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Gene Dmel\Ssrp

General Information
Symbol	Dmel\Ssrp	Species	D. melanogaster
Name	Structure specific recognition protein	Annotation symbol	CG4817
Feature type	protein_coding_gene	FlyBase ID	FBgn0010278
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	SSRP1, dSSRP1, dSSRP
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60A2-60A2	Sequence location	2R:19,693,884..19,696,518 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Structure specific recognition protein is referred to in FlyBase by the symbol Dmel\Ssrp (CG4817, FBgn0010278). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: nucleosomal DNA binding; protein binding; protein self-association. There is experimental evidence that it is involved in the biological process: regulation of DNA binding; regulation of chromatin assembly or disassembly; neurogenesis. 8 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Domain of unknown function DUF1747; High mobility group (HMG) box domain; Pleckstrin homology-like domain; SSRP1 domain; Structure-specific recognition protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1624815_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Ssrp. Gene sequence location is 2R:19693884..19696518.
User Contributed Data
	Beta version, feedback welcome
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60A2-60A2   Limits computationally determined from genome sequence between P{EP}eglEP938 and P{lacW}eIF6k13214
Experimentally Determined Cytological Location
Cytogenetic map Notes References 60A1-60A4     (Bruhn, 1992.9.16) 60A1-60A4   (determined by in situ hybridisation)   (Hsu et al., 1993) 60A1-60A4   (determined by in situ hybridisation)   (Bruhn et al., 1993)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ssrp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ssrp-RA FBtr0072242  NM_079106   2498   723
Additional Transcript Data & Comments
Reported size (kB)	2.6 (northern blot) (Hsu et al., 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ssrp-PA   FBpp0072151   81.5   723   5.31     NP_523830   AAF47064
Additional Polypeptide Data & Comments
Reported size (kDa)	723 (aa); 81 (kD) (Hsu et al., 1993, Bruhn et al., 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1747 (IPR013719) SSRP1 domain (IPR024954) Structure-specific recognition protein (IPR000969) High mobility group (HMG) box domain (IPR009071) Pleckstrin homology-like domain (IPR011993)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA390604   AA540678   AA696623   AA802337   AA802829   AE013599 AAF47064   AI534034   AW944457   BF490475   BF500709   BG634972   BG640734   BI169603   BI238760   BI351600   BI355848   BI356671   BP544470   BP545863   BP558726   BT004831 AAO45187   BT044339   CO181709   CO265880   CO284192   CO285670   CO300283   CO301016   CO319705   CO330550   EC198916   EC199671   EC200207   EC204953   EC211489   EC215867   EC222911   GH749702   GH755032   GH756309   GH757624   GH758571   GH760471   GH770116   GH773945   GH779042   GH782653   GH785523   GH788876   GH790154   GH794140   GH794567   GH795026   GH799828   GH800239   GH800973   GH801541   GH801626   GH802560   GH803395   GH812184   GH813145   GH814239   GH814636   GH818475   GH818780   GH820338   GH820946   GH822268   GH825953   GH826452   GH827761   GH830216   GH830861   GH839396   GH839445   GH839592   GH839920   GH841019   GH844025   GH844401   GH847572   GH847872   GH848389   GH849460   GH851921   GH855384   GH857794   GH860905   GH862108   GH864070   GH866332   GH866815   GH867993   GH870347   GH870690   GH872260   GH874719   GH875040   GH875670   GH877013   GH879536   GH880806   GH884247   GH885085   GH886177   GH887887   GH888089   GH888324   GH893552   GH897247   GH897477   GH897567   GH897661   GH898102   GH901785   GH901916   GH904723   GH906932   GH910077   GH911061   GH914546   GH914658   GH918707   GH919837   GH921087   GH921837   GH924633   GH924709   GH924840   GH929912   GH931286   GH931515   GH931783   GH932534   GH932832   GH934821   GH940553   L08825 AAA28914   X68408 CAA48471
UniProtKB/Swiss-Prot	Q05344
