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Gene Dmel\Bap

General Information
Symbol	Dmel\Bap	Species	D. melanogaster
Name	Β Adaptin	Annotation symbol	CG12532
Feature type	protein_coding_gene	FlyBase ID	FBgn0010380
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	AP-2β, BAD1
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	18E4-18E5	Sequence location	X:19,625,036..19,628,620 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Β Adaptin is referred to in FlyBase by the symbol Dmel\Bap (CG12532, FBgn0010380). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding; protein transporter activity. It is reported to be involved in the biological process: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Adaptor protein complex, beta subunit; Armadillo-like helical; Armadillo-type fold; Beta2-adaptin/TATA-box binding, C-terminal; Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain; Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Coatomer/calthrin adaptor appendage, C-terminal subdomain; Coatomer/clathrin adaptor appendage, Ig-like subdomain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult midgut, adult fat body, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638673_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Bap. Gene sequence location is X:19625036..19628620.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms AP-type membrane coat adaptor complex
FB2012_01	References Yang et al., 2011, Neuron 72(2): 285--299 Sequence features HFA19336 BKN27495
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 18E4-18E5   Limits computationally determined from genome sequence between P{EP}Sec61γEP1511 and P{EP}EP1116&P{EP}EP1344EP1344
Experimentally Determined Cytological Location
Cytogenetic map Notes References 18E1-18E2     (Pearse, 1993.11.2) 18E-18F   Determined by comparing Celera genomic sequence with sequence from BDGP BAC and P1 clones.   (Lloyd et al., 2000)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Bap for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone appears problematic: incomplete CDS (SD04106)
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Bap-RA FBtr0074789  NM_078691   3235   921
Additional Transcript Data & Comments
Reported size (kB)	3.217 (longest cDNA) (Camidge and Pearse, 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Bap-PA   FBpp0074558   101.2   921   4.73     NP_523415   AAF49013
Additional Polypeptide Data & Comments
Reported size (kDa)	921 (aa); 100 (kD observed) (Camidge and Pearse, 1994)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Clathrin/coatomer adaptor, adaptin-like, N-terminal (IPR002553) Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (IPR008152) Coatomer/calthrin adaptor appendage, C-terminal subdomain (IPR009028) Armadillo-like helical (IPR011989) Beta2-adaptin/TATA-box binding, C-terminal (IPR012295) Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain (IPR013037) Coatomer/clathrin adaptor appendage, Ig-like subdomain (IPR013041) Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain (IPR015151) Armadillo-type fold (IPR016024) Adaptor protein complex, beta subunit (IPR016342)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142180   AA201182   AA392346   AA816469   AA820488   AA941421   AA942336   AA949541   AE014298 AAF49013   AI063307   AI063523   AI107334   AI107565   AI135091   AI135562   AI239245   AI295119   AI386601   AI387259   AI387697   AI388073   AI388197   AI388686   AI403306   AI404669   AI455689   AI456969   AI512712   AI519460   AI530805   AI532560   AI533827   AI534415   AI534518   AI534994   AW944345   AY052092 AAK93516   BF486291   BF486886   BF494401   BG635233   BG639491   BG640184   BI164240   BI164340   BI164423   BI168170   BI170153   BI170960   BI213307   BI213509   BI215361   BI236447   BI237021   BI240237   BI240330   BI357920   BI358384   BI361690   BI365693   BI483538   BI566870   BI568424   BI574981   BI575513   BI578519   BI579703   BI580646   BI582656   BI587006   BI588143   BI589342   BI616242   BI626712   BI634972   BP544948   BP544949   BT016054 AAV36939   BX070545   CK132016   CK604718   CK657613   CK659076   CK659980   CO279518   CO296871   CO333070   EC051736   EC067906   EC212014   EC227113   EC232780   EC247714   EV580753   EV595386   GH740612   GH741334   GH744843   GH762880   GH763037   GH763225   GH763518   GH764452   GH766338   GH766694   GH767141   GH767164   X75910 CAA53509
