Gene Dmel\RpS18

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General Information

Symbol

Dmel\RpS18

Species

D. melanogaster

Name

Ribosomal protein S18

Annotation symbol

CG8900

Feature type

protein_coding_gene

FlyBase ID

FBgn0010411

Gene Model Status

Current

Stock availability

1 publicly available

Also Known As

S18

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

56F11-56F11

Sequence location

2R:16,151,484..16,152,353 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene Ribosomal protein S18 is referred to in FlyBase by the symbol Dmel\RpS18 (CG8900, FBgn0010411). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; mitotic spindle organization. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ribosomal protein S13; Ribosomal protein S13, conserved site; Ribosomal protein S13-like, H2TH. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1624983_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of RpS18. Gene sequence location is 2R:16151477..16152353.

User Contributed Data

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Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

Controlled Vocabulary Terms

ribosome biogenesis

cytosol

small ribosomal subunit

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

56F11-56F11

Limits computationally determined from genome sequence between P{lacW}Ate1^k10809 and P{EP}CG10444^EP951

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

56F-56F

(Garwood, 1993)

56F-56F

(determined by in situ hybridisation)

(Garwood and Lepesant, 1994)

56F-56F

(Axton et al., 1994)

Experimentally Determined Recombination Data

Location

(Axton et al., 1994)

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\RpS18 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.39

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.51

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

RpS18-RA

FBtr0086274

NM_057616

583

152

RpS18-RB

FBtr0086273

NM_166383

606

152

Additional Transcript Data & Comments

Reported size (kB)

0.7 (northern blot)

(Garwood and Lepesant, 1994)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

RpS18-PA

FBpp0085586

17.6

152

11.17

NP_476964

AAF57491

RpS18-PB

FBpp0085585

17.6

152

11.17

NP_725943

AAM68401

Additional Polypeptide Data & Comments

Reported size (kDa)

152 (aa); 18 (kD predicted)

(Garwood and Lepesant, 1994)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Ribosomal protein S13, conserved site (IPR018269)

Ribosomal protein S13 (IPR001892)

Ribosomal protein S13-like, H2TH (IPR010979)

30s ribosomal protein S13, C-terminal (IPR027437)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

P41094

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3