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Gene Dmel\RpS9

General Information
Symbol	Dmel\RpS9	Species	D. melanogaster
Name	Ribosomal protein S9	Annotation symbol	CG3395
Feature type	protein_coding_gene	FlyBase ID	FBgn0010408
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67B11-67B11	Sequence location	3L:9,502,893..9,504,631 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein S9 is referred to in FlyBase by the symbol Dmel\RpS9 (CG3395, FBgn0010408). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization. 9 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: RNA-binding S4 domain; Ribosomal protein S4, conserved site; Ribosomal protein S4/S9; Ribosomal protein S4/S9, N-terminal; Ribosomal protein S4/S9, eukaryotic/archaeal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Gene sequence location is 3L:9502990..9504631.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Transcripts RpS9-RE Polypeptides RpS9-PE
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67B11-67B11   Limits computationally determined from genome sequence between P{EP}Hsp26EP3336&P{EP}Hsp26EP3315 and P{PZ}fry02240
Experimentally Determined Cytological Location
Cytogenetic map Notes References 69-69     (Zhang, 1992.12.4)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpS9 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Gene model reviewed during 5.51 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpS9-RA FBtr0076423  NM_079280   734   195 RpS9-RB FBtr0076424  NM_168351   917   137 RpS9-RD FBtr0076425  NM_168350   706   195 RpS9-RE FBtr0342577     803   195
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpS9-PA   FBpp0076152   22.6   195   11.27     NP_524004   AAF50249 RpS9-PB   FBpp0076153   16.3   137   11.33     NP_729507   AAF50250 RpS9-PD   FBpp0076154   22.6   195   11.27     NP_729506   AAN11946 RpS9-PE   FBpp0309532   22.6   195   11.27
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S4, conserved site (IPR018079) Ribosomal protein S4/S9, N-terminal (IPR001912) RNA-binding S4 domain (IPR002942) Ribosomal protein S4/S9, eukaryotic/archaeal (IPR005710) Ribosomal protein S4/S9 (IPR022801)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201318   AA201770   AA202493   AA246202   AA263270   AA263469   AA263551   AA264144   AA392693   AA392944   AA438348   AA438359   AA440841   AA441307   AA695298   AA696378   AA696842   AA696870   AA697580   AA801729   AA802150   AA802629   AA802631   AA803100   AA803208   AA803268   AA803352   AA803806   AA817231   AA821177   AA941294   AA941295   AA941456   AA941521   AA941769   AA950186   AA950489   AA950619   AA951766   AA952262   AA978482   AA978620   AE014296 AAF50249   AE014296 AAF50250   AE014296 AAN11946   AI061867   AI062362   AI063529   AI063666   AI064012   AI106871   AI107514   AI108877   AI109803   AI109885   AI110144   AI113420   AI134381   AI135044   AI238430   AI238457   AI257555   AI258282   AI258730   AI259080   AI259902   AI260101   AI292499   AI292940   AI294334   AI295080   AI296385   AI297026   AI297365   AI297475   AI297847   AI386906   AI386931   AI389449   AI402912   AI402920   AI404491   AI405564   AI455637   AI456468   AI457006   AI511984   AI512597   AI514653   AI514966   AI518045   AI518564   AI519938   AI520462   AI544330   AK340007   AW943120   AY061396 AAL28944   AY231798   AY232021   AY431675   AY439726   BE978960   BF491912   BF492110   BF496043   BF503775   BF505658   BG634673   BG634783   BG635474   BG635507   BG635526   BG635812   BG636436   BG636575   BG636783   BG637339   BG637357   BG637499   BG637637   BG638500   BG638711   BG640352   BG640445   BG640989   BG641165   BG641424   BI161897   BI162542   BI162585   BI163522   BI163611   BI165690   BI165962   BI166148   BI167227   BI168216   BI168320   BI168683   BI168939   BI169167   BI171443   BI171963   BI172912   BI212764   BI213130   BI214387   BI215920   BI216621   BI227992   BI229404   BI229956   BI230130   BI230802   BI231084   BI232100   BI234040   BI234404   BI234772   BI235259   BI238720   BI239169   BI240189   BI240254   BI242040   BI242191   BI242221   BI243419   BI243818   BI351637   BI351641   BI351735   BI351866   BI352022   BI352053   BI352116   BI352127   BI352333   BI352636   BI352707   BI352778   BI352819   BI353228   BI353260   BI353321   BI353429   BI353514   BI353595   BI353623   BI353779   BI354155   BI354498   BI354516   BI354594   BI354695   BI354793   BI354807   BI354847   BI354873   BI355235   BI355265   BI355458   BI356206   BI356326   BI357198   BI358419   BI362593   BI364770   BI366858   BI367244   BI367452   BI367479   BI368576   BI368853   BI368940   BI369027   BI369263   BI370697   BI371277   BI373412   BI373622   BI375329   BI483439   BI483614   BI484769   BI563363   BI563509   BI564057   BI564239   BI564660   BI564835   BI565214   BI565284   BI565624   BI565736   BI565743   BI566214   BI566399   BI566632   BI566931   BI567346   BI567620   BI567998   BI568201   BI569889   BI570001   BI570317   BI571186   BI571567   BI572651   BI572657   BI572674   BI572691   BI572953   BI573082   BI574377   BI574464   BI575104   BI575885   BI576100   BI576174   BI576218   BI576237   BI576428   BI576734   BI577607   BI577996   BI578319   BI579619   BI581556   BI581576   BI581988   BI582213   BI582634   BI584049   BI584575   BI584586   BI584703   BI585529   BI586113   BI586135   BI586234   BI586818   BI586820   BI586834   BI587014   BI587085   BI588517   BI589075   BI589115   BI589153   BI589373   BI589720   BI591527   BI591708   BI591917   BI592552   BI592612   BI592930   BI604250   BI605004   BI606111   BI606476   BI606749   BI606824   BI607114   BI607230   BI607349   BI607499   BI607596   BI607639   BI607870   BI608320   BI608453   BI608492   BI609296   BI609634   BI611308   BI613674   BI614405   BI614609   BI616138   BI616240   BI616773   BI618705   BI618780   BI618840   BI619471   BI619976   BI620631   BI620681   BI621006   BI621246   BI622050   BI622240   BI622254   BI622574   BI622977   BI623902   BI624172   BI624182   BI624532   BI625551   BI626069   BI626124   BI627022   BI627050   BI627427   BI627645   BI627804   BI628164   BI628213   BI628295   BI628393   BI628869   BI628992   BI629418   BI629653   BI629674   BI629856   BI629970   BI630416   BI630488   BI631445   BI631457   BI631534   BI631980   BI632481   BI633034   BI633182   BI633238   BI633479   BI634113   BI634162   BI634232   BI634277   BI634307   BI634497   BI634632   BI634712   BI634732   BI635123   BI635272   BI635421   BI636150   BI636421   BI636592   BI636640   