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q24253 Q960F2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
	Immunolocalization studies with Drosophila Kc cells reveal a punctate pattern of Bap protein distribution, possibly in coated pits. (Camidge and Pearse, 1994)
Marker for
Subcellular Localization
CV Term	coated pit (Camidge and Pearse, 1994)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0010380    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0010380 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0010380 expression level Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7743) embryo 02-04hr  (6535) embryo 04-06hr  (5066) embryo 06-08hr  (6050) embryo 08-10hr  (5813) embryo 10-12hr  (6355) embryo 12-14hr  (4272) embryo 14-16hr  (5845) embryo 16-18hr  (4263) embryo 18-20hr  (3881) embryo 20-22hr  (3189) embryo 22-24hr  (2983) larva L1  (4033) larva L2  (3500) larva L3 12hr old  (2546) larva L3 puffstage 1-2  (2518) larva L3 puffstage 3-6  (3667) larva L3 puffstage 7-9  (4101) white prepupae new  (4735) white prepupae 12hr  (3961) white prepupae 24hr  (4348) pupae 2d postWPP  (4063) pupae 3d postWPP  (2920) pupae 4d postWPP  (2727) adult male 01day  (2946) adult male 05day  (2965) adult male 30day  (3126) adult female 01day  (5114) adult female 05day  (5010) adult female 30day  (5263) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7743) embryo 02-04hr  (6535) embryo 04-06hr  (5066) embryo 06-08hr  (6050) embryo 08-10hr  (5813) embryo 10-12hr  (6355) embryo 12-14hr  (4272) embryo 14-16hr  (5845) embryo 16-18hr  (4263) embryo 18-20hr  (3881) embryo 20-22hr  (3189) embryo 22-24hr  (2983) larva L1  (4033) larva L2  (3500) larva L3 12hr old  (2546) larva L3 puffstage 1-2  (2518) larva L3 puffstage 3-6  (3667) larva L3 puffstage 7-9  (4101) white prepupae new  (4735) white prepupae 12hr  (3961) white prepupae 24hr  (4348) pupae 2d postWPP  (4063) pupae 3d postWPP  (2920) pupae 4d postWPP  (2727) adult male 01day  (2946) adult male 05day  (2965) adult male 30day  (3126) adult female 01day  (5114) adult female 05day  (5010) adult female 30day  (5263) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0010380 expression level Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7743) embryo 02-04hr  (6535) embryo 04-06hr  (5066) embryo 06-08hr  (6050) embryo 08-10hr  (5813) embryo 10-12hr  (6355) embryo 12-14hr  (4272) embryo 14-16hr  (5845) embryo 16-18hr  (4263) embryo 18-20hr  (3881) embryo 20-22hr  (3189) embryo 22-24hr  (2983) larva L1  (4033) larva L2  (3500) larva L3 12hr old  (2546) larva L3 puffstage 1-2  (2518) larva L3 puffstage 3-6  (3667) larva L3 puffstage 7-9  (4101) white prepupae new  (4735) white prepupae 12hr  (3961) white prepupae 24hr  (4348) pupae 2d postWPP  (4063) pupae 3d postWPP  (2920) pupae 4d postWPP  (2727) adult male 01day  (2946) adult male 05day  (2965) adult male 30day  (3126) adult female 01day  (5114) adult female 05day  (5010) adult female 30day  (5263) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7743) embryo 02-04hr  (6535) embryo 04-06hr  (5066) embryo 06-08hr  (6050) embryo 08-10hr  (5813) embryo 10-12hr  (6355) embryo 12-14hr  (4272) embryo 14-16hr  (5845) embryo 16-18hr  (4263) embryo 18-20hr  (3881) embryo 20-22hr  (3189) embryo 22-24hr  (2983) larva L1  (4033) larva L2  (3500) larva L3 12hr old  (2546) larva L3 puffstage 1-2  (2518) larva L3 puffstage 3-6  (3667) larva L3 puffstage 7-9  (4101) white prepupae new  (4735) white prepupae 12hr  (3961) white prepupae 24hr  (4348) pupae 2d postWPP  (4063) pupae 3d postWPP  (2920) pupae 4d postWPP  (2727) adult male 01day  (2946) adult male 05day  (2965) adult male 30day  (3126) adult female 