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference oogenesis & adult stage | female   ovary   (Hsu et al., 1993) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | intense & ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   central brain primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012) adult stage & oogenesis   nurse cell   (Hsu et al., 1993)
Additional Descriptive Data
	Ssrp transcripts are found in ovaries and are abundant throughout oogenesis. Transcripts are also found in nurse cells and the nurse cell expression is highest during stages S10-S12. Transcript levels remain high during embryogenesis but drop during larval stages. (Hsu et al., 1993)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
	Ssrp protein is localized to the nucleus and is particularly abundant in the nucleolus. (Hsu et al., 1993)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
FACT complex inferred from direct assay (Tsunaka et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    413.25 Larval Midgut    60.1 Larval Hindgut    75.9 Larval Malpighian Tubules    36 Larval Fat Body    61 Larval Salivary Gland    129.1 Larval Trachea    163.8 Larval Carcass    95.775 Adult Head    51 Adult Eye    35.475 Adult Brain    65.6 Adult Thoracic-Abdominal Ganglion    70.3 Adult Crop    46.9 Adult Midgut    48.2 Adult Hindgut    52.2 Adult Malpighian Tubules    51.6 Adult Fat Body    53.2 Adult Salivary Gland    36.6 Adult Heart    30.675 Adult VirginFemale Spermatheca    40 Adult InseminatedFemale Spermatheca    46.5 Adult Ovary    404.7 Adult Testis    107.4 Adult Male Accessory Gland    109.7 Adult Carcass    52.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    51   NA  Eye    35.475   NA  Brain    65.6   413.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    70.3   NA  Crop    46.9   60.1  Midgut    48.2   75.9  Hindgut    52.2   36  Malpighian Tubules    51.6   61  Fat Body    53.2   129.1  Salivary Gland    no informative data   NA  Heart    30.675   163.8  Trachea    NA   NA  VirginFemale Spermatheca    40   NA  InseminatedFemale Spermatheca    46.5   NA  Ovary    404.7   NA  Testis    107.4   NA  Male Accessory Gland    109.7   95.775  Carcass    52.3 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    142 central nervous system, larvae L3    156 central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering    112 carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female    189 ovary, mated 4-day female    275 testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (142) central nervous system, larvae L3  (156) central nervous system, pupae P8  (38) head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult  (32) digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae  (30) fat body, pupae P8  (42) carcass, larvae L3 wandering  (112) carcass, 1-day adult    16 carcass, 4-day adult  (31) carcass, 20-day adult    22 ovary, virgin 4-day female  (189) ovary, mated 4-day female  (275) testis, mated 4-day male  (62) accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (142) central nervous system, larvae L3  (156) central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering  (112) carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female  (189) ovary, mated 4-day female  (275) testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    142 central nervous system, larvae L3    156 central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering    112 carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female    189 ovary, mated 4-day female    275 testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    142 central nervous system, larvae L3    156 central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering    112 carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female    189 ovary, mated 4-day female    275 testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (142) central nervous system, larvae L3  (156) central nervous system, pupae P8  (38) head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult  32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae  30 fat body, pupae P8  (42) carcass, larvae L3 wandering  (112) carcass, 1-day adult    16 carcass, 4-day adult  31 carcass, 20-day adult    22 ovary, virgin 4-day female  (189) ovary, mated 4-day female  (275) testis, mated 4-day male  (62) accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  142 central nervous system, larvae L3  (156) central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering  112 carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female  (189) ovary, mated 4-day female  (275) testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    142 central nervous system, larvae L3    156 central nervous system, pupae P8    38 head, virgin 1-day female    12 head, virgin 4-day female    16 head, virgin 20-day female    10 head, mated 1-day female    16 head, mated 4-day female    17 head, mated 20-day female    10 head, mated 1-day male    16 head, mated 4-day male    20 head, mated 20-day male    24 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    11 digestive system, larvae L3 wandering    23 digestive system, 1-day adult    15 digestive system, 4-day adult    32 digestive system, 20-day adult    21 fat body, larvae L3 wandering    15 fat body, white prepupae    30 fat body, pupae P8    42 carcass, larvae L3 wandering    112 carcass, 1-day adult    16 carcass, 4-day adult    31 carcass, 20-day adult    22 ovary, virgin 4-day female    189 ovary, mated 4-day female    275 testis, mated 4-day male    62 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    128 embryo 02-04hr    48 embryo 04-06hr    114 embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (128) embryo 02-04hr  (48) embryo 04-06hr  (114) embryo 06-08hr  (82) embryo 08-10hr  (55) embryo 10-12hr  (29) embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1  (31) larva L2  (30) larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6  (33) larva L3 puffstage 7-9  (35) white prepupae new  (31) white prepupae 12hr  (46) white prepupae 24hr  (47) pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day  (53) adult female 05day  (89) adult female 30day  (88) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (128) embryo 02-04hr    48 embryo 04-06hr  (114) embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    128 embryo 02-04hr    48 embryo 04-06hr    114 embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    128 embryo 02-04hr    48 embryo 04-06hr    114 embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (128) embryo 02-04hr  (48) embryo 04-06hr  (114) embryo 06-08hr  (82) embryo 08-10hr  (55) embryo 10-12hr  29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1  31 larva L2  30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6  (33) larva L3 puffstage 7-9  (35) white prepupae new  31 white prepupae 12hr  (46) white prepupae 24hr  (47) pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day  (53) adult female 05day  (89) adult female 30day  (88) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  128 embryo 02-04hr    48 embryo 04-06hr  114 embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    128 embryo 02-04hr    48 embryo 04-06hr    114 embryo 06-08hr    82 embryo 08-10hr    55 embryo 10-12hr    29 embryo 12-14hr    18 embryo 14-16hr    15 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    6 embryo 22-24hr    7 larva L1    31 larva L2    30 larva L3 12hr old    21 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    35 white prepupae new    31 white prepupae 12hr    46 white prepupae 24hr    47 pupae 2d postWPP    22 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    12 adult male 05day    16 adult male 30day    16 adult female 01day    53 adult female 05day    89 adult female 30day    88 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    252 Schneider line 2 Sg4    216 embryonic 1182-4H    280 embryonic GM2    191 embryonic Kc167    188 embryonic S1    477 embryonic S3    210 leg disc CME L1    281 wing disc CME-W2    189 wing disc ML-DmD8    164 wing disc ML-DmD9    317 wing disc ML-DmD16-c3    445 wing disc ML-DmD21    413 wing disc ML-DmD32    252 haltere disc ML-DmD17-c3    381 eye-antennal disc ML-DmD11    336 antennal disc ML-DmD20-c5    269 mixed discs ML-DmD4-c1    237 CNS ML-DmBG1-c1    470 CNS ML-DmBG2-c2    147 tumorous blood cells mbn2    111 ovary fGS/OSS    595 ovary OSC    439 ovary OSS    241 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (252) Schneider line 2 Sg4  (216) embryonic 1182-4H  (280) embryonic GM2  (191) embryonic Kc167  (188) embryonic S1  (477) embryonic S3  (210) leg disc CME L1  (281) wing disc CME-W2  (189) wing disc ML-DmD8  (164) wing disc ML-DmD9  (317) wing