BI636926   BI636939   BI637644   BI638499   BI638575   BI638874   BI639391   BI639493   BI639564   BI639793   BI639823   BI639885   BI640005   BI640228   BI640418   BI640622   BI640645   BI641684   BP540421   BP541260   BP541302   BP542952   BP543463   BP544274   BP544451   BP544891   BP545061   BP545655   BP546673   BP546954   BP547262   BP548376   BP548420   BP550288   BP552316   BP552345   BP554274   BP555530   BP555826   BP556391   BP557005   BP559041   BT023134   BT088955   CA804787   CK131613   CK131835   CK132204   CK132836   CK604591   CK604592   CK658583   CK658790   CK659588   CK659816   CK660613   CK661504   CK661676   CK662094   CK662234   CK662247   CO152934   CO153998   CO154527   CO154689   CO181101   CO183314   CO183746   CO184935   CO189667   CO191392   CO192856   CO193688   CO193875   CO194004   CO195640   CO262586   CO264658   CO280693   CO288383   CO290995   CO296670   CO302528   CO315804   CO329580   CO333339   CO335709   CO336593   CO337396   CO337655   CO337828   CO338036   CR937977   CR938092   CR938248   CR938439   CR938484   CR938656   DN154512   DQ440051   EC057004   EC066420   EC069402   EC070464   EC072447   EC074318   EC075740   EC078842   EC196503   EC202057   EC216707   EC230933   EC233884   EC234426   EC242169   EC262630   EC262833   EC263343   EC263611   EC263784   EC264110   EC265101   EC265192   EC265224   EC265246   EC266415   EC267079   EL871381   EL873019   EL881290   EL882410   EL882526   EL882656   EL883743   EL884397   EL885943   EL886170   EL886275   EV575150   EV576213   EV576292   EV576724   EV576756   EV577502   EV578013   EV578853   EV579236   EV579490   EV579666   EV579942   EV580043   EV580077   EV580327   EV580443   EV580585   EV580698   EV581279   EV581623   EV581690   EV581819   EV582088   EV582231   EV582605   EV583984   EV584527   EV584842   EV585136   EV585294   EV588901   EV589274   EV590477   EV590906   EV591426   EV592556   EV593288   EV593310   EV593354   EV593396   EV593440   EV594021   EV594230   EV594470   EV594536   EV594901   EV595366   EV595717   EV596241   EV598366   EV598509   EV598815   EV598826   GH943198   GH944472   GH945546   GH945694   GH946606   GH950608   GH951247   GH951841   GH953060   GH954226   GH960036   GH961537   GH961680   GH968173   GH970639   GH971988   GH973030   GH978837   GH981037   GH982788   GH984473   X69677 CAB41492
UniProtKB/Swiss-Prot	P55935
UniProtKB/TrEMBL	Q95RG1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
ribosome inferred from direct assay (Alonso and Santaren, 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1046 central nervous system, larvae L3    528 central nervous system, pupae P8    268 head, virgin 1-day female    330 head, virgin 4-day female    529 head, virgin 20-day female    775 head, mated 1-day female    293 head, mated 4-day female    443 head, mated 20-day female    544 head, mated 1-day male    271 head, mated 4-day male    289 head, mated 20-day male    483 salivary gland, larvae L3 wandering    525 salivary gland, white prepupae    758 digestive system, larvae L3 wandering    484 digestive system, 1-day adult    579 digestive system, 4-day adult    458 digestive system, 20-day adult    562 fat body, larvae L3 wandering    299 fat body, white prepupae    274 fat body, pupae P8    631 carcass, larvae L3 wandering    674 carcass, 1-day adult    288 carcass, 4-day adult    334 carcass, 20-day adult    392 ovary, virgin 4-day female    714 ovary, mated 4-day female    635 testis, mated 4-day male    316 accessory gland, mated 4-day male    503 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1046) central nervous system, larvae L3  (528) central nervous system, pupae P8  (268) head, virgin 1-day female  (330) head, virgin 4-day female  (529) head, virgin 20-day female  (775) head, mated 1-day female  (293) head, mated 4-day female  (443) head, mated 20-day female  (544) head, mated 1-day male  (271) head, mated 4-day male  (289) head, mated 20-day male  (483) salivary gland, larvae L3 wandering  (525) salivary gland, white prepupae  (758) digestive system, larvae L3 wandering  (484) digestive system, 1-day adult  (579) digestive system, 4-day adult  (458) digestive system, 20-day adult  (562) fat body, larvae L3 wandering  (299) fat body, white prepupae  (274) fat body, pupae P8  (631) carcass, larvae L3 wandering  (674) carcass, 1-day adult  (288) carcass, 4-day adult  (334) carcass, 20-day adult  (392) ovary, virgin 4-day female  (714) ovary, mated 4-day female  (635) testis, mated 4-day male  (316) accessory gland, mated 4-day male  (503) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1046) central nervous system, larvae L3  (528) central nervous system, pupae P8  (268) head, virgin 1-day female  (330) head, virgin 4-day female  (529) head, virgin 20-day female  (775) head, mated 1-day female  (293) head, mated 4-day female  (443) head, mated 20-day female  (544) head, mated 1-day male  (271) head, mated 4-day male  (289) head, mated 20-day male  (483) salivary gland, larvae L3 wandering  (525) salivary gland, white prepupae  (758) digestive system, larvae L3 wandering  (484) digestive system, 1-day adult  (579) digestive system, 4-day adult  (458) digestive system, 20-day adult  (562) fat body, larvae L3 wandering  (299) fat body, white prepupae  (274) fat body, pupae P8  (631) carcass, larvae L3 wandering  (674) carcass, 1-day adult  (288) carcass, 4-day adult  (334) carcass, 20-day adult  (392) ovary, virgin 4-day female  (714) ovary, mated 4-day female  (635) testis, mated 4-day male  (316) accessory gland, mated 4-day male  (503) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1046 central nervous system, larvae L3    528 central nervous system, pupae P8    268 head, virgin 1-day female    330 head, virgin 4-day female    529 head, virgin 20-day female    775 head, mated 1-day female    293 head, mated 4-day female    443 head, mated 20-day female    544 head, mated 1-day male    271 head, mated 4-day male    289 head, mated 20-day male    483 salivary gland, larvae L3 wandering    525 salivary gland, white prepupae    758 digestive system, larvae L3 wandering    484 digestive system, 1-day adult    579 digestive system, 4-day adult    458 digestive system, 20-day adult    562 fat body, larvae L3 wandering    299 fat body, white prepupae    274 fat body, pupae P8    631 carcass, larvae L3 wandering    674 carcass, 1-day adult    288 carcass, 4-day adult    334 carcass, 20-day adult    392 ovary, virgin 4-day female    714 ovary, mated 4-day female    