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Gene Dmel\RpS13

General Information
Symbol	Dmel\RpS13	Species	D. melanogaster
Name	Ribosomal protein S13	Annotation symbol	CG13389
Feature type	protein_coding_gene	FlyBase ID	FBgn0010265
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	M(2)32A
Genomic Location
Chromosome (arm)	2L	Recombination map	2-
Cytogenetic map	29B2-29B2	Sequence location	2L:8,363,699..8,364,609 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein S13 is referred to in FlyBase by the symbol Dmel\RpS13 (CG13389, FBgn0010265). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization. 10 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; adult heart; scutellar bristle; prothoracic gland. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ribosomal protein S13/S15, N-terminal; Ribosomal protein S15; Ribosomal protein S15P; S15/NS1, RNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635303_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of RpS13. Gene sequence location is 2L:8363699..8364609.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29B2-29B2   Limits computationally determined from genome sequence between P{EP}EP646EP646&P{lacW}RpS13k09614 and P{lacW}l(2)k12914k12914&P{lacW}Akap200k07118a
Experimentally Determined Cytological Location
Cytogenetic map Notes References 32A-32A     (Saeboe-Larsson, 1995.9.26) 29A-29A     (Ashburner, 1992.12.9) 29B1-29B2   (determined by in situ hybridisation)   (Spradling et al., 1999) 32A-32A   (determined by in situ hybridisation)   (Saeboe-Larssen and Lambertsson, 1996) 29B1-29B2     (BDGP Project Members, 1994-1999) 29A-29A   (determined by in situ hybridisation)   (McNabb and Ashburner, 1993)
Experimentally Determined Recombination Data
Location	2- (Saeboe-Larsson, 1995.9.26) 2-42 (Saeboe-Larssen and Lambertsson, 1996)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpS13 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpS13-RA FBtr0079724  NM_057590   624   151 RpS13-RB FBtr0100541  NM_001038796   611   151
Additional Transcript Data & Comments
Reported size (kB)	0.74 (northern blot) (McNabb and Ashburner, 1993) 0.6 (northern blot) (Saeboe-Larssen and Lambertsson, 1996)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpS13-PA   FBpp0079328   17.2   151   11.24     NP_476938   AAF52649 RpS13-PB   FBpp0099990   17.2   151   11.24     NP_001033885   ABC65883
Additional Polypeptide Data & Comments
Reported size (kDa)	151 (aa); 17 (kD predicted) (Saeboe-Larssen and Lambertsson, 1996) 151 (aa); 17 (kD) (McNabb and Ashburner, 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S15 (IPR000589) S15/NS1, RNA-binding (IPR009068) Ribosomal protein S13/S15, N-terminal (IPR012606) Ribosomal protein S15P (IPR023029)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263839   AA567067   AA567161   AA696873   AA735308   AA820377   AA952041   AA952243   AE014134 AAF52649   AE014134 ABC65883   AC004281   AC005555   AC092220   AI064133   AI064389   AI064504   AI108088   AI108163   AI108874   AI133950   AI135909   AI238168   AI239232   AI256976   AI260173   AI261022   AI294548   AI295992   AI296667   AI296926   AI296968   AI389119   AI402383   AI404508   AI404611   AI404641   AI455407   AI513855   AQ025899   AY058536 AAL13765   AY231876   AY232093   AY432144   AY439354   BF489257   BF490058   BG633080   BG635448   BG635565   BG636522   BG636645   BG636853   BG640313   BG640391   BG640398   BG640408   BG641099   BG641433   BG641453   BI141761   BI142202   BI142239   BI162062   BI162063   BI164647   BI165406   BI166398   BI167039   BI167421   BI168987   BI169686   BI170286   BI170465   BI171338   BI173296   BI212284   BI212594   BI214417   BI215461   BI216623   BI228783   BI230859   BI231675   BI232435   BI233014   BI233034   BI234546   BI234771   BI235241   BI235547   BI235743   BI239118   BI239307   BI240089   BI240844   BI242546   BI243657   BI351636   BI351787   BI351909   BI351964   BI352166   BI352316   BI352318   BI352721   BI352770   BI352914   BI353566   BI353841   BI354689   BI355171   BI355540   BI355795   BI357634   BI358399   BI361817   BI361917   BI362532   BI363029   BI366830   BI368592   BI369764   BI373141   BI373195   BI373870   BI375716   BI482310   BI484668   BI484699   BI564621   BI568128   BI569960   BI575634   BI577166   BI577212   BI578427   BI579736   BI579886   BI580295   BI580469   BI580629   BI589801   BI604319   BI606480   BI607293   BI607474   BI610214   BI610482   BI611150   BI613923   BI614043   BI614825   BI616480   BI619467   BI619705   BI621190   BI621191   BI621225   BI624897   BI624963   BI630729   BI632249   BI632287   BI632307   BI632528   BI632760   BI632783   BI632874   BI633286   BI633416   BI633922   BI636089   BI636455   BI636881   BI638367   BI639115   BI639666   BI639906   BI640545   BI640581   BI640596   BI641627   BI641813   BP540610   BP540611   BP541085   BP541086   BP541188   BP541189   BP541449   BP541571   BP541980   BP542199   BP542236   BP542582   BP542719   BP543577   BP543578   BP543608   BP543609   BP543797   BP543798   BP544094   BP544095   BP544102   BP544118   BP544119   BP544425   BP544426   BP544466   BP544467   BP544650   BP544651   BP544828   BP544829   BP544893   BP544894   BP544988   BP544989   BP545310   BP545311   BP545640   BP545641   BP545701   BP545702   BP545785   BP545901   BP545938   BP546067   BP546237   BP546253   BP546734   BP546971   BP547067   BP547150   BP547989   BP548002   BP548391   BP548536   BP548612   BP548658   BP548676   BP548954   BP548955   BP549330   BP549331   BP549424   BP549425   BP550027   BP550028   BP550144   BP550145   BP551106   BP551107   BP551416   BP551417   BP552015   BP552101   BP552762   BP552763   BP552935   BP552936   BP553120   BP553121   BP553578   BP554827   BP554989   BP555015   BP555016   BP555137   BP555138   BP555261   BP555262   BP555284   BP555665   BP555666   BP555837   BP555838   BP555847   BP555848   BP556707   BP556708   BP556926   BP556927   BP557141   BP557527   BP557528   BX007284   BX007616   BX008717   BX012011   BX014904   BX020329   BX020681   BX022140   BX023299   BX024738   BX028519   BX037518   BX037556   BX037594   BX037893   BX038098   BX038136   BX038250   BX038264   BX038443   BX039120   BX047055   BX061072   BX065956   BX066577   BX071731   CA804617   CA804966   CA805512   CA805960   CB305214   CK605071   CK605072   CK661730   CO152750   CO152837   CO153384   CO154309   CO155924   CO156748   CO157028   CO180562   CO181818   CO183044   CO183567   CO183595   CO183634   CO184952   CO191298   CO191299   CO193220   CO193502   CO193791   CO193956   CO266266   CO269171   CO273496   CO274566   CO277462   CO280273   CO283578   CO294767   CO296701   CO302861   CO312899   CO321584   CO335588   CO335650   CO336395   CO336673   CO336793   CO338088   CO338289   CR938139   EC057636   EC074524   EC076488   EC084512   EC084787   EC085103   EC087021   EC201993   EC206168   EC213614   EC217660   EC220638   EC220845   EC224417   EC224788   EC226377   EC229148   EC231694   EC234904   EC234928   EC236457   EC244274   EC244589   EC248647   EC260895   EC261625   EC262245   EC262253   EC262331   EC262980   EC263078   EC263282   EC263455   EC263889   EC264932   EC266211   EC266297   EC266913   EC267213   EV577264   EV580566   EV581469   EV581916   EV582821   EV584199   EV584317   EV584593   EV585372   EV585525   EV587958   EV590058   EV591302   EV596471   EV597080   EV597463   EV600558   EV600655   FJ458412   GH942805   GH945626   GH946668   GH946722   GH948212   GH948657   GH949794   GH951366   GH952463   GH955095   GH957749   GH964792   GH964835   GH966549   GH970966   GH973067   GH973700   GH974442   GH974753   GH976007   GH977429   GH978060   GH978677   GH978923   GH984628   X91853 CAA62964   X91854 CAA62965   Z19052 CAA79496