01day  (5114) adult female 05day  (5010) adult female 30day  (5263) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7743 embryo 02-04hr    6535 embryo 04-06hr    5066 embryo 06-08hr    6050 embryo 08-10hr    5813 embryo 10-12hr    6355 embryo 12-14hr    4272 embryo 14-16hr    5845 embryo 16-18hr    4263 embryo 18-20hr    3881 embryo 20-22hr    3189 embryo 22-24hr    2983 larva L1    4033 larva L2    3500 larva L3 12hr old    2546 larva L3 puffstage 1-2    2518 larva L3 puffstage 3-6    3667 larva L3 puffstage 7-9    4101 white prepupae new    4735 white prepupae 12hr    3961 white prepupae 24hr    4348 pupae 2d postWPP    4063 pupae 3d postWPP    2920 pupae 4d postWPP    2727 adult male 01day    2946 adult male 05day    2965 adult male 30day    3126 adult female 01day    5114 adult female 05day    5010 adult female 30day    5263 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0010380    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0010380 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, adult midgut, adult fat body, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0010380 expression level Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland    1298.6 Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion    1168.5 Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland    1090.6 Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (867.375) Larval Midgut  (729.7) Larval Hindgut  (953.5) Larval Malpighian Tubules  (953.7) Larval Fat Body  (631.4) Larval Salivary Gland  (1298.6) Larval Trachea  (650.1) Larval Carcass  (581.8) Adult Head  (555.1) Adult Eye  518.775 Adult Brain  (923.2) Adult Thoracic-Abdominal Ganglion  (1168.5) Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut  (539.9) Adult Malpighian Tubules  532.5 Adult Fat Body    425.8 Adult Salivary Gland  (976.7) Adult Heart  (810.125) Adult VirginFemale Spermatheca  (683.5) Adult InseminatedFemale Spermatheca  (820.7) Adult Ovary  (604.5) Adult Testis    160.7 Adult Male Accessory Gland  (1090.6) Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland  (1298.6) Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion  (1168.5) Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland  (1090.6) Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland    1298.6 Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion    1168.5 Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland    1090.6 Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0010380 expression level Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland    1298.6 Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion    1168.5 Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland    1090.6 Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (867.375) Larval Midgut  729.7 Larval Hindgut  (953.5) Larval Malpighian Tubules  (953.7) Larval Fat Body  631.4 Larval Salivary Gland  (1298.6) Larval Trachea  650.1 Larval Carcass  581.8 Adult Head  555.1 Adult Eye  518.775 Adult Brain  (923.2) Adult Thoracic-Abdominal Ganglion  (1168.5) Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut  539.9 Adult Malpighian Tubules  532.5 Adult Fat Body    425.8 Adult Salivary Gland  (976.7) Adult Heart  810.125 Adult VirginFemale Spermatheca  683.5 Adult InseminatedFemale Spermatheca  (820.7) Adult Ovary  604.5 Adult Testis    160.7 Adult Male Accessory Gland  (1090.6) Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland  1298.6 Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion  1168.5 Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland  1090.6 Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    867.375 Larval Midgut    729.7 Larval Hindgut    953.5 Larval Malpighian Tubules    953.7 Larval Fat Body    631.4 Larval Salivary Gland    1298.6 Larval Trachea    650.1 Larval Carcass    581.8 Adult Head    555.1 Adult Eye    518.775 Adult Brain    923.2 Adult Thoracic-Abdominal Ganglion    1168.5 Adult Crop    463.3 Adult Midgut    462.1 Adult Hindgut    539.9 Adult Malpighian Tubules    532.5 Adult Fat Body    425.8 