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Gene Dmel\Map60

General Information
Symbol	Dmel\Map60	Species	D. melanogaster
Name	Microtubule-associated protein 60	Annotation symbol	CG1825
Feature type	protein_coding_gene	FlyBase ID	FBgn0010342
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	CP60, DMAP60
Genomic Location
Chromosome (arm)	2R	Recombination map	2-
Cytogenetic map	45F5-45F6	Sequence location	2R:5,478,331..5,480,249 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Microtubule-associated protein 60 is referred to in FlyBase by the symbol Dmel\Map60 (CG1825, FBgn0010342). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: microtubule binding. Based on sequence similarity, it is predicted to be involved in the biological process: microtubule-based process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval salivary gland, larval trachea, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1629576_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Map60. Gene sequence location is 2R:5478331..5480249.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA07464 BKN31148 References Kanesaki et al., 2011, Integr. Biol. (Camb.) 3(11): 1112--1119
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 45F5-45F6   Limits computationally determined from genome sequence between P{lacW}l(2)k09501k09501 and P{PZ}Mmp202353&P{PZ}Uba105642
Experimentally Determined Cytological Location
Cytogenetic map Notes References 46A-46A     (Kellogg, 1995.10.10) 46A-46A     (Kellogg et al., 1995) 46A-46A   (determined by in situ hybridisation)   (Raff et al., 1992)
Experimentally Determined Recombination Data
Location	2- (Kellogg, 1995.10.10)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Map60 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Map60-RA FBtr0088530  NM_057604   1855   440
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Map60-PA   FBpp0087613   47.6   440   6.75     NP_476952   AAF58917
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202568   AA202779   AA203002   AA263530   AA264412   AA391931   AA392140   AA392203   AA392980   AA392989   AA439322   AA440670   AA539499   AA540435   AA540587   AA540619   AA540717   AA540957   AA735252   AA816414   AA816585   AA816756   AA820219   AA820693   AA941782   AA941958   AA942245   AA950324   AA951961   AE013599 AAF58917   AC006472   AI293686   AI295155   AI402465   AI455670   AI456206   AI456635   AI457059   AI512157   AI512819   AI513448   AI514875   AI515881   AI516448   AI516449   AI516483   AI518018   AI518108   AI546265   AW942030   AY069313 AAL39458   BI164751   BI164842   BI166615   BI169830   BI170239   BI212431   BI214713   BI214969   BI216220   BI216399   BI229629   BI234852   BI235789   BI236825   BI237605   BI237967   BI239276   BI243879   BI357197   BI357239   BI361328   BI367811   BI368723   BI370141   BI371707   BI371716   BI371826   BI372147   BI374918   BI482277   BI485249   BI577375   BI580156   BI632685   BI636764   BI637298   BI637913   BI639166   BI641007   BP541198   BP541199   BP557967   BP557968   BZ286221   CK657896   CK660588   CK661890   CO179002   CO190352   CO276010   CO276198   CO316647   CO317407   CO318762   CO331530   CO332244   CO340337   CO340706   EC089531   EC089812   EC197535   EC202140   EC218656   EC220346   EC224432   EC226924   EC227998   EC228189   EC234021   EC235756   EC250236   EC250966   EC252100   EC254613   U38248 AAB00184
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q24147 Q7K180
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0010342    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0010342 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0010342 expression level Developmental Stage   Expression Level embryo 00-02hr    11914 embryo 02-04hr    19242 embryo 04-06hr    16765 embryo 06-08hr    14232 embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (11914) embryo 02-04hr  (19242) embryo 04-06hr  (16765) embryo 06-08hr  (14232) embryo 08-10hr  (9880) embryo 10-12hr  (6683) embryo 12-14hr  (4316) embryo 14-16hr  (4446) embryo 16-18hr  (3625) embryo 18-20hr  (2021) embryo 20-22hr  (6726) embryo 22-24hr  (4548) larva L1  (718) larva L2  (556) larva L3 12hr old  (635) larva L3 puffstage 1-2  (1163) larva L3 puffstage 3-6  (1919) larva L3 puffstage 7-9  (2278) white prepupae new  (2247) white prepupae 12hr  (3736) white prepupae 24hr  (3908) pupae 2d postWPP  (1556) pupae 3d postWPP  (516) pupae 4d postWPP  (407) adult male 01day  (285) adult male 05day  (346) adult male 30day  (306) adult female 01day  (2107) adult female 05day  (4847) adult female 30day  (5332) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (11914) embryo 02-04hr  (19242) embryo 04-06hr  (16765) embryo 06-08hr  (14232) embryo 08-10hr  (9880) embryo 10-12hr  (6683) embryo 12-14hr  (4316) embryo 14-16hr  (4446) embryo 16-18hr  (3625) embryo 18-20hr  (2021) embryo 20-22hr  (6726) embryo 22-24hr  (4548) larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6  (1919) larva L3 puffstage 7-9  (2278) white prepupae new  (2247) white prepupae 12hr  (3736) white prepupae 24hr  (3908) pupae 2d postWPP  (1556) pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day  (2107) adult female 05day  (4847) adult female 30day  (5332) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (11914) embryo 02-04hr  (19242) embryo 04-06hr  (16765) embryo 06-08hr  (14232) embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11914 embryo 02-04hr    19242 embryo 04-06hr    16765 embryo 06-08hr    14232 embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0010342 expression level Developmental Stage   Expression Level embryo 00-02hr    11914 embryo 02-04hr    19242 embryo 04-06hr    16765 embryo 06-08hr    14232 embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (11914) embryo 02-04hr  (19242) embryo 04-06hr  (16765) embryo 06-08hr  (14232) embryo 08-10hr  (9880) embryo 10-12hr  (6683) embryo 12-14hr  (4316) embryo 14-16hr  (4446) embryo 16-18hr  (3625) embryo 18-20hr  (2021) embryo 20-22hr  (6726) embryo 22-24hr  (4548) larva L1  (718) larva L2  (556) larva L3 12hr old  (635) larva L3 puffstage 1-2  (1163) larva L3 puffstage 3-6  (1919) larva L3 puffstage 7-9  (2278) white prepupae new  (2247) white prepupae 12hr  (3736) white prepupae 24hr  (3908) pupae 2d postWPP  (1556) pupae 3d postWPP  (516) pupae 4d postWPP  (407) adult male 01day  (285) adult male 05day  (346) adult male 30day  (306) adult female 01day  (2107) adult female 05day  (4847) adult female 30day  (5332) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (11914) embryo 02-04hr  (19242) embryo 04-06hr  (16765) embryo 06-08hr  (14232) embryo 08-10hr  (9880) embryo 10-12hr  (6683) embryo 12-14hr  (4316) embryo 14-16hr  (4446) embryo 16-18hr  (3625) embryo 18-20hr  2021 embryo 20-22hr  (6726) embryo 22-24hr  (4548) larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6  1919 larva L3 puffstage 7-9  2278 white prepupae new  2247 white prepupae 12hr  (3736) white prepupae 24hr  (3908) pupae 2d postWPP  1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day  2107 adult female 05day  (4847) adult female 30day  (5332) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  11914 embryo 02-04hr  19242 embryo 04-06hr  16765 embryo 06-08hr  14232 embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11914 embryo 02-04hr    19242 embryo 04-06hr    16765 embryo 06-08hr    14232 embryo 08-10hr    9880 embryo 10-12hr    6683 embryo 12-14hr    4316 embryo 14-16hr    4446 embryo 16-18hr    3625 embryo 18-20hr    2021 embryo 20-22hr    6726 embryo 22-24hr    4548 larva L1    718 larva L2    556 larva L3 12hr old    635 larva L3 puffstage 1-2    1163 larva L3 puffstage 3-6    1919 larva L3 puffstage 7-9    2278 white prepupae new    2247 white prepupae 12hr    3736 white prepupae 24hr    3908 pupae 2d postWPP    1556 pupae 3d postWPP    516 pupae 4d postWPP    407 adult male 01day    285 adult male 05day    346 adult male 30day    306 adult female 01day    2107 adult female 05day    4847 adult female 30day    5332 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0010342    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0010342 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval salivary gland, larval trachea, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0010342 expression level Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (682.3) Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary  (675.3) Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0010342 expression level Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary  675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    682.3 Larval Midgut    45.1 Larval Hindgut    74.9 Larval Malpighian Tubules    90.1 Larval Fat Body    87 Larval Salivary Gland    139.1 Larval Trachea    219.25 Larval Carcass    139.1 Adult Head    58.3 Adult Eye    61.525 Adult Brain    156.4 Adult Thoracic-Abdominal Ganglion    107.6 Adult Crop    51.2 Adult Midgut    41.7 Adult Hindgut    37.5 Adult Malpighian Tubules    35 Adult Fat Body    31 Adult Salivary Gland    53.5 Adult Heart    31.625 Adult VirginFemale Spermatheca    27.5 Adult InseminatedFemale Spermatheca    31.1 Adult Ovary    675.3 Adult Testis    35 Adult Male Accessory Gland    37.5 Adult Carcass    34.