• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\RpS4

General Information
Symbol	Dmel\RpS4	Species	D. melanogaster
Name	Ribosomal protein S4	Annotation symbol	CG11276
Feature type	protein_coding_gene	FlyBase ID	FBgn0011284
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	69F6-69F6	Sequence location	3L:13,034,856..13,037,012 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ribosomal protein S4 is referred to in FlyBase by the symbol Dmel\RpS4 (CG11276, FBgn0011284). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process: centrosome organization; mitotic spindle elongation; mitotic spindle organization; centrosome duplication. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: KOW; RNA-binding S4; Ribosomal protein S4e; Ribosomal protein S4e, N-terminal; Ribosomal protein S4e, N-terminal, conserved site; Ribosomal protein S4e, central. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1639949_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of RpS4. Gene sequence location is 3L:13034856..13037012.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood References Alonso and Santaren, 2006, J. Proteome Res. 5(8): 2025--2032
FB2012_01	References Müller et al., 2010, EMBO J. 29(19): 3344--3357 Sequence features HFA11272 BKN28912 Controlled Vocabulary Terms centrosome organization centrosome duplication
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 69F6-69F6   Limits computationally determined from genome sequence between P{lacW}RpS12s2783 and P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6
Experimentally Determined Cytological Location
Cytogenetic map Notes References   cDNA clone hybridises to two sites: 1B1-1B2 and 3A3-3A6. Sequence analysis is required to assign RpS4 to either site.   (Yokokura et al., 1993)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RpS4 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RpS4-RA FBtr0075884  NM_168537   983   261 RpS4-RB FBtr0075885  NM_079329   969   261
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RpS4-PA   FBpp0075618   29.1   261   10.85     NP_729871   AAF49847 RpS4-PB   FBpp0075619   29.1   261   10.85     NP_524053   AAF49846
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S4e, N-terminal, conserved site (IPR018199) Ribosomal protein S4e (IPR000876) RNA-binding S4 (IPR002942) KOW (IPR005824) Ribosomal protein S4e, N-terminal (IPR013843) Ribosomal protein S4e, central (IPR013845)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141945   AA202188   AA202386   AA263597   AA264007   AA390500   AA390749   AA391014   AA391034   AA391353   AA392199   AA439044   AA439715   AA439787   AA439837   AA538603   AA539510   AA694843   AA695228   AA695418   AA695451   AA695794   AA695957   AA696625   AA696725   AA697026   AA735688   AA802430   AA802432   AA802535   AA802536   AA802815   AA802989   AA803293   AA803654   AA803662   AA803711   AA803800   AA816906   AA817060   AA817157   AA817356   AA817388   AA820451   AA821081   AA821202   AA940827   AA940844   AA941262   AA941808   AA941900   AA941994   AA942259   AA942384   AA942414   AA949393   AA949423   AA949929   AA950596   AA950652   AA951121   AA951928   AE014296 AAF49846   AE014296 AAF49847   AF083546   AI062326   AI064372   AI064506   AI064558   AI064635   AI107559   AI109878   AI110059   AI134903   AI135140   AI135683   AI237992   AI238280   AI238695   AI256885   AI257380   AI257462   AI257654   AI257989   AI258378   AI258733   AI259357   AI259744   AI259898   AI260202   AI260282   AI260470   AI293164   AI293193   AI293449   AI294489   AI294820   AI294836   AI295056   AI295287   AI296082   AI296608   AI296649   AI296661   AI297332   AI297924   AI386724   AI387051   AI387340   AI387370   AI388018   AI388304   AI388312   AI388497   AI388986   AI389370   AI402678   AI403548   AI403950   AI404060   AI404114   AI404506   AI405394   AI455638   AI456415   AI456417   AI456641   AI456665   AI511619   AI512122   AI512419   AI512621   AI513370   AI513571   AI514304   AI514355   AI514682   AI514733   AI515133   AI515252   AI515588   AI515640   AI516031   AI516673   AI516975   AI517167   AI517809   AI518199   AI518786   AI518905   AI519512   AI520089   AI520407   AI532091   AI532533   AI534004   AI534008   AI534058   AI534802   AI542425   AI542987   AI543430   AX093923   AY231807   AY439895   BE978251   BG632323   BG632477   BG632661   BG633322   BG635521   BG636174   BG636369   BG636396   BG636409   BG636426   BG636558   BG636654   BG636680   BG636727   BG636888   BG637114   BG637368   BG637466   BG637500   BG639116   