OS-F, Pbprp3, 83a, DmelObp83a
Please see the JBrowse view of Dmel\Obp83a for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
Gene model reviewed during 5.55
0.89 (northern blot)
154 (aa); 17.3 (kD)
154 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Obp83a using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Expressed in antennal basiconic sensillum ab1-3 and 7 and in sensillum trichodeum. Observed in tormogen cells. Probably also present in trichogen cells but wasn't directly demonstrated.
Transcripts are detected in RNA from antennae but not in RNA from chemosensory depleted heads or bodies. In situ hybridization reveals that expression is limited to the ventro-lateral region of the third antennal segment, in a pattern consistent with the distribution of sensilla trichodea. In deeper sections, expression is observed beneath sensilla trichodea sensory hairs.
Obp83a transcripts are detected in RNA made from appendages but not head or body. By in situ hybridization, they are observed on the anterior surface of the third antennal segment and appear to be expressed in a subset of sensillum trichodea.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Obp83a in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day. Shows alteration in expression in a Clk mutant background.
Os-E and Pbprp3 are located about 1kb apart and contain a similar exon-intron organisation. Expression of both proteins is restricted spatially to two distinct types of olfactory hairs located in the ventrolateral region of the antenna. Immunocytochemical EM studies reveal that all sensilla examined express both proteins, thus, an individual sensilla can contain more than one odorant-binding protein.
Isolated from a subtracted antennal cDNA library enriched for cDNAs expressed in the antennae but not the rest of the head or body of adult flies.
A Pbprp3 cDNA has been cloned and sequenced.
Pbprp3 is one of seven clones that have been identified from subtracted cDNA libraries, containing antennal cDNA from which head cDNAs have been subtracted. Pbprp1 protein has sequences similar to those of Moth Pheromone-binding proteins (PBPs). Members of the PBP-related family are expressed in different subsets of sensilla.
Source for identity of: Obp83a Pbprp3
'Pbprp3' renamed to 'Obp83a' to rationalize the nomenclature of 'Odorant-binding protein'-encoding genes consistent with the recommendations in FBrf0151704 and FBrf0205523.
