• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Arf79F

General Information
Symbol	Dmel\Arf79F	Species	D. melanogaster
Name	ADP ribosylation factor 79F	Annotation symbol	CG8385
Feature type	protein_coding_gene	FlyBase ID	FBgn0010348
Gene Model Status	Current	Stock availability	12 publicly available
Also Known As	Arf1, ARF-1, Arf
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	80B1-80B1	Sequence location	3L:22,861,479..22,865,331 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene ADP ribosylation factor 79F is referred to in FlyBase by the symbol Dmel\Arf79F (CG8385, FBgn0010348). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity; GTP binding. There is experimental evidence that it is involved in the biological process: regulation of cell shape; cell adhesion; regulation of lipid storage; post-Golgi vesicle-mediated transport. 13 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily, ARF type; Small GTPase superfamily, ARF/SAR type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1624231_s_at completely aligns to an exonic region common to each of the 7 FlyBase-annotated transcript isoforms of Arf79F. Gene sequence location is 3L:22861479..22865331.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN21447 HFA11606
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 80B1-80B1   Limits computationally determined from genome sequence between P{lacW}l(3)j1B10j1B10 and P{lacW}l(3)j2C4j2C4
Experimentally Determined Cytological Location
Cytogenetic map Notes References 79F3-79F5     (Murtagh, 1993.7.21) 79F3-79F3   (determined by in situ hybridisation)   (Lee et al., 1994) 79F3-79F6   (determined by in situ hybridisation)   (Murtagh et al., 1993)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Arf79F for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Arf79F-RA FBtr0078571  NM_168970   1418   182 Arf79F-RB FBtr0078573  NM_057607   1580   182 Arf79F-RC FBtr0078575  NM_168971   1491   182 Arf79F-RE FBtr0078574  NM_168973   1524   182 Arf79F-RF FBtr0112858  NM_001104197   1498   182 Arf79F-RH FBtr0299906  NM_168972   1462   182 Arf79F-RI FBtr0299907  NM_001104198   1459   182
Additional Transcript Data & Comments
Reported size (kB)	1.8 (northern blot) (Murtagh et al., 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Arf79F-PA   FBpp0078222   20.7   182   6.54     NP_730757   AAF51871 Arf79F-PB   FBpp0078224   20.7   182   6.54     NP_476955   AAF51874 Arf79F-PC   FBpp0078226   20.7   182   6.54     NP_730758   AAF51873 Arf79F-PE   FBpp0078225   20.7   182   6.54     NP_730760   AAF51872 Arf79F-PF   FBpp0111771   20.7   182   6.54     NP_001097667   ABW08583 Arf79F-PH   FBpp0289184   20.7   182   6.54     NP_730759   AAN12207 Arf79F-PI   FBpp0289185   20.7   182   6.54     NP_001097668   ABW08584
Additional Polypeptide Data & Comments
Reported size (kDa)	182 (aa) (Murtagh et al., 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Small GTP-binding protein domain (IPR005225) Small GTPase superfamily, ARF/SAR type (IPR006689) Small GTPase superfamily, ARF type (IPR024156)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201461   AA201596   AA202969   AA247049   AA263371   AA264586   AA264610   AA390621   AA391243   AA391508   AA441653   AA540576   AA567918   AA696292   AA696496   AA697122   AA697162   AA697549   AA735401   AA801723   AA802126   AA802173   AA802744   AA820950   AA950400   AE014296 AAF51871   AE014296 AAF51872   AE014296 AAF51873   AE014296 AAF51874   AE014296 AAN12207   AE014296 ABW08583   AE014296 ABW08584   AC005720   AI257337   AI258688   AI259019   AI259870   AI296666   AI297987   AI455036   AI455558   AI945226   AI946581   AY060375 AAL25414   AY231946   BG635867   BG637325   BG661108   BI141760   BI161591   BI162162   BI162271   BI162272   BI165298   BI169519   BI170901   BI171694   BI171819   BI171992   BI173560   BI173734   BI212239   BI214160   BI216551   BI228344   BI228616   BI228819   BI229091   BI230620   BI231457   BI236748   BI237679   BI238726   BI238802   BI241867   BI242044   BI357090   BI357577   BI357877   BI358086   BI358431   BI363034   BI363213   BI364860   BI367139   BI372007   BI372050   BI372099   BI372719   BI481950   BI481976   BI483362   BI483666   BI483965   BI484785   BI485775   BI486079   BI486881   BI566781   BI570402   BI577874   BI584005   BI626115   BI626343   BI628703   BI629562   BI634259   BI638240   BI638251   BI638630   BP541362   BP542790   BP545191   BP546536   BP546585   BP547185   BP547336   BP547349   BP548464   BP552875   BP552876   BP556502   BP557573   BP559149   BX014085   BZ665534   CA804207   CL705830   CO154380   CO155301   CO155389   CO156230   CO156671   CO178870   CO179987   CO181051   CO183847   CO184159   CO184989   CO188432   CO188682   CO189535   CO192252   CO194150   CO194321   CO196241   CO196267   CO196461   CO261826   CO263202   CO269007   CO275537   CO281381   CO286820   CO287723   CO290572   CO293612   CO294208   CO295153   CO310342   CO311093   CO317028   CO320470   CO325511   CO330705   CO332461   CO335780   CO336461   CO337187   CO337327   CO338130   CO340765   CO345489   CZ470655   