Adult Salivary Gland    976.7 Adult Heart    810.125 Adult VirginFemale Spermatheca    683.5 Adult InseminatedFemale Spermatheca    820.7 Adult Ovary    604.5 Adult Testis    160.7 Adult Male Accessory Gland    1090.6 Adult Carcass    436 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    555.1   NA  Eye    518.775   NA  Brain    923.2   867.375  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1168.5   NA  Crop    463.3   729.7  Midgut    462.1   953.5  Hindgut    539.9   953.7  Malpighian Tubules    532.5   631.4  Fat Body    425.8   1298.6  Salivary Gland    976.7   NA  Heart    810.125   650.1  Trachea    NA   NA  VirginFemale Spermatheca    683.5   NA  InseminatedFemale Spermatheca    820.7   NA  Ovary    604.5   NA  Testis    160.7   NA  Male Accessory Gland    1090.6   581.8  Carcass    436 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010380 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12532-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 BapGD1204 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Bap Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Bap Class Mutagen Stocks Known lesion BapGD1204 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes BapHM04014 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes BapJF02963 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes BapdsRNA.cRa in vitro construct - RNAi 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6253 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1204} NA P{TRiP.HM04014} NA P{TRiP.JF02963} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
AP-type membrane coat adaptor complex inferred from direct assay (Camidge and Pearse, 1994) coated pit inferred from direct assay (Camidge and Pearse, 1994)
Terms Based on Predictions or Assertions ( 10 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR012295, InterPro:IPR016024 (FlyBase Curators et al., 2004-) protein transporter activity inferred from electronic annotation with InterPro:IPR016342 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
intracellular protein transport inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR009028, InterPro:IPR013037, InterPro:IPR015151 (FlyBase Curators et al., 2004-) neurotransmitter secretion non-traceable author statement (Stimson and Ramaswami, 1999) synaptic vesicle coating traceable author statement (Stimson and Ramaswami, 1999) vesicle coating traceable author statement (Stimson and Ramaswami, 1999) vesicle-mediated transport inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR009028, InterPro:IPR013037, InterPro:IPR015151 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
AP-1 adaptor complex inferred from sequence or structural similarity with human AP1B1 (FlyBase, 1992-) non-traceable author statement (Pearse, 1993.11.2) coated vesicle traceable author statement (Stimson and Ramaswami, 1999) synaptic vesicle traceable author statement (Stimson and Ramaswami, 1999)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Bap allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59282 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010380 DroID - A comprehensive database of gene and protein interactions. • FBgn0010380 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32987
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20213 Dere\GG19251 Dgri\GH17690 Dmoj\GI16098 Dper\GL15014 Dpse\GA11682 Dsim\GD17460 Dvir\GJ15746 Dwil\GK17345 Dyak\GE15870