UniProtKB/Swiss-Prot	Q03334
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- adult stage     (McNabb and Ashburner, 1993, Saeboe-Larssen and Lambertsson, 1996)
Additional Descriptive Data
	RpS13 transcripts are expressed at all stages of development (McNabb and Ashburner, 1993) RpS13 transcripts are abundantly expressed at all stages of development. They are three times more abundant in females than males. (Saeboe-Larssen and Lambertsson, 1996)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
ribosome inferred from direct assay (Alonso and Santaren, 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2377.55 Larval Midgut    3500 Larval Hindgut    3707.3 Larval Malpighian Tubules    4273.3 Larval Fat Body    6903.1 Larval Salivary Gland    6701.2 Larval Trachea    5724.05 Larval Carcass    4257.975 Adult Head    4053.9 Adult Eye    5162.7 Adult Brain    2434.1 Adult Thoracic-Abdominal Ganglion    3333.7 Adult Crop    5360.7 Adult Midgut    4443.6 Adult Hindgut    4377.4 Adult Malpighian Tubules    5059.8 Adult Fat Body    4881.7 Adult Salivary Gland    11214 Adult Heart    5830.8 Adult VirginFemale Spermatheca    3706.8 Adult InseminatedFemale Spermatheca    3806.7 Adult Ovary    3135.4 Adult Testis    1335 Adult Male Accessory Gland    7891.5 Adult Carcass    4870.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2377.55) Larval Midgut  (3500) Larval Hindgut  (3707.3) Larval Malpighian Tubules  (4273.3) Larval Fat Body  (6903.1) Larval Salivary Gland  (6701.2) Larval Trachea  (5724.05) Larval Carcass  (4257.975) Adult Head  (4053.9) Adult Eye  (5162.7) Adult Brain  (2434.1) Adult Thoracic-Abdominal Ganglion  (3333.7) Adult Crop  (5360.7) Adult Midgut  (4443.6) Adult Hindgut  (4377.4) Adult Malpighian Tubules  (5059.8) Adult Fat Body  (4881.7) Adult Salivary Gland  (11214) Adult Heart  (5830.8) Adult VirginFemale Spermatheca  (3706.8) Adult InseminatedFemale Spermatheca  (3806.7) Adult Ovary  (3135.4) Adult Testis  (1335) Adult Male Accessory Gland  (7891.5) Adult Carcass  (4870.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2377.55) Larval Midgut  (3500) Larval Hindgut  (3707.3) Larval Malpighian Tubules  (4273.3) Larval Fat Body  (6903.1) Larval Salivary Gland  (6701.2) Larval Trachea  (5724.05) Larval Carcass  (4257.975) Adult Head  (4053.9) Adult Eye  (5162.7) Adult Brain  (2434.1) Adult Thoracic-Abdominal Ganglion  (3333.7) Adult Crop  (5360.7) Adult Midgut  (4443.6) Adult Hindgut  (4377.4) Adult Malpighian Tubules  (5059.8) Adult Fat Body  (4881.7) Adult Salivary Gland  (11214) Adult Heart  (5830.8) Adult VirginFemale Spermatheca  (3706.8) Adult InseminatedFemale Spermatheca  (3806.7) Adult Ovary  (3135.4) Adult Testis  (1335) Adult Male Accessory Gland  (7891.5) Adult Carcass  (4870.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2377.55 Larval Midgut    3500 Larval Hindgut    3707.3 Larval Malpighian Tubules    4273.3 Larval Fat Body    6903.1 Larval Salivary Gland    6701.2 Larval Trachea    5724.05 Larval Carcass    4257.975 Adult Head    4053.9 Adult Eye    5162.7 Adult Brain    2434.1 Adult Thoracic-Abdominal Ganglion    3333.7 Adult Crop    5360.7 Adult Midgut    4443.6 Adult Hindgut    4377.4 Adult Malpighian Tubules    5059.8 Adult Fat Body    4881.7 Adult Salivary Gland    11214 Adult Heart    5830.8 Adult VirginFemale Spermatheca    3706.8 Adult InseminatedFemale Spermatheca    3806.7 Adult Ovary    3135.4 Adult Testis    1335 Adult Male Accessory Gland    7891.5 Adult Carcass    4870.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2377.55 Larval Midgut    3500 Larval Hindgut    3707.3 Larval Malpighian Tubules    4273.3 Larval Fat Body    6903.1 Larval Salivary Gland    6701.2 Larval Trachea    5724.05 Larval Carcass    4257.975 Adult Head    4053.9 Adult Eye    5162.7 Adult Brain    2434.1 Adult Thoracic-Abdominal Ganglion    3333.7 Adult Crop    5360.7 Adult Midgut    4443.6 Adult Hindgut    4377.4 Adult Malpighian Tubules    5059.8 Adult Fat Body    4881.7 Adult Salivary Gland    11214 Adult Heart    5830.8 Adult VirginFemale Spermatheca    3706.8 Adult InseminatedFemale Spermatheca    3806.7 Adult Ovary    3135.4 Adult Testis    1335 Adult Male Accessory Gland    7891.5 Adult Carcass    4870.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2377.55) Larval Midgut  (3500) Larval Hindgut  (3707.3) Larval Malpighian Tubules  (4273.3) Larval Fat Body  (6903.1) Larval Salivary Gland  (6701.2) Larval Trachea  (5724.05) Larval Carcass  (4257.975) Adult Head  (4053.9) Adult Eye  (5162.7) Adult Brain  (2434.1) Adult Thoracic-Abdominal Ganglion  (3333.7) Adult Crop  (5360.7) Adult Midgut  (4443.6) Adult Hindgut  (4377.4) Adult Malpighian Tubules  (5059.8) Adult Fat Body  (4881.7) Adult Salivary Gland  (11214) Adult Heart  (5830.8) Adult VirginFemale Spermatheca  (3706.8) Adult InseminatedFemale Spermatheca  (3806.7) Adult Ovary  (3135.4) Adult Testis  (1335) Adult Male Accessory Gland  (7891.5) Adult Carcass  (4870.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2377.55) Larval Midgut  (3500) Larval Hindgut  (3707.3) Larval Malpighian Tubules  (4273.3) Larval Fat Body  (6903.1) Larval Salivary Gland  (6701.2) Larval Trachea  (5724.05) Larval Carcass  (4257.975) Adult Head  (4053.9) Adult Eye  (5162.7) Adult Brain  (2434.1) Adult Thoracic-Abdominal Ganglion  (3333.7) Adult Crop  (5360.7) Adult Midgut  (4443.6) Adult Hindgut  (4377.4) Adult Malpighian Tubules  (5059.8) Adult Fat Body  (4881.7) Adult Salivary Gland  (11214) Adult Heart  (5830.8) Adult VirginFemale Spermatheca  (3706.8) Adult InseminatedFemale Spermatheca  (3806.7) Adult Ovary  (3135.4) Adult Testis  1335 Adult Male Accessory Gland  (7891.5) Adult Carcass  (4870.9) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2377.55 Larval Midgut    3500 Larval Hindgut    3707.3 Larval Malpighian Tubules    4273.3 Larval Fat Body    6903.1 Larval Salivary Gland    6701.2 Larval Trachea    5724.05 Larval Carcass    4257.975 Adult Head    4053.9 Adult Eye    5162.7 Adult Brain    2434.1 Adult Thoracic-Abdominal Ganglion    3333.7 Adult Crop    5360.7 Adult Midgut    4443.6 Adult Hindgut    4377.4 Adult Malpighian Tubules    5059.8 Adult Fat Body    4881.7 Adult Salivary Gland    11214 Adult Heart    5830.8 Adult VirginFemale Spermatheca    3706.8 Adult InseminatedFemale Spermatheca    3806.7 Adult Ovary    3135.4 Adult Testis    1335 Adult Male Accessory Gland    7891.5 Adult Carcass    4870.