CZ470656   CZ471876   DN153843   DQ440221   EC058350   EC072177   EC077228   EC078673   EC079628   EC079629   EC079630   EC080915   EC084867   EC088672   EC090640   EC202069   EC204993   EC206788   EC210451   EC212623   EC214142   EC215420   EC216040   EC217109   EC217943   EC219224   EC223364   EC224660   EC224957   EC231243   EC236683   EC241151   EC241402   EC242662   EC247497   EC247555   EC250992   EC252104   EC252235   EC252722   EC263017   EC263446   EC263759   EC264015   EC266796   EC266964   EC267482   EC267806   ES688929   ES691477   ES691507   ES691519   ES691942   ES691954   ES691960   ES691985   EV577322   EV580894   EV581751   EV582432   EV586413   EV592881   GH943426   GH944973   GH946684   GH947523   GH949111   GH950378   GH950588   GH950894   GH950900   GH955688   GH956427   GH958340   GH959672   GH960133   GH963486   GH974058   GH974502   GH977758   GH980868   S62079 AAB27066
UniProtKB/Swiss-Prot	P61209
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference adult stage     (Murtagh et al., 1993)
Additional Descriptive Data
	Arf79F transcripts are detected in RNA isolated from adult heads, legs and bodies. The highest levels are in legs and the lowest levels in heads. (Murtagh et al., 1993)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0010348    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0010348 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0010348 expression level Developmental Stage   Expression Level embryo 00-02hr    10430 embryo 02-04hr    17142 embryo 04-06hr    18918 embryo 06-08hr    17380 embryo 08-10hr    18700 embryo 10-12hr    17039 embryo 12-14hr    23080 embryo 14-16hr    12950 embryo 16-18hr    14366 embryo 18-20hr    9201 embryo 20-22hr    10217 embryo 22-24hr    11974 larva L1    9592 larva L2    15601 larva L3 12hr old    10875 larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6    11361 larva L3 puffstage 7-9    16446 white prepupae new    17283 white prepupae 12hr    10973 white prepupae 24hr    12324 pupae 2d postWPP    10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day    10864 adult female 30day    10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10430) embryo 02-04hr  (17142) embryo 04-06hr  (18918) embryo 06-08hr  (17380) embryo 08-10hr  (18700) embryo 10-12hr  (17039) embryo 12-14hr  (23080) embryo 14-16hr  (12950) embryo 16-18hr  (14366) embryo 18-20hr  (9201) embryo 20-22hr  (10217) embryo 22-24hr  (11974) larva L1  (9592) larva L2  (15601) larva L3 12hr old  (10875) larva L3 puffstage 1-2  (9367) larva L3 puffstage 3-6  (11361) larva L3 puffstage 7-9  (16446) white prepupae new  (17283) white prepupae 12hr  (10973) white prepupae 24hr  (12324) pupae 2d postWPP  (10190) pupae 3d postWPP  (6190) pupae 4d postWPP  (4239) adult male 01day  (6393) adult male 05day  (5837) adult male 30day  (5392) adult female 01day  (6415) adult female 05day  (10864) adult female 30day  (10261) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10430) embryo 02-04hr  (17142) embryo 04-06hr  (18918) embryo 06-08hr  (17380) embryo 08-10hr  (18700) embryo 10-12hr  (17039) embryo 12-14hr  (23080) embryo 14-16hr  (12950) embryo 16-18hr  (14366) embryo 18-20hr  (9201) embryo 20-22hr  (10217) embryo 22-24hr  (11974) larva L1  (9592) larva L2  (15601) larva L3 12hr old  (10875) larva L3 puffstage 1-2  (9367) larva L3 puffstage 3-6  (11361) larva L3 puffstage 7-9  (16446) white prepupae new  (17283) white prepupae 12hr  (10973) white prepupae 24hr  (12324) pupae 2d postWPP  (10190) pupae 3d postWPP  (6190) pupae 4d postWPP  (4239) adult male 01day  (6393) adult male 05day  (5837) adult male 30day  (5392) adult female 01day  (6415) adult female 05day  (10864) adult female 30day  (10261) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10430 embryo 02-04hr  (17142) embryo 04-06hr  (18918) embryo 06-08hr  (17380) embryo 08-10hr  (18700) embryo 10-12hr  (17039) embryo 12-14hr  (23080) embryo 14-16hr  (12950) embryo 16-18hr  (14366) embryo 18-20hr    9201 embryo 20-22hr  10217 embryo 22-24hr  (11974) larva L1    9592 larva L2  (15601) larva L3 12hr old  (10875) larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6  (11361) larva L3 puffstage 7-9  (16446) white prepupae new  (17283) white prepupae 12hr  (10973) white prepupae 24hr  (12324) pupae 2d postWPP  10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day  (10864) adult female 30day  10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10430 embryo 02-04hr    17142 embryo 04-06hr    18918 embryo 06-08hr    17380 embryo 08-10hr    18700 embryo 10-12hr    17039 embryo 12-14hr    23080 embryo 14-16hr    12950 embryo 16-18hr    14366 embryo 18-20hr    9201 embryo 20-22hr    10217 embryo 22-24hr    11974 larva L1    9592 larva L2    15601 larva L3 12hr old    10875 larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6    11361 larva L3 puffstage 7-9    16446 white prepupae new    17283 white prepupae 12hr    10973 white prepupae 24hr    12324 pupae 2d postWPP    10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day    10864 adult female 30day    