disc ML-DmD16-c3  (445) wing disc ML-DmD21  (413) wing disc ML-DmD32  (252) haltere disc ML-DmD17-c3  (381) eye-antennal disc ML-DmD11  (336) antennal disc ML-DmD20-c5  (269) mixed discs ML-DmD4-c1  (237) CNS ML-DmBG1-c1  (470) CNS ML-DmBG2-c2  (147) tumorous blood cells mbn2  (111) ovary fGS/OSS  (595) ovary OSC  (439) ovary OSS  (241) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (252) Schneider line 2 Sg4  (216) embryonic 1182-4H  (280) embryonic GM2  (191) embryonic Kc167  (188) embryonic S1  (477) embryonic S3  (210) leg disc CME L1  (281) wing disc CME-W2  (189) wing disc ML-DmD8  (164) wing disc ML-DmD9  (317) wing disc ML-DmD16-c3  (445) wing disc ML-DmD21  (413) wing disc ML-DmD32  (252) haltere disc ML-DmD17-c3  (381) eye-antennal disc ML-DmD11  (336) antennal disc ML-DmD20-c5  (269) mixed discs ML-DmD4-c1  (237) CNS ML-DmBG1-c1  (470) CNS ML-DmBG2-c2  (147) tumorous blood cells mbn2  (111) ovary fGS/OSS  (595) ovary OSC  (439) ovary OSS  (241) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    252 Schneider line 2 Sg4    216 embryonic 1182-4H    280 embryonic GM2    191 embryonic Kc167    188 embryonic S1    477 embryonic S3    210 leg disc CME L1    281 wing disc CME-W2    189 wing disc ML-DmD8    164 wing disc ML-DmD9    317 wing disc ML-DmD16-c3    445 wing disc ML-DmD21    413 wing disc ML-DmD32    252 haltere disc ML-DmD17-c3    381 eye-antennal disc ML-DmD11    336 antennal disc ML-DmD20-c5    269 mixed discs ML-DmD4-c1    237 CNS ML-DmBG1-c1    470 CNS ML-DmBG2-c2    147 tumorous blood cells mbn2    111 ovary fGS/OSS    595 ovary OSC    439 ovary OSS    241 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    252 Schneider line 2 Sg4    216 embryonic 1182-4H    280 embryonic GM2    191 embryonic Kc167    188 embryonic S1    477 embryonic S3    210 leg disc CME L1    281 wing disc CME-W2    189 wing disc ML-DmD8    164 wing disc ML-DmD9    317 wing disc ML-DmD16-c3    445 wing disc ML-DmD21    413 wing disc ML-DmD32    252 haltere disc ML-DmD17-c3    381 eye-antennal disc ML-DmD11    336 antennal disc ML-DmD20-c5    269 mixed discs ML-DmD4-c1    237 CNS ML-DmBG1-c1    470 CNS ML-DmBG2-c2    147 tumorous blood cells mbn2    111 ovary fGS/OSS    595 ovary OSC    439 ovary OSS    241 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (252) Schneider line 2 Sg4  (216) embryonic 1182-4H  (280) embryonic GM2  (191) embryonic Kc167  (188) embryonic S1  (477) embryonic S3  (210) leg disc CME L1  (281) wing disc CME-W2  (189) wing disc ML-DmD8  (164) wing disc ML-DmD9  (317) wing disc ML-DmD16-c3  (445) wing disc ML-DmD21  (413) wing disc ML-DmD32  (252) haltere disc ML-DmD17-c3  (381) eye-antennal disc ML-DmD11  (336) antennal disc ML-DmD20-c5  (269) mixed discs ML-DmD4-c1  (237) CNS ML-DmBG1-c1  (470) CNS ML-DmBG2-c2  (147) tumorous blood cells mbn2  (111) ovary fGS/OSS  (595) ovary OSC  (439) ovary OSS  (241) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (252) Schneider line 2 Sg4  (216) embryonic 1182-4H  (280) embryonic GM2  (191) embryonic Kc167  (188) embryonic S1  (477) embryonic S3  (210) leg disc CME L1  (281) wing disc CME-W2  (189) wing disc ML-DmD8  (164) wing disc ML-DmD9  (317) wing disc ML-DmD16-c3  (445) wing disc ML-DmD21  (413) wing disc ML-DmD32  (252) haltere disc ML-DmD17-c3  (381) eye-antennal disc ML-DmD11  (336) antennal disc ML-DmD20-c5  (269) mixed discs ML-DmD4-c1  (237) CNS ML-DmBG1-c1  (470) CNS ML-DmBG2-c2  (147) tumorous blood cells mbn2  111 ovary fGS/OSS  (595) ovary OSC  (439) ovary OSS  (241) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    252 Schneider line 2 Sg4    216 embryonic 1182-4H    280 embryonic GM2    191 embryonic Kc167    188 embryonic S1    477 embryonic S3    210 leg disc CME L1    281 wing disc CME-W2    189 wing disc ML-DmD8    164 wing disc ML-DmD9    317 wing disc ML-DmD16-c3    445 wing disc ML-DmD21    413 wing disc ML-DmD32    252 haltere disc ML-DmD17-c3    381 eye-antennal disc ML-DmD11    336 antennal disc ML-DmD20-c5    269 mixed discs ML-DmD4-c1    237 CNS ML-DmBG1-c1    470 CNS ML-DmBG2-c2    147 tumorous blood cells mbn2    111 ovary fGS/OSS    595 ovary OSC    439 ovary OSS    241 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult    198 Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult    110 Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3    160 Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    170 Caffeine 25 mg/ml 48 hrs, 4-day adult    102 Paraquat 5 mM 48 hrs, 4-day adult    137 Paraquat 10 mM 48 hrs, 4-day adult    127 Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult  (77) heat shock, 4-day adult  (91) Cadmium 50 mM 6 hrs, larvae L3  (36) Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult  (97) Cadmium 100 mM 48 hrs, 4-day adult  (198) Copper 0.5 mM 12 hrs, larvae L3  (92) Copper 15 mM 48 hrs, 4-day adult  (110) Zinc 5 mM 12 hrs, larvae L3  (65) Zinc 4.5 mM 48 hrs, 4-day adult  (77) Ethanol 2.5% 3 hrs, larvae L3  (160) Ethanol 5% 3 hrs, larvae L3  (28) Ethanol 10% 3 hrs, larvae L3  (38) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (27) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (170) Caffeine 25 mg/ml 48 hrs, 4-day adult  (102) Paraquat 5 mM 48 hrs, 4-day adult  (137) Paraquat 10 mM 48 hrs, 4-day adult  (127) Rotenone 2 μg 12 hrs, larvae L3  (39) Rotenone 8 μg 12 hrs, larvae L3  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult  (198) Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult  (110) Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3  (160) Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (170) Caffeine 25 mg/ml 48 hrs, 4-day adult  102 Paraquat 5 mM 48 hrs, 4-day adult  (137) Paraquat 10 mM 48 hrs, 4-day adult  (127) Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult    198 Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult    110 Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3    160 Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    170 Caffeine 25 mg/ml 48 hrs, 4-day adult    102 Paraquat 5 mM 48 hrs, 4-day adult    137 Paraquat 10 mM 48 hrs, 4-day adult    127 Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult    198 Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult    110 Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3    160 Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    170 Caffeine 25 mg/ml 48 hrs, 4-day adult    102 Paraquat 5 mM 48 hrs, 4-day adult    137 Paraquat 10 mM 48 hrs, 4-day adult    127 Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (117) cold shock, 4-day adult  (77) heat shock, 4-day adult  (91) Cadmium 50 mM 6 hrs, larvae L3  (36) Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult  (97) Cadmium 100 mM 48 hrs, 4-day adult  (198) Copper 0.5 mM 12 hrs, larvae L3  (92) Copper 15 mM 48 hrs, 4-day adult  (110) Zinc 5 mM 12 hrs, larvae L3  (65) Zinc 4.5 mM 48 hrs, 4-day adult  (77) Ethanol 2.5% 3 hrs, larvae L3  (160) Ethanol 5% 3 hrs, larvae L3  28 Ethanol 10% 3 hrs, larvae L3  (38) Caffeine 1.5 mg/ml 4 hrs, larvae L3  27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (170) Caffeine 25 mg/ml 48 hrs, 4-day adult  (102) Paraquat 5 mM 48 hrs, 4-day adult  (137) Paraquat 10 mM 48 hrs, 4-day adult  (127) Rotenone 2 μg 12 hrs, larvae L3  (39) Rotenone 8 μg 12 hrs, larvae L3  (43) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  117 cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult  (198) Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult  110 Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3  (160) Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (170) Caffeine 25 mg/ml 48 hrs, 4-day adult  102 Paraquat 5 mM 48 hrs, 4-day adult  137 Paraquat 10 mM 48 hrs, 4-day adult  127 Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    117 cold shock, 4-day adult    77 heat shock, 4-day adult    91 Cadmium 50 mM 6 hrs, larvae L3    36 Cadmium 50 mM 12 hrs, larvae L3    24 Cadmium 50 mM 48 hrs, 4-day adult    97 Cadmium 100 mM 48 hrs, 4-day adult    198 Copper 0.5 mM 12 hrs, larvae L3    92 Copper 15 mM 48 hrs, 4-day adult    110 Zinc 5 mM 12 hrs, larvae L3    65 Zinc 4.5 mM 48 hrs, 4-day adult    77 Ethanol 2.5% 3 hrs, larvae L3    160 Ethanol 5% 3 hrs, larvae L3    28 Ethanol 10% 3 hrs, larvae L3    38 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    170 Caffeine 25 mg/ml 48 hrs, 4-day adult    102 Paraquat 5 mM 48 hrs, 4-day adult    137 Paraquat 10 mM 48 hrs, 4-day adult    127 Rotenone 2 μg 12 hrs, larvae L3    39 Rotenone 8 μg 12 hrs, larvae L3    43 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • SD06504 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010278 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4817-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal SsrpGD12795 lethal | pupal stage, with Scer\GAL4pnr-MD237 SsrpGD12795 Other Phenotypes Allele neuroanatomy defective | larval stage SsrpGD12795 visible, with Scer\GAL4pnr-MD237 SsrpGD12795 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage SsrpGD12795 ganglion mother cell | larval stage SsrpGD12795 mesothoracic tergum, with Scer\GAL4pnr-MD237 SsrpGD12795
