FlyBase Gene Report: Dmel\Gtp-bp

Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). May have a role in axonogenesis.

(UniProt, Q9U5L1)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\Gtp-bp or the JBrowse view of Dmel\Gtp-bp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Gtp-bp-RA

FBtr0073480

NM_080148

2056

614

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Gtp-bp-PA

FBpp0073336

67.8

614

6.80

NP_524887

AAF48002

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Heterodimer of an alpha and a beta chain.

(UniProt, Q9U5L1)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

UniProt

Q9U5L1

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gtp-bp using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Gtp-bp_1

Linkouts

Gene Ontology (13 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

GTP binding

inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR007222, InterPro:IPR013822

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

GTPase activity

inferred from biological aspect of ancestor with PANTHER:PTN000169915

(assigned by GO_Central )

(Gaudet et al., 2011)

RNA binding

non-traceable author statement

(assigned by UniProt )

(Fredieu and Mahowald, 1993)

signal recognition particle binding

inferred from biological aspect of ancestor with PANTHER:PTN000169915

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (5 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

axonogenesis

inferred from expression pattern

(assigned by UniProt )

(Fredieu and Mahowald, 1993)

regulation of protein secretion

inferred from expression pattern

(assigned by UniProt )

(Fredieu and Mahowald, 1993)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

protein targeting

inferred from biological aspect of ancestor with PANTHER:PTN000169915

(assigned by GO_Central )

(Gaudet et al., 2011)

protein targeting to ER

inferred from biological aspect of ancestor with PANTHER:PTN000169918

(assigned by GO_Central )

(Gaudet et al., 2011)

SRP-dependent cotranslational protein targeting to membrane

inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR013822

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

endoplasmic reticulum membrane

inferred from direct assay

(assigned by UniProt )

(Fredieu and Mahowald, 1993)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

endoplasmic reticulum membrane

inferred from biological aspect of ancestor with PANTHER:PTN000169918

(assigned by GO_Central )

(Gaudet et al., 2011)

membrane

inferred from biological aspect of ancestor with PANTHER:PTN000169915

(assigned by GO_Central )

(Gaudet et al., 2011)

signal recognition particle receptor complex

inferred from electronic annotation with InterPro:IPR007222

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 10 -- 11

embryonic/larval trachea

(Chung et al., 2011)

embryonic stage 11

salivary gland body primordium

(Abrams and Andrew, 2005)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

hindgut proper primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

salivary gland body primordium

(Fisher et al., 2012)

salivary gland duct primordium

(Fisher et al., 2012)

tracheal primordium

(Fisher et al., 2012)

embryonic stage 11 -- 15

salivary gland body primordium

(Fox et al., 2010)

embryonic stage 11 -- 16

embryonic epidermis

(Fox et al., 2010)

embryonic stage 12

ventral midline | dorsal | segmentally repeated

(Fredieu and Mahowald, 1993)

embryonic stage 13 -- 14

presumptive embryonic salivary gland

(Abrams and Andrew, 2005)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

embryonic/larval salivary gland

(Fisher et al., 2012)

embryonic/larval salivary gland body

(Fisher et al., 2012)

embryonic stage 15

proventriculus primordium

(Fox et al., 2010)

embryonic stage 16

embryonic proventriculus

(Fox et al., 2010)

embryonic/larval salivary gland

(Fox et al., 2010)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 17

organism

(Fredieu and Mahowald, 1993)

Additional Descriptive Data

Gtp-bp transcripts are expressed at high levels throughout embryogenesis with a peak between 12 and 18 hrs. They are found lateral to the dorsal-most regions of the ventral midline and show a segmentally repeating pattern.

(Fredieu and Mahowald, 1993)

Marker for

salivary gland body primordium

(Abrams and Andrew, 2005)

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

ventral midline

(Fredieu and Mahowald, 1993)

embryonic/larval digestive system

(Fredieu and Mahowald, 1993)

stomodeum

(Fredieu and Mahowald, 1993)

embryonic stage 13 -- 17

presumptive embryonic/larval central nervous system

(Fredieu and Mahowald, 1993)

embryonic stage 16 -- 17

intersegmental nerve

(Fredieu and Mahowald, 1993)

peripheral nervous system

(Fredieu and Mahowald, 1993)

segmental nerve

(Fredieu and Mahowald, 1993)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

western blot

Stage

Tissue/Position (including subcellular localization)