BG640088   BG640212   BG640262   BG640683   BG640923   BG641083   BG641171   BG641227   BG641244   BI141813   BI141843   BI142069   BI142194   BI161779   BI162403   BI164210   BI165374   BI166024   BI166321   BI166572   BI166975   BI167760   BI167865   BI167966   BI168784   BI168889   BI170060   BI170532   BI170552   BI170688   BI170920   BI171040   BI171169   BI171209   BI171280   BI171452   BI171483   BI171722   BI172191   BI172203   BI172498   BI172700   BI172800   BI173154   BI173275   BI173513   BI173692   BI212301   BI212459   BI213116   BI213691   BI214647   BI215100   BI215639   BI215804   BI216593   BI227627   BI227796   BI227990   BI228265   BI228280   BI228327   BI228738   BI229042   BI229083   BI229503   BI230126   BI230593   BI230841   BI231241   BI231729   BI233060   BI233218   BI234124   BI234209   BI235667   BI235826   BI235874   BI236092   BI236334   BI236621   BI236690   BI237333   BI237658   BI237886   BI237899   BI238387   BI238445   BI238464   BI238505   BI238889   BI239164   BI239303   BI240244   BI240301   BI240857   BI241110   BI241609   BI242259   BI242677   BI242756   BI242965   BI243848   BI352247   BI352271   BI352336   BI352421   BI352428   BI352534   BI352863   BI352879   BI352922   BI352932   BI352958   BI353070   BI353336   BI353383   BI353438   BI354029   BI354173   BI354176   BI354469   BI354495   BI354605   BI355026   BI355113   BI355312   BI355599   BI355617   BI355712   BI355970   BI356546   BI357261   BI358276   BI358342   BI361931   BI361963   BI362007   BI362979   BI363526   BI363770   BI363998   BI364070   BI364898   BI365260   BI365337   BI365613   BI366066   BI366157   BI366160   BI366291   BI366315   BI367371   BI367419   BI367591   BI367711   BI369278   BI369473   BI370630   BI370670   BI371267   BI371416   BI372708   BI372956   BI373234   BI373666   BI374088   BI375069   BI481605   BI481851   BI482849   BI483675   BI484132   BI484571   BI485206   BI486479   BI563521   BI563605   BI563907   BI564172   BI564238   BI564248   BI564436   BI564504   BI564559   BI564988   BI565432   BI566641   BI566832   BI566842   BI566856   BI567469   BI568074   BI568233   BI568466   BI569202   BI569514   BI569778   BI569789   BI569962   BI570264   BI570336   BI570454   BI570561   BI571136   BI571256   BI571357   BI571795   BI572028   BI572038   BI572814   BI572970   BI573545   BI574244   BI574262   BI574350   BI574400   BI574415   BI574466   BI574469   BI574634   BI574664   BI574884   BI575153   BI575170   BI575187   BI575933   BI576286   BI576369   BI576430   BI577012   BI577043   BI577062   BI577133   BI578118   BI579392   BI581441   BI581444   BI582101   BI582108   BI582560   BI582949   BI583625   BI583682   BI583785   BI584020   BI584189   BI584223   BI584614   BI585180   BI585386   BI585423   BI585569   BI585607   BI585631   BI585936   BI586413   BI586446   BI586455   BI586654   BI587049   BI587108   BI587188   BI587423   BI587479   BI587961   BI587962   BI588032   BI588073   BI588814   BI589004   BI589058   BI589210   BI589328   BI589371   BI589392   BI589648   BI589729   BI590232   BI590325   BI590345   BI590470   BI590535   BI590738   BI591448   BI591483   BI591516   BI591661   BI592144   BI592505   BI592895   BI593485   BI604387   BI605005   BI605212   BI605260   BI605481   BI605963   BI606202   BI606447   BI606868   BI606959   BI607354   BI607884   BI607899   BI608394   BI608426   BI608469   BI608868   BI609397   BI609940   BI610007   BI610050   BI610149   BI610539   BI610781   BI611174   BI611414   BI611489   BI611605   BI612136   BI612176   BI612921   BI613488   BI613535   BI614258   BI614718   BI614947   BI614949   BI615014   BI615090   BI615527   BI615824   BI616201   BI616373   BI616381   BI616546   BI616691   BI616963   BI617034   BI617672   BI617711   BI617787   BI618219   BI618863   BI619271   BI619287   BI619304   BI619562   BI619985   BI620429   BI620811   BI621323   BI621462   BI621942   BI622100   BI622119   BI622337   BI622741   BI623291   BI623378   BI623602   BI623957   BI624357   BI624692   BI624961   BI624996   BI625043   BI625699   BI626479   BI626510   BI626607   BI626668   BI626719   BI626942   BI627008   BI627062   BI627084   BI627243   BI627398   BI627757   BI627785   BI628254   BI628514   BI629002   BI629063   BI629092   BI629510   BI630381   BI630567   BI631374   BI631525   BI632523   BI632669   BI632844   BI632923   BI633050   BI633184   BI633213   BI633513   BI633598   BI633925   BI633950   BI633979   BI633984   BI635474   BI635602   BI635651   BI635811   BI635953   BI636345   BI636523   BI636615   BI636996   