FlyBase Gene Report: Dmel\TpnC73F

General Information

Symbol

Dmel\TpnC73F

Species

D. melanogaster

Name

Troponin C at 73F

Annotation Symbol

CG7930

Feature Type

protein_coding_gene

FlyBase ID

FBgn0010424

Gene Model Status

Current

Stock Availability

5 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

TnC, DmTpnCIa, Tnc2, TnC73F

Key Links

Genomic Location

Cytogenetic map

73E5-73E5

Sequence location

3L:17,046,063..17,048,390 [+]

Recombination map

3-45

RefSeq locus

NT_037436 REGION:17046063..17048390

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (3 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables calcium ion binding

inferred from electronic annotation with InterPro:IPR002048

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000549682

(GO Reference Genome Project, 2011-)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in centrosome

inferred from biological aspect of ancestor with PANTHER:PTN008588806

(GO Reference Genome Project, 2011-)

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN008588804

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

TROPONIN C ISOFORMS

Protein Family (UniProt)

Belongs to the troponin C family. (P47949)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

TROPONIN C ISOFORMS -: The troponin complex associates with tropomyosin (Tm1) and controls the contraction of the striated muscle in response to changes in intracellular calcium concentration. Troponin C (TpnC) is the calcium-binding subunit of the troponin complex and, in insects, is encoded by multiple genes. (Adapted from FBrf0184125.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\TpnC73F for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry P47949)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.41

Gene model reviewed during 5.46

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

TpnC73F-RA

FBtr0089585

NM_079398

962

155

TpnC73F-RC

FBtr0345120

NM_001300162

1059

155

Additional Transcript Data and Comments

Reported size (kB)

0.9 (northern blot)

(Fyrberg et al., 1994)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

TpnC73F-PA

FBpp0088546

17.7

155

3.81

FBpp0311345

17.7

155

3.81

P47949

NP_001287091

AHN58116

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

155 aa isoforms: TpnC73F-PA, TpnC73F-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

155 (aa)

(Fyrberg et al., 1994)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TpnC73F using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.27

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

somatic muscle primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

larval muscle system

(Fisher et al., 2012)

larval somatic muscle cell

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 17

organism

(Fyrberg et al., 1994)

larval stage

(Fyrberg et al., 1994)

pupal stage

(Fyrberg et al., 1994)

pcr

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

organism

(Qiu et al., 2003)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

oogenesis

border follicle cell

(Borghese et al., 2006)

Additional Descriptive Data

TpnC73F is enriched in border follicle cells relative to follicle cells.

(Borghese et al., 2006)

Expression of TpnC73F was detected in 4 h embryos and persisted throughout development and into adult stages. However, expression was lower in the adult.

(Qiu et al., 2003)

TpnC73F transcripts are detected at nearly equal levels in late embryos, larvae, and pupae.

(Fyrberg et al., 1994)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\TpnC73F in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\TpnC73F

View exonic expression by tissue for Dmel\TpnC73F

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010424

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

39916/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0010424

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0010424

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0010424

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7930

Flygut - An atlas of the Drosophila adult midgut

FBgn0010424

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\TpnC73F

Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of TpnC73F

Transgenic constructs containing regulatory region of TpnC73F

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 4 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Mef2.PR

lethal - all die during embryonic stage, with Scer\GAL4^Mef2.PR

TpnC73F^GD12497

lethal - all die during P-stage, with Scer\GAL4^Mef2.PR

TpnC73F^GD10670

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

Phenotype manifest in

Allele

sarcomere, with Scer\GAL4^Mef2.PR

TpnC73F^GD12497

Z disc, with Scer\GAL4^Mef2.PR

TpnC73F^GD12497

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (41)

Hsap\CALML6

3 of 14

Yes

Hsap\CABP4

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Yes

Hsap\AIF1L

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Hsap\LOC118142757

1 of 14

Hsap\NCALD

1 of 14

Hsap\NCS1

1 of 14

Hsap\PHF24

1 of 14

Yes

Hsap\PPP3R1

1 of 14

Hsap\PPP3R2

1 of 14

Hsap\SPATA21

1 of 14

Yes

Hsap\TESC

1 of 14

Hsap\TNNC1

1 of 14

Hsap\TNNC2

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (19)