10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0010348 expression level Developmental Stage   Expression Level embryo 00-02hr    10430 embryo 02-04hr    17142 embryo 04-06hr    18918 embryo 06-08hr    17380 embryo 08-10hr    18700 embryo 10-12hr    17039 embryo 12-14hr    23080 embryo 14-16hr    12950 embryo 16-18hr    14366 embryo 18-20hr    9201 embryo 20-22hr    10217 embryo 22-24hr    11974 larva L1    9592 larva L2    15601 larva L3 12hr old    10875 larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6    11361 larva L3 puffstage 7-9    16446 white prepupae new    17283 white prepupae 12hr    10973 white prepupae 24hr    12324 pupae 2d postWPP    10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day    10864 adult female 30day    10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (10430) embryo 02-04hr  (17142) embryo 04-06hr  (18918) embryo 06-08hr  (17380) embryo 08-10hr  (18700) embryo 10-12hr  (17039) embryo 12-14hr  (23080) embryo 14-16hr  (12950) embryo 16-18hr  (14366) embryo 18-20hr  (9201) embryo 20-22hr  (10217) embryo 22-24hr  (11974) larva L1  (9592) larva L2  (15601) larva L3 12hr old  (10875) larva L3 puffstage 1-2  (9367) larva L3 puffstage 3-6  (11361) larva L3 puffstage 7-9  (16446) white prepupae new  (17283) white prepupae 12hr  (10973) white prepupae 24hr  (12324) pupae 2d postWPP  (10190) pupae 3d postWPP  (6190) pupae 4d postWPP  (4239) adult male 01day  (6393) adult male 05day  (5837) adult male 30day  (5392) adult female 01day  (6415) adult female 05day  (10864) adult female 30day  (10261) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (10430) embryo 02-04hr  (17142) embryo 04-06hr  (18918) embryo 06-08hr  (17380) embryo 08-10hr  (18700) embryo 10-12hr  (17039) embryo 12-14hr  (23080) embryo 14-16hr  (12950) embryo 16-18hr  (14366) embryo 18-20hr  (9201) embryo 20-22hr  (10217) embryo 22-24hr  (11974) larva L1  (9592) larva L2  (15601) larva L3 12hr old  (10875) larva L3 puffstage 1-2  (9367) larva L3 puffstage 3-6  (11361) larva L3 puffstage 7-9  (16446) white prepupae new  (17283) white prepupae 12hr  (10973) white prepupae 24hr  (12324) pupae 2d postWPP  (10190) pupae 3d postWPP  (6190) pupae 4d postWPP  (4239) adult male 01day  (6393) adult male 05day  (5837) adult male 30day  (5392) adult female 01day  (6415) adult female 05day  (10864) adult female 30day  (10261) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  10430 embryo 02-04hr  17142 embryo 04-06hr  18918 embryo 06-08hr  17380 embryo 08-10hr  18700 embryo 10-12hr  17039 embryo 12-14hr  (23080) embryo 14-16hr  12950 embryo 16-18hr  14366 embryo 18-20hr    9201 embryo 20-22hr  10217 embryo 22-24hr  11974 larva L1    9592 larva L2  15601 larva L3 12hr old  10875 larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6  11361 larva L3 puffstage 7-9  16446 white prepupae new  17283 white prepupae 12hr  10973 white prepupae 24hr  12324 pupae 2d postWPP  10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day  10864 adult female 30day  10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    10430 embryo 02-04hr    17142 embryo 04-06hr    18918 embryo 06-08hr    17380 embryo 08-10hr    18700 embryo 10-12hr    17039 embryo 12-14hr    23080 embryo 14-16hr    12950 embryo 16-18hr    14366 embryo 18-20hr    9201 embryo 20-22hr    10217 embryo 22-24hr    11974 larva L1    9592 larva L2    15601 larva L3 12hr old    10875 larva L3 puffstage 1-2    9367 larva L3 puffstage 3-6    11361 larva L3 puffstage 7-9    16446 white prepupae new    17283 white prepupae 12hr    10973 white prepupae 24hr    12324 pupae 2d postWPP    10190 pupae 3d postWPP    6190 pupae 4d postWPP    4239 adult male 01day    6393 adult male 05day    5837 adult male 30day    5392 adult female 01day    6415 adult female 05day    10864 adult female 30day    10261 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0010348    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0010348 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0010348 expression level Tissue   Expression Level Larval Central Nervous System    1554.275 Larval Midgut    1892.6 Larval Hindgut    1792.6 Larval Malpighian Tubules    2103.3 Larval Fat Body    1893.9 Larval Salivary Gland    3894.7 Larval Trachea    1617.625 Larval Carcass    1487.25 Adult Head    1216.3 Adult Eye    1254.025 Adult Brain    1140 Adult Thoracic-Abdominal Ganglion    1004.1 Adult Crop    1430.3 Adult Midgut    1532.1 Adult Hindgut    1177.9 Adult Malpighian Tubules    2215.3 Adult Fat Body    1870.1 Adult Salivary Gland    2815.2 Adult Heart    1723.225 Adult VirginFemale Spermatheca    1958 Adult InseminatedFemale Spermatheca    2157.1 Adult Ovary    1377.3 Adult Testis    448.4 Adult Male Accessory Gland    2626 Adult Carcass    1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1554.275) Larval Midgut  (1892.6) Larval Hindgut  (1792.6) Larval Malpighian Tubules  (2103.3) Larval Fat Body  (1893.9) Larval Salivary Gland  (3894.7) Larval Trachea  (1617.625) Larval Carcass  (1487.25) Adult Head  (1216.3) Adult Eye  (1254.025) Adult Brain  (1140) Adult Thoracic-Abdominal Ganglion  (1004.1) Adult Crop  (1430.3) Adult Midgut  (1532.1) Adult Hindgut  (1177.9) Adult Malpighian Tubules  (2215.3) Adult Fat Body  (1870.1) Adult Salivary Gland  (2815.2) Adult Heart  (1723.225) Adult VirginFemale Spermatheca  (1958) Adult InseminatedFemale Spermatheca  (2157.1) Adult Ovary  (1377.3) Adult Testis    448.4 Adult Male Accessory Gland  (2626) Adult Carcass  (1003.