Gene model reviewed during 5.46
Gene model reviewed during 5.55
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sinu using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\sinu in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The predicted gene structure and sequence of the release 3.1 annotation for sinu is based on an aberrantly spliced cDNA which has a novel and probably irrelevant C-terminal sequence. The correct structure and sequence for sinu gene product is given by the representative cDNA with accession number AY423544.
sinu is required for septate junction organisation and paracellular barrier formation.
Mutation in sinu alters tracheal tube size in embryos without affecting other aspects of tracheal development including primary branch budding and outgrowth or branch fusion.
Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.