• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Srp54k

General Information
Symbol	Dmel\Srp54k	Species	D. melanogaster
Name	Signal recognition particle protein 54k	Annotation symbol	CG4659
Feature type	protein_coding_gene	FlyBase ID	FBgn0010747
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	l(3)01418, Srp54
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64C7-64C7	Sequence location	3L:5,145,669..5,147,877 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Signal recognition particle protein 54k is referred to in FlyBase by the symbol Dmel\Srp54k (CG4659, FBgn0010747). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: signal sequence binding; 7S RNA binding. Based on sequence similarity, it is predicted to be involved in the biological process: SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; SRP-dependent cotranslational protein targeting to membrane. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ATPase, AAA+ type, core; Signal recognition particle, SRP54 subunit; Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, M-domain; Signal recognition particle, SRP54 subunit, helical bundle. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 12-18 embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult fat body, larval/adult salivary gland, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633320_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Srp54k. Gene sequence location is 3L:5145669..5147877.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA11289 BKN20558 Unknown in situ
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64C7-64C7   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References 64C9-64C10   (determined by in situ hybridisation)   (Spradling et al., 1999) 64C9-64C10     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Srp54k for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Srp54k-RA FBtr0077169  NM_079207   2124   508
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Srp54k-PA   FBpp0076872   55.9   508   9.08     NP_523931   AAF50806
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Signal recognition particle, SRP54 subunit, GTPase (IPR000897) ATPase, AAA+ type, core (IPR003593) Signal recognition particle, SRP54 subunit, M-domain (IPR004125) Signal recognition particle, SRP54 subunit (IPR006325) Signal recognition particle, SRP54 subunit, helical bundle (IPR013822)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246376   AA263225   AA264001   AA264229   AA264921   AA390594   AA391330   AA391734   AA438401   AA438713   AA441312   AA536330   AA536331   AA539781   AA695076   AA697234   AA802389   AA820614   AA941315   AA942267   AA942502   AA949529   AA949538   AA949762   AA951103   AA951539   AA978516   AE014296 AAF50806   AF160891 AAD46831   AI107640   AI109029   AI113347   AI512268   AI512277   AI515512   AI531070   AI534124   AI546196   AQ034047   AY094660 AAM11013   BF486246   BF486849   BF488489   BF490528   BF500704   BG633643   BG634160   BG639123   BI163044   BI171699   BI171728   BI172944   BI173709   BI212398   BI215770   BI227582   BI227996   BI233156   BI238841   BI241655   BI243439   BI357660   BI366676   BI367884   BI369174   BI370462   BI371844   BI375486   BI482207   BI485863   BI486648   BI565221   BI577969   BI579007   BI579383   BI579972   BI592440   BI593106   BI612652   BI627383   BI630467   BI631054   BI633417   BI637947   BI637955   BI638929   BI639294   BP540585   BP556866   BX026548   CK657795   CO268794   CO272669   CO272868   CO323347   CO342216   EC235061   EC252252   EL870586   EL870587   EL870589   ES696572   GH747632   GH747672   GH748188   GH748773   GH748985   GH749222   GH750312   GH750557   GH750940   GH753050   GH753749   GH758677   GH770983   GH772366   GH773004   GH775981   GH777676   GH777707   GH777981   GH778359   GH781608   GH782970   GH783155   GH783378   GH783867   GH784523   GH787264   GH787418   GH787676   GH789591   GH789833   GH790706   GH791035   GH794635   GH797094   GH805017   GH805108   