635 testis, mated 4-day male    316 accessory gland, mated 4-day male    503 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1046 central nervous system, larvae L3    528 central nervous system, pupae P8    268 head, virgin 1-day female    330 head, virgin 4-day female    529 head, virgin 20-day female    775 head, mated 1-day female    293 head, mated 4-day female    443 head, mated 20-day female    544 head, mated 1-day male    271 head, mated 4-day male    289 head, mated 20-day male    483 salivary gland, larvae L3 wandering    525 salivary gland, white prepupae    758 digestive system, larvae L3 wandering    484 digestive system, 1-day adult    579 digestive system, 4-day adult    458 digestive system, 20-day adult    562 fat body, larvae L3 wandering    299 fat body, white prepupae    274 fat body, pupae P8    631 carcass, larvae L3 wandering    674 carcass, 1-day adult    288 carcass, 4-day adult    334 carcass, 20-day adult    392 ovary, virgin 4-day female    714 ovary, mated 4-day female    635 testis, mated 4-day male    316 accessory gland, mated 4-day male    503 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1046) central nervous system, larvae L3  (528) central nervous system, pupae P8  (268) head, virgin 1-day female  (330) head, virgin 4-day female  (529) head, virgin 20-day female  (775) head, mated 1-day female  (293) head, mated 4-day female  (443) head, mated 20-day female  (544) head, mated 1-day male  (271) head, mated 4-day male  (289) head, mated 20-day male  (483) salivary gland, larvae L3 wandering  (525) salivary gland, white prepupae  (758) digestive system, larvae L3 wandering  (484) digestive system, 1-day adult  (579) digestive system, 4-day adult  (458) digestive system, 20-day adult  (562) fat body, larvae L3 wandering  (299) fat body, white prepupae  (274) fat body, pupae P8  (631) carcass, larvae L3 wandering  (674) carcass, 1-day adult  (288) carcass, 4-day adult  (334) carcass, 20-day adult  (392) ovary, virgin 4-day female  (714) ovary, mated 4-day female  (635) testis, mated 4-day male  (316) accessory gland, mated 4-day male  (503) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (1046) central nervous system, larvae L3  (528) central nervous system, pupae P8  (268) head, virgin 1-day female  (330) head, virgin 4-day female  (529) head, virgin 20-day female  (775) head, mated 1-day female  (293) head, mated 4-day female  (443) head, mated 20-day female  (544) head, mated 1-day male  (271) head, mated 4-day male  (289) head, mated 20-day male  (483) salivary gland, larvae L3 wandering  (525) salivary gland, white prepupae  (758) digestive system, larvae L3 wandering  (484) digestive system, 1-day adult  (579) digestive system, 4-day adult  (458) digestive system, 20-day adult  (562) fat body, larvae L3 wandering  (299) fat body, white prepupae  (274) fat body, pupae P8  (631) carcass, larvae L3 wandering  (674) carcass, 1-day adult  (288) carcass, 4-day adult  (334) carcass, 20-day adult  (392) ovary, virgin 4-day female  (714) ovary, mated 4-day female  (635) testis, mated 4-day male  (316) accessory gland, mated 4-day male  (503) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1046 central nervous system, larvae L3    528 central nervous system, pupae P8    268 head, virgin 1-day female    330 head, virgin 4-day female    529 head, virgin 20-day female    775 head, mated 1-day female    293 head, mated 4-day female    443 head, mated 20-day female    544 head, mated 1-day male    271 head, mated 4-day male    289 head, mated 20-day male    483 salivary gland, larvae L3 wandering    525 salivary gland, white prepupae    758 digestive system, larvae L3 wandering    484 digestive system, 1-day adult    579 digestive system, 4-day adult    458 digestive system, 20-day adult    562 fat body, larvae L3 wandering    299 fat body, white prepupae    274 fat body, pupae P8    631 carcass, larvae L3 wandering    674 carcass, 1-day adult    288 carcass, 4-day adult    334 carcass, 20-day adult    392 ovary, virgin 4-day female    714 ovary, mated 4-day female    635 testis, mated 4-day male    316 accessory gland, mated 4-day male    503 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1818 embryo 02-04hr    2802 embryo 04-06hr    2848 embryo 06-08hr    3158 embryo 08-10hr    3638 embryo 10-12hr    5264 embryo 12-14hr    2480 embryo 14-16hr    3312 embryo 16-18hr    2605 embryo 18-20hr    2856 embryo 20-22hr    2769 embryo 22-24hr    2220 larva L1    3272 larva L2    2628 larva L3 12hr old    2035 larva L3 puffstage 1-2    1610 larva L3 puffstage 3-6    1600 larva L3 puffstage 7-9    1593 white prepupae new    1511 white prepupae 12hr    1354 white prepupae 24hr    1275 pupae 2d postWPP    1164 pupae 3d postWPP    974 pupae 4d postWPP    1211 adult male 01day    769 adult male 05day    711 adult male 30day    945 adult female 01day    2310 adult female 05day    1825 adult female 30day    1963 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1818) embryo 02-04hr  (2802) embryo 04-06hr  (2848) embryo 06-08hr  (3158) embryo 08-10hr  (3638) embryo 10-12hr  (5264) embryo 12-14hr  (2480) embryo 14-16hr  (3312) embryo 16-18hr  (2605) embryo 18-20hr  (2856) embryo 20-22hr  (2769) embryo 22-24hr  (2220) larva L1  (3272) larva L2  (2628) larva L3 12hr old  (2035) larva L3 puffstage 1-2  (1610) larva L3 puffstage 3-6  (1600) larva L3 puffstage 7-9  (1593) white prepupae new  (1511) white prepupae 12hr  (1354) white prepupae 24hr  (1275) pupae 2d postWPP  (1164) pupae 3d postWPP  (974) pupae 4d postWPP  (1211) adult male 01day  (769) adult male 05day  (711) adult male 30day  (945) adult female 01day  (2310) adult female 05day  (1825) adult female 30day  (1963) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1818) embryo 02-04hr  (2802) embryo 04-06hr  (2848) embryo 06-08hr  (3158) embryo 08-10hr  (3638) embryo 10-12hr  (5264) embryo 12-14hr  (2480) embryo 14-16hr  (3312) embryo 16-18hr  (2605) embryo 18-20hr  (2856) embryo 20-22hr  (2769) embryo 22-24hr  (2220) larva L1  (3272) larva L2  (2628) larva L3 12hr old  (2035) larva L3 puffstage 1-2  (1610) larva L3 puffstage 3-6  (1600) larva L3 puffstage 7-9  (1593) white prepupae new  (1511) white prepupae 12hr  (1354) white prepupae 24hr  (1275) pupae 2d postWPP  (1164) pupae 3d postWPP  (974) pupae 4d postWPP  (1211) adult male 01day  (769) adult male 05day  (711) adult male 30day  (945) adult female 01day  (2310) adult female 05day  (1825) adult female 30day  (1963) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1818 