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1554.275) Larval Midgut  (1892.6) Larval Hindgut  (1792.6) Larval Malpighian Tubules  (2103.3) Larval Fat Body  (1893.9) Larval Salivary Gland  (3894.7) Larval Trachea  (1617.625) Larval Carcass  (1487.25) Adult Head  (1216.3) Adult Eye  (1254.025) Adult Brain  (1140) Adult Thoracic-Abdominal Ganglion  1004.1 Adult Crop  (1430.3) Adult Midgut  (1532.1) Adult Hindgut  (1177.9) Adult Malpighian Tubules  (2215.3) Adult Fat Body  (1870.1) Adult Salivary Gland  (2815.2) Adult Heart  (1723.225) Adult VirginFemale Spermatheca  (1958) Adult InseminatedFemale Spermatheca  (2157.1) Adult Ovary  (1377.3) Adult Testis    448.4 Adult Male Accessory Gland  (2626) Adult Carcass  1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1554.275 Larval Midgut    1892.6 Larval Hindgut    1792.6 Larval Malpighian Tubules    2103.3 Larval Fat Body    1893.9 Larval Salivary Gland    3894.7 Larval Trachea    1617.625 Larval Carcass    1487.25 Adult Head    1216.3 Adult Eye    1254.025 Adult Brain    1140 Adult Thoracic-Abdominal Ganglion    1004.1 Adult Crop    1430.3 Adult Midgut    1532.1 Adult Hindgut    1177.9 Adult Malpighian Tubules    2215.3 Adult Fat Body    1870.1 Adult Salivary Gland    2815.2 Adult Heart    1723.225 Adult VirginFemale Spermatheca    1958 Adult InseminatedFemale Spermatheca    2157.1 Adult Ovary    1377.3 Adult Testis    448.4 Adult Male Accessory Gland    2626 Adult Carcass    1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0010348 expression level Tissue   Expression Level Larval Central Nervous System    1554.275 Larval Midgut    1892.6 Larval Hindgut    1792.6 Larval Malpighian Tubules    2103.3 Larval Fat Body    1893.9 Larval Salivary Gland    3894.7 Larval Trachea    1617.625 Larval Carcass    1487.25 Adult Head    1216.3 Adult Eye    1254.025 Adult Brain    1140 Adult Thoracic-Abdominal Ganglion    1004.1 Adult Crop    1430.3 Adult Midgut    1532.1 Adult Hindgut    1177.9 Adult Malpighian Tubules    2215.3 Adult Fat Body    1870.1 Adult Salivary Gland    2815.2 Adult Heart    1723.225 Adult VirginFemale Spermatheca    1958 Adult InseminatedFemale Spermatheca    2157.1 Adult Ovary    1377.3 Adult Testis    448.4 Adult Male Accessory Gland    2626 Adult Carcass    1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1554.275) Larval Midgut  (1892.6) Larval Hindgut  (1792.6) Larval Malpighian Tubules  (2103.3) Larval Fat Body  (1893.9) Larval Salivary Gland  (3894.7) Larval Trachea  (1617.625) Larval Carcass  (1487.25) Adult Head  (1216.3) Adult Eye  (1254.025) Adult Brain  (1140) Adult Thoracic-Abdominal Ganglion  (1004.1) Adult Crop  (1430.3) Adult Midgut  (1532.1) Adult Hindgut  (1177.9) Adult Malpighian Tubules  (2215.3) Adult Fat Body  (1870.1) Adult Salivary Gland  (2815.2) Adult Heart  (1723.225) Adult VirginFemale Spermatheca  (1958) Adult InseminatedFemale Spermatheca  (2157.1) Adult Ovary  (1377.3) Adult Testis    448.4 Adult Male Accessory Gland  (2626) Adult Carcass  (1003.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1554.275 Larval Midgut  (1892.6) Larval Hindgut  (1792.6) Larval Malpighian Tubules  (2103.3) Larval Fat Body  (1893.9) Larval Salivary Gland  (3894.7) Larval Trachea  1617.625 Larval Carcass  1487.25 Adult Head  1216.3 Adult Eye  1254.025 Adult Brain  1140 Adult Thoracic-Abdominal Ganglion  1004.1 Adult Crop  1430.3 Adult Midgut  1532.1 Adult Hindgut  1177.9 Adult Malpighian Tubules  (2215.3) Adult Fat Body  (1870.1) Adult Salivary Gland  (2815.2) Adult Heart  (1723.225) Adult VirginFemale Spermatheca  (1958) Adult InseminatedFemale Spermatheca  (2157.1) Adult Ovary  1377.3 Adult Testis    448.4 Adult Male Accessory Gland  (2626) Adult Carcass  1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1554.275 Larval Midgut    1892.6 Larval Hindgut    1792.6 Larval Malpighian Tubules    2103.3 Larval Fat Body    1893.9 Larval Salivary Gland    3894.7 Larval Trachea    1617.625 Larval Carcass    1487.25 Adult Head    1216.3 Adult Eye    1254.025 Adult Brain    1140 Adult Thoracic-Abdominal Ganglion    1004.1 Adult Crop    1430.3 Adult Midgut    1532.1 Adult Hindgut    1177.9 Adult Malpighian Tubules    2215.3 Adult Fat Body    1870.1 Adult Salivary Gland    2815.2 Adult Heart    1723.225 Adult VirginFemale Spermatheca    1958 Adult InseminatedFemale Spermatheca    2157.1 Adult Ovary    1377.3 Adult Testis    448.4 Adult Male Accessory Gland    2626 Adult Carcass    1003.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1216.3   NA  Eye    1254.025   NA  Brain    1140   1554.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1004.1   NA  Crop    1430.3   1892.6  Midgut    1532.1   1792.6  Hindgut    1177.9   2103.3  Malpighian Tubules    2215.3   1893.9  Fat Body    1870.1   3894.7  Salivary Gland    2815.2   NA  Heart    1723.225   1617.625  Trachea    NA   NA  VirginFemale Spermatheca    1958   NA  InseminatedFemale Spermatheca    2157.1   NA  Ovary    1377.3   NA  Testis    448.4   NA  Male Accessory Gland    2626   1487.25  Carcass    1003.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010348 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8385-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 Arf79FGD12522 viable Arf79FEY08473 Sterility Allele fertile Arf79FEY08473 Phenotype manifest in Allele