Rnor\Calm1

2 of 14

Yes

Rnor\Calm2

2 of 14

Yes

Rnor\Calm3

2 of 14

Yes

Rnor\Calml3

2 of 14

Yes

Rnor\Aif1l

1 of 14

Yes

Rnor\Aif1

1 of 14

Yes

Rnor\Cabp1

1 of 14

Yes

Rnor\Cabp4

1 of 14

Rnor\Calml4

1 of 14

Rnor\Caps2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Efhd1

1 of 14

Rnor\Efhd2

1 of 14

Rnor\Phf24

1 of 14

Yes

Rnor\Spata21

1 of 14

Yes

Rnor\Tnnc2

1 of 14

Mus musculus (laboratory mouse) (21)

Mmus\Calm1

2 of 14

Yes

Mmus\Calm2

2 of 14

Yes

Mmus\Calm3

2 of 14

Yes

Mmus\Calm4

2 of 14

Yes

Mmus\Calml3

2 of 14

Yes

Mmus\Aif1l

1 of 14

Yes

Mmus\Aif1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Efhd1

1 of 14

Mmus\Efhd2

1 of 14

Mmus\Phf24

1 of 14

Yes

Mmus\Spata21

1 of 14

Yes

Mmus\Tnnc2

1 of 14

Xenopus tropicalis (Western clawed frog) (18)

Xtro\cabp4

1 of 13

Yes

Xtro\calml4

1 of 13

Yes

Xtro\cetn3

1 of 13

Yes

Xtro\chp1

1 of 13

Yes

Xtro\cib1

1 of 13

Yes

Xtro\cib2

1 of 13

Yes

Xtro\dnaaf10

1 of 13

Yes

Xtro\efhd1

1 of 13

Yes

Xtro\efhd2

1 of 13

Yes

Xtro\guca1a

1 of 13

Yes

Xtro\hpcal1

1 of 13

Yes

Xtro\ncald

1 of 13

Yes

Xtro\ncs1

1 of 13

Yes

Xtro\neil2

1 of 13

Yes

Xtro\ocm4.6

1 of 13

Yes

Xtro\tesc

1 of 13

Yes

Xtro\tnnc1

1 of 13

Yes

Xtro\tnnc2

1 of 13

Yes

Danio rerio (Zebrafish) (23)

Drer\calm1a

2 of 14

Yes

Drer\calm1b

2 of 14

Yes

Drer\calm2a

2 of 14

Yes

Drer\calm2b

2 of 14

Yes

Drer\calm3a

2 of 14

Yes

Drer\calm3b

2 of 14

Yes

Drer\cetn3

2 of 14

Yes

Drer\aif1l

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\si:cabz01076231.1

1 of 14

Drer\tnnc1a

1 of 14

Drer\tnnc1b

1 of 14

Drer\tnnc2.1

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (20)

Cele\tnc-2

13 of 14

Yes

Cele\pat-10

4 of 14

Yes

Cele\cal-3

2 of 14

Cele\K03A1.4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Cele\ncs-1

1 of 14

Cele\ncs-2

1 of 14

Cele\pbo-1

1 of 14

Anopheles gambiae (African malaria mosquito) (18)

Agam\AgaP_AGAP007339

12 of 12

Yes

5 of 12

4 of 12

4 of 12

4 of 12

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (49)

Atha\CML37

3 of 13

Yes

Atha\AT1G18530

2 of 13

Yes

Atha\AT1G24620

2 of 13

Yes

Atha\AT1G32250

2 of 13

Yes

Atha\AT1G76640

2 of 13

Yes

Atha\AT3G01830

2 of 13

Yes

Atha\AT3G03000

2 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Yes

Atha\CML41

2 of 13

Yes

Atha\CML42

2 of 13

Yes

Atha\CML43

2 of 13

Yes

Atha\AGD11

1 of 13

Yes

Atha\AT1G05990

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT3G59440

1 of 13

Yes

Atha\AT4G03290

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\MSS3

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\CMD1

2 of 13

Yes

Scer\CNB1

1 of 13

Scer\FRQ1

1 of 13

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\cam1

2 of 12

Yes

Spom\cam2

1 of 12

Spom\cdc31

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:TpnC73F. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (32)

12 of 13

9 of 13

4 of 13

4 of 13

3 of 13

2 of 13

2 of 13

Cam

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

elm

1 of 13

Frq1

1 of 13

Frq2

1 of 13

Nca

1 of 13

Nox

1 of 13

Swip-1

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CALML6; calmodulin like 6

3 of 14

610171

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

65208

DroID - A comprehensive database of gene and protein interactions.

