RNA binding motif protein - controls germ-line stem cell self-renewal by repressing a differentiation pathway, possibly through regulating translation - RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
395 (aa); 49 (kD observed); 44 (kD predicted)
The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity (Potential).
The PGF motif may be involved in the interaction with HBS1 and is required for silencing of germline transposons.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pelo using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\pelo in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.