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • At3g61650.1 Arabidopsis thaliana (wall cress) At5g05620.1 Arabidopsis thaliana (wall cress) 11643 Batrachochytrium dendrobatidis (chytrid fungus) CN15957 Caenorhabditis brenneri (small nematode) CBP02441 Caenorhabditis briggsae (nematode) CE00224 Caenorhabditis elegans (worm) JA09646 Caenorhabditis japonica (nematode) CMN304C Cyanidioschyzon merolae (red alga) 188933 Chlamidomonas reinhardtii (green alga) RP38389 Caenorhabditis remanei (nematode) DDB0185068 Dictyostelium discoideum (amoeba) LmjF25.0960 Leishmania major (virus) LOC_Os05g06450.1 Oryza sativa (asian rice) 25029 Ostreococcus tauri (green alga) PF08_0125 Plasmodium falciparum (protozoal parasite) PP11569 Pristionchus pacificus (nematode) 170153 Physcomitrella patens (moss) 170860 Physcomitrella patens (moss) 109415 Phytophthora sojae (root rot pathogen) 572355 Populus trichocarpa (black cottonwood) 755367 Populus trichocarpa (black cottonwood) 4894033 Sorghum bicolor (sorghum) 29237 Thalassiosira pseudonana (marine diatom) 3828.m01461 Tetrahymena thermophila (ciliate protozoa) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16082 LH19286 FBgn0235626 FBgn0230389 FBgn0226809 FBgn0225811 FBgn0205155 FBgn0205114 FBgn0194585 FBgn0193192 FBgn0173288 FBgn0171933 JGI_V11_301492 FBgn0076344 FBgn0074587 FBgn0163882 FBgn0158717 FBgn0140346 FBgn0139974 FBgn0260639 FBgn0120953 FBgn0118566 FBgn0117032 FBgn0113822 FBgn0092229 FBgn0092018 CPIJ005487 BGIBMGA013500 ACYPI004513 GB18755 AGAP007834 AAEL013064 AAEL012843 PB24138 PHUM087820 GLEAN_14883
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	4201 γTub37C3/CyO 32513 y1 sc* v1; P{TRiP.HMS00517}attP2 3188 E(γTub37C1)1 γTub37C1 pr1 Ddcts1/CyO
Harvard	- PBac{RB}γTub37Ce00793
Kyoto	107628 γTub37C3/CyO 106902 E(γTub37C1)1 γTub37C1 pr1 Ddcts1/CyO
VDRC	v25271 w1118; P{GD9416}v25271 v25272 w1118; P{GD9416}v25272
Genomic Clones ( 2 )
	BACR10I09 BACR48O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 32 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD32755
Other clones	DPiM_LD32755
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	SD06894 SD17375 SD22768
Other clones	33051 34432 63510 190464 191281 214415.29 CK01.12C.G1 EK051821 EK142838 EK148720 EK294057 EP06229 IP01977 IP01979 RP004011728 RP004195654 RP004214509 RP004227314 RP004232509 RP004239857 RP004245241 RP004248675 RP004413279 RP004426804 RP004447881 RP004481757 RP004489640
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010097 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35199
Antibody Information
	polyclonal (Wiese, 2008)
Other Information
Discoverer
	T.R.F. Wright.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Eight independent occurrences recovered by Wright, four more by Schupbach.