embryo 02-04hr    2802 embryo 04-06hr    2848 embryo 06-08hr    3158 embryo 08-10hr    3638 embryo 10-12hr    5264 embryo 12-14hr    2480 embryo 14-16hr    3312 embryo 16-18hr    2605 embryo 18-20hr    2856 embryo 20-22hr    2769 embryo 22-24hr    2220 larva L1    3272 larva L2    2628 larva L3 12hr old    2035 larva L3 puffstage 1-2    1610 larva L3 puffstage 3-6    1600 larva L3 puffstage 7-9    1593 white prepupae new    1511 white prepupae 12hr    1354 white prepupae 24hr    1275 pupae 2d postWPP    1164 pupae 3d postWPP    974 pupae 4d postWPP    1211 adult male 01day    769 adult male 05day    711 adult male 30day    945 adult female 01day    2310 adult female 05day    1825 adult female 30day    1963 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1818 embryo 02-04hr    2802 embryo 04-06hr    2848 embryo 06-08hr    3158 embryo 08-10hr    3638 embryo 10-12hr    5264 embryo 12-14hr    2480 embryo 14-16hr    3312 embryo 16-18hr    2605 embryo 18-20hr    2856 embryo 20-22hr    2769 embryo 22-24hr    2220 larva L1    3272 larva L2    2628 larva L3 12hr old    2035 larva L3 puffstage 1-2    1610 larva L3 puffstage 3-6    1600 larva L3 puffstage 7-9    1593 white prepupae new    1511 white prepupae 12hr    1354 white prepupae 24hr    1275 pupae 2d postWPP    1164 pupae 3d postWPP    974 pupae 4d postWPP    1211 adult male 01day    769 adult male 05day    711 adult male 30day    945 adult female 01day    2310 adult female 05day    1825 adult female 30day    1963 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1818) embryo 02-04hr  (2802) embryo 04-06hr  (2848) embryo 06-08hr  (3158) embryo 08-10hr  (3638) embryo 10-12hr  (5264) embryo 12-14hr  (2480) embryo 14-16hr  (3312) embryo 16-18hr  (2605) embryo 18-20hr  (2856) embryo 20-22hr  (2769) embryo 22-24hr  (2220) larva L1  (3272) larva L2  (2628) larva L3 12hr old  (2035) larva L3 puffstage 1-2  (1610) larva L3 puffstage 3-6  (1600) larva L3 puffstage 7-9  (1593) white prepupae new  (1511) white prepupae 12hr  (1354) white prepupae 24hr  (1275) pupae 2d postWPP  (1164) pupae 3d postWPP  (974) pupae 4d postWPP  (1211) adult male 01day  (769) adult male 05day  (711) adult male 30day  (945) adult female 01day  (2310) adult female 05day  (1825) adult female 30day  (1963) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (1818) embryo 02-04hr  (2802) embryo 04-06hr  (2848) embryo 06-08hr  (3158) embryo 08-10hr  (3638) embryo 10-12hr  (5264) embryo 12-14hr  (2480) embryo 14-16hr  (3312) embryo 16-18hr  (2605) embryo 18-20hr  (2856) embryo 20-22hr  (2769) embryo 22-24hr  (2220) larva L1  (3272) larva L2  (2628) larva L3 12hr old  (2035) larva L3 puffstage 1-2  (1610) larva L3 puffstage 3-6  (1600) larva L3 puffstage 7-9  (1593) white prepupae new  (1511) white prepupae 12hr  (1354) white prepupae 24hr  (1275) pupae 2d postWPP  (1164) pupae 3d postWPP  (974) pupae 4d postWPP  (1211) adult male 01day  (769) adult male 05day  (711) adult male 30day  (945) adult female 01day  (2310) adult female 05day  (1825) adult female 30day  (1963) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1818 embryo 02-04hr    2802 embryo 04-06hr    2848 embryo 06-08hr    3158 embryo 08-10hr    3638 embryo 10-12hr    5264 embryo 12-14hr    2480 embryo 14-16hr    3312 embryo 16-18hr    2605 embryo 18-20hr    2856 embryo 20-22hr    2769 embryo 22-24hr    2220 larva L1    3272 larva L2    2628 larva L3 12hr old    2035 larva L3 puffstage 1-2    1610 larva L3 puffstage 3-6    1600 larva L3 puffstage 7-9    1593 white prepupae new    1511 white prepupae 12hr    1354 white prepupae 24hr    1275 pupae 2d postWPP    1164 pupae 3d postWPP    974 pupae 4d postWPP    1211 adult male 01day    769 adult male 05day    711 adult male 30day    945 adult female 01day    2310 adult female 05day    1825 adult female 30day    1963 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1323 Schneider line 2 Sg4    2091 embryonic 1182-4H    991 embryonic GM2    629 embryonic Kc167    1513 embryonic S1    919 embryonic S3    765 leg disc CME L1    1746 wing disc CME-W2    954 wing disc ML-DmD8    2733 wing disc ML-DmD9    1553 wing disc ML-DmD16-c3    920 wing disc ML-DmD21    3396 wing disc ML-DmD32    1382 haltere disc ML-DmD17-c3    898 eye-antennal disc ML-DmD11    1863 antennal disc ML-DmD20-c5    2262 mixed discs ML-DmD4-c1    1852 CNS ML-DmBG1-c1    1152 CNS ML-DmBG2-c2    1213 tumorous blood cells mbn2    761 ovary fGS/OSS    645 ovary OSC    402 ovary OSS    224 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (1323) Schneider line 2 Sg4  (2091) embryonic 1182-4H  (991) embryonic GM2  (629) embryonic Kc167  (1513) embryonic S1  (919) embryonic S3  (765) leg disc CME L1  (1746) wing disc CME-W2  (954) wing disc ML-DmD8  (2733) wing disc ML-DmD9  (1553) wing disc ML-DmD16-c3  (920) wing disc ML-DmD21  (3396) wing disc ML-DmD32  (1382) haltere disc ML-DmD17-c3  (898) eye-antennal disc ML-DmD11  (1863) antennal disc ML-DmD20-c5  (2262) mixed discs ML-DmD4-c1  (1852) CNS ML-DmBG1-c1  (1152) CNS ML-DmBG2-c2  (1213) tumorous blood cells mbn2  (761) ovary fGS/OSS  (645) ovary OSC  (402) ovary OSS  (224) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (1323) Schneider line 2 Sg4  (2091) embryonic 1182-4H  (991) embryonic GM2  (629) embryonic Kc167  (1513) embryonic S1  (919) embryonic S3  (765) leg disc CME L1  (1746) wing disc CME-W2  (954) wing disc ML-DmD8  (2733) wing disc ML-DmD9  (1553) wing disc ML-DmD16-c3  (920) wing disc ML-DmD21  (3396) wing disc ML-DmD32  (1382) haltere disc ML-DmD17-c3  (898) eye-antennal disc ML-DmD11  (1863) antennal disc ML-DmD20-c5  (2262) mixed discs ML-DmD4-c1  (1852) CNS ML-DmBG1-c1  (1152) CNS ML-DmBG2-c2  (1213) tumorous blood cells mbn2  (761) ovary fGS/OSS  (645) ovary OSC  (402) ovary OSS  (224) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1323 Schneider line 2 Sg4    2091 embryonic 1182-4H    991 embryonic GM2    629 embryonic Kc167    1513 embryonic S1    919 embryonic S3    765 leg disc CME L1    1746 wing disc CME-W2    954 wing disc ML-DmD8    2733 wing disc ML-DmD9    1553 wing disc ML-DmD16-c3    920 wing disc ML-DmD21    3396 wing disc ML-DmD32    1382 haltere disc ML-DmD17-c3    898 eye-antennal disc ML-DmD11    1863 antennal disc ML-DmD20-c5    2262 mixed discs ML-DmD4-c1    1852 CNS ML-DmBG1-c1    1152 CNS ML-DmBG2-c2    1213 tumorous blood cells mbn2    761 ovary fGS/OSS    645 ovary OSC    402 ovary OSS    224 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1323 Schneider line 2 Sg4    2091 embryonic 