GH805352   GH805623   GH805768   GH805948   GH807193   GH807300   GH808124   GH808552   GH809192   GH809967   GH810163   GH811083   GH811124   GH811155   GH813091   GH813804   GH815023   GH816636   GH817413   GH818986   GH819089   GH821603   GH822317   GH824080   GH824908   GH826669   GH832442   GH837440   GH840585   GH840656   GH841801   GH843229   GH847492   GH849829   GH850560   GH851049   GH852455   GH852630   GH853186   GH853705   GH854195   GH856514   GH858126   GH859552   GH860020   GH862857   GH863221   GH869757   GH870146   GH870333   GH877628   GH878526   GH878543   GH879711   GH880130   GH880888   GH881205   GH881228   GH884580   GH887640   GH888818   GH893467   GH903453   GH904786   GH904835   GH906980   GH909781   GH910131   GH910888   GH912079   GH914121   GH917143   GH917383   GH918224   GH918907   GH919059   GH920704   GH921198   GH923248   GH924076   GH925338   GH927049   GH927102   GH934664   GH935115   GH935749   GH936453   GH936850
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T3P8 Q9V3D9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11   salivary gland body primordium   (Abrams and Andrew, 2005) embryonic stage 13 -- 14   presumptive embryonic salivary gland   (Abrams and Andrew, 2005)
Additional Descriptive Data
Marker for
	salivary gland body primordium embryonic salivary gland
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0010747    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0010747 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 12-18 embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0010747 expression level Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr    10852 embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6327) embryo 02-04hr  (9765) embryo 04-06hr  (7774) embryo 06-08hr  (7763) embryo 08-10hr  (8593) embryo 10-12hr  (9750) embryo 12-14hr  (8764) embryo 14-16hr  (10852) embryo 16-18hr  (7607) embryo 18-20hr  (4630) embryo 20-22hr  (5675) embryo 22-24hr  (5317) larva L1  (5902) larva L2  (8122) larva L3 12hr old  (5595) larva L3 puffstage 1-2  (3801) larva L3 puffstage 3-6  (4738) larva L3 puffstage 7-9  (5248) white prepupae new  (5779) white prepupae 12hr  (3429) white prepupae 24hr  (4395) pupae 2d postWPP  (6194) pupae 3d postWPP  (4025) pupae 4d postWPP  (3631) adult male 01day  (4673) adult male 05day  (5135) adult male 30day  (5323) adult female 01day  (4639) adult female 05day  (5336) adult female 30day  (5183) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6327) embryo 02-04hr  (9765) embryo 04-06hr  (7774) embryo 06-08hr  (7763) embryo 08-10hr  (8593) embryo 10-12hr  (9750) embryo 12-14hr  (8764) embryo 14-16hr  (10852) embryo 16-18hr  (7607) embryo 18-20hr  (4630) embryo 20-22hr  (5675) embryo 22-24hr  (5317) larva L1  (5902) larva L2  (8122) larva L3 12hr old  (5595) larva L3 puffstage 1-2  (3801) larva L3 puffstage 3-6  (4738) larva L3 puffstage 7-9  (5248) white prepupae new  (5779) white prepupae 12hr  (3429) white prepupae 24hr  (4395) pupae 2d postWPP  (6194) pupae 3d postWPP  (4025) pupae 4d postWPP  (3631) adult male 01day  (4673) adult male 05day  (5135) adult male 30day  (5323) adult female 01day  (4639) adult female 05day  (5336) adult female 30day  (5183) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr  (10852) embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr    10852 embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0010747 expression level Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr    10852 embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6327) embryo 02-04hr  (9765) embryo 04-06hr  (7774) embryo 06-08hr  (7763) embryo 08-10hr  (8593) embryo 10-12hr  (9750) embryo 12-14hr  (8764) embryo 14-16hr  (10852) embryo 16-18hr  (7607) embryo 18-20hr  (4630) embryo 20-22hr  (5675) embryo 22-24hr  (5317) larva L1  (5902) larva L2  (8122) larva L3 12hr old  (5595) larva L3 puffstage 1-2  (3801) larva L3 puffstage 3-6  (4738) larva L3 puffstage 7-9  (5248) white prepupae new  (5779) white prepupae 12hr  (3429) white prepupae 24hr  (4395) pupae 2d postWPP  (6194) pupae 3d postWPP  (4025) pupae 4d postWPP  (3631) adult male 01day  (4673) adult male 05day  (5135) adult male 30day  (5323) adult female 01day  (4639) adult female 05day  (5336) adult female 30day  (5183) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6327) embryo 02-04hr  (9765) embryo 04-06hr  (7774) embryo 06-08hr  (7763) embryo 08-10hr  (8593) embryo 10-12hr  (9750) embryo 12-14hr  (8764) embryo 14-16hr  (10852) embryo 16-18hr  (7607) embryo 18-20hr  (4630) embryo 20-22hr  (5675) embryo 22-24hr  (5317) larva L1  (5902) larva L2  (8122) larva L3 12hr old  (5595) larva L3 puffstage 1-2  (3801) larva L3 puffstage 3-6  (4738) larva L3 puffstage 7-9  (5248) white prepupae new  (5779) white prepupae 12hr  (3429) white prepupae 24hr  (4395) pupae 2d postWPP  (6194) pupae 3d postWPP  (4025) pupae 4d postWPP  (3631) adult male 01day  (4673) adult male 05day  (5135) adult male 30day  (5323) adult female 01day  (4639) adult female 05day  (5336) adult female 30day  (5183) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr  10852 embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6327 embryo 02-04hr    9765 embryo 04-06hr    7774 embryo 06-08hr    7763 embryo 08-10hr    8593 embryo 10-12hr    9750 embryo 12-14hr    8764 embryo 14-16hr    10852 embryo 16-18hr    7607 embryo 18-20hr    4630 embryo 20-22hr    5675 embryo 22-24hr    5317 larva L1    5902 larva L2    8122 larva L3 12hr old    5595 larva L3 puffstage 1-2    3801 larva L3 puffstage 3-6    4738 larva L3 puffstage 7-9    5248 white prepupae new    5779 white prepupae 12hr    3429 white prepupae 24hr    4395 pupae 2d postWPP    6194 pupae 3d postWPP    4025 pupae 4d postWPP    3631 adult male 01day    4673 adult male 05day    5135 adult male 30day    5323 adult female 01day    4639 adult female 05day    5336 adult female 30day    5183 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0010747    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0010747 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult fat body, larval/adult salivary gland, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0010747 expression level Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland    1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland  (922.3) Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body  519.8 Adult Salivary Gland  (1002.8) Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland  (687.8) Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland  1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland    1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0010747 expression level Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland    1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland  (922.3) Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body  519.8 Adult Salivary Gland  (1002.8) Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland  687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland  1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    303.3 Larval Midgut    284 Larval Hindgut    357.1 Larval Malpighian Tubules    296.8 Larval Fat Body    314.2 Larval Salivary Gland    922.3 Larval Trachea    365.45 Larval Carcass    351.775 Adult Head    245.9 Adult Eye    131.875 Adult Brain    195.5 Adult Thoracic-Abdominal Ganglion    194.5 Adult Crop    279.5 Adult Midgut    289.3 Adult Hindgut    286.6 Adult Malpighian Tubules    465.5 Adult Fat Body    519.8 Adult Salivary Gland    1002.8 Adult Heart    269.075 Adult VirginFemale Spermatheca    448.5 Adult InseminatedFemale Spermatheca    483.6 Adult Ovary    280.8 Adult Testis    318.2 Adult Male Accessory Gland    687.8 Adult Carcass    271.