Reference

neuroblast

Comment: cultured neuroblasts

(Fredieu and Mahowald, 1993)

Additional Descriptive Data

In germ band extended embryos, Gtp-bp protein is detected in cells dorsal to the ectoderm and is distributed in a continuous layer from the stomodeal opening to the end of the germ band. It is also found at the anterior tip of the clypeolabrum and in the posterior gut. During germ band retraction, it becomes confined within the ventral midline, dorsal to the delaminating neuroblasts. The midline cells expressing Gtp-bp protein send a broad process across the midline just ventral to the yolk sac to the contralateral neuromere. At this stage, a single cell in each neuromere is detected. Later, protein is detected on axons that cross the midline and in other cells and processes in lateral regions of each neuromere. Starting in stage 13, Gtp-bp protein is detected in ventral, lateral and dorsal sensilla of the PNS. In later embryos, protein is detected in the intersegmental nerve and the segmental nerve on axons and on subsets of PNS cell soma.

(Fredieu and Mahowald, 1993)

Marker for

Subcellular Localization

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

endoplasmic reticulum membrane

inferred from direct assay

(assigned by UniProt )

(Fredieu and Mahowald, 1993)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Gtp-bp in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Gtp-bp

View exonic expression by tissue for Dmel\Gtp-bp

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010391

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0010391

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2522-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2522

Flygut - An atlas of the Drosophila adult midgut

FBgn0010391

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Gtp-bp

Stages(s) 4-6
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Gtp-bp

Transgenic constructs containing regulatory region of Gtp-bp

Deletions and Duplications ( 0 )

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Mef2.PR

Gtp-bp^GD6482

lethal, with Scer\GAL4^pnr-MD237

Gtp-bp^GD6482

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Gtp-bp^GD6482

viable, with Scer\GAL4^tin.CΔ4

Gtp-bp^GD6482

Other Phenotypes

Allele

pain response defective | adult stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Gtp-bp^GD6482

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\SRPRA

14 of 15

Yes

Hsap\HIST2H3D

1 of 15

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Srpr

13 of 15

Yes

Rattus norvegicus (Norway rat) (1)

Rnor\Srpra

13 of 13

Yes

Xenopus tropicalis (Western clawed frog) (1)

Xtro\srpra

8 of 12

Yes

Danio rerio (Zebrafish) (1)

Drer\srpr

14 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\F38A1.8

12 of 15

Yes

Arabidopsis thaliana (thale-cress) (2)

Atha\AT4G30600

8 of 9

Yes

Atha\CPFTSY

1 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\SRP101

12 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPBC3B9.03

12 of 12

Yes

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091905MG )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\Gtp-bp

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15385

Drosophila persimilis

Dper\GL27063

Drosophila willistoni

Dwil\GK16226

Drosophila virilis

Dvir\GJ16008

Drosophila mojavensis

Dmoj\GI21534

Drosophila grimshawi

Dgri\GH24806

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503OG )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17017572

Glossina morsitans

Tsetse fly

Gmor\GMOY002768

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01529

Mayetiola destructor

Hessian fly

Mdes\Mdes006617

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005856

Anopheles darlingi

American malaria mosquito

Adar\ADAC004745

Anopheles gambiae

Malaria mosquito

Agam\AGAP010894

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ005421

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03RU )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA008392

Danaus plexippus

Monarch butterfly

Dple\DPOGS205452-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL017742

Heliconius melpomene

Postman butterfly

Hmel\HMEL011797

Apis florea

Little honeybee

Aflo\2241034372

Apis mellifera

Western honey bee

Amel\Gtp-bp

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP15838

Bombus terrestris

Buff-tailed bumblebee

Bter\15210601

Linepithema humile

Argentine ant

Lhum\LH13160

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0003fa

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG020757

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_00368

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_00341

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_01145

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_07993

Pediculus humanus

Human body louse

Phum\PHUM229330

Rhodnius prolixus

Kissing bug

Rpro\RPRC000348

Cimex lectularius

Bed bug

Clec\CLEC012913

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI009644

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_04351

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03P0 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR005909

Ixodes scapularis

Black-legged tick

Isca\ISCW007119

Ixodes scapularis

Black-legged tick

Isca\ISCW015342

Stegodyphus mimosarum

African social velvet spider

Smim\KFM82908.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur08g01610

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_300824

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G05TG )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Sra

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000008954

Gallus gallus

Domestic chicken

Ggal\SRPR

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (0)

No records found.

