Atro, Atrophin, l(3)03928, l(3)01323
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gug using the Feature Mapper tool.
In early embryos, Gug protein is ubiquitously expressed in all cells, where it is localized to the nucleus. In later embryos, Gug protein expression is at a higher level in the CNS. Gug protein is detected in all larval tissues, including imaginal discs, the brain, and the optic lobes.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Gug in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Gug is required in diverse developmental processes including early embryo patterning.