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) sub mutants do not interact with alleles of γTub37C, αTub67C, msps, tacc or wisp. (Giunta et al., 2002) γTub37C is essential for nuclear proliferation in the early embryo. (Llamazares et al., 1999) Phenotypic rescue of fs(2)TW1 mutants by a γTub37C construct demonstrates γTub37C and fs(2)TW1 are the same gene. This conclusion is substantiated further by the perfect agreement between the restriction maps. (Tavosanis et al., 1997) Expression of γTub37C is under strict developmental regulation and the organisation of the female meiotic spindle requires γTub37C. γTub37C gene product provides a function which is essential exclusively for female fertility. (Tavosanis et al., 1997) Immunoblot analysis and immunolocalisation show that γTub23C and γTub37C are differentially expressed during gametogenesis and development. (Wilson et al., 1997) Maternal effect mutant that affects early embryogenesis. (Digilio et al., 1996) Subcellular localisation of the protein during the cell cycle of cells with and without centrioles is determined. Data suggests centrioles are not essential to the formation of a functional mitotic spindle, but participate in the focal concentration of γTub23C and γTub37C protein during both interphase and mitosis. (Debec et al., 1995) Located between coordinates +50.1 and +60.1. (Stathakis et al., 1995) Mutations in γTub37C show a maternal effect with defects in fertilisation or very early embryonic development. (Schupbach and Wieschaus, 1989) Identification: Saturation mutagenesis of Df(2L)TW130.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057574 RefSeq (Proteins) • NP_476922 DDBJ / EMBL / GenBank • AA951884 AAB52553 AAC35843 AAC35844 AAC64117 AAF53774 AAL48029 AC005440 AC007176 AC010009 AC092187 AF081252 AF081253 AF091265 AJ010552 AW943148 AY070558 CAA09233 CZ478637 M76765 Entrez Gene - A searchable database of RefSeq genes. • 35199 UniProtKB/Swiss-Prot • P42271
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tubulin (IPR000217) Gamma tubulin (IPR002454) Tubulin/FtsZ, GTPase domain (IPR003008) Tubulin/FtsZ, C-terminal (IPR008280) Tubulin, conserved site (IPR017975) Tubulin/FtsZ, 2-layer sandwich domain (IPR018316) Tubulin, C-terminal (IPR023123)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61183 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010097 DroID - A comprehensive database of gene and protein interactions. • FBgn0010097 DRSC - Results from RNAi screens. • FBgn0010097 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010097 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17566-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010097 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35199 InParanoid A subset of ortholog calls from InParanoid. • At3g61650.1 Arabidopsis thaliana (wall cress) At5g05620.1 Arabidopsis thaliana (wall cress) 11643 Batrachochytrium dendrobatidis (chytrid fungus) CN15957 Caenorhabditis brenneri (small nematode) CBP02441 Caenorhabditis briggsae (nematode) CE00224 Caenorhabditis elegans (worm) JA09646 Caenorhabditis japonica (nematode) CMN304C Cyanidioschyzon merolae (red alga) 188933 Chlamidomonas reinhardtii (green alga) RP38389 Caenorhabditis remanei (nematode) DDB0185068 Dictyostelium discoideum (amoeba) LmjF25.0960 Leishmania major (virus) LOC_Os05g06450.1 Oryza sativa (asian rice) 25029 Ostreococcus tauri (green alga) PF08_0125 