Classical Alleles ( 10 )
For All Classical Alleles Show
Allele of Arf79F Class Mutagen Stocks Known lesion Arf79F5-SZ-3080 1 -- Arf79F5-SZ-3476 1 -- Arf79FC005 1 -- Arf79Fd00896 P-element activity 1 -- Arf79FEY00502 1 -- Arf79FEY00996 P-element activity 1 -- Arf79FEY08473 P-element activity 1 -- Arf79FNP0204 1 -- Arf79FNP0567 1 -- Arf79Fc06390 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Arf79F Class Mutagen Stocks Known lesion Arf79FGD12522 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Arf79FJF01809 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Arf79FKK101396 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6139 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12522} NA P{KK101396} NA P{TRiP.JF01809} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}Arf79FEY00502 NA P{EPgy2}Arf79FEY00996 NA P{EPgy2}Arf79FEY08473 NA P{Mae-UAS.6.11}B0929a NA P{XP}Arf79Fd00896 NA miscellaneous insertions P{RS5}Arf79F5-SZ-3080 NA P{RS5}Arf79F5-SZ-3476 NA PBac{3HPy+}Arf79FC005 NA PBac{PB}Arf79Fc06390 NA insertion of enhancer trap binary system P{GawB}Arf79FNP0204 No P{GawB}Arf79FNP0567 No
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cell adhesion inferred from mutant phenotype (Kiger et al., 2003) post-Golgi vesicle-mediated transport inferred from mutant phenotype (Kametaka et al., 2010) regulation of cell shape inferred from mutant phenotype (Kiger et al., 2003) regulation of lipid storage inferred from direct assay (Beller et al., 2008)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 8 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from sequence or structural similarity (Jekely, 2003) GTP binding inferred from sequence or structural similarity with mouse Arf2 (FlyBase, 1992-) non-traceable author statement (Murtagh, 1993.7.21)
Biological Process
CV term Evidence References
endosome transport traceable author statement (Stimson and Ramaswami, 1999) neurotransmitter secretion traceable author statement (Lloyd et al., 2000) protein ADP-ribosylation inferred from sequence or structural similarity with UniProtKB:P51643 (FlyBase, 1992-) non-traceable author statement (Murtagh, 1993.7.21) small GTPase mediated signal transduction inferred from electronic annotation with InterPro:IPR024156 (FlyBase Curators et al., 2004-) synaptic vesicle endocytosis traceable author statement (Lloyd et al., 2000)
Cellular Component
CV term Evidence References
intracellular inferred from electronic annotation with InterPro:IPR024156 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Arf79F allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65734 DroID - A comprehensive database of gene and protein interactions. • FBgn0010348 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40506
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23441 Dere\GG13164 Dgri\GH14762 Dmoj\GI11864 Dper\GL25178 Dpse\GA21036 Dsec\GM22073 Dsim\GD12049 Dvir\GJ13559 Dwil\GK20496 Dyak\GE19486
Curated drosophilid orthologs	Dpse\GA21036
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007065-PA Aedes aegypti (mosquito) AGAP012014-PA Anopheles gambiae (mosquito) XP_392990.2 Apis mellifera (honey bee) XP_001944342.1 Acyrthosiphon pisum (pea aphid) At3g62290.1 Arabidopsis thaliana (wall cress) 36333 Batrachochytrium dendrobatidis (chytrid fungus) 263946 Branchiostoma floridae (lancelet) 268541 Branchiostoma floridae (lancelet) XP_001902862.1 Brugia malayi (roundworm nematode) BGIBMGA005347-PA Bombyx mori (silk worm) ENSBTAP00000010159 Bos taurus (bovine) CAL0003401 Candida albicans (a form of yeast) CBP02198 Caenorhabditis briggsae (nematode) CE00696 Caenorhabditis elegans (worm) ENSCAFP00000012918 Canis familiaris (dog) CAGL0J09064g Candida glabrata (haploid yeast) Chro.30115 Cryptosporidium hominis (obligate parasite) ENSCINP00000009265 Ciona intestinalis (sea squirt) CMQ074C Cyanidioschyzon merolae (red alga) cn07155 Cryptococcus neoformans (yeast-like fungus) cgd3_860 Cryptosporidium parvum (protozoan parasite) CPIJ004239 Culex pipens (mosquito) ENSCPOP00000020498 Cavia porcellus (guinea pig) 183074 Chlamidomonas reinhardtii (green alga) 186126 Chlamidomonas reinhardtii (green alga) RP22588 Caenorhabditis remanei (nematode) ENSCSAVP00000011935 Ciona savignyi (sedentary tunicate) 151740 Capitella spl (polychaete worm) DDB0191101 Dictyostelium discoideum (amoeba) DEHA2E02002g Debaryomyces Hansenii (yeast) 231341 Daphnia pulex (daphnia) ENSDARP00000004127 Danio rerio (zebra fish) ENSECAP00000006246 Equus caballus (horse) XP_654041 Entamoeba histolytica (anaerobic