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Gene Dmel\emp

General Information
Symbol	Dmel\emp	Species	D. melanogaster
Name	epithelial membrane protein	Annotation symbol	CG2727
Feature type	protein_coding_gene	FlyBase ID	FBgn0010435
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60E11-60E11	Sequence location	2R:20,863,979..20,872,321 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: scavenger receptor activity. There is experimental evidence that it is involved in the biological process: autophagic cell death; salivary gland cell autophagic cell death. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Adhesion molecule CD36; CD36 antigen; Lysosome membrane protein II. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, larval trachea, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae. Comments on Affy2 ProbeSet: ProbeSet 1636991_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of emp. Gene sequence location is 2R:20863979..20872321.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60E11-60E11   Limits computationally determined from genome sequence between P{EP}CG2790EP412&P{EP}CG3776EP835 and P{EP}zipEP856&P{PZ}l(2)1048103263
Experimentally Determined Cytological Location
Cytogenetic map Notes References 60E-60E     (Hart, 1993.6.11)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\emp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) emp-RA FBtr0072402  NM_079135   2280   520 emp-RB FBtr0072401  NM_166702   2252   551 emp-RC FBtr0072400  NM_166703   2526   520
Additional Transcript Data & Comments
Reported size (kB)	2.5 (northern blot) (Hart and Wilcox, 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein emp-PA   FBpp0072309   58.7   520   6.38     NP_523859   AAF47309 emp-PB   FBpp0072308   62.0   551   6.20     NP_726504   AAM70803 emp-PC   FBpp0072307   58.7   520   6.38     NP_726505   AAM70804
Additional Polypeptide Data & Comments
Reported size (kDa)	519 (aa) (Hart and Wilcox, 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • CD36 antigen (IPR002159) Adhesion molecule CD36 (IPR005428) Lysosome membrane protein II (IPR005429)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA698298   AA802851   AA949562   AE013599 AAF47309   AE013599 AAM70803   AE013599 AAM70804   AI062181   AI062346   AI064498   AI106606   AI107534   AI108779   AI109888   AI133879   AI257919   AI258467   AI260943   AI292809   AI296015   AI387254   AI387423   AI388668   AI388937   AI403187   AI405222   AI514099   AI514226   AI518414   AI518872   AI945580   AI947085   AW940239   AY070494 AAL47965   BF486610   BF487192   BF487432   BF488708   BF489762   BF491294   BF500437   BF503327   BF503566   BF505906   BG638758   BI163964   BI166005   BI167076   BI167693   BI169361   BI213015   BI232534   BI239867   BI242636   BI242666   BI354325   BI372056   BI584190   BI615444   BI617086   BI621741   BP542922   BT001535 AAN71290   CA803842   CA803955   CA803965   CA804032   CA804474   CA806381   CA806548   CA807384   CO188658   CO188903   CO191579   CO271539   CO281475   CO289732   CO293050   CO294977   CO303820   CO303872   CO307880   CO309248   CO314353   CO315414   CO326931   CO330036   CO340124   CZ481907   CZ481908   CZ484610   CZ489795   DN154139   EC063708   EC064930   EC077565   EC202374   EC203686   EC207766   EC225265   EC226723   EC229790   EC232117   EC233929   EC234837   EC238344   EC245320   EC250759   EC257019   EL884300   EV577184   EV586148   EV588262   EV588548   GH945910   GH953832   GH954979   GH955096   GH956561   GH957588   GH977816   GH979825   GH983864   X73332 CAA51759
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KVF1 Q9W0X0 Q8IGY0 Q8SZV3 Q24336
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 17   ectoderm   (Hart and Wilcox, 1993) Comment:reference states >=6 hr AEL embryonic/larval foregut | restricted   (Hart and Wilcox, 1993) Comment:reference states >=6 hr AEL embryonic/larval hindgut | restricted   (Hart and Wilcox, 1993) Comment:reference states >=6 hr AEL epidermis   (Hart and Wilcox, 1993) Comment:reference states >=6 hr AEL embryonic stage 13 -- 16   embryonic dorsal epidermis   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic esophagus   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic hypopharynx   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic small intestine   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 17     (Hart and Wilcox, 1993) Comment:reference states >=6 hr AEL embryonic stage 13   embryonic/larval tracheal system   (Hart and Wilcox, 1993) third instar larval stage   wing disc | restricted   (Hart and Wilcox, 1993) peripodial epithelium of wing disc   (Hart and Wilcox, 1993) imaginal disc   (Hart and Wilcox, 1993) pupal stage | early   imaginal disc   (Hart and Wilcox, 1993) wing disc | restricted   (Hart and Wilcox, 1993) peripodial epithelium of wing disc   (Hart and Wilcox, 1993)
