Cks, rem, Cdi2, remnants
Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Forms a homohexamer that can probably bind six kinase subunits.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cks30A using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Cks30A in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Cks30A has a role in the metaphase to anaphase transition in female meiosis and in the mitotic divisions of the syncytial embryo.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Yeast two-hybrid system has been used to characterise Cyclin-dependent kinase interactor proteins (the prey) in hunts with either cdc2 or cdc2c as baits. Cks30A interacts with cdc2 cdc2c and CycJ, and other human and S.cerevisiae cyclin-dependent kinases to activate transcription of a reporter gene, Ecol\lacZ.