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4053.9   NA  Eye    5162.7   NA  Brain    2434.1   2377.55  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3333.7   NA  Crop    5360.7   3500  Midgut    4443.6   3707.3  Hindgut    4377.4   4273.3  Malpighian Tubules    5059.8   6903.1  Fat Body    4881.7   6701.2  Salivary Gland    11214   NA  Heart    5830.8   5724.05  Trachea    NA   NA  VirginFemale Spermatheca    3706.8   NA  InseminatedFemale Spermatheca    3806.7   NA  Ovary    3135.4   NA  Testis    1335   NA  Male Accessory Gland    7891.5   4257.975  Carcass    4870.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1404 central nervous system, larvae L3    906 central nervous system, pupae P8    440 head, virgin 1-day female    467 head, virgin 4-day female    747 head, virgin 20-day female    930 head, mated 1-day female    439 head, mated 4-day female    591 head, mated 20-day female    724 head, mated 1-day male    433 head, mated 4-day male    448 head, mated 20-day male    643 salivary gland, larvae L3 wandering    425 salivary gland, white prepupae    1005 digestive system, larvae L3 wandering    650 digestive system, 1-day adult    588 digestive system, 4-day adult    590 digestive system, 20-day adult    680 fat body, larvae L3 wandering    467 fat body, white prepupae    367 fat body, pupae P8    645 carcass, larvae L3 wandering    856 carcass, 1-day adult    424 carcass, 4-day adult    536 carcass, 20-day adult    693 ovary, virgin 4-day female    851 ovary, mated 4-day female    903 testis, mated 4-day male    353 accessory gland, mated 4-day male    538 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1404) central nervous system, larvae L3  (906) central nervous system, pupae P8  (440) head, virgin 1-day female  (467) head, virgin 4-day female  (747) head, virgin 20-day female  (930) head, mated 1-day female  (439) head, mated 4-day female  (591) head, mated 20-day female  (724) head, mated 1-day male  (433) head, mated 4-day male  (448) head, mated 20-day male  (643) salivary gland, larvae L3 wandering  (425) salivary gland, white prepupae  (1005) digestive system, larvae L3 wandering  (650) digestive system, 1-day adult  (588) digestive system, 4-day adult  (590) digestive system, 20-day adult  (680) fat body, larvae L3 wandering  (467) fat body, white prepupae  (367) fat body, pupae P8  (645) carcass, larvae L3 wandering  (856) carcass, 1-day adult  (424) carcass, 4-day adult  (536) carcass, 20-day adult  (693) ovary, virgin 4-day female  (851) ovary, mated 4-day female  (903) testis, mated 4-day male  (353) accessory gland, mated 4-day male  (538) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1404) central nervous system, larvae L3  (906) central nervous system, pupae P8  (440) head, virgin 1-day female  (467) head, virgin 4-day female  (747) head, virgin 20-day female  (930) head, mated 1-day female  (439) head, mated 4-day female  (591) head, mated 20-day female  (724) head, mated 1-day male  (433) head, mated 4-day male  (448) head, mated 20-day male  (643) salivary gland, larvae L3 wandering  (425) salivary gland, white prepupae  (1005) digestive system, larvae L3 wandering  (650) digestive system, 1-day adult  (588) digestive system, 4-day adult  (590) digestive system, 20-day adult  (680) fat body, larvae L3 wandering  (467) fat body, white prepupae  (367) fat body, pupae P8  (645) carcass, larvae L3 wandering  (856) carcass, 1-day adult  (424) carcass, 4-day adult  (536) carcass, 20-day adult  (693) ovary, virgin 4-day female  (851) ovary, mated 4-day female  (903) testis, mated 4-day male  (353) accessory gland, mated 4-day male  (538) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1404 central nervous system, larvae L3    906 central nervous system, pupae P8    440 head, virgin 1-day female    467 head, virgin 4-day female    747 head, virgin 20-day female    930 head, mated 1-day female    439 head, mated 4-day female    591 head, mated 20-day female    724 head, mated 1-day male    433 head, mated 4-day male    448 head, mated 20-day male    643 salivary gland, larvae L3 wandering    425 salivary gland, white prepupae    1005 digestive system, larvae L3 wandering    650 digestive system, 1-day adult    588 digestive system, 4-day adult    590 digestive system, 20-day adult    680 fat body, larvae L3 wandering    467 fat body, white prepupae    367 fat body, pupae P8    645 carcass, larvae L3 wandering    856 carcass, 1-day adult    424 carcass, 4-day adult    536 carcass, 20-day adult    693 ovary, virgin 4-day female    851 ovary, mated 4-day female    903 testis, mated 4-day male    353 accessory gland, mated 4-day male    538 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1404 central nervous system, larvae L3    906 central nervous system, pupae P8    440 head, virgin 1-day female    467 head, virgin 4-day female    747 head, virgin 20-day female    930 head, mated 1-day female    439 head, mated 4-day female    591 head, mated 20-day female    724 head, mated 1-day male    433 head, mated 4-day male    448 head, mated 20-day male    643 salivary gland, larvae L3 wandering    425 salivary gland, white prepupae    1005 digestive system, larvae L3 wandering    650 digestive system, 1-day adult    588 digestive system, 4-day adult    590 digestive system, 20-day adult    680 fat body, larvae L3 wandering    467 fat body, white prepupae    367 fat body, pupae P8    645 carcass, larvae L3 wandering    856 carcass, 1-day adult    424 carcass, 4-day adult    536 carcass, 20-day adult    693 ovary, virgin 4-day female    851 ovary, mated 4-day female    903 testis, mated 4-day male    353 accessory gland, mated 4-day male    538 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1404) central nervous system, larvae L3  (906) central nervous system, pupae P8  (440) head, virgin 1-day female  (467) head, virgin 4-day female  (747) head, virgin 20-day female  (930) head, mated 1-day female  (439) head, mated 4-day female  (591) head, mated 20-day female  (724) head, mated 1-day male  (433) head, mated 4-day male  (448) head, mated 20-day male  (643) salivary gland, larvae L3 wandering  (425) salivary gland, white prepupae  (1005) digestive system, larvae L3 wandering  (650) digestive system, 1-day adult  (588) digestive system, 4-day adult  (590) digestive system, 20-day adult  (680) fat body, larvae L3 wandering  (467) fat body, white prepupae  (367) fat body, pupae P8  (645) carcass, larvae L3 wandering  (856) carcass, 1-day adult  (424) carcass, 4-day adult  (536) carcass, 20-day adult  (693) ovary, virgin 4-day female  (851) ovary, mated 4-day female  (903) testis, mated 4-day male  (353) accessory gland, mated 4-day male  (538) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1404) central nervous system, larvae L3  (906) central