1182-4H    991 embryonic GM2    629 embryonic Kc167    1513 embryonic S1    919 embryonic S3    765 leg disc CME L1    1746 wing disc CME-W2    954 wing disc ML-DmD8    2733 wing disc ML-DmD9    1553 wing disc ML-DmD16-c3    920 wing disc ML-DmD21    3396 wing disc ML-DmD32    1382 haltere disc ML-DmD17-c3    898 eye-antennal disc ML-DmD11    1863 antennal disc ML-DmD20-c5    2262 mixed discs ML-DmD4-c1    1852 CNS ML-DmBG1-c1    1152 CNS ML-DmBG2-c2    1213 tumorous blood cells mbn2    761 ovary fGS/OSS    645 ovary OSC    402 ovary OSS    224 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (1323) Schneider line 2 Sg4  (2091) embryonic 1182-4H  (991) embryonic GM2  (629) embryonic Kc167  (1513) embryonic S1  (919) embryonic S3  (765) leg disc CME L1  (1746) wing disc CME-W2  (954) wing disc ML-DmD8  (2733) wing disc ML-DmD9  (1553) wing disc ML-DmD16-c3  (920) wing disc ML-DmD21  (3396) wing disc ML-DmD32  (1382) haltere disc ML-DmD17-c3  (898) eye-antennal disc ML-DmD11  (1863) antennal disc ML-DmD20-c5  (2262) mixed discs ML-DmD4-c1  (1852) CNS ML-DmBG1-c1  (1152) CNS ML-DmBG2-c2  (1213) tumorous blood cells mbn2  (761) ovary fGS/OSS  (645) ovary OSC  (402) ovary OSS  (224) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (1323) Schneider line 2 Sg4  (2091) embryonic 1182-4H  (991) embryonic GM2  (629) embryonic Kc167  (1513) embryonic S1  (919) embryonic S3  (765) leg disc CME L1  (1746) wing disc CME-W2  (954) wing disc ML-DmD8  (2733) wing disc ML-DmD9  (1553) wing disc ML-DmD16-c3  (920) wing disc ML-DmD21  (3396) wing disc ML-DmD32  (1382) haltere disc ML-DmD17-c3  (898) eye-antennal disc ML-DmD11  (1863) antennal disc ML-DmD20-c5  (2262) mixed discs ML-DmD4-c1  (1852) CNS ML-DmBG1-c1  (1152) CNS ML-DmBG2-c2  (1213) tumorous blood cells mbn2  (761) ovary fGS/OSS  (645) ovary OSC  (402) ovary OSS  (224) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1323 Schneider line 2 Sg4    2091 embryonic 1182-4H    991 embryonic GM2    629 embryonic Kc167    1513 embryonic S1    919 embryonic S3    765 leg disc CME L1    1746 wing disc CME-W2    954 wing disc ML-DmD8    2733 wing disc ML-DmD9    1553 wing disc ML-DmD16-c3    920 wing disc ML-DmD21    3396 wing disc ML-DmD32    1382 haltere disc ML-DmD17-c3    898 eye-antennal disc ML-DmD11    1863 antennal disc ML-DmD20-c5    2262 mixed discs ML-DmD4-c1    1852 CNS ML-DmBG1-c1    1152 CNS ML-DmBG2-c2    1213 tumorous blood cells mbn2    761 ovary fGS/OSS    645 ovary OSC    402 ovary OSS    224 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    558 cold shock, 4-day adult    420 heat shock, 4-day adult    1166 Cadmium 50 mM 6 hrs, larvae L3    1383 Cadmium 50 mM 12 hrs, larvae L3    963 Cadmium 50 mM 48 hrs, 4-day adult    755 Cadmium 100 mM 48 hrs, 4-day adult    619 Copper 0.5 mM 12 hrs, larvae L3    666 Copper 15 mM 48 hrs, 4-day adult    210 Zinc 5 mM 12 hrs, larvae L3    540 Zinc 4.5 mM 48 hrs, 4-day adult    281 Ethanol 2.5% 3 hrs, larvae L3    1342 Ethanol 5% 3 hrs, larvae L3    937 Ethanol 10% 3 hrs, larvae L3    1051 Caffeine 1.5 mg/ml 4 hrs, larvae L3    894 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    707 Caffeine 25 mg/ml 48 hrs, 4-day adult    430 Paraquat 5 mM 48 hrs, 4-day adult    919 Paraquat 10 mM 48 hrs, 4-day adult    1149 Rotenone 2 μg 12 hrs, larvae L3    1047 Rotenone 8 μg 12 hrs, larvae L3    1354 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (558) cold shock, 4-day adult  (420) heat shock, 4-day adult  (1166) Cadmium 50 mM 6 hrs, larvae L3  (1383) Cadmium 50 mM 12 hrs, larvae L3  (963) Cadmium 50 mM 48 hrs, 4-day adult  (755) Cadmium 100 mM 48 hrs, 4-day adult  (619) Copper 0.5 mM 12 hrs, larvae L3  (666) Copper 15 mM 48 hrs, 4-day adult  (210) Zinc 5 mM 12 hrs, larvae L3  (540) Zinc 4.5 mM 48 hrs, 4-day adult  (281) Ethanol 2.5% 3 hrs, larvae L3  (1342) Ethanol 5% 3 hrs, larvae L3  (937) Ethanol 10% 3 hrs, larvae L3  (1051) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (894) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (707) Caffeine 25 mg/ml 48 hrs, 4-day adult  (430) Paraquat 5 mM 48 hrs, 4-day adult  (919) Paraquat 10 mM 48 hrs, 4-day adult  (1149) Rotenone 2 μg 12 hrs, larvae L3  (1047) Rotenone 8 μg 12 hrs, larvae L3  (1354) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (558) cold shock, 4-day adult  (420) heat shock, 4-day adult  (1166) Cadmium 50 mM 6 hrs, larvae L3  (1383) Cadmium 50 mM 12 hrs, larvae L3  (963) Cadmium 50 mM 48 hrs, 4-day adult  (755) Cadmium 100 mM 48 hrs, 4-day adult  (619) Copper 0.5 mM 12 hrs, larvae L3  (666) Copper 15 mM 48 hrs, 4-day adult  (210) Zinc 5 mM 12 hrs, larvae L3  (540) Zinc 4.5 mM 48 hrs, 4-day adult  (281) Ethanol 2.5% 3 hrs, larvae L3  (1342) Ethanol 5% 3 hrs, larvae L3  (937) Ethanol 10% 3 hrs, larvae L3  (1051) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (894) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (707) Caffeine 25 mg/ml 48 hrs, 4-day adult  (430) Paraquat 5 mM 48 hrs, 4-day adult  (919) Paraquat 10 mM 48 hrs, 4-day adult  (1149) Rotenone 2 μg 12 hrs, larvae L3  (1047) Rotenone 8 μg 12 hrs, larvae L3  (1354) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    558 cold shock, 4-day adult    420 heat shock, 4-day adult    1166 Cadmium 50 mM 6 hrs, larvae L3    1383 Cadmium 50 mM 12 hrs, larvae L3    963 Cadmium 50 mM 48 hrs, 4-day adult    755 Cadmium 100 mM 48 hrs, 4-day adult    619 Copper 0.5 mM 12 hrs, larvae L3    666 Copper 15 mM 48 hrs, 4-day adult    210 Zinc 5 mM 12 hrs, larvae L3    540 Zinc 4.5 mM 48 hrs, 4-day adult    281 Ethanol 2.5% 3 hrs, larvae L3    1342 Ethanol 5% 3 hrs, larvae L3    937 Ethanol 10% 3 hrs, larvae L3    1051 Caffeine 1.5 mg/ml 4 hrs, larvae L3    894 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    707 Caffeine 25 mg/ml 48 hrs, 4-day adult    430 Paraquat 5 mM 48 hrs, 4-day adult    919 Paraquat 10 mM 48 hrs, 4-day adult    1149 Rotenone 2 μg 12 hrs, larvae L3    1047 Rotenone 8 μg 12 hrs, larvae L3    1354 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    558 cold shock, 4-day adult    420 heat shock, 4-day adult    1166 Cadmium 50 mM 6 hrs, larvae L3    1383 Cadmium 50 mM 12 hrs, larvae L3    963 Cadmium 50 mM 48 hrs, 4-day adult    755 Cadmium 100 mM 48 hrs, 4-day adult    619 Copper 0.5 mM 12 hrs, larvae L3    666 Copper 15 mM 48 hrs, 4-day adult    210 Zinc 5 mM 12 hrs, larvae L3    540 Zinc 4.5 mM 48 hrs, 4-day adult    281 Ethanol 2.5% 3 hrs, larvae L3    1342 Ethanol 5% 3 hrs, larvae L3    937 Ethanol 10% 3 hrs, larvae L3    1051 Caffeine 1.5 