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SRPRA; SRP receptor subunit alpha

14 of 15

182180

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Gtp-bp - S6kII

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

Gtp-bp - SrpRβ

experimental knowledge based

(Guruharsha et al., 2011)

Gtp-bp - gig

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

Gtp-bp - rictor

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

Heterodimer of an alpha and a beta chain.

(UniProt, Q9U5L1 )

Linkouts

BioGRID - A database of protein and genetic interactions.

70718

DroID - A comprehensive database of gene and protein interactions.

FBgn0010391

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

47251

MIST (protein-protein) - An integrated Molecular Interaction Database

Gtp-bp

Pathways

Gene Group - Pathway Membership (FlyBase)

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-33

Cytogenetic map

10A6-10A6

Sequence location

X:11,126,877..11,129,087 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

10A6-10A6

Limits computationally determined from genome sequence between P{EP}EP1321^EP1321&P{EP}CG2061^EP1537 and P{EP}CG11756^EP1610

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

11C-11D

(Fredieu, 1993.12.20)

11C-11D

(determined by in situ hybridisation)

(Fredieu and Mahowald, 1993)

Experimentally Determined Recombination Data

Location

1-33

(FlyBase, 2016)

1-34.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (3)

Bloomington

33551

w^* P{EP}Gtp-bp^G951/FM7h

52359

y¹ w^* Gtp-bp^B P{neoFRT}19A/FM7c, P{GAL4-Kr.C}DC1, P{UAS-GFP.S65T}DC5, sn⁺

VDRC

v14877

w¹¹¹⁸; P{GD6482}v14877/TM3

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (67)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

LD25651

Other clones

FI05231

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0010391

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0010391

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

47251

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Fredieu and Mahowald, 1993)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: Gtp-bp CG2522

(Bayraktaroglu, 2000.4.7)

Source for merge of: Gtp-bp BEST:CK00309

(FlyBase, 1996-)

Additional comments

Source for merge of Gtp-bp BEST:CK00309 was sequence comparison ( date:030820 ).

(FlyBase, 1996-)

Other Comments

Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis.

(Kopczynski et al., 1998)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

47251

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9U5L1

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010391

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0010391

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Gtp-bp_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2522

Flygut - An atlas of the Drosophila adult midgut

FBgn0010391

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

47251

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC007993

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG2522

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Protein

modMine - A data warehouse for the modENCODE project

FBgn0010391

Linkouts

BioGRID - A database of protein and genetic interactions.

70718

DroID - A comprehensive database of gene and protein interactions.

FBgn0010391

DRSC - Results frm RNAi screens

FBgn0010391

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0010391

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2522-RA

FlyMine - An integrated database for Drosophila genomics

FBgn0010391

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

47251

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Protein export

MIST (protein-protein) - An integrated Molecular Interaction Database

Gtp-bp

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

BEST:CK00309

CG2522

(Hosono et al., 2015, Haelterman et al., 2014, Jaspers et al., 2012, Cammarato et al., 2011, Seinen et al., 2010, Cermelli et al., 2006, Abrams and Andrew, 2005)

CK00309

(Kopczynski et al., 1998)

GTP-bp

(Cermelli et al., 2006, Loop et al., 2004)

Gtp-bp

(Aradska et al., 2015, Haelterman et al., 2014, Kwon et al., 2013, Yamamoto et al., 2013-, Japanese National Institute of Genetics, 2012.5.21, Chung et al., 2011, Friedman et al., 2011, Avet-Rochex et al., 2010, Babenko et al., 2009, Tan et al., 2009, Ranade et al., 2008, Moussian et al., 2005)

SrpRα

(Fox et al., 2010, Abrams and Andrew, 2005)

mAb 13D5

(Fredieu and Mahowald, 1993)

Name Synonyms

GTP binding protein

(Cermelli et al., 2006)

GTP-binding protein

(Jaspers et al., 2012, Cammarato et al., 2011, Fredieu, 1993.12.20)

Secondary FlyBase IDs

FBgn0025711
FBgn0030267

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (50)

Report Sections

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