nervous system, pupae P8  (440) head, virgin 1-day female  (467) head, virgin 4-day female  (747) head, virgin 20-day female  (930) head, mated 1-day female  (439) head, mated 4-day female  (591) head, mated 20-day female  (724) head, mated 1-day male  (433) head, mated 4-day male  (448) head, mated 20-day male  (643) salivary gland, larvae L3 wandering  (425) salivary gland, white prepupae  (1005) digestive system, larvae L3 wandering  (650) digestive system, 1-day adult  (588) digestive system, 4-day adult  (590) digestive system, 20-day adult  (680) fat body, larvae L3 wandering  (467) fat body, white prepupae  (367) fat body, pupae P8  (645) carcass, larvae L3 wandering  (856) carcass, 1-day adult  (424) carcass, 4-day adult  (536) carcass, 20-day adult  (693) ovary, virgin 4-day female  (851) ovary, mated 4-day female  (903) testis, mated 4-day male  (353) accessory gland, mated 4-day male  (538) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1404 central nervous system, larvae L3    906 central nervous system, pupae P8    440 head, virgin 1-day female    467 head, virgin 4-day female    747 head, virgin 20-day female    930 head, mated 1-day female    439 head, mated 4-day female    591 head, mated 20-day female    724 head, mated 1-day male    433 head, mated 4-day male    448 head, mated 20-day male    643 salivary gland, larvae L3 wandering    425 salivary gland, white prepupae    1005 digestive system, larvae L3 wandering    650 digestive system, 1-day adult    588 digestive system, 4-day adult    590 digestive system, 20-day adult    680 fat body, larvae L3 wandering    467 fat body, white prepupae    367 fat body, pupae P8    645 carcass, larvae L3 wandering    856 carcass, 1-day adult    424 carcass, 4-day adult    536 carcass, 20-day adult    693 ovary, virgin 4-day female    851 ovary, mated 4-day female    903 testis, mated 4-day male    353 accessory gland, mated 4-day male    538 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1742 embryo 02-04hr    2777 embryo 04-06hr    3106 embryo 06-08hr    3058 embryo 08-10hr    3248 embryo 10-12hr    3577 embryo 12-14hr    2623 embryo 14-16hr    2848 embryo 16-18hr    2629 embryo 18-20hr    2773 embryo 20-22hr    2693 embryo 22-24hr    2967 larva L1    3411 larva L2    3044 larva L3 12hr old    2016 larva L3 puffstage 1-2    1752 larva L3 puffstage 3-6    1633 larva L3 puffstage 7-9    1815 white prepupae new    1734 white prepupae 12hr    1489 white prepupae 24hr    1641 pupae 2d postWPP    1395 pupae 3d postWPP    1217 pupae 4d postWPP    1098 adult male 01day    958 adult male 05day    852 adult male 30day    1019 adult female 01day    2020 adult female 05day    2076 adult female 30day    2047 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1742) embryo 02-04hr  (2777) embryo 04-06hr  (3106) embryo 06-08hr  (3058) embryo 08-10hr  (3248) embryo 10-12hr  (3577) embryo 12-14hr  (2623) embryo 14-16hr  (2848) embryo 16-18hr  (2629) embryo 18-20hr  (2773) embryo 20-22hr  (2693) embryo 22-24hr  (2967) larva L1  (3411) larva L2  (3044) larva L3 12hr old  (2016) larva L3 puffstage 1-2  (1752) larva L3 puffstage 3-6  (1633) larva L3 puffstage 7-9  (1815) white prepupae new  (1734) white prepupae 12hr  (1489) white prepupae 24hr  (1641) pupae 2d postWPP  (1395) pupae 3d postWPP  (1217) pupae 4d postWPP  (1098) adult male 01day  (958) adult male 05day  (852) adult male 30day  (1019) adult female 01day  (2020) adult female 05day  (2076) adult female 30day  (2047) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1742) embryo 02-04hr  (2777) embryo 04-06hr  (3106) embryo 06-08hr  (3058) embryo 08-10hr  (3248) embryo 10-12hr  (3577) embryo 12-14hr  (2623) embryo 14-16hr  (2848) embryo 16-18hr  (2629) embryo 18-20hr  (2773) embryo 20-22hr  (2693) embryo 22-24hr  (2967) larva L1  (3411) larva L2  (3044) larva L3 12hr old  (2016) larva L3 puffstage 1-2  (1752) larva L3 puffstage 3-6  (1633) larva L3 puffstage 7-9  (1815) white prepupae new  (1734) white prepupae 12hr  (1489) white prepupae 24hr  (1641) pupae 2d postWPP  (1395) pupae 3d postWPP  (1217) pupae 4d postWPP  (1098) adult male 01day  (958) adult male 05day  (852) adult male 30day  (1019) adult female 01day  (2020) adult female 05day  (2076) adult female 30day  (2047) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1742 embryo 02-04hr    2777 embryo 04-06hr    3106 embryo 06-08hr    3058 embryo 08-10hr    3248 embryo 10-12hr    3577 embryo 12-14hr    2623 embryo 14-16hr    2848 embryo 16-18hr    2629 embryo 18-20hr    2773 embryo 20-22hr    2693 embryo 22-24hr    2967 larva L1    3411 larva L2    3044 larva L3 12hr old    2016 larva L3 puffstage 1-2    1752 larva L3 puffstage 3-6    1633 larva L3 puffstage 7-9    1815 white prepupae new    1734 white prepupae 12hr    1489 white prepupae 24hr    1641 pupae 2d postWPP    1395 pupae 3d postWPP    1217 pupae 4d postWPP    1098 adult male 01day    958 adult male 05day    852 adult male 30day    1019 adult female 01day    2020 adult female 05day    2076 adult female 30day    2047 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1742 embryo 02-04hr    2777 embryo 04-06hr    3106 embryo 06-08hr    3058 embryo 08-10hr    3248 embryo 10-12hr    3577 embryo 12-14hr    2623 embryo 14-16hr    2848 embryo 16-18hr    2629 embryo 18-20hr    2773 embryo 20-22hr    2693 embryo 22-24hr    2967 larva L1    3411 larva L2    3044 larva L3 12hr old    2016 larva L3 puffstage 1-2    1752 larva L3 puffstage 3-6    1633 larva L3 puffstage 7-9    1815 white prepupae new    1734 white prepupae 12hr    1489 white prepupae 24hr    1641 pupae 2d postWPP    1395 pupae 3d postWPP    1217 pupae 4d postWPP    1098 adult male 01day    958 adult male 05day    852 adult male 30day    1019 adult female 01day    2020 adult female 05day    2076 adult female 30day    2047 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1742) embryo 02-04hr  (2777) embryo 04-06hr  (3106) embryo 06-08hr  (3058) embryo 08-10hr  (3248) embryo 10-12hr  (3577) embryo 12-14hr  (2623) embryo 14-16hr  (2848) embryo 16-18hr  (2629) embryo 18-20hr  (2773) embryo 20-22hr  (2693) embryo 22-24hr  (2967) larva L1  (3411) larva L2  (3044) larva L3 12hr old  (2016) larva L3 puffstage 1-2  (1752) larva L3 puffstage 3-6  (1633) larva L3 puffstage 7-9  (1815) white prepupae new  (1734) white prepupae 12hr  (1489) white prepupae 24hr  (1641) pupae 2d postWPP  (1395) pupae 3d postWPP  (1217) pupae 4d postWPP  (1098) adult male 01day  (958) adult male 05day  (852) adult male 30day  (1019) adult female 01day  (2020) adult female 05day  (2076) adult female 30day  (2047) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1742) embryo 02-04hr  (2777) embryo 04-06hr  (3106) embryo 06-08hr  (3058) embryo 08-10hr  (3248) embryo 10-12hr  (3577) embryo 12-14hr  (2623) embryo 14-16hr  (2848) embryo 16-18hr  (2629) embryo 18-20hr  (2773) embryo 20-22hr  (2693) embryo 22-24hr  (2967) larva L1  (3411) larva L2  (3044) larva L3 12hr old  (2016) larva L3 puffstage 1-2  (1752) larva