Curated drosophilid orthologs	Dpse\GA11682   Dsim\Bap (Nurminsky et al., 2001)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL011650-PA Aedes aegypti (mosquito) XP_001945401.1 Acyrthosiphon pisum (pea aphid) At4g11380.1 Arabidopsis thaliana (wall cress) 87982 Batrachochytrium dendrobatidis (chytrid fungus) 126313 Branchiostoma floridae (lancelet) 257887 Branchiostoma floridae (lancelet) XP_001897209.1 Brugia malayi (roundworm nematode) BGIBMGA012922-PA Bombyx mori (silk worm) ENSBTAP00000001576 Bos taurus (bovine) CAL0003949 Candida albicans (a form of yeast) CN27248 Caenorhabditis brenneri (small nematode) CBP02477 Caenorhabditis briggsae (nematode) CE29919 Caenorhabditis elegans (worm) ENSCAFP00000017800 Canis familiaris (dog) CAGL0D02068g Candida glabrata (haploid yeast) Chro.60567 Cryptosporidium hominis (obligate parasite) CMR021C Cyanidioschyzon merolae (red alga) cn09295 Cryptococcus neoformans (yeast-like fungus) cgd4_4300 Cryptosporidium parvum (protozoan parasite) CPIJ001176 Culex pipens (mosquito) ENSCPOP00000004761 Cavia porcellus (guinea pig) 179040 Chlamidomonas reinhardtii (green alga) RP46836 Caenorhabditis remanei (nematode) ENSCSAVP00000016408 Ciona savignyi (sedentary tunicate) 149233 Capitella spl (polychaete worm) DDB0234067 Dictyostelium discoideum (amoeba) DEHA2F17622g Debaryomyces Hansenii (yeast) 324067 Daphnia pulex (daphnia) ENSDARP00000089713 Danio rerio (zebra fish) ENSECAP00000017229 Equus caballus (horse) XP_649291 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000027448 Gymnopilus aculeatus (mushroom) ENSGALP00000003342 Gallus gallus (chicken) GL50803_21423 Giardia lamblia (flagellated protozoan) 193557 Hypsipyla robusta (cedar shoot borer) ENSP00000350199 Homo sapiens (human) ISCW011108-PA Ixodes scapularis (deer tick) KLLA0E12255g Kluyveromyces lactis (yeast) 198868 Lottia gigantea (owl limpet) LmjF36.6770 Leishmania major (virus) 12202 Monocosta brevicollis (choanoflagellate) ENSMODP00000011033 Monodelphis domestica (gray opossum) ENSMMUP00000028164 Macaca mulatta (rhesus monkey) ENSMUSP00000070598 Mus musculus (house mouse) 190491 Nematostella vectensis (starlet anemone) XP_001607195.1 Nasonia vitripennis (wasp) ENSOANP00000027348 Ornithorynchus anatinus (platypus) ENSORLP00000018149 Oryzias latipes (japanese killifish) LOC_Os03g23950.1 Oryza sativa (asian rice) 16632 Ostreococcus tauri (green alga) PFE1400c Plasmodium falciparum (protozoal parasite) PHUM001377-PA Pediculus humanus (human body louse) PP21425 Pristionchus pacificus (nematode) 225918 Physcomitrella patens (moss) ENSPPYP00000013038 Pongo pygmaeus (orangutan) 71968 Phytophthora ramorum (sudden oak death pathogen) 109501 Phytophthora sojae (root rot pathogen) 709305 Populus trichocarpa (black cottonwood) 757540 Populus trichocarpa (black cottonwood) ENSPTRP00000042158 Pan troglodytes (chimpanzee) PVX_079845 Plasmodium vivax (protozoal parasite) ENSRNOP00000011822 Rattus norvegicus (norway rat) 4866442 Sorghum bicolor (sorghum) YKL135C Saccharomyces cerevisiae (budding yeast) Smp_034870 Schistosoma mansoni (trematode parasite) SPBC947.02 Schizosaccharomyces pombe (fission yeast) XP_001187613.1 Strongylocentrotus purpuratus (purple sea urchin) XP_802010.2 Strongylocentrotus purpuratus (purple sea urchin) 57237 Trichoplax adhaerens (metazoa) TA12430 Theileria annulata (apicomplexan parasite) XP_001812413.1 Tribolium castaneum (red flour beetle) Tc00.1047053506247.200 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000010460 Tetraodon nigroviridis (green spotted pufferfish) TP02_0304 Theileria parva (parasitic protozoan) 41687 Thalassiosira pseudonana (marine diatom) ENSTRUP00000017377 Takifugu rubripes (pufferfish Takifugu) 3829.m01154 Tetrahymena thermophila (ciliate protozoa) 81529.m00500 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000035832 Xenopus tropicalis (frog) YALI0F21769g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11994 LH13961 ISCW011108 FBgn0233431 FBgn0219344 FBgn0202934 FBgn0177856 FBgn0177855 JGI_V11_337718 JGI_V11_324067 FBgn0071732 FBgn0152618 FBgn0138847 FBgn0125160 FBgn0111456 FBgn0097220 CPIJ001176 BGIBMGA012922 ACYPI008606 GB16141 AGAP001267 AAEL011650 PB26037 PHUM255010 GLEAN_15061
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	28328 y1 v1; P{TRiP.JF02963}attP2 31707 y1 v1; P{TRiP.HM04014}attP2
VDRC	v7720 w1118; P{GD1204}v7720/TM3 v7721 w1118; P{GD1204}v7721/TM3
Genomic Clones ( 2 )
	BACR33M08 BACR48P17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 102 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP17054 SD04106
Other clones	DPiM_LP17054