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Ssrp Class Mutagen Stocks Known lesion SsrpG2947 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ssrp Class Mutagen Stocks Known lesion SsrpGD12795 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes SsrpGL00381 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SsrpHMS02285 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SsrpJF02120 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes SsrpdsRNA.cHa in vitro construct - RNAi 0 Yes SsrpNIG.4817R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes SsrpScer\UAS.cBa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12795} NA P{NIG.4817R} NA P{TRiP.GL00381} NA P{TRiP.HMS02285} NA P{TRiP.JF02120} NA P{UAS-Ssrp.B} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}SsrpG2947 NA
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 7 terms )
Molecular Function
CV term Evidence References
nucleosomal DNA binding inferred from direct assay (Tsunaka et al., 2009) protein binding inferred from physical interaction with Trl (Shimojima et al., 2003) protein self-association inferred from direct assay (Tsunaka et al., 2009)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011) regulation of chromatin assembly or disassembly inferred from mutant phenotype (Shimojima et al., 2003) regulation of DNA binding inferred from mutant phenotype (Tsunaka et al., 2009)
Cellular Component
CV term Evidence References
FACT complex inferred from direct assay (Tsunaka et al., 2009)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
DNA secondary structure binding inferred from sequence or structural similarity with UniProtKB:Q08945 (FlyBase, 1992-) single-stranded DNA binding inferred from sequence or structural similarity with UniProtKB:Q08945 (FlyBase, 1992-) non-traceable author statement (Hsu, 1993, Swiss-Prot Project Members, 1994.10.1) single-stranded RNA binding non-traceable author statement (Hsu, 1993, Swiss-Prot Project Members, 1994.10.1)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
FACT complex traceable author statement (Lehmann, 2004) nucleolus non-traceable author statement (Hsu, 1993, Swiss-Prot Project Members, 1994.10.1) nucleus inferred from sequence or structural similarity with UniProtKB:Q08945 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1994.10.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Ssrp - CG3165 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - CkIIβ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - Dek experimental knowledge based (Guruharsha et al., 2011) Ssrp - GABPI anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - Pof anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Ssrp - dre4 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ssrp allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63363 DroID - A comprehensive database of gene and protein interactions. • FBgn0010278 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37767
Orthologs
OrthoDB Orthologs (44) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6ZCTQ2 Dipteran inclusive ortholog search EOG63JCCX Insect inclusive ortholog search EOG608M48 Arthropod inclusive ortholog search EOG6PG4G5 Metazoa inclusive ortholog search EOG6DVJDP
Orthologs in Drosophila Species (EOG6ZCTQ2)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ssrp     Drosophila simulans   Dsim\GD25013 Y   Drosophila sechellia   Dsec\GM15512 Y   Drosophila erecta   Dere\GG19998 Y   Drosophila yakuba   Dyak\GE11532 Y   Drosophila ananassae   Dana\GF12460 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18454 Y   Drosophila persimilis   Dper\GL11071 Y   Drosophila willistoni   Dwil\GK22092 Y   Drosophila virilis   Dvir\GJ21774 Y   Drosophila mojavensis   Dmoj\GI18750 Y   Drosophila grimshawi   Dgri\GH21151 Y