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    245.9   NA  Eye    131.875   NA  Brain    195.5   303.3  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    194.5   NA  Crop    279.5   284  Midgut    289.3   357.1  Hindgut    286.6   296.8  Malpighian Tubules    465.5   314.2  Fat Body    519.8   922.3  Salivary Gland    1002.8   NA  Heart    269.075   365.45  Trachea    NA   NA  VirginFemale Spermatheca    448.5   NA  InseminatedFemale Spermatheca    483.6   NA  Ovary    280.8   NA  Testis    318.2   NA  Male Accessory Gland    687.8   351.775  Carcass    271.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010747 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4659-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 Srp54kGD1542 lethal | recessive Srp54k01418 Phenotype manifest in Allele autophagic vacuole & larval fat body | somatic clone | cell autonomous, with Scer\GAL4Act5C.PP Srp54kGD1542 lysosome & larval fat body | somatic clone | cell autonomous, with Scer\GAL4Act5C.PP Srp54kGD1542
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Srp54k Class Mutagen Stocks Known lesion Srp54k01418 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Srp54k Class Mutagen Stocks Known lesion Srp54kGD1542 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes Srp54kKK100462 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6103 (Ryder, 2004.4.26) Df(3L)GN24 (Spradling et al., 1999, BDGP Project Members, 1994-1999, Spradling et al., 1995) Df(3L)ZN47 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1542} NA P{KK100462} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}Srp54k01418 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
7S RNA binding inferred from sequence or structural similarity with UniProtKB:P14576 (FlyBase, 1992-) GTP binding inferred from electronic annotation with InterPro:IPR000897, InterPro:IPR006325, InterPro:IPR013822 (FlyBase Curators et al., 2004-) nucleoside-triphosphatase activity inferred from electronic annotation with InterPro:IPR003593 (FlyBase Curators et al., 2004-) signal sequence binding inferred from sequence or structural similarity (Spradling et al., 1999)
Biological Process
CV term Evidence References
SRP-dependent cotranslational protein targeting to membrane inferred from sequence or structural similarity with UniProtKB:P14576 (FlyBase, 1992-) SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition inferred from sequence or structural similarity (Spradling et al., 1999)
Cellular Component
CV term Evidence References
signal recognition particle, endoplasmic reticulum targeting inferred from sequence or structural similarity (Spradling et al., 1999) inferred from sequence or structural similarity with UniProtKB:P14576 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Srp54k allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64061 DroID - A comprehensive database of gene and protein interactions. • FBgn0010747 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38593
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23972 Dere\GG15264 Dgri\GH16182 Dmoj\GI13333 Dper\GL22620 Dpse\GA18336 Dsec\GM14699 Dsim\GD13881 Dvir\GJ13160 Dwil\GK20323 Dyak\GE21487
Curated drosophilid orthologs	Dpse\GA18336
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013076-PA Aedes aegypti (mosquito) AGAP004610-PA Anopheles gambiae (mosquito) XP_624497.2 Apis mellifera (honey bee) XP_001951515.1 Acyrthosiphon pisum (pea aphid) At1g48900.1 Arabidopsis thaliana (wall cress) 86146 Batrachochytrium dendrobatidis (chytrid fungus) 60686 Branchiostoma floridae (lancelet) XP_001895013.1 Brugia malayi (roundworm nematode) BGIBMGA004993-PA Bombyx mori (silk worm) ENSBTAP00000025405 Bos taurus (bovine) CAL0003314 Candida albicans (a form of yeast) CBP28609 Caenorhabditis briggsae (nematode) CE09524 Caenorhabditis elegans (worm) ENSCAFP00000019649 Canis familiaris (dog) CAGL0K07986g Candida glabrata (haploid yeast) Chro.70193 Cryptosporidium hominis (obligate parasite) ENSCINP00000015156 Ciona intestinalis (sea squirt) JA06792 Caenorhabditis japonica (nematode) CMO152C Cyanidioschyzon merolae (red alga) cn05368 Cryptococcus neoformans (yeast-like fungus) cgd7_1640 Cryptosporidium parvum (protozoan parasite) CPIJ009377 Culex pipens (mosquito) ENSCPOP00000003331 