Additional Descriptive Data
	emp transcript first appears during 6-8 hours of embryogenesis, and continues to be detected throughout development. During embryogenesis, expression is restricted to the ectoderm, and especially to various epithelial tissues, including embryonic epidermis and the foregut and hindgut epithelia. After germ band retraction, additional expression is detected in subepidermal tissue that may correspond to the tracheal tree. Expression in imaginal disc epithelial cells is detected in third instar larval through mid-pupal stages. In the third instar larval wing disc, expression is seen in columnar epithelial cells, but not in the adepithelial cells. Expression is also detected in the peripodial membrane. (Hart and Wilcox, 1993)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
plasma membrane inferred from direct assay (Khanna et al., 2010)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, larval trachea, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea    2386.65 Larval Carcass    585.55 Adult Head    1342.2 Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop    4835.7 Adult Midgut    229.5 Adult Hindgut    2254.6 Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis    1415.3 Adult Male Accessory Gland    96 Adult Carcass    1536.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut  532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea  (2386.65) Larval Carcass  (585.55) Adult Head  (1342.2) Adult Eye  (588.85) Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop  (4835.7) Adult Midgut    229.5 Adult Hindgut  (2254.6) Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis  (1415.3) Adult Male Accessory Gland    96 Adult Carcass  (1536.1) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea  (2386.65) Larval Carcass    585.55 Adult Head  (1342.2) Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop  (4835.7) Adult Midgut    229.5 Adult Hindgut  (2254.6) Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis  (1415.3) Adult Male Accessory Gland    96 Adult Carcass  (1536.1) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea    2386.65 Larval Carcass    585.55 Adult Head    1342.2 Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop    4835.7 Adult Midgut    229.5 Adult Hindgut    2254.6 Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis    1415.3 Adult Male Accessory Gland    96 Adult Carcass    1536.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea    2386.65 Larval Carcass    585.55 Adult Head    1342.2 Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop    4835.7 Adult Midgut    229.5 Adult Hindgut    2254.6 Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis    1415.3 Adult Male Accessory Gland    96 Adult Carcass    1536.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut  532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea  (2386.65) Larval Carcass  585.55 Adult Head  (1342.2) Adult Eye  588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop  (4835.7) Adult Midgut    229.5 Adult Hindgut  (2254.6) Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis  (1415.3) Adult Male Accessory Gland    96 Adult Carcass  (1536.1) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea  (2386.65) Larval Carcass    585.55 Adult Head  1342.2 Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop  (4835.7) Adult Midgut    229.5 Adult Hindgut  (2254.6) Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis  1415.3 Adult Male Accessory Gland    96 Adult Carcass  1536.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    68.075 Larval Midgut    247.8 Larval Hindgut    532.8 Larval Malpighian Tubules    234.3 Larval Fat Body    285.7 Larval Salivary Gland    173.7 Larval Trachea    2386.65 Larval Carcass    585.55 Adult Head    1342.2 Adult Eye    588.85 Adult Brain    43.6 Adult Thoracic-Abdominal Ganglion    40.4 Adult Crop    4835.7 Adult Midgut    229.5 Adult Hindgut    2254.6 Adult Malpighian Tubules    188.6 Adult Fat Body    200.2 Adult Salivary Gland    202.9 Adult Heart    166.3 Adult VirginFemale Spermatheca    115.8 Adult InseminatedFemale Spermatheca    131.9 Adult Ovary    96.2 Adult Testis    1415.3 Adult Male Accessory Gland    96 Adult Carcass    1536.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1342.2   NA  Eye    588.85   NA  Brain    43.6   68.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    40.4   NA  Crop    4835.7   247.8  Midgut    229.5   532.8  Hindgut    2254.6   234.3  Malpighian Tubules    188.6   285.7  Fat Body    200.2   173.7  Salivary Gland    202.9   NA  Heart    166.3   2386.65  Trachea    NA   NA  VirginFemale Spermatheca    115.8   NA  InseminatedFemale Spermatheca    131.9   NA  Ovary    96.2   NA  Testis    1415.3   NA  Male Accessory Gland    96   585.55  Carcass    1536.