BI636999   BI637653   BI637800   BI638120   BI638270   BI638289   BI638558   BI638589   BI638684   BI638718   BI639291   BI639375   BI639437   BI639809   BI639863   BI640055   BI640163   BI640263   BI640399   BI640658   BI640756   BI640763   BI641032   BI641072   BI641504   BI641577   BP540370   BP542281   BP542329   BP542380   BP543758   BP544153   BP544255   BP544625   BP544972   BP545725   BP545970   BP546029   BP546242   BP546408   BP546434   BP546505   BP546591   BP547019   BP547116   BP547898   BP547993   BP548273   BP548522   BP548590   BP549153   BP549154   BP549489   BP550003   BP550004   BP550792   BP550837   BP550838   BP551129   BP551759   BP552240   BP552428   BP552578   BP552646   BP552792   BP553464   BP553604   BP553769   BP553785   BP553983   BP554166   BP555109   BP555294   BP555543   BP557303   BP557358   BP557669   BP557867   BP558136   BP558160   BP558203   BP558278   BP558419   BP558605   BP559682   BQ102850   BQ102910   BQ103089   BQ103333   BT011369   BX005868   BX006314   BX007043   BX010683   BX011296   BX012327   BX012934   BX013247   BX014099   BX015330   BX015462   BX015668   BX015680   BX016120   BX016595   BX018312   BX018786   BX018913   BX020639   BX021195   BX021883   BX025003   BX026066   BX028480   BX029062   BX029491   BX029593   BX029697   BX030245   BX030570   BX030722   BX031556   BX031735   BX032909   BX033133   BX033471   BX033575   BX035117   BX035832   BX036128   BX036298   BX036375   BX037066   BX039961   BX039993   BX041396   BX042028   BX042250   BX042474   BX042794   BX043010   BX043139   BX043140   BX043277   BX043654   BX043869   BX044234   BX044406   BX044593   BX044755   BX044895   BX045287   BX045874   BX046169   BX046425   BX046942   BX047568   BX047577   BX048232   BX048439   BX048932   BX049029   BX049041   BX049386   BX049407   BX049485   BX049660   BX049702   BX049752   BX049759   BX049891   BX050105   BX050206   BX050234   BX050747   BX050771   BX050823   BX050856   BX051236   BX051456   BX051727   BX051822   BX052186   BX052190   BX052287   BX052647   BX052711   BX052719   BX052773   BX052802   BX053006   BX053016   BX053090   BX053681   BX053740   BX054067   BX054206   BX054214   BX054804   BX054861   BX054863   BX054963   BX055075   BX055455   BX055575   BX055731   BX055831   BX055979   BX056064   BX056202   BX056257   BX056375   BX056377   BX056820   BX056966   BX056984   BX057088   BX057198   BX057911   BX058126   BX059036   BX059208   BX059529   BX059629   BX060477   BX060753   BX061634   BX061709   BX061823   BX061825   BX062080   BX062095   BX062106   BX062364   BX062700   BX062747   BX062785   BX063436   BX063804   BX063878   BX063987   BX064138   BX064206   BX064512   BX064794   BX064889   BX065095   BX065261   BX065537   BX065582   BX065954   BX066026   BX066428   BX066539   BX066625   BX066761   BX066763   BX066970   BX067061   BX067141   BX067398   BX067406   BX067612   BX068053   BX068084   BX068427   BX068532   BX068615   BX068970   BX069204   BX069287   BX069318   BX069660   BX069781   BX070356   BX070362   BX070469   BX070553   BX071167   BX071310   BX071516   BX071564   CA803254   CA803494   CA804287   CA804473   CA804550   CA804910   CA805220   CA805739   CA806036   CA806070   CA806447   CA806595   CA806670   CA807390   CA807532   CK131495   CK131496   CK135903   CK657185   CK659653   CK659763   CK660042   CK660360   CK660951   CK661035   CK661069   CK661214   CK661917   CK662317   CO153093   CO153210   CO153302   CO153673   CO153826   CO153947   CO154495   CO155547   CO156278   CO156403   CO156515   CO156904   CO156939   CO180119   CO182962   CO192601   CO193931   CO194484   CO194957   CO267761   CO273436   CO281560   CO284821   CO291627   CO294018   CO335663   CO336024   CO336491   CO337303   CO337374   CO337499   CO337821   CO337970   CO338415   CR938366   CR938380   CR938407   D16257 BAA03786   DQ440018   DQ675536   EC053344   EC061736   EC071965   EC086465   EC199464   EC236904   EC245702   EC260827   EC260974   EC261167   EC261291   EC261449   EC262247   EC262255   EC262723   EC263722   EC264142   EC264872   EC265846   EC265848   EC267004   EC267047   EC267904   EC268013   EF541363   EL883707   EL883813   EV575301   EV576847   EV578848   EV579114   EV579416   EV579683   EV579920   EV580020   EV580550   EV580579   EV583239   EV583255   EV583546   EV583712   EV585169   EV585319   EV586543   EV586813   EV587181   EV587917   EV588850   EV590333   EV590835   EV591306   EV591370   EV593181   EV593912   EV593990   EV595852   EV595984   EV596429   EV596845   EV596915   EV597089   EV597285   EV598652   EV599568   EV599603   EV600434   GH739764   GH740187   GH740802   GH741266   GH741300   GH742724   GH742846   GH743341   GH744006   GH744041   GH744918   GH745163   GH745522   GH762108   GH763272   GH764966   GH766307   GH767184   GH769407   GH779258