Plasmodium falciparum (protozoal parasite) PP11569 Pristionchus pacificus (nematode) 170153 Physcomitrella patens (moss) 170860 Physcomitrella patens (moss) 109415 Phytophthora sojae (root rot pathogen) 572355 Populus trichocarpa (black cottonwood) 755367 Populus trichocarpa (black cottonwood) 4894033 Sorghum bicolor (sorghum) 29237 Thalassiosira pseudonana (marine diatom) 3828.m01461 Tetrahymena thermophila (ciliate protozoa) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /cytoskel/tubg2-1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35199 modMine - Data generated by the modENCODE project. • FBgn0010097 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16082 LH19286 FBgn0235626 FBgn0230389 FBgn0226809 FBgn0225811 FBgn0205155 FBgn0205114 FBgn0194585 FBgn0193192 FBgn0173288 FBgn0171933 JGI_V11_301492 FBgn0076344 FBgn0074587 FBgn0163882 FBgn0158717 FBgn0140346 FBgn0139974 FBgn0260639 FBgn0120953 FBgn0118566 FBgn0117032 FBgn0113822 FBgn0092229 FBgn0092018 CPIJ005487 BGIBMGA013500 ACYPI004513 GB18755 AGAP007834 AAEL013064 AAEL012843 PB24138 PHUM087820 GLEAN_14883
Synonyms & Secondary IDs ( 40 )
Reported As
Symbol Synonym	CG17566 (Goldstein and Gunawardena, 2000, Hughes et al., 2008, Ni et al., 2010.12.1, Keleman et al., 2009.8.5) D.m.GAMMA-37C (Goldstein and Gunawardena, 2000) fs(2)TW1 (Tavosanis and Gonzalez, 2003, Tadros et al., 2003, Wright, 1996, Stathakis et al., 1995, Schupbach and Wieschaus, 1989, ) fs(2)TWI (Gateff and Mechler, 1989) fsTW1 (McCrady and Tolin, 1994) gammaTub37C (Giot et al., 2003, Bakal et al., 2007) gamma Tub37CD (Wilson, 1998.9.8) gamma tubulin (Zhang and Megraw, 2006) GTU88* (Martinez-Campos et al., 2004) g-Tubulin (Hutterer et al., 2003) PL10 (Digilio et al., 1996) Rb1011 (Tavosanis and Gonzalez, 2003) TW1 (Wright, 1996) γmat (Wilson et al., 1992) γ-Tub (Pelissier et al., 2003, de Carcer et al., 2001, Zhang and Megraw, 2007) γTUB (Herzig et al., 2002) γtub (Harris and Peifer, 2004) γTub (Pai et al., 2004, Barros et al., 2005, Orian et al., 2007) γTub2   γ-Tub37C (Ephrussi and St. Johnston, 2004, Rogers et al., 2008, Jang et al., 2005) γTUB37C (Tavosanis et al., 1997, Janic et al., 2010) γTub37C (Delanoue and Davis, 2005, McCrady and Tolin, 1994, Vogt et al., 2006, Vázquez et al., 2008, Rogers et al., 2008, Januschke et al., 2006, Hallen et al., 2008, Hughes et al., 2011) γTub37CD (Wilson, 1999.12.22, Wilson and Borisy, 1998, Wilson and Borisy, 1998, Wiese, 2008, Raynaud-Messina et al., 2004) γ-tub37CD (Raynaud-Messina et al., 2001) γ-tubulin (Bettencourt-Dias et al., 2004) γ tubulin (Riparbelli et al., 2002)
Name Synonym	37CD γ-tubulin (Raynaud-Messina et al., 2004) female sterile(2)Ted Wright 1   gama-tubulin (Moutinho-Santos et al., 2001) gamma-tubulin (Kaltschmidt and Brand, 2002, Oakley, 1991.10.4, Jeng and Stearns, 1999, Endow and Komma, 1998, Vied and Horabin, 1999, Rusan and Peifer, 2007, Martins et al., 2007) gamma tubulin (Megraw et al., 2000, Donaldson et al., 2001, Grieder et al., 2000) Gamma Tubulin at 37C (Ducat et al., 2008) maternal γ-tubulin (Schnorrer et al., 2002) tubulin (Goshima et al., 2005, Ashley et al., 2005, Yuen et al., 2008) γ tubulin (Fischer et al., 2004, Lee et al., 2001, Gunawardane et al., 2000, Schaefer et al., 2001, Donaldson et al., 2001, Foe et al., 2000, Zimmerman et al., 1999, Avides and Glover, 1999, Carmena et al., 1998, Moritz et al., 1998, Helps et al., 1998, Riparbelli et al., 