Dbi, ACBP, Diazepam-binding inhibitor
Please see the JBrowse view of Dmel\Acbp2 for information on other features
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Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Acbp2 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Acbp2 in GBrowse 23-19
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Acbp2 Dbi
Source for merge of: Dbi BcDNA:RH39533
Source for merge of: Dbi anon-WO0172774.131
FlyBase curator comment: Renamed from 'Dbi' because: (i) there's no evidence that the fly gene product is a "Diazepam-binding inhibitor"; (ii) one of the original authors that characterized the D. melanogaster gene (see FBrf0076972) later said that "the binding of Acyl-CoA is the only function of DBI/ACBP which has been supported with remarkable body of experimental evidence...it is highly unlikely that the real function of ACBP/DBI would be binding of diazepam" (FBrf0129015); and (iii) it makes sense to name this gene using the "Acbp" prefix as part of the "Acyl-CoA binding protein 1" family identified in the this paper.
Source for merge of Dbi BcDNA:RH39533 was a shared cDNA ( date:030728 ).
Source for merge of Dbi anon-WO0172774.131 was sequence comparison ( date:051113 ).
Isolated from a genomic library using a rat DBI cDNA as a probe, under low stringency conditions.
Dbi has been cloned and sequenced, and its expression pattern has been analysed.