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female    104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male    124 head, mated 4-day male    142 head, mated 20-day male    194 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult    105 carcass, 20-day adult    106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    161 accessory gland, mated 4-day male    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (74) central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female  (91) head, virgin 4-day female  (77) head, virgin 20-day female  (104) head, mated 1-day female  (72) head, mated 4-day female  (82) head, mated 20-day female  (84) head, mated 1-day male  (124) head, mated 4-day male  (142) head, mated 20-day male  (194) salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  (43) digestive system, larvae L3 wandering  (37) digestive system, 1-day adult  (54) digestive system, 4-day adult  (56) digestive system, 20-day adult  (52) fat body, larvae L3 wandering    11 fat body, white prepupae  (38) fat body, pupae P8  (48) carcass, larvae L3 wandering  (63) carcass, 1-day adult  (100) carcass, 4-day adult  (105) carcass, 20-day adult  (106) ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male  (161) accessory gland, mated 4-day male  (31) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female  104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male  (124) head, mated 4-day male  (142) head, mated 20-day male  (194) salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult  105 carcass, 20-day adult  106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male  (161) accessory gland, mated 4-day male    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female    104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male    124 head, mated 4-day male    142 head, mated 20-day male    194 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult    105 carcass, 20-day adult    106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    161 accessory gland, mated 4-day male    31 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female    104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male    124 head, mated 4-day male    142 head, mated 20-day male    194 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult    105 carcass, 20-day adult    106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    161 accessory gland, mated 4-day male    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (74) central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female  (91) head, virgin 4-day female  (77) head, virgin 20-day female  (104) head, mated 1-day female  (72) head, mated 4-day female  (82) head, mated 20-day female  (84) head, mated 1-day male  (124) head, mated 4-day male  (142) head, mated 20-day male  (194) salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  (43) digestive system, larvae L3 wandering  (37) digestive system, 1-day adult  (54) digestive system, 4-day adult  (56) digestive system, 20-day adult  (52) fat body, larvae L3 wandering    11 fat body, white prepupae  (38) fat body, pupae P8  (48) carcass, larvae L3 wandering  (63) carcass, 1-day adult  (100) carcass, 4-day adult  (105) carcass, 20-day adult  (106) ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male  (161) accessory gland, mated 4-day male  31 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female  104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male  124 head, mated 4-day male  142 head, mated 20-day male  (194) salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult  105 carcass, 20-day adult  106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male  (161) accessory gland, mated 4-day male    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    74 central nervous system, larvae L3    10 central nervous system, pupae P8    10 head, virgin 1-day female    91 head, virgin 4-day female    77 head, virgin 20-day female    104 head, mated 1-day female    72 head, mated 4-day female    82 head, mated 20-day female    84 head, mated 1-day male    124 head, mated 4-day male    142 head, mated 20-day male    194 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    43 digestive system, larvae L3 wandering    37 digestive system, 1-day adult    54 digestive system, 4-day adult    56 digestive system, 20-day adult    52 fat body, larvae L3 wandering    11 fat body, white prepupae    38 fat body, pupae P8    48 carcass, larvae L3 wandering    63 carcass, 1-day adult    100 carcass, 4-day adult    105 carcass, 20-day adult    106 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    161 accessory gland, mated 4-day male    31 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr    105 embryo 16-18hr    167 embryo 18-20hr    130 embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr    220 white prepupae 24hr    92 pupae 2d postWPP    127 pupae 3d postWPP    118 pupae 4d postWPP    165 adult male 01day    149 adult male 