UniProtKB/Swiss-Prot	P41042
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0011284    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0011284 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0011284 expression level Developmental Stage   Expression Level embryo 00-02hr    146584 embryo 02-04hr    210946 embryo 04-06hr    232010 embryo 06-08hr    235085 embryo 08-10hr    252743 embryo 10-12hr    270972 embryo 12-14hr    188472 embryo 14-16hr    270290 embryo 16-18hr    216046 embryo 18-20hr    219568 embryo 20-22hr    209944 embryo 22-24hr    194637 larva L1    319703 larva L2    238095 larva L3 12hr old    177225 larva L3 puffstage 1-2    128914 larva L3 puffstage 3-6    121936 larva L3 puffstage 7-9    140358 white prepupae new    125557 white prepupae 12hr    104622 white prepupae 24hr    99224 pupae 2d postWPP    92409 pupae 3d postWPP    79497 pupae 4d postWPP    99463 adult male 01day    67717 adult male 05day    65165 adult male 30day    83449 adult female 01day    187088 adult female 05day    158536 adult female 30day    167013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    146584 embryo 02-04hr    210946 embryo 04-06hr    232010 embryo 06-08hr    235085 embryo 08-10hr    252743 embryo 10-12hr    270972 embryo 12-14hr    188472 embryo 14-16hr    270290 embryo 16-18hr    216046 embryo 18-20hr    219568 embryo 20-22hr    209944 embryo 22-24hr    194637 larva L1    319703 larva L2    238095 larva L3 12hr old    177225 larva L3 puffstage 1-2    128914 larva L3 puffstage 3-6    121936 larva L3 puffstage 7-9    140358 white prepupae new    125557 white prepupae 12hr    104622 white prepupae 24hr    99224 pupae 2d postWPP    92409 pupae 3d postWPP    79497 pupae 4d postWPP    99463 adult male 01day    67717 adult male 05day    65165 adult male 30day    83449 adult female 01day    187088 adult female 05day    158536 adult female 30day    167013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0011284 expression level Developmental Stage   Expression Level embryo 00-02hr    146584 embryo 02-04hr    210946 embryo 04-06hr    232010 embryo 06-08hr    235085 embryo 08-10hr    252743 embryo 10-12hr    270972 embryo 12-14hr    188472 embryo 14-16hr    270290 embryo 16-18hr    216046 embryo 18-20hr    219568 embryo 20-22hr    209944 embryo 22-24hr    194637 larva L1    319703 larva L2    238095 larva L3 12hr old    177225 larva L3 puffstage 1-2    128914 larva L3 puffstage 3-6    121936 larva L3 puffstage 7-9    140358 white prepupae new    125557 white prepupae 12hr    104622 white prepupae 24hr    99224 pupae 2d postWPP    92409 pupae 3d postWPP    79497 pupae 4d postWPP    99463 adult male 01day    67717 adult male 05day    65165 adult male 30day    83449 adult female 01day    187088 adult female 05day    158536 adult female 30day    167013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (146584) embryo 02-04hr  (210946) embryo 04-06hr  (232010) embryo 06-08hr  (235085) embryo 08-10hr  (252743) embryo 10-12hr  (270972) embryo 12-14hr  (188472) embryo 14-16hr  (270290) embryo 16-18hr  (216046) embryo 18-20hr  (219568) embryo 20-22hr  (209944) embryo 22-24hr  (194637) larva L1  (319703) larva L2  (238095) larva L3 12hr old  (177225) larva L3 puffstage 1-2  (128914) larva L3 puffstage 3-6  (121936) larva L3 puffstage 7-9  (140358) white prepupae new  (125557) white prepupae 12hr  (104622) white prepupae 24hr  (99224) pupae 2d postWPP  (92409) pupae 3d postWPP  (79497) pupae 4d postWPP  (99463) adult male 01day  (67717) adult male 05day  (65165) adult male 30day  (83449) adult female 01day  (187088) adult female 05day  (158536) adult female 30day  (167013) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    146584 embryo 02-04hr    210946 embryo 04-06hr    232010 embryo 06-08hr    235085 embryo 08-10hr    252743 embryo 10-12hr    270972 embryo 12-14hr    188472 embryo 14-16hr    270290 embryo 16-18hr    216046 embryo 18-20hr    219568 embryo 20-22hr    209944 embryo 22-24hr    194637 larva L1    319703 larva L2    238095 larva L3 12hr old    177225 larva L3 puffstage 1-2    128914 larva L3 puffstage 3-6    121936 larva L3 puffstage 7-9    140358 white prepupae new    125557 white prepupae 12hr    104622 white prepupae 24hr    99224 pupae 2d postWPP    92409 pupae 3d postWPP    