Cavia porcellus (guinea pig) 127491 Chlamidomonas reinhardtii (green alga) RP31944 Caenorhabditis remanei (nematode) 160274 Capitella spl (polychaete worm) DDB0232373 Dictyostelium discoideum (amoeba) DEHA2E19404g Debaryomyces Hansenii (yeast) 325390 Daphnia pulex (daphnia) ENSDARP00000004721 Danio rerio (zebra fish) ENSECAP00000016030 Equus caballus (horse) NP_417101.1 Escherichia coli K12 (bacteria) XP_650715 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005615 Gymnopilus aculeatus (mushroom) ENSGALP00000016308 Gallus gallus (chicken) GL50803_15156 Giardia lamblia (flagellated protozoan) 189679 Hypsipyla robusta (cedar shoot borer) ENSP00000216774 Homo sapiens (human) KLLA0D09020g Kluyveromyces lactis (yeast) 127402 Lottia gigantea (owl limpet) LmjF24.0730 Leishmania major (virus) 33939 Monocosta brevicollis (choanoflagellate) ENSMODP00000016172 Monodelphis domestica (gray opossum) ENSMODP00000016174 Monodelphis domestica (gray opossum) ENSMMUP00000019755 Macaca mulatta (rhesus monkey) ENSMUSP00000021407 Mus musculus (house mouse) ENSMUSP00000098963 Mus musculus (house mouse) 238119 Nematostella vectensis (starlet anemone) XP_001604233.1 Nasonia vitripennis (wasp) ENSOANP00000022161 Ornithorynchus anatinus (platypus) LOC_Os01g56600.1 Oryza sativa (asian rice) 35033 Ostreococcus tauri (green alga) PF14_0477 Plasmodium falciparum (protozoal parasite) PHUM001787-PA Pediculus humanus (human body louse) PP04722 Pristionchus pacificus (nematode) 160785 Physcomitrella patens (moss) ENSPPYP00000006521 Pongo pygmaeus (orangutan) 71732 Phytophthora ramorum (sudden oak death pathogen) 111588 Phytophthora sojae (root rot pathogen) 172222 Populus trichocarpa (black cottonwood) ENSPTRP00000010626 Pan troglodytes (chimpanzee) PVX_117980 Plasmodium vivax (protozoal parasite) ENSRNOP00000040194 Rattus norvegicus (norway rat) 4880157 Sorghum bicolor (sorghum) YPR088C Saccharomyces cerevisiae (budding yeast) Smp_059540 Schistosoma mansoni (trematode parasite) SPCC188.06c Schizosaccharomyces pombe (fission yeast) XP_001185704.1 Strongylocentrotus purpuratus (purple sea urchin) 36767 Trichoplax adhaerens (metazoa) TA06010 Theileria annulata (apicomplexan parasite) XP_967889.1 Tribolium castaneum (red flour beetle) Tc00.1047053505183.80 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005141 Tetraodon nigroviridis (green spotted pufferfish) TP01_0852 Theileria parva (parasitic protozoan) 260805 Thalassiosira pseudonana (marine diatom) ENSTRUP00000017336 Takifugu rubripes (pufferfish Takifugu) 3695.m00025 Tetrahymena thermophila (ciliate protozoa) 91877.m00061 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000026869 Xenopus tropicalis (frog) YALI0F03839g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11136 NV16343 LH22218 ISCW009113 FBgn0238744 FBgn0222320 FBgn0200387 FBgn0185577 FBgn0169620 JGI_V11_325390 FBgn0078341 FBgn0160211 FBgn0136090 FBgn0123653 FBgn0107516 FBgn0100966 CPIJ009377 BGIBMGA004993 ACYPI000610 GB30580 GB10148 AGAP004610 AAEL013076 AAEL007400 PHUM194960 GLEAN_02574
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v42852 w1118; P{GD1542}v42852 v46199 w1118; P{GD1542}v46199 v42851 w1118; P{GD1542}v42851/TM3
Genomic Clones ( 1 )
	BACR12G07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 219 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT23778 GM09489
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT15704 AT20485 AT21390 AT27022 AT30268 GH05243 GH05431 GH07526 GM02095 LD05248 LD06332 LD07389 LD07896 LD08571 LD09683 LD09865 LD11672 LD12675 LD13051 LD16201 LD16888 LD16890 LD18115 LD24431 LD25385 LD26375 LD26754 LD28362 LD28373 LD30754 LD31390 LD32087 LD44058 LD47262 LD47377 LP24368 RE02341 RE13528 RE13559 RE15653 RE16792 RE17485 RE22373 RE24671 RE25401 RE29444 RE38773 RE41081 RE41925 RE44190 RE52263 RE53750 RE55281 RE56985 RE58851 RE63319 RE64865 RE69214 RE70103 RE71750 RE72970 RE73408 RE74084 RH10131 RH11011 RH41587 RH59516 RH60458 RH62935 RH68676 SD01950 SD06639 SD20134 SD20152 SD21334 SD21845 SD27492