protozoan) XP_656677 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005732 Gymnopilus aculeatus (mushroom) ENSGALP00000038376 Gallus gallus (chicken) GL50803_7789 Giardia lamblia (flagellated protozoan) 186077 Hypsipyla robusta (cedar shoot borer) ENSP00000355714 Homo sapiens (human) ISCW022927-PA Ixodes scapularis (deer tick) KLLA0F05225g Kluyveromyces lactis (yeast) 236204 Lottia gigantea (owl limpet) LmjF31.2790 Leishmania major (virus) 35269 Monocosta brevicollis (choanoflagellate) ENSMODP00000034210 Monodelphis domestica (gray opossum) ENSMMUP00000003743 Macaca mulatta (rhesus monkey) ENSMUSP00000079905 Mus musculus (house mouse) 242285 Nematostella vectensis (starlet anemone) XP_001599092.1 Nasonia vitripennis (wasp) ENSORLP00000017696 Oryzias latipes (japanese killifish) LOC_Os01g59790.1 Oryza sativa (asian rice) LOC_Os05g41060.1 Oryza sativa (asian rice) 20505 Ostreococcus tauri (green alga) PF10_0203 Plasmodium falciparum (protozoal parasite) PHUM002663-PA Pediculus humanus (human body louse) PP08642 Pristionchus pacificus (nematode) 107867 Physcomitrella patens (moss) 164517 Physcomitrella patens (moss) 193635 Physcomitrella patens (moss) 211063 Physcomitrella patens (moss) ENSPPYP00000000146 Pongo pygmaeus (orangutan) 71244 Phytophthora ramorum (sudden oak death pathogen) 71245 Phytophthora ramorum (sudden oak death pathogen) 108374 Phytophthora sojae (root rot pathogen) 111835 Phytophthora sojae (root rot pathogen) 570684 Populus trichocarpa (black cottonwood) 644880 Populus trichocarpa (black cottonwood) 664306 Populus trichocarpa (black cottonwood) 671531 Populus trichocarpa (black cottonwood) 744433 Populus trichocarpa (black cottonwood) ENSPTRP00000003488 Pan troglodytes (chimpanzee) PVX_001905 Plasmodium vivax (protozoal parasite) ENSRNOP00000047263 Rattus norvegicus (norway rat) 4768438 Sorghum bicolor (sorghum) YDL137W Saccharomyces cerevisiae (budding yeast) YDL192W Saccharomyces cerevisiae (budding yeast) Smp_032180 Schistosoma mansoni (trematode parasite) SPBC4F6.18c Schizosaccharomyces pombe (fission yeast) XP_791037.1 Strongylocentrotus purpuratus (purple sea urchin) 63238 Trichoplax adhaerens (metazoa) TA12110 Theileria annulata (apicomplexan parasite) XP_968387.1 Tribolium castaneum (red flour beetle) Tc00.1047053508415.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508415.50 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053510755.50 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053510755.60 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000004445 Tetraodon nigroviridis (green spotted pufferfish) TP02_0245 Theileria parva (parasitic protozoan) 39299 Thalassiosira pseudonana (marine diatom) ENSTRUP00000018486 Takifugu rubripes (pufferfish Takifugu) 120.m00106 Tetrahymena thermophila (ciliate protozoa) 85294.m00057 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000030434 Xenopus tropicalis (frog) YALI0F02167g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16175 NV18390 LH12678 ISCW022927 FBgn0236827 FBgn0222493 FBgn0200783 FBgn0183788 FBgn0176944 JGI_V11_231341 FBgn0081024 FBgn0162762 FBgn0134622 FBgn0122238 FBgn0105436 FBgn0100435 CPIJ004239 BGIBMGA005347 ACYPI004224 GB10675 AGAP012014 AAEL007065 PHUM523570 GLEAN_12647
Stocks & Reagents
Stocks Listed in FlyBase ( 12 )
Bloomington	29538 y1 v1; P{TRiP.JF01809}attP2 15054 y1 w67c23; P{EPgy2}Arf79FEY00996 19877 y1 w67c23; P{EPgy2}Arf79FEY08473 15466 y1 w67c23; P{EPgy2}Arf79FEY00502/TM3, Sb1 Ser1 16251 y1 w1118; PBac{3HPy+}Arf79FC005/TM3, Sb1 Ser1
Harvard	- P{XP}Arf79Fd00896
Kyoto	125877 w1118; P{RS5}Arf79F5-SZ-3080 126084 w1118; P{RS5}Arf79F5-SZ-3476 112223 w*; P{GawB}Arf79FNP0567 / CyO; TM3, Ser1 103556 y* w*; P{GawB}Arf79FNP0204 / TM6, P{UAS-lacZ.UW23-1}UW23-1
VDRC	v103572 P{KK101396}VIE-260B v23082 w1118; P{GD12522}v23082
Genomic Clones ( 1 )
	BACR48E05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 224 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24904
Other clones	yak-em_Arf102F
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM03405 GM03891 GM03967 GM05474 GM06245 GM07784 GM09133 GM09230 HL01995 HL02755 LD03384 LD04479 LD04675 LD05401 LD06187 LD06484 LD08225 LD08252 LD09674 LD10443 LD10536 LD14794 LD16655 LD20306 LD21250 LD28940 LP01937 LP02339 LP03383 LP05665 LP10647 LP12489 RE01554 RE05158 RE10717 RE12513 RE13523 RE13677 RE13907 RE14336 RE16503 RE16826 RE17288 RE19882 RE21927 RE23728 RE25869 RE26213 RE26465 RE26801 RE32856 RE33951 RE35246 RE39058 RE39260 RE41878 RE43446 RE44101 RE44481 RE44757 RE45201 RE47735 RE47972 RE50051 RE52838 RE56467 RE57610 RE58829 RE59767 RE64580 RE64611 RE66243 RE66585 RE66947 RE67939 RE69120 RE69452 RE70361 RE71633 RH02721 RH22755 RH36524 RH37688 RH57224 RH58449 RH66661 RH67039 SD13370 SD15245 SD15674 SD20476 SD20493 SD20973