mg/ml 4 hrs, larvae L3    894 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    707 Caffeine 25 mg/ml 48 hrs, 4-day adult    430 Paraquat 5 mM 48 hrs, 4-day adult    919 Paraquat 10 mM 48 hrs, 4-day adult    1149 Rotenone 2 μg 12 hrs, larvae L3    1047 Rotenone 8 μg 12 hrs, larvae L3    1354 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (558) cold shock, 4-day adult  (420) heat shock, 4-day adult  (1166) Cadmium 50 mM 6 hrs, larvae L3  (1383) Cadmium 50 mM 12 hrs, larvae L3  (963) Cadmium 50 mM 48 hrs, 4-day adult  (755) Cadmium 100 mM 48 hrs, 4-day adult  (619) Copper 0.5 mM 12 hrs, larvae L3  (666) Copper 15 mM 48 hrs, 4-day adult  (210) Zinc 5 mM 12 hrs, larvae L3  (540) Zinc 4.5 mM 48 hrs, 4-day adult  (281) Ethanol 2.5% 3 hrs, larvae L3  (1342) Ethanol 5% 3 hrs, larvae L3  (937) Ethanol 10% 3 hrs, larvae L3  (1051) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (894) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (707) Caffeine 25 mg/ml 48 hrs, 4-day adult  (430) Paraquat 5 mM 48 hrs, 4-day adult  (919) Paraquat 10 mM 48 hrs, 4-day adult  (1149) Rotenone 2 μg 12 hrs, larvae L3  (1047) Rotenone 8 μg 12 hrs, larvae L3  (1354) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (558) cold shock, 4-day adult  (420) heat shock, 4-day adult  (1166) Cadmium 50 mM 6 hrs, larvae L3  (1383) Cadmium 50 mM 12 hrs, larvae L3  (963) Cadmium 50 mM 48 hrs, 4-day adult  (755) Cadmium 100 mM 48 hrs, 4-day adult  (619) Copper 0.5 mM 12 hrs, larvae L3  (666) Copper 15 mM 48 hrs, 4-day adult  (210) Zinc 5 mM 12 hrs, larvae L3  (540) Zinc 4.5 mM 48 hrs, 4-day adult  (281) Ethanol 2.5% 3 hrs, larvae L3  (1342) Ethanol 5% 3 hrs, larvae L3  (937) Ethanol 10% 3 hrs, larvae L3  (1051) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (894) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (707) Caffeine 25 mg/ml 48 hrs, 4-day adult  (430) Paraquat 5 mM 48 hrs, 4-day adult  (919) Paraquat 10 mM 48 hrs, 4-day adult  (1149) Rotenone 2 μg 12 hrs, larvae L3  (1047) Rotenone 8 μg 12 hrs, larvae L3  (1354) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    558 cold shock, 4-day adult    420 heat shock, 4-day adult    1166 Cadmium 50 mM 6 hrs, larvae L3    1383 Cadmium 50 mM 12 hrs, larvae L3    963 Cadmium 50 mM 48 hrs, 4-day adult    755 Cadmium 100 mM 48 hrs, 4-day adult    619 Copper 0.5 mM 12 hrs, larvae L3    666 Copper 15 mM 48 hrs, 4-day adult    210 Zinc 5 mM 12 hrs, larvae L3    540 Zinc 4.5 mM 48 hrs, 4-day adult    281 Ethanol 2.5% 3 hrs, larvae L3    1342 Ethanol 5% 3 hrs, larvae L3    937 Ethanol 10% 3 hrs, larvae L3    1051 Caffeine 1.5 mg/ml 4 hrs, larvae L3    894 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    707 Caffeine 25 mg/ml 48 hrs, 4-day adult    430 Paraquat 5 mM 48 hrs, 4-day adult    919 Paraquat 10 mM 48 hrs, 4-day adult    1149 Rotenone 2 μg 12 hrs, larvae L3    1047 Rotenone 8 μg 12 hrs, larvae L3    1354 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_22 mE1_20_mRNA_expression_cluster_01
External Data & Images
Linkouts	BDGP expression data • LD32106 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010408 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3395-RB;CG3395-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable RpS9f03376 Sterility Allele fertile RpS9f03376 Other Phenotypes Allele Minute RpS9EP3299 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of RpS9 Class Mutagen Stocks Known lesion RpS9f03376 piggyBac transposase 2 -- RpS9G7201 P-element activity 1 -- RpS9CPTI000493 piggyBac transposase 0 Yes RpS9CPTI000785 piggyBac transposase 0 Yes RpS9EP3299 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpS9 Class Mutagen Stocks Known lesion RpS9HMS00271 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS9KK108037 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS9dsRNA.cLa in vitro construct - RNAi 0 Yes RpS9GD10484 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6114 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10484} NA P{KK108037} NA P{TRiP.HMS00271} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{UASp-YFP.RabX2.S21N}CG340805 NA PBac{602.P.SVS-1}RpS9CPTI000493 NA PBac{602.P.SVS-1}RpS9CPTI000785 NA PBac{WH}RpS9f03376 NA insertion of mobile activating element P{EP}RpS9EP3299 NA P{EP}RpS9G7201 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
structural constituent of ribosome inferred from direct assay (Alonso and Santaren, 2006)
Biological Process
CV term Evidence References
mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component
CV term Evidence References
ribosome inferred from direct assay (Alonso and Santaren, 2006)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
rRNA binding inferred from electronic annotation with InterPro:IPR001912, InterPro:IPR018079 (FlyBase Curators et al., 2004-) structural constituent of ribosome inferred from sequence or structural similarity with UniProtKB:P29314 (FlyBase, 1992-) non-traceable author statement (Zhang, 1992.12.4, Swiss-Prot Project Members, 1997.2.1)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with UniProtKB:P29314 (FlyBase, 1992-) non-traceable author statement (Zhang, 1992.12.4)
Cellular Component
CV term Evidence References
cytosolic small ribosomal subunit inferred from sequence or structural similarity with UniProtKB:P29314 (FlyBase, 1992-) non-traceable author statement (Zhang, 1992.12.4) ribosome non-traceable author statement (Swiss-Prot Project Members, 1997.2.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
RpS9 - eIF-2α anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpS9 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64500 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010408 DroID - A comprehensive database of gene and protein interactions. • FBgn0010408 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39108
Orthologs
OrthoDB Orthologs (52) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG63V0FZ Dipteran inclusive ortholog search EOG6W0XP8 Insect inclusive ortholog search EOG65X6SG Arthropod inclusive ortholog search EOG6Z8WCS Metazoa inclusive ortholog search EOG6DRP74
Orthologs in Drosophila Species (EOG63V0FZ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RpS9     Drosophila simulans   Dsim\GD12912 Y   Drosophila sechellia   Dsec\GM24860 Y   Drosophila erecta   Dere\GG14025 Y   Drosophila yakuba   Dyak\RpS9 Y   Drosophila ananassae   Dana\GF24655 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA28351 Y   Drosophila persimilis   Dper\GL21280     Drosophila persimilis   Dper\GL20135     Drosophila persimilis   Dper\GL17960 Y   Drosophila willistoni   Dwil\GK17575 Y   Drosophila virilis   Dvir\GJ13353 Y   Drosophila mojavensis   Dmoj\GI12083 Y   Drosophila grimshawi   Dgri\GH15146 Y
