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Gene Dmel\sinu

General Information
Symbol	Dmel\sinu	Species	D. melanogaster
Name	sinuous	Annotation symbol	CG10624
Feature type	protein_coding_gene	FlyBase ID	FBgn0010894
Gene Model Status	Current	Stock availability	9 publicly available
Also Known As	l(3)06524
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	64D3-64D3	Sequence location	3L:5,552,570..5,554,698 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene sinuous is referred to in FlyBase by the symbol Dmel\sinu (CG10624, FBgn0010894). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: regulation of tube size, open tracheal system; establishment of glial blood-brain barrier; open tracheal system development; septate junction assembly. 13 alleles are reported. The phenotypes of these alleles are annotated with: taenidial fold; trichogen cell; embryonic/larval dorsal trunk; septate junction; heart primordium; presumptive embryonic/larval tracheal system; embryonic/larval tracheal system; dorsal trunk primordium; embryonic/larval transverse connective. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult hindgut, larval/adult salivary gland, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval midgut, larval fat body, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637014_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of sinu. Gene sequence location is 3L:5552570..5554698.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 64D3-64D3   Limits computationally determined from genome sequence between P{PZ}l(3)rG166rG166 and P{PZ}sinu06524
Experimentally Determined Cytological Location
Cytogenetic map Notes References 64D3-64D4   (determined by in situ hybridisation)   (Beitel and Krasnow, 2000) 64D3-64D4   (determined by in situ hybridisation)   (Spradling et al., 1999) 64D3-64D4     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sinu for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sinu-RA FBtr0077136  NM_139714   2065   247 sinu-RB FBtr0300070  NM_001144419   1943   263
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sinu-PA   FBpp0076842   27.7   247   9.28     NP_647971   AAF50772 sinu-PB   FBpp0289347   29.5   263   10.26     NP_001137891   ACL83246
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141869   AA141870   AE014296 AAF50772   AE014296 ACL83246   AQ034069   AY069562   AY423544 AAR24293   BI165890   BI166198   BI170948   BI171786   BI172488   BI232439   BI232797   BI237702   BI238900   BI363397   BI364981   BI365623   BI485114   BI486882   BI577902   BI578068   BP547806   BP555718   CF674929   CF674930   CF674931   CF674932   CF674933   CF674934   CF674935   CF674936   CF674937   CF674938   CK657782   CO185610   CO265548   CO270830   CO270857   CO271759   CO278124   CO280497   CO281889   CO282053   CO284963   CO292660   CO293470   CO294228   CO295366   CO295768   CO299251   CO303563   CO304835   CO310952   CO314862   CO320920   CO330226   CO331310   CO332529   CO338643   CZ482228   CZ482229   EC061675   EC063756   EC073811   EC075138   EC076884   EC077138   EC078891   EC082978   EC084299   EC197385   EC201561   EC208597   EC208770   EC209969   EC210685   EC210885   EC212938   EC216740   EC224694   EC234557   EC238362   EC239281   EC248057   EC257109   EC263526   FE863493   FE863624   FE863709   FE863757   FE863816   GH740913   GH741092   GH763300   GH763568   GH767736
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VRM3 B7Z0C1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   dorsal epidermis primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic dorsal epidermis   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic optic lobe   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
septate junction inferred from direct assay (Wu et al., 2004)
Expression Deduced from Reporters
Reporter: P{PZ}sinu06524 Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage   embryonic/larval optic lobe   (Harvie et al., 1998) ventral nerve cord   (Harvie et al., 1998) eye disc   (Harvie et al., 1998) ring gland   (Harvie et al., 1998) embryonic/larval hindgut   (Meister and Braun, 1995.10)
