dTAFII80, Taf80, TAFII80, TFIID, TAFII80
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). Interacts with Tbp and Taf4.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Taf5 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Taf5 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Taf80 CG7704
dsRNA has been made from templates generated with primers directed against this gene.
Does not interact, in vitro, with human thryroid-hormone receptor-β.
TFIID subunit proteins and the Tbp protein can interact in pairwise combinations with several subunits in a network of interactions within TFIID.
Purified TAF80 is unable to bind TBP directly or to interact strongly with the C-terminal domain of TAF250, but can only interact with a complex containing TBP, TAF250, TAF110 and TAF60.
A number of polypeptides (encoded by Taf1, Taf4, Taf5, Taf6, e(y)1 and Taf12) that are tightly associated with Tbp and are native TFIID components have been purified. Protein blotting experiments suggest that one of these proteins, Taf1, interacts directly with Tbp, while the association between Tbp and the other proteins is either weak or is an indirect association via Taf1.