05day    159 adult male 30day    147 adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr  (41) embryo 14-16hr  (105) embryo 16-18hr  (167) embryo 18-20hr  (130) embryo 20-22hr  (38) embryo 22-24hr  (43) larva L1  26 larva L2  (48) larva L3 12hr old  (56) larva L3 puffstage 1-2  (31) larva L3 puffstage 3-6  (41) larva L3 puffstage 7-9  (49) white prepupae new  (56) white prepupae 12hr  (220) white prepupae 24hr  (92) pupae 2d postWPP  (127) pupae 3d postWPP  (118) pupae 4d postWPP  (165) adult male 01day  (149) adult male 05day  (159) adult male 30day  (147) adult female 01day  (59) adult female 05day  (34) adult female 30day  (28) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr  105 embryo 16-18hr  (167) embryo 18-20hr  (130) embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr  (220) white prepupae 24hr    92 pupae 2d postWPP  (127) pupae 3d postWPP  (118) pupae 4d postWPP  (165) adult male 01day  (149) adult male 05day  (159) adult male 30day  (147) adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr    105 embryo 16-18hr    167 embryo 18-20hr    130 embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr    220 white prepupae 24hr    92 pupae 2d postWPP    127 pupae 3d postWPP    118 pupae 4d postWPP    165 adult male 01day    149 adult male 05day    159 adult male 30day    147 adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr    105 embryo 16-18hr    167 embryo 18-20hr    130 embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr    220 white prepupae 24hr    92 pupae 2d postWPP    127 pupae 3d postWPP    118 pupae 4d postWPP    165 adult male 01day    149 adult male 05day    159 adult male 30day    147 adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr  (41) embryo 14-16hr  (105) embryo 16-18hr  (167) embryo 18-20hr  (130) embryo 20-22hr  (38) embryo 22-24hr  (43) larva L1  26 larva L2  (48) larva L3 12hr old  (56) larva L3 puffstage 1-2  31 larva L3 puffstage 3-6  (41) larva L3 puffstage 7-9  (49) white prepupae new  (56) white prepupae 12hr  (220) white prepupae 24hr  (92) pupae 2d postWPP  (127) pupae 3d postWPP  (118) pupae 4d postWPP  (165) adult male 01day  (149) adult male 05day  (159) adult male 30day  (147) adult female 01day  (59) adult female 05day  (34) adult female 30day  28 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr  105 embryo 16-18hr  (167) embryo 18-20hr  130 embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr  (220) white prepupae 24hr    92 pupae 2d postWPP  127 pupae 3d postWPP  118 pupae 4d postWPP  (165) adult male 01day  (149) adult male 05day  (159) adult male 30day  (147) adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    3 embryo 08-10hr    7 embryo 10-12hr    25 embryo 12-14hr    41 embryo 14-16hr    105 embryo 16-18hr    167 embryo 18-20hr    130 embryo 20-22hr    38 embryo 22-24hr    43 larva L1    26 larva L2    48 larva L3 12hr old    56 larva L3 puffstage 1-2    31 larva L3 puffstage 3-6    41 larva L3 puffstage 7-9    49 white prepupae new    56 white prepupae 12hr    220 white prepupae 24hr    92 pupae 2d postWPP    127 pupae 3d postWPP    118 pupae 4d postWPP    165 adult male 01day    149 adult male 05day    159 adult male 30day    147 adult female 01day    59 adult female 05day    34 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    0 embryonic S1    0 embryonic S3    1 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    14 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3  (27) Cadmium 50 mM 12 hrs, larvae L3  (31) Cadmium 50 mM 48 hrs, 4-day adult  (29) Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult  (59) Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3  (31) Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (33) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (29) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (58) Paraquat 10 mM 48 hrs, 4-day adult  (76) Rotenone 2 μg 12 hrs, larvae L3  26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3  27 Cadmium 50 mM 12 hrs, larvae L3  31 Cadmium 50 mM 48 hrs, 4-day adult  29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult  (59) Ethanol 2.5% 3 hrs, larvae L3  (36) Ethanol 5% 3 hrs, larvae L3  31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (33) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (58) Paraquat 10 mM 48 hrs, 4-day adult  (76) Rotenone 2 μg 12 hrs, larvae L3  26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    27 Cadmium 50 mM 12 hrs, larvae L3    31 Cadmium 50 mM 48 hrs, 4-day adult    29 Cadmium 100 mM 48 hrs, 4-day adult    25 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    25 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    59 Ethanol 2.5% 3 hrs, larvae L3    36 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    24 Caffeine 1.5 mg/ml 4 hrs, larvae L3    33 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    29 