Orthologs in non-Drosophila Dipterans (EOG6W0XP8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001759   Anopheles gambiae Malaria mosquito  Agam\AGAP005061   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004888
Orthologs in non-Dipteran Insects (EOG65X6SG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\RpS9   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000944   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19307   Atta cephalotes Leafcutter ant  Acep\ACEP15116   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23360   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20880   Linepithema humile Argentine ant  Lhum\LH13276   Pogonomyrmex barbatus Red harvester ant  Pbar\PB22763   Solenopsis invicta Red fire ant  Sinv\SINV24700   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000783   Bombyx mori Silkmoth  Bmor\RpS9   Pediculus humanus Human body louse  Phum\PHUM492730   Tribolium castaneum Red flour beetle  Tcas\TC006782
Orthologs in non-Insect Arthropods (EOG6Z8WCS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\PB1-F2   Daphnia pulex Water flea  Dpux\COI   Daphnia pulex Water flea  Dpux\COI   Ixodes scapularis Deer tick  Isca\ISCW023083
Orthologs in non-Arthropod Metazoa (EOG6DRP74)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rps-9   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008394gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006605gn   Danio rerio Zebrafish  Drer\rps9   Xenopus tropicalis Western clawed frog  Xtro\rps9   Mus musculus House mouse  Mmus\Rps9   Rattus norvegicus Norway rat  Rnor\Rps9   Rattus norvegicus Norway rat  Rnor\LOC365692   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038658   Rattus norvegicus Norway rat  Rnor\RGD1566136   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000034090   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9   Homo sapiens Human  Hsap\RPS9
Human Orthologs (7)
Gene OMIM HGNC Hsap\RPS9     Hsap\RPS9     Hsap\RPS9     Hsap\RPS9     Hsap\RPS9     Hsap\RPS9     Hsap\RPS9
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12912 Drosophila sechellia Dsec\GM24860 Drosophila erecta Dere\GG14025 Drosophila yakuba Dyak\RpS9 Drosophila ananassae Dana\GF24655 Drosophila pseudoobscura pseudoobscura Dpse\GA28351 Drosophila persimilis Dper\GL17960 Drosophila willistoni Dwil\GK17575 Drosophila virilis Dvir\GJ13353 Drosophila mojavensis Dmoj\GI12083 Drosophila grimshawi Dgri\GH15146
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	18647 w1118; PBac{WH}RpS9f03376 33394 y1 sc* v1; P{TRiP.HMS00271}attP2 27225 y1 w*; P{EP}RpS9G7201/TM3, Sb1 Ser1
Harvard	- PBac{WH}RpS9f03376
VDRC	v100712 P{KK108037}VIE-260B
Genomic Clones ( 1 )
	BACR12K04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 582 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP08778 LD13662 LD32106
Other clones	yak-ad_RpS9 yak-em_RpS9
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04976 AT07930 AT09751 AT28757 AT28984 AT30968 GH01541 GH03001 GH03393 GH03611 GH04255 GH05236 GH06120 GH08180 GH09077 GH09159 GH09272 GH09625 GH11830 GH12658 GH14471 GH14504 GH15419 GH15977 GH17286 GH17320 GH20627 GH22248 GH22258 GH24232 GH25601 GM03414 GM06034 GM08525 GM10402 GM10721 GM14320 GM14943 GM15493 GM15910 GM16451 GM17262 GM17369 GM17809 GM17863 GM18828 GM20458 GM20738 GM20933 GM22743 GM22908 GM23992 GM24463 GM27042 GM27118 GM27548 GM27924 GM28303 GM28343 GM28587 GM30036 GM30153 GM30847 HL02816 LD04988 LD06156 LD06358 LD06692 LD07713 LD12607 LD12618 LD15762 LD16192 LD22419 LD25355 LD25357 LD25606 LD25695 LD27466 LD29373 LD30131 LD30304 LD30483 LD30709 LD33492 LD35167 LD36496 LD37210 LD37450 LD38133 LD39791 LD40636 LD43575 LD44516 LD46195 LD46615 LP01433 LP01992 LP02410 LP03423 LP03786 LP05957 LP07678 LP08605 LP10255 LP11179 LP11651 LP11777 LP12266 LP12516 LP12858 LP13544 LP15602 LP16033 LP17451 LP17859 LP19338 LP21068 LP22058 LP22290 LP22316 RE43613 RE55108 RE71783 RH37328 RH37382 RH38011 RH38044 RH38667 RH38829 RH46845 RH59455 RH59541 RH61020 RH63695 RH74115 SD10845 SD11349 SD11463 SD12187 SD12437 SD12761 SD12886 SD12937 SD12963 SD13309 SD14149 SD14319 SD14568 SD15275 SD15294 SD16366 SD16572 SD16768 SD17730 SD18103 SD18383 SD18786 SD19701 SD20801 SD20903 SD21274 SD21959 SD22075 SD22179 SD22514 SD22587 SD22755 SD23039 SD23267 SD23558 SD23592 SD25223 SD26272 SD26990 SD27189 SD27276 SD27578
Other clones	31172 41768 54374 59600 81019 98318 159501 190914 241053 281379 521949 523030 523844 524012 542651 558025 562250 569064 569493 569676 569891 AT31122 bs85a01 CK01.6B.D3 CK01.55C.D8 CK01.90B.E6 CK01.97D.C6 CK01.101D.D4 Dmel_dig_000796_0657_2585 Dmel_dig_001351_0598_0414 Dmel_dig_001688_0719_0510 Dmel_dig_002986_0588_3634 Dmel_dig_003723_0638_1155 Dmel_dig_004203_0600_3633 Dmel_dig_004296_0627_3459 Dmel_dig_005617_0628_1471 Dmel_dig_006640_0596_1361 Dmel_dig_007086_0702_2819 Dmel_dig_008233_0666_3443 Dmel_dig_008283_0689_3459 Dmel_dig_009174_0606_2522 Dmel_dig_010949_0644_2744 Dmel_dig_011186_0681_1146 Dmel_dig_011982_0604_2202 Dmel_dig_012569_0591_2413 Dmel_dig_013896_0663_1620 Dmel_dig_014173_0709_3360 Dmel_dig_014411_0697_2170 Dmel_dig_014671_0705_1593 Dmel_dig_015682_0580_2799 Dmel_dig_015857_0655_0822 Dmel_dig_017253_0679_2984 Dmel_dig_017409_0593_0991 Dmel_dig_018361_0662_2079 Dmel_dig_018722_0604_1009 Dmel_dig_019504_0697_2675 Dmel_dig_019570_0630_2977 Dmel_dig_020868_0655_2192 Dmel_neb_001391_0658_3629 Dmel_neb_008873_0644_3571 Dmel_neb_009320_0831_3381 Dmel_neb_009880_0693_1514 Dmel_neb_010186_0687_3557 Dmel_neb_010569_0446_0511 Dmel_neb_010645_0581_2371 Dmel_neb_011039_0086_1103 Dmel_neb_011760_0655_3110 Dmel_neb_011930_0440_3219 Dmel_neb_012050_0662_0732 Dmel_neb_012886_0851_2331 Dmel_neb_013774_0876_1406 Dmel_neb_014129_0610_2030 Dmel_neb_014216_0682_2547 Dmel_neb_014503_0640_1330 Dmel_neb_014827_0582_1076 Dmel_neb_015056_0438_0517 Dmel_neb_015378_0391_2144 Dmel_neb_015462_0936_1252 Dmel_neb_015575_0677_2644 Dmel_neb_015594_0571_1418 Dmel_neb_016091_0578_1751 EC13542 EC25439 EC26251 EC28826 EC30802 EC34650 EC36628 EC36934 EC37251 EC40711 EK044848 EK068402 EK075743 EK085846 EK139827 EK154634 EK184344 EK214617 EK262510 EK293143 EK306538 EN00845 EN03254 EN04310 EN04612 EN11035 EN12843 EN14453 EN15011 EN15357 EN15825 EN16701 ESG0115b.B21_A05 FGA004C02 FGB001A04 FGB001E10 FGC017H01 FGC020F03 FGC025A04 