ms(2)21D, Heat shock protein 60 related, Hsp64
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Hsp60B using the Feature Mapper tool.
Hsp60B protein is localized in striated muscles surrounding the egg chamber, and in oviduct muscles; and in follicle cells, nurse cells, and oocytes. Hsp60B protein is specifically localized to the A bands of striated muscles that enwrap the ovariole and individual egg chambers, and the striated muscles of the oviduct. Hsp60B protein localizes to the external face of follicle cells. At oogenesis stage S10-11, Hsp60B protein is present in nurse cell cytoplasm, where it overlaps the distribution of F-actin, particularly near the cell membrane. It also appears to colocalize with the actin skeleton surrounding the nuclei of nurse cells. Less expression is observed in oocytes. After oogenesis stage 13, Hsp60B is largely absent from oocytes, and in nurse cells is concentrated in a small region of the nurse cell-oocyte junction that will form the micropyle of the mature oocyte.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Hsp60B in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.