79497 pupae 4d postWPP    99463 adult male 01day    67717 adult male 05day    65165 adult male 30day    83449 adult female 01day    187088 adult female 05day    158536 adult female 30day    167013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0011284    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0011284 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0011284 expression level Tissue   Expression Level Larval Central Nervous System    2569.175 Larval Midgut    4324.1 Larval Hindgut    3994.4 Larval Malpighian Tubules    4502.3 Larval Fat Body    7058.9 Larval Salivary Gland    7207.2 Larval Trachea    5662.725 Larval Carcass    4237.225 Adult Head    4116.6 Adult Eye    5576.875 Adult Brain    2727.7 Adult Thoracic-Abdominal Ganglion    3964.6 Adult Crop    5228.4 Adult Midgut    4554 Adult Hindgut    4418.8 Adult Malpighian Tubules    4464.3 Adult Fat Body    5143.5 Adult Salivary Gland    10251.4 Adult Heart    5988.05 Adult VirginFemale Spermatheca    5346.1 Adult InseminatedFemale Spermatheca    5556.3 Adult Ovary    3209.2 Adult Testis    895.7 Adult Male Accessory Gland    8628.8 Adult Carcass    5568.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2569.175) Larval Midgut  (4324.1) Larval Hindgut  (3994.4) Larval Malpighian Tubules  (4502.3) Larval Fat Body  (7058.9) Larval Salivary Gland  (7207.2) Larval Trachea  (5662.725) Larval Carcass  (4237.225) Adult Head  (4116.6) Adult Eye  (5576.875) Adult Brain  (2727.7) Adult Thoracic-Abdominal Ganglion  (3964.6) Adult Crop  (5228.4) Adult Midgut  (4554) Adult Hindgut  (4418.8) Adult Malpighian Tubules  (4464.3) Adult Fat Body  (5143.5) Adult Salivary Gland  (10251.4) Adult Heart  (5988.05) Adult VirginFemale Spermatheca  (5346.1) Adult InseminatedFemale Spermatheca  (5556.3) Adult Ovary  (3209.2) Adult Testis  (895.7) Adult Male Accessory Gland  (8628.8) Adult Carcass  (5568.1) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2569.175) Larval Midgut  (4324.1) Larval Hindgut  (3994.4) Larval Malpighian Tubules  (4502.3) Larval Fat Body  (7058.9) Larval Salivary Gland  (7207.2) Larval Trachea  (5662.725) Larval Carcass  (4237.225) Adult Head  (4116.6) Adult Eye  (5576.875) Adult Brain  (2727.7) Adult Thoracic-Abdominal Ganglion  (3964.6) Adult Crop  (5228.4) Adult Midgut  (4554) Adult Hindgut  (4418.8) Adult Malpighian Tubules  (4464.3) Adult Fat Body  (5143.5) Adult Salivary Gland  (10251.4) Adult Heart  (5988.05) Adult VirginFemale Spermatheca  (5346.1) Adult InseminatedFemale Spermatheca  (5556.3) Adult Ovary  (3209.2) Adult Testis    895.7 Adult Male Accessory Gland  (8628.8) Adult Carcass  (5568.1) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2569.175 Larval Midgut    4324.1 Larval Hindgut    3994.4 Larval Malpighian Tubules    4502.3 Larval Fat Body    7058.9 Larval Salivary Gland    7207.2 Larval Trachea    5662.725 Larval Carcass    4237.225 Adult Head    4116.6 Adult Eye    5576.875 Adult Brain    2727.7 Adult Thoracic-Abdominal Ganglion    3964.6 Adult Crop    5228.4 Adult Midgut    4554 Adult Hindgut    4418.8 Adult Malpighian Tubules    4464.3 Adult Fat Body    5143.5 Adult Salivary Gland    10251.4 Adult Heart    5988.05 Adult VirginFemale Spermatheca    5346.1 Adult InseminatedFemale Spermatheca    5556.3 Adult Ovary    3209.2 Adult Testis    895.7 Adult Male Accessory Gland    8628.8 Adult Carcass    5568.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0011284 expression level Tissue   Expression Level Larval Central Nervous System    2569.175 Larval Midgut    4324.1 Larval Hindgut    3994.4 Larval Malpighian Tubules    4502.3 Larval Fat Body    7058.9 Larval Salivary Gland    7207.2 Larval Trachea    5662.725 Larval Carcass    4237.225 Adult Head    4116.6 Adult Eye    5576.875 Adult Brain    2727.7 Adult Thoracic-Abdominal Ganglion    3964.6 Adult Crop    5228.4 Adult Midgut    4554 Adult Hindgut    4418.8 Adult Malpighian Tubules    4464.3 Adult Fat Body    5143.5 Adult Salivary Gland    10251.4 Adult Heart    5988.05 Adult VirginFemale Spermatheca    5346.1 Adult InseminatedFemale Spermatheca    5556.3 Adult Ovary    3209.2 Adult Testis    895.7 Adult Male Accessory Gland    8628.8 Adult Carcass    5568.