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02878 AT20552 AT21431 AT31751 GH03043 GH03387 GH04140 GH05311 GH12721 GH13367 GH16735 GH17739 GH18291 GH18829 GH19016 GH19661 GH22718 GH24463 HL03706 LD01870 LD04106 LD11191 LD24238 LD25553 LD26481 LD28376 LD35332 LD37153 LD39066 LD44675 LP08657 LP13177 LP16543 LP18164 LP24054 RE03871 RE04002 RE04091 RE08741 RE11520 RE12596 RE18681 RE18925 RE21742 RE32505 RE33165 RE36937 RE37154 RE44548 RE45128 RE46020 RE46416 RE66449 RE72395 RE73774 RE74863 RH20938 RH27255 RH27537 RH29230 RH31209 RH31763 RH36645 RH39868 RH39958 RH46139 RH67734 SD01315 SD05792 SD07226 SD07405 SD11148 UT01402
Other clones	21342 64244 82042 165583 280972 CK00332 Dmel_dig_005075_0707_1944 Dmel_neb_013396_0640_2536 EC051736 EK134947 EK215331 EK305619 FGC028F09 RP001014085 RP001018285 RP001020883 RP001021988 RP001022713 RP001033756 RP001034084 RP001034267 RP001037041 RP001045070 RP001049646 RP001053504 SD01528
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010380 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32987
Antibody Information
	polyclonal (Camidge and Pearse, 1994)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. (Claridge-Chang et al., 2001) Isolated from a Drosophila embryonic cDNA library, using a fragment encoding bases 976 to 1938 of human β-adaptin as a probe. (Camidge and Pearse, 1994) A Bap cDNA has been cloned and sequenced. (Camidge and Pearse, 1994)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078691 RefSeq (Proteins) • NP_523415 DDBJ / EMBL / GenBank • AAF49013 AAK93516 AAV36939 AI532560 AW944345 AY052092 BT016054 CAA53509 X75910 Entrez Gene - A searchable database of RefSeq genes. • 32987 UniProtKB/TrEMBL • Q960F2 Q24253
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Clathrin/coatomer adaptor, adaptin-like, N-terminal (IPR002553) Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (IPR008152) Coatomer/calthrin adaptor appendage, C-terminal subdomain (IPR009028) Armadillo-like helical (IPR011989) Beta2-adaptin/TATA-box binding, C-terminal (IPR012295) Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain (IPR013037) Coatomer/clathrin adaptor appendage, Ig-like subdomain (IPR013041) Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain (IPR015151) Armadillo-type fold (IPR016024) Adaptor protein complex, beta subunit (IPR016342)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59282 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010380 DroID - A comprehensive database of gene and protein interactions. • FBgn0010380 DRSC - Results from RNAi screens. • FBgn0010380 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010380 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12532-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010380 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32987 InParanoid A subset of ortholog calls from InParanoid. • AAEL011650-PA Aedes aegypti (mosquito) XP_001945401.1 Acyrthosiphon pisum (pea aphid) At4g11380.1 Arabidopsis thaliana (wall cress) 87982 Batrachochytrium dendrobatidis (chytrid fungus) 126313 Branchiostoma floridae (lancelet) 257887 Branchiostoma floridae (lancelet) XP_001897209.1 Brugia malayi (roundworm nematode) BGIBMGA012922-PA Bombyx mori (silk worm) ENSBTAP00000001576 Bos taurus (bovine) CAL0003949 Candida albicans (a form of yeast) CN27248 Caenorhabditis brenneri (small nematode) CBP02477 Caenorhabditis briggsae (nematode) CE29919 Caenorhabditis elegans (worm) ENSCAFP00000017800 Canis familiaris (dog) CAGL0D02068g Candida glabrata (haploid yeast) Chro.60567 Cryptosporidium hominis (obligate parasite) CMR021C Cyanidioschyzon merolae (red alga) cn09295 Cryptococcus neoformans (yeast-like fungus) cgd4_4300 Cryptosporidium parvum (protozoan parasite) CPIJ001176 Culex pipens (mosquito) ENSCPOP00000004761 Cavia porcellus (guinea pig) 179040 Chlamidomonas reinhardtii (green alga) RP46836 Caenorhabditis remanei (nematode) ENSCSAVP00000016408 Ciona savignyi (sedentary tunicate) 149233 Capitella spl (polychaete worm) DDB0234067 Dictyostelium discoideum (amoeba) DEHA2F17622g Debaryomyces Hansenii (yeast) 324067 Daphnia pulex (daphnia) ENSDARP00000089713 Danio rerio (zebra fish) ENSECAP00000017229 Equus caballus (horse) XP_649291 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000027448 Gymnopilus aculeatus (mushroom) ENSGALP00000003342 Gallus gallus (chicken) GL50803_21423 Giardia lamblia (flagellated protozoan) 193557 Hypsipyla robusta (cedar shoot borer) ENSP00000350199 Homo sapiens (human) ISCW011108-PA Ixodes scapularis (deer tick) KLLA0E12255g Kluyveromyces lactis (yeast) 198868 Lottia gigantea (owl limpet) LmjF36.6770 Leishmania major (virus) 12202 Monocosta brevicollis (choanoflagellate) ENSMODP00000011033 Monodelphis domestica (gray opossum) ENSMMUP00000028164 Macaca mulatta (rhesus monkey) ENSMUSP00000070598 Mus musculus (house mouse) 190491 Nematostella vectensis (starlet anemone) XP_001607195.1 Nasonia vitripennis (wasp) ENSOANP00000027348 Ornithorynchus anatinus (platypus) ENSORLP00000018149 Oryzias latipes (japanese killifish) LOC_Os03g23950.1 Oryza sativa (asian rice) 16632 Ostreococcus tauri (green alga) PFE1400c Plasmodium falciparum (protozoal parasite) PHUM001377-PA Pediculus humanus (human body louse) PP21425 Pristionchus pacificus (nematode) 225918 Physcomitrella patens (moss) ENSPPYP00000013038 Pongo pygmaeus (orangutan) 71968 Phytophthora ramorum (sudden oak death pathogen) 109501 Phytophthora sojae (root rot pathogen) 709305 Populus trichocarpa (black cottonwood) 757540 Populus trichocarpa (black cottonwood) ENSPTRP00000042158 Pan troglodytes (chimpanzee) PVX_079845 Plasmodium vivax (protozoal parasite) ENSRNOP00000011822 Rattus norvegicus (norway rat) 4866442 Sorghum bicolor (sorghum) YKL135C Saccharomyces cerevisiae (budding yeast) Smp_034870 Schistosoma mansoni (trematode parasite) SPBC947.02 Schizosaccharomyces pombe (fission yeast) XP_001187613.1 Strongylocentrotus purpuratus (purple sea urchin) XP_802010.2 Strongylocentrotus purpuratus (purple sea urchin) 57237 Trichoplax adhaerens (metazoa) TA12430 Theileria annulata (apicomplexan parasite) XP_001812413.1 Tribolium castaneum (red flour beetle) Tc00.1047053506247.200 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000010460 Tetraodon nigroviridis (green spotted pufferfish) TP02_0304 Theileria parva (parasitic protozoan) 41687 Thalassiosira pseudonana (marine diatom) ENSTRUP00000017377 Takifugu rubripes (pufferfish Takifugu) 3829.m01154 Tetrahymena thermophila (ciliate protozoa) 81529.m00500 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000035832 Xenopus tropicalis (frog) YALI0F21769g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32987 modMine - Data generated by the modENCODE project. • FBgn0010380 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV11994 LH13961 ISCW011108 FBgn0233431 FBgn0219344 FBgn0202934 FBgn0177856 FBgn0177855 JGI_V11_337718 JGI_V11_324067 FBgn0071732 FBgn0152618 FBgn0138847 FBgn0125160 FBgn0111456 FBgn0097220 CPIJ001176 BGIBMGA012922 ACYPI008606 GB16141 AGAP001267 AAEL011650 PB26037 PHUM255010 GLEAN_15061
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	AP-2β (Lloyd et al., 2000, Orem et al., 2006) AP-β1 (Ramet et al., 2002) BAD1 (Pearse, 1993.11.2, Camidge and Pearse, 1994) bap (Bellen, 2000.12.25) Bap (Yang et al., 2011) CG12532 (Ramet et al., 2002, Boehm, 2001, Verstreken and Bellen, 2000.9.4, Legube et al., 2006, Perkins et al., 2009, Ni et al., 2008, Cammarato et al., 2011) cg12532 (Boehm and Bonifacino, 2002) β1/2 (Boehm and Bonifacino, 2001)
Name Synonym	Beta Adaptin (Cammarato et al., 2011) Beta Adaptin Drosophila 1 (Camidge and Pearse, 1994) Β Adaptin   β-adaptin (Lewin and Mellman, 1998, Newman et al., 1995, Yang et al., 2011)
Secondary FlyBase IDs
References ( 37 )
Generate a list of	All references relating to this gene ( 37 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 8 ) Review  ( 6 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 1 )
	Yang et al., 2011, Neuron 72(2): 285--299 Nak regulates localization of clathrin sites in higher-order dendrites to promote local dendrite growth. [FBrf0216477] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...