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    58 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    26 Rotenone 8 μg 12 hrs, larvae L3    25 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • GH06663 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010435 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2727-RC FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for emp Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 empGD3569 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of emp Class Mutagen Stocks Known lesion empe04154 piggyBac transposase 2 -- empf02107 piggyBac transposase 1 -- empf07039 piggyBac transposase 1 -- empMB02756 1 -- empSH2037 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of emp Class Mutagen Stocks Known lesion empGD3569 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes empHMS02195 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes empNIG.2727R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3569} NA P{NIG.2727R} NA P{TRiP.HMS02195} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}empe04154 NA PBac{WH}empf02107 NA PBac{WH}empf07039 NA insertion of enhancer trap P{lacW}empSH2037 No insertion of enhancer trap binary system Mi{ET1}empMB02756 No
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
autophagic cell death inferred from expression pattern (Gorski et al., 2003) salivary gland cell autophagic cell death inferred from expression pattern (Gorski et al., 2003)
Cellular Component
CV term Evidence References
plasma membrane inferred from direct assay (Khanna et al., 2010)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
scavenger receptor activity inferred from sequence or structural similarity with EMBL:U37799 (FlyBase, 1992-) non-traceable author statement (Lemaitre, 2000.12.20)
Biological Process
CV term Evidence References
cell adhesion inferred from electronic annotation with InterPro:IPR002159, InterPro:IPR005428 (FlyBase Curators et al., 2004-) defense response non-traceable author statement (Lemaitre, 2000.12.20)
Cellular Component
CV term Evidence References
integral to plasma membrane inferred from sequence or structural similarity with EMBL:M68965 AND inferred from sequence or structural similarity with human SCARB2 (Hart and Wilcox, 1993) non-traceable author statement (Lemaitre, 2000.12.20) lysosome inferred from electronic annotation with InterPro:IPR005429 (FlyBase Curators et al., 2004-) plasma membrane non-traceable author statement (Hart, 1993.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions emp allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63567 DroID - A comprehensive database of gene and protein interactions. • FBgn0010435 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37999
Orthologs
OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG64XK2F Dipteran inclusive ortholog search EOG6GMV56 Insect inclusive ortholog search EOG69S52V Arthropod inclusive ortholog search EOG6CNP6K Metazoa inclusive ortholog search EOG686N61
Orthologs in Drosophila Species (EOG64XK2F)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\emp     Drosophila simulans   Dsim\GD24900 Y   Drosophila sechellia   Dsec\GM11768 Y   Drosophila erecta   Dere\GG19866 Y   Drosophila yakuba   Dyak\GE11390 Y   Drosophila ananassae   Dana\GF11514 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15449 Y   Drosophila persimilis   Dper\GL10887 Y   Drosophila willistoni   Dwil\GK19505 Y   Drosophila virilis   Dvir\GJ22260 Y   Drosophila mojavensis   Dmoj\GI19127 Y   Drosophila grimshawi   Dgri\GH22040 Y
Orthologs in non-Drosophila Dipterans (EOG6GMV56)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000256   Anopheles gambiae Malaria mosquito  Agam\SCRB9   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ019101
Orthologs in non-Dipteran Insects (EOG69S52V)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50866   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG025794   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16079   Atta cephalotes Leafcutter ant  Acep\ACEP12643   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15438   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14539   Linepithema humile Argentine ant  Lhum\LH24616   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23580   Solenopsis invicta Red fire ant  Sinv\SINV26479   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007979   Bombyx mori Silkmoth  Bmor\BGIBMGA011153   Pediculus humanus Human body louse  Phum\PHUM569610   Tribolium castaneum Red flour beetle  Tcas\GLEAN_14954
Orthologs in non-Insect Arthropods (EOG6CNP6K)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Upf3b Y Ixodes scapularis Deer tick  Isca\ISCW002412 Y