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    58.3   NA  Eye    61.525   NA  Brain    156.4   682.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    107.6   NA  Crop    51.2   45.1  Midgut    41.7   74.9  Hindgut    37.5   90.1  Malpighian Tubules    35   87  Fat Body    31   139.1  Salivary Gland    53.5   NA  Heart    31.625   219.25  Trachea    NA   NA  VirginFemale Spermatheca    27.5   NA  InseminatedFemale Spermatheca    31.1   NA  Ovary    675.3   NA  Testis    35   NA  Male Accessory Gland    37.5   139.1  Carcass    34.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010342 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1825-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Map60 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Map60CB03167 Map60Ubi-p63E.PB viable, with Scer\GAL4pnr-MD237 Map60GD9538 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Map60 Class Mutagen Stocks Known lesion Map60KG00506 P-element activity 1 -- Map60CB03167 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Map60 Class Mutagen Stocks Known lesion Map60GD9538 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Map60HMS00457 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Map60fl.T:Zzzz\His6 in vitro construct - coding region fusion 0 Yes Map60Ubi-p63E.PB in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel8049 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9538} NA P{TRiP.HMS00457} NA characterization construct P{Ubi-Map60.D} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{PTT-GB}Map60CB03167 NA P{SUPor-P}Map60KG00506 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
centrosome inferred from direct assay (Butcher et al., 2004, Kellogg et al., 1995) inferred from physical interaction with Cp190 (Kellogg et al., 1995) nucleus inferred from direct assay (Butcher et al., 2004)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
microtubule binding inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Biological Process
CV term Evidence References
microtubule-based process inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Cellular Component
CV term Evidence References
centrosome non-traceable author statement (Kellogg, 1995.10.10) microtubule associated complex inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000) non-traceable author statement (Kellogg, 1995.10.10)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Map60 allele Gene References unspecified Cp190 (Butcher et al., 2004)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61822 DroID - A comprehensive database of gene and protein interactions. • FBgn0010342 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35991
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12481 Dere\GG24091 Dgri\GH22933 Dmoj\GI18419 Dper\GL17148 Dpse\GA14854 Dsec\GM21138 Dsim\GD10668 Dvir\GJ21505 Dwil\GK15949 Dyak\GE19291
Curated drosophilid orthologs	Dhet\Map60 (Davis, 1998.2.10) Dpse\GA14854
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0236641 FBgn0217951 FBgn0182435 FBgn0176019 FBgn0074881 FBgn0154752 FBgn0130390 FBgn0116230 FBgn0089518
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	32458 y1 sc* v1; P{TRiP.HMS00457}attP2 14880 y1; P{SUPor-P}Map60KG00506/SM6a; ry506
VDRC	v25306 w1118; P{GD9538}v25306
Genomic Clones ( 1 )
	BACR48G21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 117 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD02709
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH21691 LD01468 LD01681 LD02130 LD03101 LD03567 LD06688 LD08131 LD08385 LD10854 LD11004 LD11579 LD12132 LD12149 LD13861 LD15529 LD17658 LD19928 LD20161 LD20319 LD20365 LD20502 LD23719 LD24543 LD25969 LD26343 LD27320 LD28847 LD32882 LD35308 LD36077 LD36722 LD37283 LD37416 LD37529 LD41312 LD41576 LD42322 LD42323 LD42366 LD43901 LD44879 LD45723 LD47793 LP06875 LP08706 LP19280 LP21673 RE04487 RE04593 RE06803 RE11116 RE11630 RE17524 RE20820 RE21141 RE23167 RE23524 RE27449 RE29131 RE30620 RE31715 RE32946 RE33856 RE34313 RE35726 RE41683 RE43612 RE43660 RE45492 RE53658 RE54741 RE56554 RE58651 RE58663 RE58828 RE59028 RE62611 RE64946 RE68547 RE71041 RE74301 SD18579 SD19266 SD20065 SD21644 SD24066 SD26523