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult hindgut, larval/adult salivary gland, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval midgut, larval fat body, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea    1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut  (638.4) Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland  (776.9) Larval Trachea  (1057.7) Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop  (676.1) Adult Midgut    86.7 Adult Hindgut  (616.1) Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland  (577.5) Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea  1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea    1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea    1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut  638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland  776.9 Larval Trachea  (1057.7) Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop  676.1 Adult Midgut    86.7 Adult Hindgut  616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland  577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea  1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    205.4 Larval Midgut    102.4 Larval Hindgut    638.4 Larval Malpighian Tubules    60.6 Larval Fat Body    103.9 Larval Salivary Gland    776.9 Larval Trachea    1057.7 Larval Carcass    391.075 Adult Head    197.2 Adult Eye    254.925 Adult Brain    120.1 Adult Thoracic-Abdominal Ganglion    124.1 Adult Crop    676.1 Adult Midgut    86.7 Adult Hindgut    616.1 Adult Malpighian Tubules    76.6 Adult Fat Body    82.9 Adult Salivary Gland    577.5 Adult Heart    59.975 Adult VirginFemale Spermatheca    228.4 Adult InseminatedFemale Spermatheca    414.8 Adult Ovary    202.5 Adult Testis    114.2 Adult Male Accessory Gland    492.8 Adult Carcass    160.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    197.2   NA  Eye    254.925   NA  Brain    120.1   205.4  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    124.1   NA  Crop    676.1   102.4  Midgut    86.7   638.4  Hindgut    616.1   60.6  Malpighian Tubules    76.6   103.9  Fat Body    82.9   776.9  Salivary Gland    577.5   NA  Heart    59.975   1057.7  Trachea    NA   NA  VirginFemale Spermatheca    228.4   NA  InseminatedFemale Spermatheca    414.8   NA  Ovary    202.5   NA  Testis    114.2   NA  Male Accessory Gland    492.8   391.075  Carcass    160.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (60) central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae  (40) digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering  (42) carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (60) central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae  (40) digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering  (42) carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    60 central nervous system, larvae L3    21 central nervous system, pupae P8    24 head, virgin 1-day female    12 head, virgin 4-day female    8 head, virgin 20-day female    8 head, mated 1-day female    11 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    14 head, mated 4-day male    18 head, mated 20-day male    18 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    5 digestive system, 4-day adult    7 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    14 fat body, pupae P8    23 carcass, larvae L3 wandering    42 carcass, 1-day adult    11 carcass, 4-day adult    13 carcass, 20-day adult    9 ovary, virgin 4-day female    22 ovary, mated 4-day female    12 testis, mated 4-day male    11 accessory gland, mated 4-day male    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr    106 embryo 12-14hr    107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr  (32) embryo 06-08hr  (55) embryo 08-10hr  (78) embryo 10-12hr  (106) embryo 12-14hr  (107) embryo 14-16hr  (59) embryo 16-18hr  (60) embryo 18-20hr  (38) embryo 20-22hr    22 embryo 22-24hr  (30) larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9  (34) white prepupae new  (34) white prepupae 12hr  (31) white prepupae 24hr  (41) pupae 2d postWPP  (31) pupae 3d postWPP  (36) pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr  106 embryo 12-14hr  107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr    106 embryo 12-14hr    107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr    106 embryo 12-14hr    107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr  32 embryo 06-08hr  (55) embryo 08-10hr  (78) embryo 10-12hr  (106) embryo 12-14hr  (107) embryo 14-16hr  (59) embryo 16-18hr  (60) embryo 18-20hr  (38) embryo 20-22hr    22 embryo 22-24hr  30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9  (34) white prepupae new  (34) white prepupae 12hr  31 white prepupae 24hr  (41) pupae 2d postWPP  31 pupae 3d postWPP  (36) pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr  106 embryo 12-14hr  107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8 embryo 02-04hr    18 embryo 04-06hr    32 embryo 06-08hr    55 embryo 08-10hr    78 embryo 10-12hr    106 embryo 12-14hr    107 embryo 14-16hr    59 embryo 16-18hr    60 embryo 18-20hr    38 embryo 20-22hr    22 embryo 22-24hr    30 larva L1    15 larva L2    13 larva L3 12hr old    9 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    19 larva L3 puffstage 7-9    34 white prepupae new    34 white prepupae 12hr    31 white prepupae 24hr    41 pupae 2d postWPP    31 pupae 3d postWPP    36 pupae 4d postWPP    8 adult male 01day    9 adult male 05day    7 adult male 30day    8 adult female 01day    7 adult female 05day    9 adult female 30day    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1  (32) embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  (30) eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2  (53) tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1  32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2  (53) tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    15 Schneider line 2 Sg4    14 embryonic 1182-4H    11 embryonic GM2    17 embryonic Kc167    10 embryonic S1    32 embryonic S3    8 leg disc CME L1    6 wing disc CME-W2    23 wing disc ML-DmD8    17 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    13 wing disc ML-DmD21    18 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    30 eye-antennal disc ML-DmD11    10 antennal disc ML-DmD20-c5    24 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    53 tumorous blood cells mbn2    21 ovary fGS/OSS    7 ovary OSC    11 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3  (32) Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3  32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    3 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    10 Cadmium 50 mM 12 hrs, larvae L3    32 Cadmium 50 mM 48 hrs, 4-day adult    12 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    6 Ethanol 5% 3 hrs, larvae L3    23 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    24 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    12 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    19 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_11 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • PC00127 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010894 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10624-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for sinu Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 sinuGD2315 lethal | recessive sinu06524 partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 sinuGD2315 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 sinuGD2315 Phenotype manifest in Allele dorsal trunk primordium sinu06524 embryonic/larval dorsal trunk sinu06524 embryonic/larval tracheal system sinu06524 sinunwu7 embryonic/larval transverse connective sinu06524 heart primordium sinudsRNA.cKa sinudsRNA.si.cKa presumptive embryonic/larval tracheal system sinudsRNA.cWa septate junction sinunwu7 taenidial fold sinunwu7 trichogen cell, with Scer\GAL4pnr-MD237 sinuGD2315
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of sinu Class Mutagen Stocks Known lesion sinu06524 loss of function allele P-element activity 1 Yes sinue04469 piggyBac transposase 1 -- sinuMI06254 1 -- sinunwu7 P-element activity 1 Yes sinue03392 0 -- sinuunspecified 0 --
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sinu Class Mutagen Stocks Known lesion sinuGD2315 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes sinuGL00639 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sinuHMS01702 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sinudsRNA.cKa in vitro construct - RNAi 0 Yes sinudsRNA.cWa in vitro construct - RNAi 0 Yes sinudsRNA.si.cKa in vitro construct - RNAi 0 Yes sinuScer\UAS.cWa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)BSC372 (Christensen et al., 2007.10.29) Df(3L)BSC387 (Christensen et al., 2007.10.29) Df(3L)BSC557 (Christensen et al., 2008.7.11) Df(3L)Exel6105 (Ryder, 2004.4.26) Df(3L)sinunwu7 (Wu et al., 2004) Df(3L)ZN47 (Spradling et al., 1999, Beitel and Krasnow, 2000, BDGP Project Members, 1994-1999)