Orthologs in non-Arthropod Metazoa (EOG686N61)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013903gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025565gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026720gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_003486gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027497gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018904gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24900 Drosophila sechellia Dsec\GM11768 Drosophila erecta Dere\GG19866 Drosophila yakuba Dyak\GE11390 Drosophila ananassae Dana\GF11514 Drosophila pseudoobscura pseudoobscura Dpse\GA15449 Drosophila persimilis Dper\GL10887 Drosophila willistoni Dwil\GK19505 Drosophila virilis Dvir\GJ22260 Drosophila mojavensis Dmoj\GI19127 Drosophila grimshawi Dgri\GH22040
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	23487 w1118; Mi{ET1}empMB02756 18230 w1118; PBac{RB}empe04154/CyO 40947 y1 sc* v1; P{TRiP.HMS02195}attP40
Harvard	- PBac{RB}empe04154 - PBac{WH}empf02107 - PBac{WH}empf07039
VDRC	v12232 w1118; P{GD3569}v12232 v12233 w1118; P{GD3569}v12233
Genomic Clones ( 1 )
	BACR08I14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 111 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH06663 RE08130
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT04774 AT08230 AT15355 AT19290 AT21024 AT21908 AT22230 AT24312 AT25911 AT28001 GH01295 GH01518 GH04945 GH05260 GH08024 GH09276 GH10662 GH15810 GH17733 GH17948 GH19634 GH19992 GH22577 GH25162 GH27157 GH27312 GM06422 GM20920 HL04237 LD37914 LP01673 LP04991 LP06421 LP09805 RE03510 RE06023 RE07367 RE10512 RE18317 RE28618 RE36474 RE40030 RE40063 RE57693 RH23178 RH45079 RH47310 RH53140
Other clones	42465 42713 60229 72890 102061 103157 103325 149448 150077 158219 158526 191856 214513.55 bs14d12 bs34h04 CK01.52B.C6 CK01.92A.G5 CK01.169B.F3 Dmel_dig_009690_0690_1742 Dmel_dig_012634_0711_0470 Dmel_neb_010573_0194_2503 Dmel_neb_011499_0158_3172 EC31441 EK041409 EK042343 EK071927 EK103822 EK157249 EK190940 EK201561 EK208107 EK235910 EK242825 EK243029 EK255925 EK260830 EK261340 EK294413 EP05008 EP10050 ESG013a.E21_D12 ESG013d.E21_F04 ESG017c.E21_H01 ESG0110d.E21_F07 ESG0111b.B21.1_H12 ESG0111c.B21_B02 ESG0111d.B21.1_C01 ESG0113d.B21_A09 FGC017F10 IP15626 LD28416 LD35288 RP004055142 RP004076106 RP004103433 RP004105629 RP004123631 RP004205316 RP004223856 RP004247185 RP004277644
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010435 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37999
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: emp CG2727 (Zhong, 1999.11)
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Cloning and characterisation of emp, expression patterns suggest a role of emp protein in the development or cellular function of epithelial cells. (Hart and Wilcox, 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079135 NM_166702 NM_166703 RefSeq (Proteins) • NP_523859 NP_726504 NP_726505 DDBJ / EMBL / GenBank • AAF47309 AAL47965 AAM70803 AAM70804 AAN71290 AI062346 AI106606 AI403187 AI945580 AI947085 AW940239 AY070494 BI167693 BT001535 CAA51759 CZ481907 CZ481908 CZ484610 CZ489795 X73332 Entrez Gene - A searchable database of RefSeq genes. • 37999 UniProtKB/TrEMBL • Q7KVF1 Q8IGY0 Q8SZV3 Q9W0X0 Q24336
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • CD36 antigen (IPR002159) Adhesion molecule CD36 (IPR005428) Lysosome membrane protein II (IPR005429) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH06663
Linkouts
	BioGRID - A database of protein and genetic interactions • 63567 DroID - A comprehensive database of gene and protein interactions. • FBgn0010435 DRSC - Results from RNAi screens. • FBgn0010435 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010435 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2727-RC FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010435 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37999 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37999 modMine - Data generated by the modENCODE project. • FBgn0010435
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG2727 (Brumby et al., 2004, Nichols and Vogt, 2008, Khanna et al., 2010, Cammarato et al., 2011, Ni et al., 2010.12.1) emp (Ulvila et al., 2006, Nichols and Vogt, 2008, Sackton et al., 2007, Quijano et al., 2008, Vogt et al., 2009, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	epithelial membrane protein (Hart and Wilcox, 1993, Nichols and Vogt, 2008, Cammarato et al., 2011) Epithelial membrane protein (Khanna et al., 2010)
Secondary FlyBase IDs
References ( 40 )
Generate a list of	All references relating to this gene ( 40 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 8 ) Review  ( 2 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 2 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 )
Recent research papers ( 2 )
	Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Herboso et al., 2011, Int. J. Dev. Biol. 55(6): 603--611 Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. [FBrf0216272] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...