L3 puffstage 3-6  (1633) larva L3 puffstage 7-9  (1815) white prepupae new  (1734) white prepupae 12hr  (1489) white prepupae 24hr  (1641) pupae 2d postWPP  (1395) pupae 3d postWPP  (1217) pupae 4d postWPP  (1098) adult male 01day  (958) adult male 05day  (852) adult male 30day  (1019) adult female 01day  (2020) adult female 05day  (2076) adult female 30day  (2047) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1742 embryo 02-04hr    2777 embryo 04-06hr    3106 embryo 06-08hr    3058 embryo 08-10hr    3248 embryo 10-12hr    3577 embryo 12-14hr    2623 embryo 14-16hr    2848 embryo 16-18hr    2629 embryo 18-20hr    2773 embryo 20-22hr    2693 embryo 22-24hr    2967 larva L1    3411 larva L2    3044 larva L3 12hr old    2016 larva L3 puffstage 1-2    1752 larva L3 puffstage 3-6    1633 larva L3 puffstage 7-9    1815 white prepupae new    1734 white prepupae 12hr    1489 white prepupae 24hr    1641 pupae 2d postWPP    1395 pupae 3d postWPP    1217 pupae 4d postWPP    1098 adult male 01day    958 adult male 05day    852 adult male 30day    1019 adult female 01day    2020 adult female 05day    2076 adult female 30day    2047 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2387 Schneider line 2 Sg4    1519 embryonic 1182-4H    1906 embryonic GM2    776 embryonic Kc167    901 embryonic S1    2095 embryonic S3    1062 leg disc CME L1    2141 wing disc CME-W2    1321 wing disc ML-DmD8    2284 wing disc ML-DmD9    2385 wing disc ML-DmD16-c3    2536 wing disc ML-DmD21    3574 wing disc ML-DmD32    1925 haltere disc ML-DmD17-c3    1771 eye-antennal disc ML-DmD11    3164 antennal disc ML-DmD20-c5    2175 mixed discs ML-DmD4-c1    1885 CNS ML-DmBG1-c1    2195 CNS ML-DmBG2-c2    1183 tumorous blood cells mbn2    875 ovary fGS/OSS    791 ovary OSC    705 ovary OSS    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2387) Schneider line 2 Sg4  (1519) embryonic 1182-4H  (1906) embryonic GM2  (776) embryonic Kc167  (901) embryonic S1  (2095) embryonic S3  (1062) leg disc CME L1  (2141) wing disc CME-W2  (1321) wing disc ML-DmD8  (2284) wing disc ML-DmD9  (2385) wing disc ML-DmD16-c3  (2536) wing disc ML-DmD21  (3574) wing disc ML-DmD32  (1925) haltere disc ML-DmD17-c3  (1771) eye-antennal disc ML-DmD11  (3164) antennal disc ML-DmD20-c5  (2175) mixed discs ML-DmD4-c1  (1885) CNS ML-DmBG1-c1  (2195) CNS ML-DmBG2-c2  (1183) tumorous blood cells mbn2  (875) ovary fGS/OSS  (791) ovary OSC  (705) ovary OSS  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2387) Schneider line 2 Sg4  (1519) embryonic 1182-4H  (1906) embryonic GM2  (776) embryonic Kc167  (901) embryonic S1  (2095) embryonic S3  (1062) leg disc CME L1  (2141) wing disc CME-W2  (1321) wing disc ML-DmD8  (2284) wing disc ML-DmD9  (2385) wing disc ML-DmD16-c3  (2536) wing disc ML-DmD21  (3574) wing disc ML-DmD32  (1925) haltere disc ML-DmD17-c3  (1771) eye-antennal disc ML-DmD11  (3164) antennal disc ML-DmD20-c5  (2175) mixed discs ML-DmD4-c1  (1885) CNS ML-DmBG1-c1  (2195) CNS ML-DmBG2-c2  (1183) tumorous blood cells mbn2  (875) ovary fGS/OSS  (791) ovary OSC  (705) ovary OSS  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2387 Schneider line 2 Sg4    1519 embryonic 1182-4H    1906 embryonic GM2    776 embryonic Kc167    901 embryonic S1    2095 embryonic S3    1062 leg disc CME L1    2141 wing disc CME-W2    1321 wing disc ML-DmD8    2284 wing disc ML-DmD9    2385 wing disc ML-DmD16-c3    2536 wing disc ML-DmD21    3574 wing disc ML-DmD32    1925 haltere disc ML-DmD17-c3    1771 eye-antennal disc ML-DmD11    3164 antennal disc ML-DmD20-c5    2175 mixed discs ML-DmD4-c1    1885 CNS ML-DmBG1-c1    2195 CNS ML-DmBG2-c2    1183 tumorous blood cells mbn2    875 ovary fGS/OSS    791 ovary OSC    705 ovary OSS    392 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2387 Schneider line 2 Sg4    1519 embryonic 1182-4H    1906 embryonic GM2    776 embryonic Kc167    901 embryonic S1    2095 embryonic S3    1062 leg disc CME L1    2141 wing disc CME-W2    1321 wing disc ML-DmD8    2284 wing disc ML-DmD9    2385 wing disc ML-DmD16-c3    2536 wing disc ML-DmD21    3574 wing disc ML-DmD32    1925 haltere disc ML-DmD17-c3    1771 eye-antennal disc ML-DmD11    3164 antennal disc ML-DmD20-c5    2175 mixed discs ML-DmD4-c1    1885 CNS ML-DmBG1-c1    2195 CNS ML-DmBG2-c2    1183 tumorous blood cells mbn2    875 ovary fGS/OSS    791 ovary OSC    705 ovary OSS    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (2387) Schneider line 2 Sg4  (1519) embryonic 1182-4H  (1906) embryonic GM2  (776) embryonic Kc167  (901) embryonic S1  (2095) embryonic S3  (1062) leg disc CME L1  (2141) wing disc CME-W2  (1321) wing disc ML-DmD8  (2284) wing disc ML-DmD9  (2385) wing disc ML-DmD16-c3  (2536) wing disc ML-DmD21  (3574) wing disc ML-DmD32  (1925) haltere disc ML-DmD17-c3  (1771) eye-antennal disc ML-DmD11  (3164) antennal disc ML-DmD20-c5  (2175) mixed discs ML-DmD4-c1  (1885) CNS ML-DmBG1-c1  (2195) CNS ML-DmBG2-c2  (1183) tumorous blood cells mbn2  (875) ovary fGS/OSS  (791) ovary OSC  (705) ovary OSS  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (2387) Schneider line 2 Sg4  (1519) embryonic 1182-4H  (1906) embryonic GM2  (776) embryonic Kc167  (901) embryonic S1  (2095) embryonic S3  (1062) leg disc CME L1  (2141) wing disc CME-W2  (1321) wing disc ML-DmD8  (2284) wing disc ML-DmD9  (2385) wing disc ML-DmD16-c3  (2536) wing disc ML-DmD21  (3574) wing disc ML-DmD32  (1925) haltere disc ML-DmD17-c3  (1771) eye-antennal disc ML-DmD11  (3164) antennal disc ML-DmD20-c5  (2175) mixed discs ML-DmD4-c1  (1885) CNS ML-DmBG1-c1  (2195) CNS ML-DmBG2-c2  (1183) tumorous blood cells mbn2  (875) ovary fGS/OSS  (791) ovary OSC  (705) ovary OSS  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2387 Schneider line 2 Sg4    1519 embryonic 1182-4H    1906 embryonic GM2    776 embryonic Kc167    901 embryonic S1    2095 embryonic S3    1062 leg disc CME L1    2141 wing disc CME-W2    1321 wing disc ML-DmD8    2284 wing disc ML-DmD9    2385 wing disc ML-DmD16-c3    2536 wing disc ML-DmD21    3574 wing disc ML-DmD32    1925 haltere disc ML-DmD17-c3    1771 eye-antennal disc ML-DmD11    3164 antennal disc ML-DmD20-c5    2175 mixed discs ML-DmD4-c1    1885 CNS ML-DmBG1-c1    2195 CNS ML-DmBG2-c2    1183 tumorous blood cells mbn2    875 ovary fGS/OSS    791 ovary OSC    705 ovary OSS    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    706 cold shock, 4-day adult    557 heat shock, 4-day adult    1222 Cadmium 50 mM 6 hrs, larvae L3    1081 Cadmium 50 mM 12 hrs, larvae L3    1133 Cadmium 50 mM 48 hrs, 4-day adult    984 Cadmium 100 mM 48 hrs, 4-day adult    785 Copper 0.5 mM 12 hrs, larvae L3    772 Copper 15 mM 48 hrs, 4-day adult    274 Zinc 5 mM 12 hrs, larvae L3    619 Zinc 4.5 mM 48 hrs, 4-day adult    404 Ethanol 2.5% 3 hrs, larvae L3    1293 Ethanol 5% 3 hrs, larvae L3    958 Ethanol 10% 3 hrs, larvae L3    1154 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1072 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    942 