Not disrupted in	Df(3L)GN24 (Spradling et al., 1999, BDGP Project Members, 1994-1999, Spradling et al., 1995)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2315} NA P{TRiP.GL00639} NA P{TRiP.HMS01702} NA P{UAS-sinu.W} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}sinu06524 No miscellaneous insertions Mi{MIC}sinuMI06254 NA PBac{RB}sinue03392 NA PBac{RB}sinue04469 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
establishment of glial blood-brain barrier inferred from mutant phenotype (Stork et al., 2008) open tracheal system development inferred from mutant phenotype (Beitel and Krasnow, 2000) regulation of tube size, open tracheal system inferred from mutant phenotype (Beitel and Krasnow, 2000) septate junction assembly inferred from mutant phenotype (Wu et al., 2004)
Cellular Component
CV term Evidence References
septate junction inferred from direct assay (Wu et al., 2004)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
septate junction assembly non-traceable author statement (Wu, 2003.9.26)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sinu allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 70122 DroID - A comprehensive database of gene and protein interactions. • FBgn0010894 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 46187
Orthologs
OrthoDB Orthologs (40) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6KH3FC Dipteran inclusive ortholog search EOG6S4PR8 Insect inclusive ortholog search EOG6W3RJH Arthropod inclusive ortholog search EOG6ZS7KM Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6KH3FC)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\sinu     Drosophila simulans   Dsim\GD13191 Y   Drosophila sechellia   Dsec\GM13914 Y   Drosophila erecta   Dere\GG14127 Y   Drosophila yakuba   Dyak\GE20553 Y   Drosophila ananassae   Dana\GF10459 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10446 Y   Drosophila persimilis   Dper\GL12049 Y   Drosophila willistoni   Dwil\GK17307 Y   Drosophila virilis   Dvir\GJ11958 Y   Drosophila mojavensis   Dmoj\GI13182 Y   Drosophila grimshawi   Dgri\GH16247 Y
Orthologs in non-Drosophila Dipterans (EOG6S4PR8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005218   Anopheles gambiae Malaria mosquito  Agam\AGAP003809   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011110
Orthologs in non-Dipteran Insects (EOG6W3RJH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54254 Y Apis mellifera Western honey bee  Amel\GB54255 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG015605 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG015604 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13077 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13078 Y Atta cephalotes Leafcutter ant  Acep\ACEP12245 Y Atta cephalotes Leafcutter ant  Acep\ACEP12249 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18551 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18552 Y Linepithema humile Argentine ant  Lhum\LH20695 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16522 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16523 Y Solenopsis invicta Red fire ant  Sinv\SINV17149 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI004344 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI006751 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008414 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007750 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007749 Y Pediculus humanus Human body louse  Phum\PHUM302480 Y Tribolium castaneum Red flour beetle  Tcas\TC014460 Y Tribolium castaneum Red flour beetle  Tcas\TC014461 Y
Orthologs in non-Insect Arthropods (EOG6ZS7KM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\NLGN3 Y Daphnia pulex Water flea  Dpux\HTRA4 Y Ixodes scapularis Deer tick  Isca\ISCW023960 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13191 Drosophila sechellia Dsec\GM13914 Drosophila erecta Dere\GG14127 Drosophila yakuba Dyak\GE20553 Drosophila ananassae Dana\GF10459 Drosophila pseudoobscura pseudoobscura Dpse\GA10446 Drosophila persimilis Dper\GL12049 Drosophila willistoni Dwil\GK17307 Drosophila virilis Dvir\GJ11958 Drosophila mojavensis Dmoj\GI13182 Drosophila grimshawi Dgri\GH16247
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	38200 y1 sc* v1; P{TRiP.GL00639}attP40 38258 y1 sc* v1; P{TRiP.HMS01702}attP40 11690 P{PZ}sinu06524 ry506/TM3, ryRK Sb1 Ser1 42142 y1 w*; Mi{MIC}sinuMI06254/TM3, Sb1 Ser1 8577 w*; sinunwu7/TM6B, P{HZ2.7}3, Sb1 Tb1 ca1
Harvard	- PBac{RB}sinue04469
VDRC	v9012 w1118 P{GD2315}v9012 v44928 w1118; P{GD2315}v44928 v44929 w1118; P{GD2315}v44929
Genomic Clones ( 1 )