Other clones	44517 74186 76299 100211 162291 163572 173886 194427 214219.37 214473.47 273043 275404 CK01.73D.D8 CK01.145B.C7 CK01.146A.D4 EK047901 EK058148 EK119412 EK119946 EK265546 EK267933 EK273826 EK300057 EK302913 EP10441 EP11158 FGA011E02 FGM312C03
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010342 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35991
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene. (Butcher et al., 2004) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Fluorescently labelled bacterially expressed Map60 is injected into living embryos and protein behaviour during the rapid syncytial blastoderm divisions (nuclear cycles 10-13) is followed. (Oegema et al., 1997) Cloning and sequencing of Map60 cDNA. Antibodies reveal Map60 is localised to the centrosome in a cell cycle-dependent manner. (Kellogg et al., 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057604 RefSeq (Proteins) • NP_476952 DDBJ / EMBL / GenBank • AA202568 AAB00184 AAF58917 AAL39458 AC006472 AW942030 AY069313 BZ286221 U38248 Entrez Gene - A searchable database of RefSeq genes. • 35991 UniProtKB/TrEMBL • Q7K180 Q24147
Other Crossreferences
Linkouts
	BioGRID - A database of protein and genetic interactions • 61822 DroID - A comprehensive database of gene and protein interactions. • FBgn0010342 DRSC - Results from RNAi screens. • FBgn0010342 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010342 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1825-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010342 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35991 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35991 modMine - Data generated by the modENCODE project. • FBgn0010342 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0236641 FBgn0217951 FBgn0182435 FBgn0176019 FBgn0074881 FBgn0154752 FBgn0130390 FBgn0116230 FBgn0089518
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	CG1825 (Goldstein and Gunawardena, 2000, Ni et al., 2010.12.1) CP60 (Martinez-Campos et al., 2004, Butcher et al., 2004, Terada et al., 2003, Kaltschmidt and Brand, 2002, Marshall, 2003, Megraw et al., 2000, Lee et al., 2001, Lasky, 2000, Fung et al., 2002, Nickerson, 2001, Goldstein and Gunawardena, 2000, Goldstein and Gunawardena, 2000, Sisson et al., 2000, Goldstein and Gunawardena, 2000, Callaini et al., 1999, Johansen et al., 1999, Wasser and Chia, 2000, Brent et al., 2000, Sibon et al., 2000, Kaltschmidt et al., 2000, Kellogg, 1995.10.10, Oegema, 1998, Megraw et al., 1999, Gonzalez et al., 1998, Moritz et al., 1998, Sibon et al., 1997, Oegema et al., 1997, Wakefield and Raff, 1996, Sibon and Theurkauf, 1996, Oegema et al., 1995, Kellogg et al., 1995, Whitfield et al., 1995, Moritz et al., 1995, Oegema et al., 1994, Basto et al., 2006, Georgiev et al., 2008, Somma et al., 2008, Zhang and Megraw, 2007, Basto et al., 2007, Rogers et al., 2008) Cp60 (Gonzalez and Bornens, 2000, de Carcer et al., 2001, ) CP-60 (Matthies et al., 1996) DMAP60 (McKim and Hawley, 1995, Kellogg et al., 1995, Oegema et al., 1994, Schneider and Alberts, 1993, Oegema et al., 1993, Kellogg and Alberts, 1992, Kellogg et al., 1991, ) DMAP-60 (Moritz and Alberts, 1992) Map60 (Altenhein et al., 2006, Buszczak et al., 2007, Bakal et al., 2007, Somma et al., 2008) unnamed (Brinkley et al., 1992)
Name Synonym	Centrosome associated protein 60   Microtubule-associated protein 60
Secondary FlyBase IDs
	FBgn0015027
References ( 76 )
Generate a list of	All references relating to this gene ( 76 )
List References by type	Research paper  ( 36 ) Supplementary material  ( 7 ) Review  ( 8 ) Personal communication to FlyBase  ( 3 ) Abstract  ( 12 ) FlyBase analysis  ( 2 ) Conference report  ( 1 ) DNA/RNA sequence record  ( 2 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 1 )
	Kanesaki et al., 2011, Integr. Biol. (Camb.) 3(11): 1112--1119 Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks. [FBrf0216488] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...