Caffeine 25 mg/ml 48 hrs, 4-day adult    558 Paraquat 5 mM 48 hrs, 4-day adult    1025 Paraquat 10 mM 48 hrs, 4-day adult    1277 Rotenone 2 μg 12 hrs, larvae L3    1049 Rotenone 8 μg 12 hrs, larvae L3    1274 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (706) cold shock, 4-day adult  (557) heat shock, 4-day adult  (1222) Cadmium 50 mM 6 hrs, larvae L3  (1081) Cadmium 50 mM 12 hrs, larvae L3  (1133) Cadmium 50 mM 48 hrs, 4-day adult  (984) Cadmium 100 mM 48 hrs, 4-day adult  (785) Copper 0.5 mM 12 hrs, larvae L3  (772) Copper 15 mM 48 hrs, 4-day adult  (274) Zinc 5 mM 12 hrs, larvae L3  (619) Zinc 4.5 mM 48 hrs, 4-day adult  (404) Ethanol 2.5% 3 hrs, larvae L3  (1293) Ethanol 5% 3 hrs, larvae L3  (958) Ethanol 10% 3 hrs, larvae L3  (1154) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1072) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (942) Caffeine 25 mg/ml 48 hrs, 4-day adult  (558) Paraquat 5 mM 48 hrs, 4-day adult  (1025) Paraquat 10 mM 48 hrs, 4-day adult  (1277) Rotenone 2 μg 12 hrs, larvae L3  (1049) Rotenone 8 μg 12 hrs, larvae L3  (1274) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (706) cold shock, 4-day adult  (557) heat shock, 4-day adult  (1222) Cadmium 50 mM 6 hrs, larvae L3  (1081) Cadmium 50 mM 12 hrs, larvae L3  (1133) Cadmium 50 mM 48 hrs, 4-day adult  (984) Cadmium 100 mM 48 hrs, 4-day adult  (785) Copper 0.5 mM 12 hrs, larvae L3  (772) Copper 15 mM 48 hrs, 4-day adult  (274) Zinc 5 mM 12 hrs, larvae L3  (619) Zinc 4.5 mM 48 hrs, 4-day adult  (404) Ethanol 2.5% 3 hrs, larvae L3  (1293) Ethanol 5% 3 hrs, larvae L3  (958) Ethanol 10% 3 hrs, larvae L3  (1154) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1072) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (942) Caffeine 25 mg/ml 48 hrs, 4-day adult  (558) Paraquat 5 mM 48 hrs, 4-day adult  (1025) Paraquat 10 mM 48 hrs, 4-day adult  (1277) Rotenone 2 μg 12 hrs, larvae L3  (1049) Rotenone 8 μg 12 hrs, larvae L3  (1274) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    706 cold shock, 4-day adult    557 heat shock, 4-day adult    1222 Cadmium 50 mM 6 hrs, larvae L3    1081 Cadmium 50 mM 12 hrs, larvae L3    1133 Cadmium 50 mM 48 hrs, 4-day adult    984 Cadmium 100 mM 48 hrs, 4-day adult    785 Copper 0.5 mM 12 hrs, larvae L3    772 Copper 15 mM 48 hrs, 4-day adult    274 Zinc 5 mM 12 hrs, larvae L3    619 Zinc 4.5 mM 48 hrs, 4-day adult    404 Ethanol 2.5% 3 hrs, larvae L3    1293 Ethanol 5% 3 hrs, larvae L3    958 Ethanol 10% 3 hrs, larvae L3    1154 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1072 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    942 Caffeine 25 mg/ml 48 hrs, 4-day adult    558 Paraquat 5 mM 48 hrs, 4-day adult    1025 Paraquat 10 mM 48 hrs, 4-day adult    1277 Rotenone 2 μg 12 hrs, larvae L3    1049 Rotenone 8 μg 12 hrs, larvae L3    1274 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    706 cold shock, 4-day adult    557 heat shock, 4-day adult    1222 Cadmium 50 mM 6 hrs, larvae L3    1081 Cadmium 50 mM 12 hrs, larvae L3    1133 Cadmium 50 mM 48 hrs, 4-day adult    984 Cadmium 100 mM 48 hrs, 4-day adult    785 Copper 0.5 mM 12 hrs, larvae L3    772 Copper 15 mM 48 hrs, 4-day adult    274 Zinc 5 mM 12 hrs, larvae L3    619 Zinc 4.5 mM 48 hrs, 4-day adult    404 Ethanol 2.5% 3 hrs, larvae L3    1293 Ethanol 5% 3 hrs, larvae L3    958 Ethanol 10% 3 hrs, larvae L3    1154 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1072 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    942 Caffeine 25 mg/ml 48 hrs, 4-day adult    558 Paraquat 5 mM 48 hrs, 4-day adult    1025 Paraquat 10 mM 48 hrs, 4-day adult    1277 Rotenone 2 μg 12 hrs, larvae L3    1049 Rotenone 8 μg 12 hrs, larvae L3    1274 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (706) cold shock, 4-day adult  (557) heat shock, 4-day adult  (1222) Cadmium 50 mM 6 hrs, larvae L3  (1081) Cadmium 50 mM 12 hrs, larvae L3  (1133) Cadmium 50 mM 48 hrs, 4-day adult  (984) Cadmium 100 mM 48 hrs, 4-day adult  (785) Copper 0.5 mM 12 hrs, larvae L3  (772) Copper 15 mM 48 hrs, 4-day adult  (274) Zinc 5 mM 12 hrs, larvae L3  (619) Zinc 4.5 mM 48 hrs, 4-day adult  (404) Ethanol 2.5% 3 hrs, larvae L3  (1293) Ethanol 5% 3 hrs, larvae L3  (958) Ethanol 10% 3 hrs, larvae L3  (1154) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1072) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (942) Caffeine 25 mg/ml 48 hrs, 4-day adult  (558) Paraquat 5 mM 48 hrs, 4-day adult  (1025) Paraquat 10 mM 48 hrs, 4-day adult  (1277) Rotenone 2 μg 12 hrs, larvae L3  (1049) Rotenone 8 μg 12 hrs, larvae L3  (1274) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (706) cold shock, 4-day adult  (557) heat shock, 4-day adult  (1222) Cadmium 50 mM 6 hrs, larvae L3  (1081) Cadmium 50 mM 12 hrs, larvae L3  (1133) Cadmium 50 mM 48 hrs, 4-day adult  (984) Cadmium 100 mM 48 hrs, 4-day adult  (785) Copper 0.5 mM 12 hrs, larvae L3  (772) Copper 15 mM 48 hrs, 4-day adult  (274) Zinc 5 mM 12 hrs, larvae L3  (619) Zinc 4.5 mM 48 hrs, 4-day adult  (404) Ethanol 2.5% 3 hrs, larvae L3  (1293) Ethanol 5% 3 hrs, larvae L3  (958) Ethanol 10% 3 hrs, larvae L3  (1154) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (1072) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (942) Caffeine 25 mg/ml 48 hrs, 4-day adult  (558) Paraquat 5 mM 48 hrs, 4-day adult  (1025) Paraquat 10 mM 48 hrs, 4-day adult  (1277) Rotenone 2 μg 12 hrs, larvae L3  (1049) Rotenone 8 μg 12 hrs, larvae L3  (1274) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    706 cold shock, 4-day adult    557 heat shock, 4-day adult    1222 Cadmium 50 mM 6 hrs, larvae L3    1081 Cadmium 50 mM 12 hrs, larvae L3    1133 Cadmium 50 mM 48 hrs, 4-day adult    984 Cadmium 100 mM 48 hrs, 4-day adult    785 Copper 0.5 mM 12 hrs, larvae L3    772 Copper 15 mM 48 hrs, 4-day adult    274 Zinc 5 mM 12 hrs, larvae L3    619 Zinc 4.5 mM 48 hrs, 4-day adult    404 Ethanol 2.5% 3 hrs, larvae L3    1293 Ethanol 5% 3 hrs, larvae L3    958 Ethanol 10% 3 hrs, larvae L3    1154 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1072 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    942 Caffeine 25 mg/ml 48 hrs, 4-day adult    558 Paraquat 5 mM 48 hrs, 4-day adult    1025 Paraquat 10 mM 48 hrs, 4-day adult    1277 Rotenone 2 μg 12 hrs, larvae L3    1049 Rotenone 8 μg 12 hrs, larvae L3    1274 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • LD23958 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010265 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13389-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 RpS13GD8007 lethal | recessive RpS131 RpS13k09614 RpS13k15708 Other Phenotypes Allele developmental rate defective, with Scer\GAL4amn-c651 RpS13dsRNA.WIZ.Scer\UAS Minute RpS131 Minute | dominant RpS131 size defective | adult stage RpS131 visible RpS131 visible | dominant RpS13unspecified Phenotype manifest in Allele adult heart RpS131 macrochaeta RpS131 RpS13unspecified prothoracic gland, with Scer\GAL4amn-c651 RpS13dsRNA.WIZ.Scer\UAS scutellar bristle RpS131
