lio, linotte
Please see the JBrowse view of Dmel\pigeon for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.44
Gene model reviewed during 5.45
3.5 (northern blot)
None of the polypeptides share 100% sequence identity.
915 (aa); 103 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pigeon using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
lio transcripts are expressed at high levels in early embryos and in adult heads and bodies. They are detected at lower levels in late embryos and pupae, but not in larvae.
JBrowse - Visual display of RNA-Seq signals
View Dmel\pigeon in JBrowse2-54
2-53.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In the absence of rescue data (see pigeonhs.PB) there is insufficient evidence to conclude that the pigeon transcript is involved in adult olfactory learning.
Stated to play a role in associative learning (GO:0008306) and olfactory learning (GO:0008355) however subsequent publication (Bolwig et al., 2002, Neuron 34: 667) retracts that claim.
'lio' is involved with learning and memory.
Behaviour-genetic data suggests that 'lio' is non-vital.
The gene described as 'lio' in FBrf0083123 is drl (FBgn0015380), as is made clear by comparison of molecular maps in FBrf0083123 and FBrf0083785.
FlyBase curator comment: pigeon and drl are neighboring genes, pigeon being 5' and distal to drl. Confusingly, both pigeon and drl have been referred to as 'lio' in the literature. e.g. the gene described as 'lio' in FBrf0083123 is drl (FBgn0015380), the gene described as 'lio' in FBrf0083785 is pigeon (FBgn0010309).
Named from the French expression "tete de linotte" having the same idiomatic meaning as "bird-brain".
In French someone who forgets everything is said to be a "tete de linotte," the equivalent of bird-brain in English.