Other clones	63305 214377.19 EK092704 EK108008 EK108608 EK190261 EP14156 FGA006A08 FGM306A02 GM04639 IP02649 IP02650 IP02652 LD29769 LD44046 RP003003612 RP003003910 RP003006384 RP003011167 RP003011911 RP003012064 RP003013642 RP003018510 RP003018598 RP003019604 RP003020088 RP003022087 RP003022816 RP003025178 RP003031290 RP003032243 RP003037716 RP003038809 RP003041893 RP003042504 RP003047752 RP003054763 RP003058387 RP003065006 RP003068838 RP003072847 RP003074622 RP003077200 RP003083584 RP003084728 RP003085443 RP003088941 RP003090160 RP003091591 RP003095422 RP003095638 RP003104852 RP003105418 RP003106500 RP003117805 RP003121705 RP003126129 RP003139326 RP003141833 RP003142446 RP003156446 RP003159264 RP003166242 RP003167499 RP003169459 RP003170899 RP003173233 RP003174810 RP003176014 RP003185882 RP003190333 RP003193756 RP003204369 RP003212481 RP003216606 RP003216725 RP003221942 RP003226101 RP003231352 RP003246321 RP003252274 RP003259842 RP003260531 RP003260949 RP003266092 RP003267659 RP003269725 RP003275094 RP003281776 RP003282198 RP003290990 RP003292138 RP003300144 RP003307098 RP003312005 RP003314425 RP003332036 RP003335457 RP003337461 RP003348625 RP003357231 RP003363276 RP003364988 RP003366501 RP003372986 RP003386698 RP003390680 RP003393166 RP003400763 RP003401037 RP003405681 RP003413867 RP003422208 RP003425941 RP003428468 RP003429322 RP003430058 RP003447537 RP003466820 RP003479159 RP003482726 RP003488218 RP003489556 RP003493809 RP003522529 RP003524798 RP003530842 RP003532670 RP003532985 RP003541998 RP003545577 RP003547360 RP003550094 RP003559072 RP003565100 RP003582569 RP003583983 RP003613193 RP003646690 RP003663321
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010747 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38593
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Srp54k CG4659 (Gabrielian, 1999.11)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079207 RefSeq (Proteins) • NP_523931 DDBJ / EMBL / GenBank • AA697234 AAD46831 AAF50806 AAM11013 AF160891 AQ034047 AY094660 BF488489 Entrez Gene - A searchable database of RefSeq genes. • 38593 UniProtKB/TrEMBL • Q8T3P8 Q9V3D9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Signal recognition particle, SRP54 subunit, GTPase (IPR000897) ATPase, AAA+ type, core (IPR003593) Signal recognition particle, SRP54 subunit, M-domain (IPR004125) Signal recognition particle, SRP54 subunit (IPR006325) Signal recognition particle, SRP54 subunit, helical bundle (IPR013822)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64061 DroID - A comprehensive database of gene and protein interactions. • FBgn0010747 DRSC - Results from RNAi screens. • FBgn0010747 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010747 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4659-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010747 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38593 InParanoid A subset of ortholog calls from InParanoid. • AAEL013076-PA Aedes aegypti (mosquito) AGAP004610-PA Anopheles gambiae (mosquito) XP_624497.2 Apis mellifera (honey bee) XP_001951515.1 Acyrthosiphon pisum (pea aphid) At1g48900.1 Arabidopsis thaliana (wall cress) 86146 Batrachochytrium dendrobatidis (chytrid fungus) 60686 Branchiostoma floridae (lancelet) XP_001895013.1 Brugia malayi (roundworm nematode) BGIBMGA004993-PA Bombyx mori (silk worm) ENSBTAP00000025405 Bos taurus (bovine) CAL0003314 Candida albicans (a form of yeast) CBP28609 Caenorhabditis briggsae (nematode) CE09524 Caenorhabditis elegans (worm) ENSCAFP00000019649 Canis familiaris (dog) CAGL0K07986g Candida glabrata (haploid yeast) Chro.70193 Cryptosporidium hominis (obligate parasite) ENSCINP00000015156 Ciona intestinalis (sea squirt) JA06792 Caenorhabditis japonica (nematode) CMO152C Cyanidioschyzon merolae (red alga) cn05368 Cryptococcus neoformans (yeast-like fungus) cgd7_1640 Cryptosporidium parvum (protozoan parasite) CPIJ009377 Culex pipens (mosquito) ENSCPOP00000003331 Cavia porcellus (guinea pig) 127491 