FGC025H11 FGC028D02 FGC029C07 FGC032E03 FGH108H07 FGH111H04 FGH115B04 FGH127B05 FGH127F01 FGM206C11 FGM218A10 FGM218C03 FGM229A02 FGM235G06 FGM237D06 FGM303C03 FGM306G08 FGM318E05 GM02558 GM03932 GM06032 GM06993 GM07568 GM08607 GM10482 GM14790 GM15480 GM20150 GM23128 GM23579 GM24341 GM25088 GM26589 GM28664 IP03485 IP04830 IP11082 IP12173 IP12273 IP12373 IP13402 IP15691 IP17249 IP17449 IP17549 LD02172 LD04255 LD07270 LD11482 LD12119 LD25953 LD32475 LP21328 RE01366 RE01831 RE01864 RE02942 RE03047 RE05632 RE05967 RE06180 RE07563 RE08807 RE09028 RE09527 RE09853 RE10260 RE13222 RE13868 RE15246 RE15615 RE17972 RE18009 RE18463 RE20171 RE22693 RE23822 RE25389 RE27176 RE27860 RE28115 RE29668 RE30102 RE30528 RE31079 RE35239 RE35584 RE36878 RE36955 RE39256 RE39463 RE39501 RE41057 RE41581 RE42301 RE42442 RE45181 RE47194 RE49948 RE52485 RE52961 RE53222 RE53251 RE54568 RE54905 RE55004 RE55385 RE57418 RE58139 RE60684 RE60962 RE63109 RE66340 RE66531 RE67921 RE71316 RE72180 RE73680 RH02070 RH02226 RH02622 RH03194 RH06015 RH06234 RH06576 RH06818 RH08246 RH08253 RH08271 RH08295 RH08527 RH08663 RH08778 RH10267 RH10353 RH10755 RH11840 RH12727 RH12994 RH13048 RH14058 RH14441 RH17494 RH19063 RH19093 RH19849 RH20170 RH20910 RH22809 RH23369 RH23626 RH23819 RH23830 RH23961 RH25133 RH25863 RH25894 RH26090 RH26925 RH26928 RH26944 RH27266 RH27353 RH27970 RH29866 RH30751 RH30795 RH30895 RH32240 RH32602 RH32681 RH32737 RH32760 RH32985 RH33358 RH33807 RH33988 RH34153 RH35404 RH35628 RH35736 RH36111 RH36333 RH36737 RH37485 RH37665 RH38156 RH38919 RH38950 RH39326 RH39590 RH42881 RH43767 RH44029 RH46009 RH46137 RH49586 RH49687 RH49767 RH50512 RH51128 RH51818 RH51874 RH52282 RH52559 RH53864 RH54077 RH54091 RH54468 RH55029 RH56263 RH56479 RH56558 RH56660 RH56771 RH57630 RH57776 RH58279 RH58554 RH58576 RH58783 RH58917 RH61034 RH61131 RH61672 RH62015 RH62360 RH62925 RH63020 RH63426 RH63550 RH63557 RH63685 RH64106 RH66004 RH66602 RH66672 RH68205 RH68242 RH68739 RH69008 RH69244 RH69552 RH70516 RH72309 RH72968 RH73551 RH73659 RH74249 RH74404 RH74578 RH74689 RH74741 RP004118060 RP004137039 RP004152741 RP004159356 RP004173084 RP004198140 RP004216450 RP004218928 RP004227432 RP004229869 RP004235445 RP004241346 RP004254803 RP004257215 RP004388547 RP004404617 RP004424070 RP004459205 RP004532649 RP004533123 RP004550604 SD15523 SD18329 SD18772 SD22470 UT01303
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010408 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39108
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	The genetically defined "M(3)67C" locus (characterized by previous aneuploidy analyses) likely comprises two separable, closely linked Minute genes ("RpS9" and "RpS17"). (Marygold et al., 2007)
Other Comments
	Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene. (Hansen et al., 2009) RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Minute gene. (Marygold et al., 2007) A deletion removing both RpS9 and RpS17 but no other cytoplasmic ribosomal protein-encoding genes shows Minute phenotypes. (Marygold et al., 2007) Molecularly-defined mutations in RpS9 result in Minute phenotypes. (Marygold et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) <up>FlyBase curator comment: the ribosomal gene cloned in this paper was originally called "RpL11" in FlyBase, based on its homology to the S.cerevisiae "ys11" gene. It has subsequently been changed to "RpS9" in FlyBase, as the name of the S.cerevisiae gene changed to "ys9"</up>. (Zhang and Bownes, 1993) RpS9 encodes a ribosomal protein that is abundant in the ovary suggesting that the mRNA is maternally stored for utilisation in embryogenesis to enable the rapid production of ribosomal proteins and assembly of ribozymes. (Zhang and Bownes, 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079280 NM_168350 NM_168351 RefSeq (Proteins) • NP_524004 NP_729506 NP_729507 DDBJ / EMBL / GenBank • AA978620 AAF50249 AAF50250 AAL28944 AAN11946 AW943120 AY061396 CAB41492 X69677 Entrez Gene - A searchable database of RefSeq genes. • 39108 UniProtKB/Swiss-Prot • P55935 UniProtKB/TrEMBL • Q95RG1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S4, conserved site (IPR018079) Ribosomal protein S4/S9, N-terminal (IPR001912) RNA-binding S4 domain (IPR002942) Ribosomal protein S4/S9, eukaryotic/archaeal (IPR005710) Ribosomal protein S4/S9 (IPR022801) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD32106
Linkouts
	BioGRID - A database of protein and genetic interactions • 64500 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0010408 DroID - A comprehensive database of gene and protein interactions. • FBgn0010408 DRSC - Results from RNAi screens. • FBgn0010408 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010408 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3395-RB;CG3395-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010408 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39108 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39108 modMine - Data generated by the modENCODE project. • FBgn0010408
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG3395 (Huang et al., 2005, Goshima et al., 2007, Marygold et al., 2007, Keleman et al., 2009.8.5, Ni et al., 2010.12.1, Cammarato et al., 2011) RpL11   RpS9 (Wang et al., 2004, Fischer et al., 2012, Goshima et al., 2007, Zhang et al., 2007, Kallappagoudar et al., 2010, Marygold et al., 2007, Nie et al., 2009, Hansen et al., 2009, Zhou et al., 2008, Mourikis et al., 2010, Cook et al., 2012, Plocik and Guthrie, 2012, Killip and Grewal, 2012) Rp S9 (Alonso and Santaren, 2006) S9 (Carpenter et al., 2009) unnamed (Zhang and Bownes, 1993)
Name Synonym	Ribosomal protein S9 (Manh et al., 2005, Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 49 )
Generate a list of	All references relating to this gene ( 49 )
List References by type	Research paper  ( 21 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 12 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 5 )
	Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066] Fischer et al., 2012, Proc. Biol. Sci. 279(1738): 2636--2644 Conserved properties of Drosophila and human spermatozoal mRNA repertoires. [FBrf0218415] Killip and Grewal, 2012, Dev. Biol. 371(2): 191--202 DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. [FBrf0219592] Plocik and Guthrie, 2012, PLoS Genet. 8(3): e1002620 Diverse Forms of RPS9 Splicing Are Part of an Evolving Autoregulatory Circuit. [FBrf0218008] Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Show all research papers ...