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (2569.175) Larval Midgut  (4324.1) Larval Hindgut  (3994.4) Larval Malpighian Tubules  (4502.3) Larval Fat Body  (7058.9) Larval Salivary Gland  (7207.2) Larval Trachea  (5662.725) Larval Carcass  (4237.225) Adult Head  (4116.6) Adult Eye  (5576.875) Adult Brain  (2727.7) Adult Thoracic-Abdominal Ganglion  (3964.6) Adult Crop  (5228.4) Adult Midgut  (4554) Adult Hindgut  (4418.8) Adult Malpighian Tubules  (4464.3) Adult Fat Body  (5143.5) Adult Salivary Gland  (10251.4) Adult Heart  (5988.05) Adult VirginFemale Spermatheca  (5346.1) Adult InseminatedFemale Spermatheca  (5556.3) Adult Ovary  (3209.2) Adult Testis  (895.7) Adult Male Accessory Gland  (8628.8) Adult Carcass  (5568.1) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (2569.175) Larval Midgut  (4324.1) Larval Hindgut  (3994.4) Larval Malpighian Tubules  (4502.3) Larval Fat Body  (7058.9) Larval Salivary Gland  (7207.2) Larval Trachea  (5662.725) Larval Carcass  (4237.225) Adult Head  (4116.6) Adult Eye  (5576.875) Adult Brain  (2727.7) Adult Thoracic-Abdominal Ganglion  (3964.6) Adult Crop  (5228.4) Adult Midgut  (4554) Adult Hindgut  (4418.8) Adult Malpighian Tubules  (4464.3) Adult Fat Body  (5143.5) Adult Salivary Gland  (10251.4) Adult Heart  (5988.05) Adult VirginFemale Spermatheca  (5346.1) Adult InseminatedFemale Spermatheca  (5556.3) Adult Ovary  (3209.2) Adult Testis    895.7 Adult Male Accessory Gland  (8628.8) Adult Carcass  (5568.1) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2569.175 Larval Midgut    4324.1 Larval Hindgut    3994.4 Larval Malpighian Tubules    4502.3 Larval Fat Body    7058.9 Larval Salivary Gland    7207.2 Larval Trachea    5662.725 Larval Carcass    4237.225 Adult Head    4116.6 Adult Eye    5576.875 Adult Brain    2727.7 Adult Thoracic-Abdominal Ganglion    3964.6 Adult Crop    5228.4 Adult Midgut    4554 Adult Hindgut    4418.8 Adult Malpighian Tubules    4464.3 Adult Fat Body    5143.5 Adult Salivary Gland    10251.4 Adult Heart    5988.05 Adult VirginFemale Spermatheca    5346.1 Adult InseminatedFemale Spermatheca    5556.3 Adult Ovary    3209.2 Adult Testis    895.7 Adult Male Accessory Gland    8628.8 Adult Carcass    5568.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    4116.6   NA  Eye    5576.875   NA  Brain    2727.7   2569.175  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3964.6   NA  Crop    5228.4   4324.1  Midgut    4554   3994.4  Hindgut    4418.8   4502.3  Malpighian Tubules    4464.3   7058.9  Fat Body    5143.5   7207.2  Salivary Gland    10251.4   NA  Heart    5988.05   5662.725  Trachea    NA   NA  VirginFemale Spermatheca    5346.1   NA  InseminatedFemale Spermatheca    5556.3   NA  Ovary    3209.2   NA  Testis    895.7   NA  Male Accessory Gland    8628.8   4237.225  Carcass    5568.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_22
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011284 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11276-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 RpS4GD13437 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of RpS4 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RpS4 Class Mutagen Stocks Known lesion RpS4GD13437 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes RpS4GD17217 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RpS4KK108912 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6261 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13437} NA P{GD17217} NA P{KK108912} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
centrosome duplication inferred from mutant phenotype (Müller et al., 2010) centrosome organization inferred from mutant phenotype (Müller et al., 2010) mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Cermelli et al., 2006) ribosome inferred from direct assay (Alonso and Santaren, 2006)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
RNA binding inferred from electronic annotation with InterPro:IPR002942 (FlyBase Curators et al., 2004-) structural constituent of ribosome inferred from sequence or structural similarity with Saccharomyces RPS4A (FlyBase, 1992-) non-traceable author statement (Yokokura, 1994.1.13, Swiss-Prot Project Members, 1995.2.1)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with Saccharomyces RPS4A (FlyBase, 1992-) non-traceable author statement (Yokokura, 1994.1.13)
Cellular Component
CV term Evidence References
cytosolic small ribosomal subunit inferred from sequence or structural similarity with Saccharomyces RPS4A (FlyBase, 1992-) non-traceable author statement (Yokokura, 1994.1.13) ribosome non-traceable author statement (Swiss-Prot Project Members, 1995.2.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RpS4 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64829 DroID - A comprehensive database of gene and protein interactions. • FBgn0011284 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39484
