SSRP1, dSSRP1
transcription factor - along with Dre4 forms a protein complex, FACT, that facilates GAGA factor directed chromatin remodeling
Please see the JBrowse view of Dmel\Ssrp for information on other features
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
2.6 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
723 (aa); 81 (kD)
Component of the FACT complex, a stable heterodimer of dre4/spt16 and Ssrp. Interacts with CHD1 and TRL/GAGA.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ssrp using the Feature Mapper tool.
Comment: maternally deposited
Ssrp transcripts are found in ovaries and are abundant throughout oogenesis. Transcripts are also found in nurse cells and the nurse cell expression is highest during stages S10-S12. Transcript levels remain high during embryogenesis but drop during larval stages.
Ssrp protein is localized to the nucleus and is particularly abundant in the nucleolus.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Ssrp in GBrowse 22-105
2-105
2-109.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Ssrp CG4817
Drosophila Ssrp identified by sequence similarity to human Ssrp gene.
cDNA encoding a developmentally regulated high-mobility-group (HMG) box-containing protein was isolated: the encoded protein binds single stranded DNA and RNA, rather than the expected structured DNA.