Other clones	15072 36526 42384 60520 74322 78797 79041 79479 83827 98473 100594 108682 124502 125364 162793 179476 179653 193108 214281.41 214405.63 214509.45 273515 276722 523640 524804 527275 528113 542723 557884 568823 569979 bs10d07 bs28a09 CK01.34D.H2 CK01.49B.F4 CK01.54D.H6 CK01.61B.E8 CK01.73B.A10 CK01.95C.C4 CK01.104D.D6 CK01.113A.D12 CK01.115D.F12 Dmel_dig_012324_0701_3434 Dmel_dig_016280_0703_2522 Dmel_dig_019020_0603_2490 Dmel_dig_019855_0631_0772 Dmel_neb_013971_0577_0714 Dmel_neb_014811_0151_1227 EC00720 EC13390 EC26524 EC27247 EC29048 EC33432 EC37524 EC38043 EK002336 EK002536 EK004656 EK010952 EK040152 EK041454 EK044463 EK057826 EK063952 EK066602 EK074342 EK080147 EK087747 EK093306 EK117851 EK157020 EK196663 EK203838 EK206328 EK208749 EK221257 EK223349 EK266745 EK285611 EK295962 EK303526 EN04022 EN05808 EN05947 EN07619 EN08544 EN11163 EN12563 EN14012 EN14301 EN16019 EP11312 EP22144 ESG0112c.B21_C12 FGB002C09 FGC017A02 FGC029H12 FGH107D12 FGH108A01 FGH114C11 FGH115H06 FGH116A07 FGH128A10 FGM221C08 FGM303H06 FGM310A10 FGM319C03 RE01064 RE01634 RP004036858 RP004079288 RP004092836 RP004164008 RP004164074 RP004169011 RP004175871 RP004187524 RP004209184 RP004217910 RP004234042 RP004236755 RP004252230 RP004280196 RP004362266 RP004370969 RP004513943 RP004548650 RP004553515
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010348 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40506
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Arf79F CG8385 (Worley, 1999.11)
Source for database merge of
Additional comments
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become round and detached. Kc167 cells are unaffected. (Kiger et al., 2003) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes. (Kliman and Eyre-Walker, 1998) Arf79F is thought to have discordant intron with its human gene homolog. The discordance does not arise from sequence alignment ambiguities and is not attributable to errors. Results suggest intron 'sliding' may contribute to the diversity of intron positions. (Stoltzfus et al., 1997) Arf79F is isolated and cloned. (Murtagh et al., 1993) Encodes a small GTP-binding protein of the ADP-ribosymation factor family.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057607 NM_168970 NM_168971 NM_168972 NM_168973 NM_001104197 NM_001104198 RefSeq (Proteins) • NP_476955 NP_730757 NP_730758 NP_730759 NP_730760 NP_001097667 NP_001097668 DDBJ / EMBL / GenBank • AA697122 AA820950 AAB27066 AAF51871 AAF51872 AAF51873 AAF51874 AAL25414 AAN12207 ABW08583 ABW08584 AC005720 AI455558 AI945226 AY060375 BZ665534 CL705830 CZ470655 CZ470656 CZ471876 S62079 Entrez Gene - A searchable database of RefSeq genes. • 40506 UniProtKB/Swiss-Prot • P61209
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Small GTP-binding protein domain (IPR005225) Small GTPase superfamily, ARF/SAR type (IPR006689) Small GTPase superfamily, ARF type (IPR024156)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65734 DroID - A comprehensive database of gene and protein interactions. • FBgn0010348 DRSC - Results from RNAi screens. • FBgn0010348 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010348 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8385-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010348 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40506 InParanoid A subset of ortholog calls from InParanoid. • AAEL007065-PA Aedes aegypti (mosquito) AGAP012014-PA Anopheles gambiae (mosquito) XP_392990.2 Apis mellifera (honey bee) XP_001944342.1 Acyrthosiphon pisum (pea aphid) At3g62290.1 Arabidopsis thaliana (wall cress) 36333 Batrachochytrium dendrobatidis (chytrid fungus) 263946 Branchiostoma floridae (lancelet) 268541 Branchiostoma floridae (lancelet) XP_001902862.1 Brugia malayi (roundworm nematode) BGIBMGA005347-PA Bombyx mori (silk worm) ENSBTAP00000010159 Bos taurus (bovine) CAL0003401 Candida albicans (a form of yeast) CBP02198 Caenorhabditis briggsae (nematode) CE00696 Caenorhabditis elegans (worm) ENSCAFP00000012918 Canis familiaris (dog) CAGL0J09064g Candida glabrata (haploid yeast) Chro.30115 Cryptosporidium hominis (obligate parasite) ENSCINP00000009265 Ciona intestinalis (sea squirt) CMQ074C Cyanidioschyzon merolae (red alga) cn07155 Cryptococcus neoformans (yeast-like fungus) cgd3_860 Cryptosporidium parvum (protozoan parasite) CPIJ004239 Culex pipens (mosquito) ENSCPOP00000020498 Cavia porcellus (guinea pig) 183074 Chlamidomonas reinhardtii (green alga) 186126 Chlamidomonas reinhardtii (green alga) RP22588 Caenorhabditis remanei (nematode) ENSCSAVP00000011935 Ciona savignyi (sedentary tunicate) 151740 Capitella spl (polychaete worm) DDB0191101 Dictyostelium discoideum (amoeba) DEHA2E02002g Debaryomyces Hansenii (yeast) 231341 Daphnia pulex (daphnia) ENSDARP00000004127 Danio rerio (zebra fish) ENSECAP00000006246 Equus caballus (horse) XP_654041 Entamoeba histolytica (anaerobic protozoan) XP_656677 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005732 Gymnopilus aculeatus (mushroom) ENSGALP00000038376 Gallus gallus (chicken) GL50803_7789 Giardia lamblia (flagellated protozoan) 186077 Hypsipyla robusta (cedar shoot borer) ENSP00000355714 Homo sapiens (human) ISCW022927-PA Ixodes scapularis (deer tick) KLLA0F05225g Kluyveromyces lactis (yeast) 236204 Lottia gigantea (owl limpet) LmjF31.2790 Leishmania major (virus) 35269 Monocosta brevicollis (choanoflagellate) ENSMODP00000034210 