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24027 Dere\GG15623 Dgri\GH17143 Dmoj\GI11752 Dper\GL25330 Dpse\GA10883 Dsec\GM25394 Dsim\GD14426 Dvir\GJ13462 Dwil\GK17425 Dyak\RpS4
Curated drosophilid orthologs	Dpse\GA10883   Dyak\RpS4
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP006871-PA Anopheles gambiae (mosquito) XP_623050.1 Apis mellifera (honey bee) XP_001949785.1 Acyrthosiphon pisum (pea aphid) At2g17360.1 Arabidopsis thaliana (wall cress) At5g07090.1 Arabidopsis thaliana (wall cress) At5g58420.1 Arabidopsis thaliana (wall cress) 35382 Batrachochytrium dendrobatidis (chytrid fungus) 61784 Branchiostoma floridae (lancelet) 81739 Branchiostoma floridae (lancelet) XP_001892793.1 Brugia malayi (roundworm nematode) BGIBMGA010867-PA Bombyx mori (silk worm) ENSBTAP00000025024 Bos taurus (bovine) ENSBTAP00000052226 Bos taurus (bovine) CAL0004156 Candida albicans (a form of yeast) CAL0004310 Candida albicans (a form of yeast) CN11864 Caenorhabditis brenneri (small nematode) CBP01507 Caenorhabditis briggsae (nematode) CE24278 Caenorhabditis elegans (worm) ENSCAFP00000025264 Canis familiaris (dog) CAGL0F09031g Candida glabrata (haploid yeast) Chro.70527 Cryptosporidium hominis (obligate parasite) ENSCINP00000015550 Ciona intestinalis (sea squirt) JA12088 Caenorhabditis japonica (nematode) CMH218C Cyanidioschyzon merolae (red alga) cn01610 Cryptococcus neoformans (yeast-like fungus) cgd7_4760 Cryptosporidium parvum (protozoan parasite) CPIJ003013 Culex pipens (mosquito) ENSCPOP00000019511 Cavia porcellus (guinea pig) 188837 Chlamidomonas reinhardtii (green alga) RP32861 Caenorhabditis remanei (nematode) ENSCSAVP00000008862 Ciona savignyi (sedentary tunicate) 152725 Capitella spl (polychaete worm) DDB0185063 Dictyostelium discoideum (amoeba) DEHA2F03300g Debaryomyces Hansenii (yeast) DEHA2G07392g Debaryomyces Hansenii (yeast) 300650 Daphnia pulex (daphnia) ENSDARP00000014931 Danio rerio (zebra fish) ENSECAP00000008853 Equus caballus (horse) XP_648911 Entamoeba histolytica (anaerobic protozoan) XP_649211 Entamoeba histolytica (anaerobic protozoan) XP_656039 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000024775 Gymnopilus aculeatus (mushroom) ENSGALP00000039655 Gallus gallus (chicken) GL50803_11359 Giardia lamblia (flagellated protozoan) 185809 Hypsipyla robusta (cedar shoot borer) ENSP00000362744 Homo sapiens (human) ISCW024787-PA Ixodes scapularis (deer tick) KLLA0B03652g Kluyveromyces lactis (yeast) 210271 Lottia gigantea (owl limpet) LmjF13.1220 Leishmania major (virus) LmjF13.1230 Leishmania major (virus) 33368 Monocosta brevicollis (choanoflagellate) ENSMODP00000033654 Monodelphis domestica (gray opossum) ENSMMUP00000004386 Macaca mulatta (rhesus monkey) ENSMUSP00000033683 Mus musculus (house mouse) 173646 Nematostella vectensis (starlet anemone) XP_001599933.1 Nasonia vitripennis (wasp) ENSOANP00000004684 Ornithorynchus anatinus (platypus) ENSORLP00000012015 Oryzias latipes (japanese killifish) LOC_Os01g25610.1 Oryza sativa (asian rice) LOC_Os02g01560.1 Oryza sativa (asian rice) 29689 Ostreococcus tauri (green alga) PF11_0065 Plasmodium falciparum (protozoal parasite) PHUM000340-PA Pediculus humanus (human body louse) 197071 Physcomitrella patens (moss) ENSPPYP00000022909 Pongo pygmaeus (orangutan) 132408 Phytophthora sojae (root rot pathogen) 240413 Populus trichocarpa (black cottonwood) 257929 Populus trichocarpa (black cottonwood) 575195 Populus trichocarpa (black cottonwood) ENSPTRP00000037867 Pan troglodytes (chimpanzee) PVX_090950 Plasmodium vivax (protozoal parasite) ENSRNOP00000004278 Rattus norvegicus (norway rat) ENSRNOP00000043988 Rattus norvegicus (norway rat) 4751998 Sorghum bicolor (sorghum) YHR203C Saccharomyces cerevisiae (budding yeast) YJR145C Saccharomyces cerevisiae (budding yeast) Smp_011570.1 Schistosoma mansoni (trematode parasite) SPAC959.07 Schizosaccharomyces pombe (fission yeast) SPBC19F8.08 Schizosaccharomyces pombe (fission yeast) SPBC21B10.10 Schizosaccharomyces pombe (fission yeast) XP_001187213.