1997, Stumpff et al., 2004, Goshima and Vale, 2003, Harris and Peifer, 2005) γ-tubulin (Salisbury, 2004, Januschke et al., 2005, Kwon and Scholey, 2004, Cottam et al., 2004, Greaves, 2001, Fuse et al., 2003, Albertson and Doe, 2003, Mathe et al., 2003, Gergely, 2002, Mollinari et al., 2002, Ohkura et al., 2001, Lee et al., 2001, Wakefield et al., 2001, Bolivar et al., 2001, MacDougall et al., 2001, Huynh et al., 2001, Ceron et al., 2001, Megraw et al., 2001, Gunawardane et al., 2000, Barbosa et al., 2000, Riparbelli et al., 2000, Grieder et al., 2000, Callaini et al., 1999, Su and Vidwans, 2000, Moritz et al., 2000, Lemos et al., 2000, Lange et al., 2000, Brent et al., 2000, Afshar et al., 2000, Sibon et al., 2000, Vidwans et al., 1999, Moutinho-Santos et al., 1999, Gunawardane et al., 1999, Bonaccorsi et al., 2000, Swan et al., 1999, Vaizel-Ohayon and Schejter, 1999, Gho et al., 1999, Robinson et al., 1999, Megraw et al., 1999, Oegema et al., 1999, Bamburg et al., 1999, Herrmann et al., 1998, Lajoie-Mazenc et al., 1994, Marshall, 1998, Riparbelli and Callaini, 1998, Davis, 1997, Callaini et al., 1997, Moritz et al., 1995, Moritz and Alberts, 1992, Wilson et al., 2004, Silvanovich et al., 2003, Gunawardane et al., 2003, Roper and Brown, 2004, Verollet et al., 2006, Goshima et al., 2007, Wilson, 2005, Harris and Peifer, 2004, Yamashita et al., 2007, Yamashita et al., 2007, Barros et al., 2005, Goshima et al., 2005, Rodrigues-Martins et al., 2007, Morales-Mulia and Scholey, 2005, Mottier et al., 2008, Blagden and Glover, 2003, Zhang et al., 2007, Goshima et al., 2008, Tan et al., 2008, Wei et al., 2008, Trammell et al., 2008, Blachon et al., 2008, Colombié et al., 2008, Yang and Fan, 2008, Peel et al., 2007, Bucciarelli et al., 2009, Conduit and Raff, 2010) γ-Tubulin (Cha et al., 2002, Berdnik and Knoblich, 2002, Berdnik et al., 2001, Riparbelli et al., 2004, Megraw et al., 2008, Colombie et al., 2006, Rickmyre et al., 2007) γtubulin (Wilson, 2001, Kaltschmidt et al., 2000, Wilson, 1999, Wilson, 1999, Craig and Brink, 1996, Terada et al., 2003, Leatherman and Dinardo, 2010) γTubulin (Wang and Riechmann, 2008) γ-tubulin-2 (Debec et al., 1995) γ Tubulin2   γ-tubulin (37C) (M Mahoney, 2006) γ-Tubulin at 37C
Secondary FlyBase IDs
	FBgn0001003
References ( 226 )
Generate a list of	All references relating to this gene ( 226 )
List References by type	Research paper  ( 139 ) Supplementary material  ( 11 ) Review  ( 21 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 30 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 5 ) Conference report  ( 2 ) Protein sequence record  ( 1 ) Stock list  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 ) Book  ( 1 )
Recent research papers ( 4 )
	Hughes et al., 2011, PLoS Genet. 7(8): e1002209 Gamma-Tubulin Is Required for Bipolar Spindle Assembly and for Proper Kinetochore Microtubule Attachments during Prometaphase I in Drosophila Oocytes. [FBrf0214729] Conduit and Raff, 2010, Curr. Biol. 20(24): 2187--2192 Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts. [FBrf0212663] Janic et al., 2010, Science 330(6012): 1824--1827 Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila. [FBrf0212713] Leatherman and Dinardo, 2010, Nat. Cell Biol. 12(8): 806--811 Germline self-renewal requires cyst stem cells and stat regulates niche adhesion in Drosophila testes. [FBrf0211422] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...