Monodelphis domestica (gray opossum) ENSMMUP00000003743 Macaca mulatta (rhesus monkey) ENSMUSP00000079905 Mus musculus (house mouse) 242285 Nematostella vectensis (starlet anemone) XP_001599092.1 Nasonia vitripennis (wasp) ENSORLP00000017696 Oryzias latipes (japanese killifish) LOC_Os01g59790.1 Oryza sativa (asian rice) LOC_Os05g41060.1 Oryza sativa (asian rice) 20505 Ostreococcus tauri (green alga) PF10_0203 Plasmodium falciparum (protozoal parasite) PHUM002663-PA Pediculus humanus (human body louse) PP08642 Pristionchus pacificus (nematode) 107867 Physcomitrella patens (moss) 164517 Physcomitrella patens (moss) 193635 Physcomitrella patens (moss) 211063 Physcomitrella patens (moss) ENSPPYP00000000146 Pongo pygmaeus (orangutan) 71244 Phytophthora ramorum (sudden oak death pathogen) 71245 Phytophthora ramorum (sudden oak death pathogen) 108374 Phytophthora sojae (root rot pathogen) 111835 Phytophthora sojae (root rot pathogen) 570684 Populus trichocarpa (black cottonwood) 644880 Populus trichocarpa (black cottonwood) 664306 Populus trichocarpa (black cottonwood) 671531 Populus trichocarpa (black cottonwood) 744433 Populus trichocarpa (black cottonwood) ENSPTRP00000003488 Pan troglodytes (chimpanzee) PVX_001905 Plasmodium vivax (protozoal parasite) ENSRNOP00000047263 Rattus norvegicus (norway rat) 4768438 Sorghum bicolor (sorghum) YDL137W Saccharomyces cerevisiae (budding yeast) YDL192W Saccharomyces cerevisiae (budding yeast) Smp_032180 Schistosoma mansoni (trematode parasite) SPBC4F6.18c Schizosaccharomyces pombe (fission yeast) XP_791037.1 Strongylocentrotus purpuratus (purple sea urchin) 63238 Trichoplax adhaerens (metazoa) TA12110 Theileria annulata (apicomplexan parasite) XP_968387.1 Tribolium castaneum (red flour beetle) Tc00.1047053508415.40 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053508415.50 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053510755.50 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053510755.60 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000004445 Tetraodon nigroviridis (green spotted pufferfish) TP02_0245 Theileria parva (parasitic protozoan) 39299 Thalassiosira pseudonana (marine diatom) ENSTRUP00000018486 Takifugu rubripes (pufferfish Takifugu) 120.m00106 Tetrahymena thermophila (ciliate protozoa) 85294.m00057 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000030434 Xenopus tropicalis (frog) YALI0F02167g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40506 modMine - Data generated by the modENCODE project. • FBgn0010348 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16175 NV18390 LH12678 ISCW022927 FBgn0236827 FBgn0222493 FBgn0200783 FBgn0183788 FBgn0176944 JGI_V11_231341 FBgn0081024 FBgn0162762 FBgn0134622 FBgn0122238 FBgn0105436 FBgn0100435 CPIJ004239 BGIBMGA005347 ACYPI004224 GB10675 AGAP012014 AAEL007065 PHUM523570 GLEAN_12647
Synonyms & Secondary IDs ( 16 )
Reported As
Symbol Synonym	Arf (Kakihara et al., 2007, Li et al., 2010) ARF-1 (Tycowski and Steitz, 2001, Renalier et al., 1996) Arf1 (Boman and Kahn, 1995, Beller et al., 2008, Gupta et al., 2009, Li et al., 2010) ARF1 (Murtagh et al., 1993, Beller et al., 2008, Kametaka et al., 2010) ARF1_DROME (Storm and Sonnhammer, 2003) Arf79F (Bakal et al., 2007, Grieder et al., 2007, Guo et al., 2008, Sinka et al., 2008, Beller et al., 2008, Dorer et al., 2006, Asensio et al., 2010, Shao et al., 2010, Kametaka et al., 2010, Southon et al., 2011) CG8385 (Huang et al., 2005, Grieder et al., 2007, Sinka et al., 2008, Dorer et al., 2006, Keleman et al., 2009.8.5, Perkins et al., 2009, Cammarato et al., 2011) Darf1   dArf1 (Kametaka et al., 2010) dARF79F (Kametaka et al., 2010) dARFI (Lee et al., 1994) Dm Arf79F (Jekely, 2003) unnamed (Lloyd et al., 2000)
Name Synonym	ADP-ribosylation factor 1 (Murtagh, 1993.7.21) ADP ribosylation factor 79F (Cammarato et al., 2011) ADP ribosylation factor at 79F (Beller et al., 2008)
Secondary FlyBase IDs
References ( 56 )
Generate a list of	All references relating to this gene ( 56 )
List References by type	Research paper  ( 24 ) Supplementary material  ( 8 ) Review  ( 4 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 1 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 7 )
	Southon et al., 2011, Int. J. Biochem. & Cell Biol. 43(1): 146--153 The ADP-ribosylation factor 1 (Arf1) is involved in regulating copper uptake. [FBrf0212662] Asensio et al., 2010, J. Cell Biol. 191(6): 1173--1187 RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. [FBrf0212515] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Kametaka et al., 2010, J. Cell Sci. 123(3): 460--471 Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster. [FBrf0209912] Li et al., 2010, J. Biol. Chem. 285(26): 19705--19709 Regulation of mTORC1 by the Rab and Arf GTPases. [FBrf0211071] Shao et al., 2010, PLoS ONE 5(4): e9938 A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. [FBrf0210449] Willis et al., 2010, J. Insect Sci. 10: 66 Microarray Analysis of Juvenile Hormone Response in Drosophila melanogaster S2 cells. [FBrf0211402] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...