	BACR11E06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 81 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD29359
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP24349 RE05881 RE06244 RE12582 RE13637 RE14995 RE28506 RE28927 RE33979 RE42018 RE48192 RE50192 RE50986 RE68393 RE70362 RE71666 RE71866
Other clones	17043 32786 37864 39951 44164 51766 56291 72408 73617 78256 78761 79483 100303 118829 122179 158650 183833 191554 214439.14 281944 572879 CK01.123D.C11 CK01.130D.F9 CK01.131A.H4 CK01.168A.A10 EK010505 EK100423 EK100662 EK104526 EK128924 EK142924 EK154214 EK159027 EK159426 EK167736 EK174915 EK200713 EK202960 EK206355 EK209601 EK211541 EK223035 EK238112 EK242115 EK246507 EK288764 EK294750 EK299042 EK303805 EN17251 FGH120H06 FGM236G06 RE12528 RM07414 RM07614 RM07714 RM07814 RM07914 RP001004820 RP001037934 RP001051160 RP001052247 RP001052437
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0010894 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 46187
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: sinu l(3)06524 (Beitel and Krasnow, 2000)
Source for database merge of	Source for merge of: sinu CG10624 (Wu, 2002.3.18)
Additional comments
Other Comments
	The predicted gene structure and sequence of the release 3.1 annotation for sinu is based on an aberrantly spliced cDNA which has a novel and probably irrelevant C-terminal sequence. The correct structure and sequence for sinu gene product is given by the representative cDNA with accession number AY423544. (Beitel, 2004.2.25) sinu is required for septate junction organisation and paracellular barrier formation. (Wu et al., 2004) Mutation in sinu alters tracheal tube size in embryos without affecting other aspects of tracheal development including primary branch budding and outgrowth or branch fusion. (Beitel and Krasnow, 2000) Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland. (Harvie et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139714 NM_001144419 RefSeq (Proteins) • NP_647971 NP_001137891 DDBJ / EMBL / GenBank • AA141869 AA141870 AAF50772 AAF50772.2 AAR24293 ACL83246 AQ034069 AY423544 CF674929 CF674930 CF674931 CF674932 CF674933 CF674934 CF674935 CF674936 CF674937 CF674938 CZ482228 CZ482229 Entrez Gene - A searchable database of RefSeq genes. • 46187 UniProtKB/TrEMBL • B7Z0C1 Q9VRM3
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • PC00127
Linkouts
	BioGRID - A database of protein and genetic interactions • 70122 DroID - A comprehensive database of gene and protein interactions. • FBgn0010894 DRSC - Results from RNAi screens. • FBgn0010894 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0010894 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10624-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0010894 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 46187 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 46187 modMine - Data generated by the modENCODE project. • FBgn0010894
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	6524 (Harvie et al., 1998) CG10624 (Kim et al., 2004, Battersby et al., 2003, Easow et al., 2007, Ni et al., 2010.12.1) i8 (Battersby et al., 2003) l(3)06524 (Beitel and Krasnow, 2000, Spradling et al., 1999, Spradling et al., 1995, BDGP Project Members, 1994-1999, ) sinu (Sun et al., 2012, Christensen et al., 2008.7.11, Stork et al., 2008, Tonning et al., 2005, Christensen et al., 2007.10.29, Christensen et al., 2007.10.29, Wu et al., 2007, Hong et al., 2009, Yi et al., 2008, Wang et al., 2008, Nelson et al., 2010, Kertesz et al., 2007) Sinu (Furuse and Tsukita, 2006, Jane et al., 2005, Tian and Ten Hagen, 2007, Laprise et al., 2010, Nilton et al., 2010)
Name Synonym	sinuous (Beitel and Krasnow, 2000, Yi et al., 2008, Stork et al., 2008, Tiklova et al., 2010) Sinuous (Wu et al., 2007, Laprise et al., 2010, Nelson et al., 2010, Nilton et al., 2010)
Secondary FlyBase IDs
	FBgn0035613
References ( 64 )
Generate a list of	All references relating to this gene ( 64 )
List References by type	Research paper  ( 23 ) Supplementary material  ( 5 ) Review  ( 5 ) Personal communication to FlyBase  ( 14 ) Abstract  ( 3 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 11 ) Website  ( 1 )
Recent research papers ( 2 )
	Sun et al., 2012, PLoS Genet. 8(2): e1002515 Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants. [FBrf0217508] Oshima and Fehon, 2011, J. Cell Sci. 124(16): 2861--2871 Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large. [FBrf0214577] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...