Orthologs in non-Drosophila Dipterans (EOG63JCCX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011425   Anopheles gambiae Malaria mosquito  Agam\AGAP012335   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ002953
Orthologs in non-Dipteran Insects (EOG608M48)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54571   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012617   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15288   Atta cephalotes Leafcutter ant  Acep\ACEP16595   Camponotus floridanus Florida carpenter ant  Cflo\CFLO21126   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14147   Linepithema humile Argentine ant  Lhum\LH12737   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12649   Solenopsis invicta Red fire ant  Sinv\SINV21577   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007174   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006576   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008511   Bombyx mori Silkmoth  Bmor\BGIBMGA005288   Pediculus humanus Human body louse  Phum\PHUM125270   Tribolium castaneum Red flour beetle  Tcas\TC012866
Orthologs in non-Insect Arthropods (EOG6PG4G5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_201206   Ixodes scapularis Deer tick  Isca\ISCW020032
Orthologs in non-Arthropod Metazoa (EOG6DVJDP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\hmg-4   Caenorhabditis elegans Nematode  Cele\hmg-3   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001119gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023988gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025332gn   Danio rerio Zebrafish  Drer\ssrp1b   Danio rerio Zebrafish  Drer\ssrp1a   Xenopus tropicalis Western clawed frog  Xtro\ssrp1   Gallus gallus Domestic chicken  Ggal\SSRP1   Mus musculus House mouse  Mmus\Ssrp1   Rattus norvegicus Norway rat  Rnor\Ssrp1   Homo sapiens Human  Hsap\SSRP1
Human Orthologs (1)
Gene OMIM HGNC Hsap\SSRP1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25013 Drosophila sechellia Dsec\GM15512 Drosophila erecta Dere\GG19998 Drosophila yakuba Dyak\GE11532 Drosophila ananassae Dana\GF12460 Drosophila pseudoobscura pseudoobscura Dpse\GA18454 Drosophila persimilis Dper\GL11071 Drosophila willistoni Dwil\GK22092 Drosophila virilis Dvir\GJ21774 Drosophila mojavensis Dmoj\GI18750 Drosophila grimshawi Dgri\GH21151
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	26222 y1 v1; P{TRiP.JF02120}attP2 29686 y1 w*; P{EP}SsrpG2947/CyO 41719 y1 sc* v1; P{TRiP.HMS02285}attP2 35455 y1 sc* v1; P{TRiP.GL00381}attP2/TM3, Sb1
VDRC	v44343 w1118; P{GD12795}v44343 v44344 w1118; P{GD12795}v44344
Genomic Clones ( 2 )
	BACR02E09 BACR05F24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 135 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD06504
Other clones	FI07619
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT15709 AT26951 AT31395 GM04223 GM06375 GM08028 GM08107 GM32580 LD09673 LD20446 RE10829 RE41825 RE42862 SD11876
Other clones	33431 46497 54477 57057 57423 175537 192427 EC14863 EK144330 EK165450 EK169834 EK177829 EK179912 EK280107 EK295534 FGC026A10 FGH001D01 FGM316G02 RP003015504 RP003059880 RP003066265 RP003094079 RP003115006 RP003121474 RP003121485 RP003127634 RP003132244 RP003141719 RP003149767 RP003153659 RP003161865 RP003166129 RP003170991 RP003182845 RP003194731 RP003202795 RP003204847 RP003209964 RP003218232 RP003219068 RP003226034 RP003229714 RP003232719 RP003233395 RP003238351 RP003248558 RP003249718 RP003263491 RP003263644 RP003264969 RP003281555 RP003284762 RP003289340 RP003291341 RP003296535 RP003309407 RP003309626 RP003310060 RP003311290 RP003320116 RP003330772 RP003331831 RP003333912 RP003337586 RP003342268 RP003352641 RP003354245 RP003355957 RP003356701 RP003358893 RP003359653 RP003370300 RP003402971 RP003408047 RP003429363 RP003453414 RP003456390 RP003461667 RP003477534 RP003484073 RP003484302 RP003484566 RP003489845 RP003490014 RP003495696 RP003508291 RP003508608 RP003508773 RP003513669 RP003522483 RP003528673 RP003538074 RP003538813 RP003539663 RP003540815 RP003541892 RP003544111 RP003553427 RP003583504 RP003595477 RP003595759 RP003617625 RP003626538 RP003629881 RP003635217 RP003644285 RP003648701 RP003649206 RP003649249 RP003654334 RP003663239 RP003663551 RP003664145 RP003670142 RP003670373 RP003673598 RP003676190 RP003676680 RP003682381