Chlamidomonas reinhardtii (green alga) RP31944 Caenorhabditis remanei (nematode) 160274 Capitella spl (polychaete worm) DDB0232373 Dictyostelium discoideum (amoeba) DEHA2E19404g Debaryomyces Hansenii (yeast) 325390 Daphnia pulex (daphnia) ENSDARP00000004721 Danio rerio (zebra fish) ENSECAP00000016030 Equus caballus (horse) NP_417101.1 Escherichia coli K12 (bacteria) XP_650715 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000005615 Gymnopilus aculeatus (mushroom) ENSGALP00000016308 Gallus gallus (chicken) GL50803_15156 Giardia lamblia (flagellated protozoan) 189679 Hypsipyla robusta (cedar shoot borer) ENSP00000216774 Homo sapiens (human) KLLA0D09020g Kluyveromyces lactis (yeast) 127402 Lottia gigantea (owl limpet) LmjF24.0730 Leishmania major (virus) 33939 Monocosta brevicollis (choanoflagellate) ENSMODP00000016172 Monodelphis domestica (gray opossum) ENSMODP00000016174 Monodelphis domestica (gray opossum) ENSMMUP00000019755 Macaca mulatta (rhesus monkey) ENSMUSP00000021407 Mus musculus (house mouse) ENSMUSP00000098963 Mus musculus (house mouse) 238119 Nematostella vectensis (starlet anemone) XP_001604233.1 Nasonia vitripennis (wasp) ENSOANP00000022161 Ornithorynchus anatinus (platypus) LOC_Os01g56600.1 Oryza sativa (asian rice) 35033 Ostreococcus tauri (green alga) PF14_0477 Plasmodium falciparum (protozoal parasite) PHUM001787-PA Pediculus humanus (human body louse) PP04722 Pristionchus pacificus (nematode) 160785 Physcomitrella patens (moss) ENSPPYP00000006521 Pongo pygmaeus (orangutan) 71732 Phytophthora ramorum (sudden oak death pathogen) 111588 Phytophthora sojae (root rot pathogen) 172222 Populus trichocarpa (black cottonwood) ENSPTRP00000010626 Pan troglodytes (chimpanzee) PVX_117980 Plasmodium vivax (protozoal parasite) ENSRNOP00000040194 Rattus norvegicus (norway rat) 4880157 Sorghum bicolor (sorghum) YPR088C Saccharomyces cerevisiae (budding yeast) Smp_059540 Schistosoma mansoni (trematode parasite) SPCC188.06c Schizosaccharomyces pombe (fission yeast) XP_001185704.1 Strongylocentrotus purpuratus (purple sea urchin) 36767 Trichoplax adhaerens (metazoa) TA06010 Theileria annulata (apicomplexan parasite) XP_967889.1 Tribolium castaneum (red flour beetle) Tc00.1047053505183.80 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005141 Tetraodon nigroviridis (green spotted pufferfish) TP01_0852 Theileria parva (parasitic protozoan) 260805 Thalassiosira pseudonana (marine diatom) ENSTRUP00000017336 Takifugu rubripes (pufferfish Takifugu) 3695.m00025 Tetrahymena thermophila (ciliate protozoa) 91877.m00061 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000026869 Xenopus tropicalis (frog) YALI0F03839g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38593 modMine - Data generated by the modENCODE project. • FBgn0010747 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11136 NV16343 LH22218 ISCW009113 FBgn0238744 FBgn0222320 FBgn0200387 FBgn0185577 FBgn0169620 JGI_V11_325390 FBgn0078341 FBgn0160211 FBgn0136090 FBgn0123653 FBgn0107516 FBgn0100966 CPIJ009377 BGIBMGA004993 ACYPI000610 GB30580 GB10148 AGAP004610 AAEL013076 AAEL007400 PHUM194960 GLEAN_02574
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	BcDNA:GM09489   BcDNA.GM09489 (Tsang, 1999.6.19) CG4659 (Abrams and Andrew, 2005, Keleman et al., 2009.8.5) l(3)01418 (Beaton, 2000.1.31, Spradling et al., 1995, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999, ) Srp54 (Abrams and Andrew, 2005, Spradling et al., 1999, Arsham and Neufeld, 2009) Srp54k (Stuart et al., 2007, Avet-Rochex et al., 2010)
Name Synonym	Signal recognition particle protein 54k (Spradling et al., 1999)
Secondary FlyBase IDs
	FBgn0027916
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 3 ) Review  ( 1 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 2 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 2 )
	Avet-Rochex et al., 2010, BMC Dev. Biol. 10: 65 An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. [FBrf0211137] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...