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of RpS13 Class Mutagen Stocks Known lesion RpS13k09614 P-element activity 2 -- RpS131 loss of function allele P-element activity 1 Yes RpS13G8009 P-element activity 1 -- RpS13k15708 P-element activity 0 -- RpS13unspecified 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpS13 Class Mutagen Stocks Known lesion RpS13GD8007 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS13HMS00135 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS13KK109083 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS13dsRNA.cLa in vitro construct - RNAi 0 Yes RpS13dsRNA.WIZ.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(2L)J2 (Saeboe-Larssen and Lambertsson, 1996) Df(2L)J27 (Saeboe-Larssen and Lambertsson, 1996) Df(2L)N22-5 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)N22-14 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)Prl (Saeboe-Larssen and Lambertsson, 1996) Df(2L)TE29Aa-11 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)TE29Aa-14 (BDGP Project Members, 1994-1999)
Disrupted in	Df(2L)dph27 (Saeboe-Larssen and Lambertsson, 1996) Df(2L)prd2.27 (Saeboe-Larssen and Lambertsson, 1996)
Duplicated in	Dp(2;3)dph27 (Saeboe-Larssen and Lambertsson, 1996) Dp(2;3)prd2.27 (Saeboe-Larssen and Lambertsson, 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8007} NA P{KK109083} NA P{TRiP.HMS00135} NA P{UAS-RpS13.RNAi} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}RpS131 No P{lacW}RpS13k09614 No P{lacW}RpS13k15708 No insertion of mobile activating element P{EP}EP646EP646 NA P{EP}EP2188 NA P{EP}EP2517 NA P{EP}EP2534 NA P{EP}RpS13G8009 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from direct assay (Alonso and Santaren, 2006)
Biological Process
CV term Evidence References
mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component
CV term Evidence References
ribosome inferred from direct assay (Alonso and Santaren, 2006)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from sequence or structural similarity with Saccharomyces RPS13 (FlyBase, 1992-) non-traceable author statement (Ashburner, 1992.12.9, Swiss-Prot Project Members, 1993.10.1)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with Saccharomyces RPS13 (FlyBase, 1992-) non-traceable author statement (Ashburner, 1992.12.9)
Cellular Component
CV term Evidence References
cytosolic small ribosomal subunit inferred from sequence or structural similarity with Saccharomyces RPS13 (FlyBase, 1992-) non-traceable author statement (Ashburner, 1992.12.9) ribosome non-traceable author statement (Swiss-Prot Project Members, 1993.10.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpS13 allele Gene References unspecified Pi3K92E (Coelho et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60275 DroID - A comprehensive database of gene and protein interactions. • FBgn0010265 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34149
Orthologs
OrthoDB Orthologs (48) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG67H69J Dipteran inclusive ortholog search EOG6MGSHQ Insect inclusive ortholog search EOG6VHJ3X Arthropod inclusive ortholog search EOG69GJ03 Metazoa inclusive ortholog search EOG69SK2C
Orthologs in Drosophila Species (EOG67H69J)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpS13     Drosophila simulans   Dsim\GD22414 Y   Drosophila sechellia   Dsec\GM13013 Y   Drosophila erecta   Dere\GG23452 Y   Drosophila yakuba   Dyak\RpS13 Y   Drosophila ananassae   Dana\GF14686 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA12248 Y   Drosophila persimilis   Dper\GL18905 Y   Drosophila willistoni   Dwil\GK13532 Y   Drosophila virilis   Dvir\GJ11538 Y   Drosophila virilis   Dvir\GJ23232     Drosophila mojavensis   Dmoj\GI13008 Y   Drosophila mojavensis   Dmoj\GI23672     Drosophila grimshawi   Dgri\GH14648     Drosophila grimshawi   Dgri\GH10885 Y
Orthologs in non-Drosophila Dipterans (EOG6MGSHQ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\40sRpS13   Anopheles gambiae Malaria mosquito  Agam\RpS13   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015099
Orthologs in non-Dipteran Insects (EOG6VHJ3X)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RpS13   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016505   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12469   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12470   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12463   Atta cephalotes Leafcutter ant  Acep\ACEP14466   Atta cephalotes Leafcutter ant  Acep\ACEP14449   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16641   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23566   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15353   Linepithema humile Argentine ant  Lhum\LH20308   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23259   Solenopsis invicta Red fire ant  Sinv\SINV16701   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008671   Bombyx mori Silkmoth  Bmor\RpS13   Pediculus humanus Human body louse  Phum\PHUM357760   Tribolium castaneum Red flour beetle  Tcas\TC004990   Tribolium castaneum Red flour beetle  Tcas\TC011123
Orthologs in non-Insect Arthropods (EOG69GJ03)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_308825
Orthologs in non-Arthropod Metazoa (EOG69SK2C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rps-13   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022161gn   Danio rerio Zebrafish  Drer\rps13   Xenopus tropicalis Western clawed frog  Xtro\rps13   Gallus gallus Domestic chicken  Ggal\RPS13   Mus musculus House mouse  Mmus\Rps13   Mus musculus House mouse  Mmus\Rps13   Mus musculus House mouse  Mmus\Rps13   Rattus norvegicus Norway rat  Rnor\Rps13   Rattus norvegicus Norway rat  Rnor\Rps13   Homo sapiens Human  Hsap\ENSG00000110700
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000110700
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22414 Drosophila sechellia Dsec\GM13013 Drosophila erecta Dere\GG23452 Drosophila yakuba Dyak\RpS13 Drosophila ananassae Dana\GF14686 Drosophila pseudoobscura pseudoobscura Dpse\GA12248 Drosophila persimilis Dper\GL18905 Drosophila willistoni Dwil\GK13532 Drosophila virilis Dvir\GJ11538 Drosophila mojavensis Dmoj\GI13008 Drosophila grimshawi Dgri\GH10885
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	33275 w1118; P{EP}RpS13G8009/SM6a 2246 y1 w*; P{lacW}RpS131/CyO 34820 y1 sc* v1; P{TRiP.HMS00135}attP2 10910 y1 w67c23; P{lacW}RpS13k09614/CyO
Kyoto	102720 y1 w67c23 ; P{lacW}RpS13k09614 / CyO
VDRC	v105496 P{KK109083}VIE-260B v17168 w1118; P{GD8007}v17168
Genomic Clones ( 1 )
	BACR15P08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 367 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD23958
Other clones	yak-ad_RpS13 yak-em_RpS13
