βν, betaInt-nu, βInt-ν, βν integrin, βv
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.44
Gene model reviewed during 6.02
799 (aa); 130 (kD observed)
Heterodimer of an alpha and a beta subunit. Interacts with scb/alpha-PS3.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Itgbn using the Feature Mapper tool.
βInt-ν protein is found exclusively in the developing midgut endoderm in embryos. Unlike the mRNA, there is no gradient of βInt-ν protein expression in the midgut. In larvae, expression is observed in the midgut imaginal islands, in the gastric caecae, and in the hindgut imaginal ring. Low levels are observed in the proventriculus.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Itgbn in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila Integrin beta subunit gene, Acc. No. L13305. Probable Intron in Drosophila integrin gene.
Embryos transheterozygous for deficiencies that remove βInt-ν develop a normal midgut.