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010278 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37767
Antibody Information
	polyclonal (Hsu et al., 1993)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Ssrp CG4817 (Zhang, 1999.11)
Source for database merge of
Additional comments
Other Comments
	The FACT complex (FAcilitates Chromatin Transcription) containing dre4 and Ssrp has a crucial role in the modulation of chromatin structure for the regulation of gene expression. (Shimojima et al., 2003) Drosophila Ssrp identified by sequence similarity to human Ssrp gene. (Bruhn et al., 1993) cDNA encoding a developmentally regulated high-mobility-group (HMG) box-containing protein was isolated: the encoded protein binds single stranded DNA and RNA, rather than the expected structured DNA. (Hsu et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079106 RefSeq (Proteins) • NP_523830 DDBJ / EMBL / GenBank • AAA28914 AAF47064 AAO45187 AI534034 AW944457 BT004831 CAA48471 L08825 X68408 Entrez Gene - A searchable database of RefSeq genes. • 37767 UniProtKB/Swiss-Prot • Q05344
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1747 (IPR013719) SSRP1 domain (IPR024954) Structure-specific recognition protein (IPR000969) High mobility group (HMG) box domain (IPR009071) Pleckstrin homology-like domain (IPR011993) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • SD06504
Linkouts
	BioGRID - A database of protein and genetic interactions • 63363 DroID - A comprehensive database of gene and protein interactions. • FBgn0010278 DRSC - Results from RNAi screens. • FBgn0010278 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010278 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4817-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010278 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37767 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/fact.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37767 modMine - Data generated by the modENCODE project. • FBgn0010278
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	Cf5   CG4817 (Perkins et al., 2009.3.31, Ni et al., 2011.7.19, Ni et al., 2010.12.1) dSSRP (Wisniewski et al., 1999) DssRP (Hsu et al., 1993) dSsrp (Yokoyama et al., 2007) dSSRP1 (Lehmann, 2004, Shimojima et al., 2003, Nakayama et al., 2007, Tsunaka et al., 2009, Kwon et al., 2010) ssrp (Levine and Begun, 2008) SSRP (Hsu, 1993, Andersen et al., 2010) Ssrp (Sessa and Bianchi, 2007, Grimberg et al., 2011, Farny et al., 2008, Mourikis et al., 2010, Garcia and Stathopoulos, 2011, Wang et al., 2013, Berger et al., 2012, Japanese National Institute of Genetics, 2012.5.21) SSRP1 (Polo, 2006, Saunders et al., 2003, Bruhn, 1992.9.16, Soullier et al., 1999, Kelley et al., 1999, Nakayama et al., 2012)
Name Synonym	Chorion factor   structure-specific recognition protein (Pedersen et al., 2008) Structure specific recognition protein
Secondary FlyBase IDs
	FBgn0005644
References ( 48 )
Generate a list of	All references relating to this gene ( 48 )
List References by type	Research paper  ( 23 ) Supplementary material  ( 6 ) Review  ( 2 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) Protein sequence record  ( 1 ) Website  ( 1 )
Recent research papers ( 5 )
	Wang et al., 2013, Nat. Struct. Mol. Biol. 20(2): 202--209 Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. [FBrf0220693] Berger et al., 2012, Cell Rep. 2(2): 407--418 FACS Purification and Transcriptome Analysis of Drosophila Neural Stem Cells Reveals a Role for Klumpfuss in Self-Renewal. [FBrf0219320] Nakayama et al., 2012, Development 139(24): 4582--4590 The PBAP remodeling complex is required for histone H3.3 replacement at chromatin boundaries and for boundary functions. [FBrf0219981] Garcia and Stathopoulos, 2011, PLoS ONE 6(12): e29172 Lateral gene expression in Drosophila early embryos is supported by grainyhead-mediated activation and tiers of dorsally-localized repression. [FBrf0217082] Grimberg et al., 2011, Mol. Cell. Biol. 31(4): 897--909 Basic Leucine Zipper Protein Cnc-C Is a Substrate and Transcriptional Regulator of the Drosophila 26S Proteasome. [FBrf0212906] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...