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT25206 AT26338 GH04405 GH04789 GH04953 GH06925 GH08177 GH11252 GH13830 GH14169 GH19768 GH20212 GH21594 GH24249 GH24384 GH24428 GH26966 GM01063 GM01171 GM08610 GM12239 GM15473 GM16121 GM16687 GM17019 GM18154 GM18782 GM18784 GM20510 GM21269 GM24219 GM25343 GM27905 GM29741 GM31287 GM32373 LD07044 LD15696 LD29069 LD29350 LP03875 LP04203 LP05084 LP07949 LP09772 LP10648 LP11047 LP11101 LP21401 RE04360 RE05295 RE06516 RE07317 RE07807 RE09929 RE10940 RE11682 RE11918 RE13082 RE16087 RE16116 RE17343 RE17711 RE20218 RE21864 RE23824 RE26427 RE28501 RE29280 RE29308 RE30262 RE30527 RE31060 RE31406 RE31664 RE35524 RE35765 RE36737 RE37779 RE39918 RE41362 RE44161 RE45159 RE46188 RE46330 RE47119 RE47749 RE52450 RE54586 RE56052 RE60362 RE60431 RE61292 RE63580 RE67841 RE70814 RE70864 RE72296 RE73813 RE73983 RE74665 RE74845 RH03290 RH15973 RH17282 RH31383 RH39509 RH43326 RH44304 RH46441 RH50508 RH50792 RH52495 RH52534 RH61943 RH64739 RH69633 RH72973 RH74329 SD11301 SD11393 SD11408 SD11420 SD12344 SD12771 SD12858 SD13016 SD14255 SD14394 SD14667 SD15675 SD16219 SD16287 SD17657 SD18138 SD18721 SD20638 SD21566 SD22311 SD22613 SD23449 SD23506 SD23523 SD25072 SD25445 SD25954 SD26028 SD26051 SD26331 SD26625 SD26652 SD26768 SD27339 SD27491 SD28123
Other clones	6162 11159 19952 30199 35966 40430 46057 61162 61517 62491 76038 78464 81213 84252 97358 102177 105211 108588 147531 473704 522349 522709 524998 525722 528199 533579 542519 542584 557813 558107 561851 569893 569937 571235 CK01.13C.G1 CK01.22B.F3 CK01.36B.H10 CK01.123A.F8 Dmel_dig_004349_0605_3648 Dmel_dig_006277_0668_3557 Dmel_dig_006614_0607_1942 Dmel_dig_006748_0601_1513 Dmel_dig_009157_0704_2753 Dmel_dig_009601_0636_0460 Dmel_dig_009851_0672_2362 Dmel_dig_009982_0642_1535 Dmel_dig_011486_0653_1135 Dmel_dig_014093_0700_3004 Dmel_neb_006579_0333_3674 Dmel_neb_008590_0854_0591 Dmel_neb_010830_0927_0351 Dmel_neb_013606_0443_2555 Dmel_neb_014185_0198_1099 Dmel_neb_014339_0872_1779 Dmel_neb_014735_0879_1248 Dmel_neb_014855_0822_3475 EC02055 EC15041 EC24467 EC25970 EC26011 EC26069 EC28879 EC30655 EC30656 EC35313 EC36246 EC36813 EC37151 EK093756 EK111152 EK114503 EK124744 EK145816 EK153547 EK163709 EK185041 EK185954 EK207626 EK214659 EK230522 EN00344 EN00550 EN01851 EN03906 EN07020 EN09030 EN09764 EN10760 EN10916 EN12440 EN13016 EN13241 EN15928 EN16415 ESG0114b.B21_H10 ESG0115d.B21_H07 ESG0118c.B21_B08 ESG0120c.B21_A03 FGA006C05 FGA010E01 FGA011D05 FGC001G05 FGC003B01 FGC007G05 FGC010B11 FGC010F03 FGC014F09 FGC016B06 FGC021C02 FGC021D06 FGC022D11 FGC024A09 FGC024B01 FGC024B09 FGC025G10 FGC026A08 FGC027A07 FGC028A05 FGC028D03 FGC028H06 FGC030F02 FGC032D08 FGC032G05 FGC033E06 FGH001G03 FGH101B05 FGH102E02 FGH104C06 FGH104D10 FGH109E09 FGH112A09 FGH113A11 FGH113H12 FGH122G12 FGH123A02 FGH127C08 FGH128G11 FGH129F07 FGM001A09 FGM001B08 FGM002G10 FGM004H10 FGM101D10 FGM104H06 FGM105E07 FGM211A01 FGM212G04 FGM216B05 FGM216G10 FGM220F05 FGM221F06 FGM222F07 FGM225B08 FGM231H11 FGM232G12 FGM233A03 FGM233F07 FGM234C11 FGM234D10 FGM236E04 FGM237D12 FGM237E05 FGM305B01 FGM306C12 FGM307E09 FGM309G10 GH06825 GM20685 Nfly-029 RE01481 RE22984 RE64985 RE67809 RE74466 RH02170 RH15247 RH43188 RH52494 RH60020 RH64625 RH74551 RP004050972 RP004103436 RP004143955 RP004157693 RP004179234 RP004196281 RP004196959 RP004199129 RP004217552 RP004217649 RP004228578 RP004253936 RP004255288 RP004257298 RP004264792 RP004291791 RP004329171 RP004357158 RP004363945 RP004377379 RP004388028 RP004419386 RP004478991 RP004499093 RP004499127 SD12796 UT01656
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010265 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34149
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: RpS13 l(2)k09614 (Spradling et al., 1999)
Additional comments
Other Comments
	Haploinsufficient locus. (Cook et al., 2012) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Minute gene. (Marygold et al., 2007) Deletions removing RpS13 but no other cytoplasmic ribosomal protein-encoding genes show Minute phenotypes. (Marygold et al., 2007) Molecularly-defined mutations in RpS13 result in Minute phenotypes. (Marygold et al., 2007) Expression is enriched in embryonic gonads. (Shigenobu et al., 2006) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) cDNA for ribosomal protein S13 isolated. (McNabb and Ashburner, 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057590 NM_001038796 RefSeq (Proteins) • NP_476938 NP_001033885 DDBJ / EMBL / GenBank • AA820377 AAF52649 AAF52649.1 AAL13765 ABC65883 AC004281 AC005555 AC092220 AI455407 AQ025899 AY058536 CAA62964 CAA62965 CAA79496 X91853 X91854 Z19052 Entrez Gene - A searchable database of RefSeq genes. • 34149 UniProtKB/Swiss-Prot • Q03334
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S15 (IPR000589) S15/NS1, RNA-binding (IPR009068) Ribosomal protein S13/S15, N-terminal (IPR012606) Ribosomal protein S15P (IPR023029) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD23958
Linkouts
	BioGRID - A database of protein and genetic interactions • 60275 DroID - A comprehensive database of gene and protein interactions. • FBgn0010265 DRSC - Results from RNAi screens. • FBgn0010265 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010265 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13389-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010265 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34149 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34149 modMine - Data generated by the modENCODE project. • FBgn0010265
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	CG13389 (Cermelli et al., 2006, Goshima et al., 2007, Keleman et al., 2009.8.5, Marygold et al., 2007, Piacentini et al., 2009, Ni et al., 2011.7.19, Cammarato et al., 2011) l(2)k09614 (BDGP Project Members, 1994-1999, ) M(2)29B (Marygold et al., 2007) M(2)32 (Lambertsson et al., 1994) M(2)32A (Grewal et al., 2005, Montagne et al., 1999, Saeboe-Larssen and Lambertsson, 1996, ) Rp17   RpS13 (Cermelli et al., 2006, Shigenobu et al., 2006, Oren-Giladi et al., 2008, Goshima et al., 2007, Andersen and Leevers, 2007, Kallappagoudar et al., 2010, Stieper et al., 2008, Nie et al., 2009, Marygold et al., 2007, Zhou et al., 2008, Lin et al., 2011, Casad et al., 2011, Cook et al., 2012) RPS13 (Pinnola et al., 2007) Rp S13 (Alonso and Santaren, 2006) S13 (Molnar et al., 2003)
Name Synonym	Minute(2)32A (Saeboe-Larsson, 1995.9.26, Saeboe-Larsson, 1995.9.26) Ribosomal protein S13 (Cammarato et al., 2011) ribosomal protein S17 (Ashburner, 1992.12.9)
Secondary FlyBase IDs
	FBgn0021990
References ( 55 )
Generate a list of	All references relating to this gene ( 55 )
List References by type	Research paper  ( 29 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 9 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 3 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 4 )
	Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Casad et al., 2011, Genetics 189(3): 861--870 Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency in Drosophila melanogaster. [FBrf0216591] Lin et al., 2011, PLoS Genet. 7(12): e1002408 Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone. [FBrf0217066] Show all research papers ...