FBgn0010424

MIST (protein-protein) - An integrated Molecular Interaction Database

39916

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-45

Cytogenetic map

73E5-73E5

Sequence location

3L:17,046,063..17,048,390 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

73E5-73E5

Limits computationally determined from genome sequence between P{PZ}Baldspot⁰²²⁸¹ and P{PZ}blot⁰¹⁶⁵⁸

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

73F-73F

(Fyrberg, 1993.11.8)

73F-73F

(determined by in situ hybridisation)

(Fyrberg et al., 1994)

Experimentally Determined Recombination Data

Location

3-45

(FlyBase, 2016)

3-39.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (5)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

80875

y¹, v¹; P{TKO.GS04779}attP40

24549

w¹¹¹⁸; Mi{ET1}TpnC73F^MB03946/TM6C, Sb¹

NIG-Fly

7930R-1

P{NIG.7930R}1

VDRC

v23076

w¹¹¹⁸; P{GD12497}v23076

v34272

w¹¹¹⁸; P{GD10670}v34272

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (100)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LP10264

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0010424

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0010424

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

BB14/7.1

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Gene expression is increased in response to the presence of either one or two copies of Scer\GAL4^hs.PB.

(Liu and Lehmann, 2008)

Isolation and characterisation of Troponin C like gene TpnC73F.

(Fyrberg et al., 1994)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

CG7930

(Çiçek et al., 2016, Cammarato et al., 2011, Goldstein and Gunawardena, 2000)

DmTnC3

(Qiu et al., 2003)

DmTpnC73F

(Herranz et al., 2004)

DmTpnCIa

(Herranz et al., 2005, Herranz et al., 2004)

TNC

(Diaz-Castillo and Golic, 2004)

TNC73F

(Diaz-Castillo and Golic, 2007)

TnC

(Wishard et al., 2023, Rui et al., 2010, Nongthomba et al., 2004, Ruiz et al., 2002)

TnC73F

(Fyrberg, 1993.11.8)

Tnc2

(Kollmar, 2006, Kollmar and Odronitz, 2006)

TpnC Ia

(Herranz et al., 2004)

TpnC73F

(Trujillo et al., 2024, Brener et al., 2023, Zhang et al., 2023, Adashev et al., 2022, DeAngelis et al., 2021, Wang et al., 2018, Transgenic RNAi Project members, 2017-, Johnson et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Schnorrer et al., 2010, Liu and Lehmann, 2008, Baker et al., 2007, Dietzl et al., 2007, Junion et al., 2007, Montana and Littleton, 2006)

TpnCIa

(Herranz et al., 2005)

tpnC73F

(Hornbruch-Freitag et al., 2011)

Name Synonyms

Troponin C at 73F

(Johnson et al., 2013, Cammarato et al., 2011)

TroponinC73F

(Hornbruch-Freitag et al., 2011)

troponin C

(OOta and Saitou, 1999)

troponin C73F

(Borghese et al., 2006)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 44 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

39916

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

P47949

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

P47949

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

P47949

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010424

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

39916/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0010424

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0010424

FlyMine - An integrated database for Drosophila genomics

FBgn0010424

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG7930

MARRVEL_MODEL - MARRVEL (model organism gene)

39916

Linkouts

BioGRID - A database of protein and genetic interactions.

65208

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0010424

DroID - A comprehensive database of gene and protein interactions.

FBgn0010424

DRSC - Results frm RNAi screens

FBgn0010424

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

BB14/7.1

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0010424

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0010424

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7930

Flygut - An atlas of the Drosophila adult midgut

FBgn0010424

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0010424

MIST (protein-protein) - An integrated Molecular Interaction Database

39916

References (64)

The following external sites may use different assemblies or annotations than FlyBase.

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