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001192878.1 Strongylocentrotus purpuratus (purple sea urchin) 37748 Trichoplax adhaerens (metazoa) TA10515 Theileria annulata (apicomplexan parasite) XP_969262.1 Tribolium castaneum (red flour beetle) Tc00.1047053509683.117 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511051.39 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511051.50 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005439 Tetraodon nigroviridis (green spotted pufferfish) TP04_0680 Theileria parva (parasitic protozoan) 27292 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020259 Takifugu rubripes (pufferfish Takifugu) 3700.m00085 Tetrahymena thermophila (ciliate protozoa) 134327.m00011 Trichomonas vaginalis (parasitic flagellated protozoan) 83641.m00158 Trichomonas vaginalis (parasitic flagellated protozoan) 84561.m00143 Trichomonas vaginalis (parasitic flagellated protozoan) 88273.m00398 Trichomonas vaginalis (parasitic flagellated protozoan) 91860.m00077 Trichomonas vaginalis (parasitic flagellated protozoan) 93440.m00415 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000056754 Xenopus tropicalis (frog) YALI0D12903g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16758 NV11016 LH13539 RS4_IXOSC FBgn0068048 FBgn0219424 FBgn0200686 FBgn0186109 FBgn0180252 JGI_V11_304892 JGI_V11_300650 FBgn0070939 FBgn0162914 FBgn0134511 FBgn0124613 FBgn0107867 FBgn0101021 CPIJ003013 BGIBMGA010867 ACYPI000100 GB19305 AGAP006871 PHUM601190 GLEAN_13431
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
VDRC	v106654 P{KK108912}VIE-260B v35718 w1118; P{GD13437}v35718 v35720 w1118; P{GD13437}v35720 v50021 w1118; P{GD17217}v50021/CyO
Genomic Clones ( 1 )
	BACR08G07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 825 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE57333
Other clones	yak-em_RpS4
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH01489 GH02850 GH04758 GH05018 GH06551 GH09307 GH09509 GH12781 GH13930 GH14295 GH14786 GH17846 GH17881 GH18748 GH19154 GH19166 GH20053 GH20520 GH21942 GH23014 GH23649 GH23715 GH24247 GH24272 GH25380 GH27589 GH27817 GH28872 GM04481 GM05544 GM06356 GM06728 GM08030 GM13841 GM18514 GM18835 GM19206 GM19217 GM19684 GM21459 GM22103 GM23620 GM26014 GM26711 GM26938 GM27038 GM27586 GM29256 GM29545 GM31533 LD02294 LD02563 LD06940 LD07328 LD08713 LD09928 LD10216 LD11569 LD13479 LD14352 LD14448 LD14513 LD20094 LD22077 LD22616 LD23079 LD23106 LD24087 LD26367 LD26554 LD26615 LD28274 LD28320 LD28495 LD30454 LD30558 LD32839 LD35168 LD36238 LD36432 LD36434 LD36730 LD36762 LD39130 LD40048 LD40558 LD41234 LD42635 LD43847 LD44291 LD46832 LD46991 LD47474 LP01561 LP01995 LP02750 LP03231 LP03419 LP03913 LP04023 LP04347 LP05725 LP06074 LP06330 LP06331 LP06516 LP07871 LP08281 LP08303 LP08576 LP09891 LP10567 LP10620 LP10640 LP11610 LP12371 LP17562 LP17756 LP18264 LP18870 LP19943 LP20117 LP20176 LP20460 LP22419 LP23280 RE41642 SD03458 SD04072 SD08748 SD10174 SD11036 SD11180 SD11239 SD11822 SD12326 SD12445 SD12691 SD14039 SD14094 SD14295 SD14441 SD14504 SD14707 SD14974 SD15475 SD15524 SD16066 SD16840 SD16994 SD17064 SD17502 SD18356 SD18868 SD18872 SD19712 SD19884 SD20331 SD20517 SD20540 SD20871 SD21038 SD21078 SD21841 SD21942 SD22012 SD22494 SD22560 SD22823 SD22965 SD23076 SD23616 SD23750 SD24091 SD24857 SD24972 SD26324 SD27019 SD27192 SD27239 SD28210
Other clones	10836 38709 42714 52334 70368 103665 522048 522682 522978 523756 525780 528001 533447 533489 533838 542548 542602 556913 557911 568950 569172 569667 571379 bs75h11 CK00046 Dmel_dig_000390_0690_3631 Dmel_dig_002049_0648_0523 Dmel_dig_004523_0628_1614 Dmel_dig_006185_0588_2412 Dmel_dig_006962_0674_0568 Dmel_dig_008139_0633_2504 Dmel_dig_008499_0595_1101 Dmel_dig_010310_0593_0765 Dmel_dig_012329_0687_0772 Dmel_dig_012746_0716_0896 Dmel_dig_013332_0650_2835 Dmel_dig_015247_0664_2070 Dmel_dig_016611_0633_3392 Dmel_dig_016764_0660_1170 Dmel_dig_017034_0631_2103 Dmel_dig_018416_0631_2485 Dmel_neb_002148_0361_0599 Dmel_neb_005905_0161_0358 Dmel_neb_007381_0184_2207 Dmel_neb_009015_0690_1908 Dmel_neb_009444_0382_1234 Dmel_neb_010531_0414_3434 Dmel_neb_010679_0110_3004 Dmel_neb_010881_0097_0598 Dmel_neb_011549_0846_2894 Dmel_neb_011975_0604_1382 Dmel_neb_012107_0641_1667 Dmel_neb_012176_0619_3467 Dmel_neb_012872_0838_2115 Dmel_neb_013347_0676_2831 Dmel_neb_013727_0936_2882 Dmel_neb_013827_0882_1113 Dmel_neb_015058_0902_3331 Dmel_neb_015219_0367_1523 Dmel_neb_015259_0144_1851 Dmel_neb_015422_0954_0851 Dmel_neb_015638_0929_2151 Dmel_neb_015787_0851_2945 Dmel_neb_016040_0839_2748 EC00945 EC24346 EC34131 EC37110 EC38649 EC39519 EC053344 EK110945 EK151758 EK157439 EK166913 EK197838 EK205504 EN01250 EN01508 EN01709 EN02547 EN02909 EN03152 EN04237 EN06309 EN07722 EN08009 EN08221 EN09532 EN09619 EN10938 EN11657 EN12636 EN14235 EN14405 EN14654 EN15349 EN15704 EN16738 ESG011b.E7_C03 ESG011b.E21_C03 ESG013b.E21_G12 ESG014a.E21_E03 ESG014c.E21_A11 ESG017c.E21.3_H10 ESG018b.E21.1_F10 ESG0112d.B21_G11 ESG0113d.B21_A06 ESG0114a.B21_F09 ESG0115d.B21_A08 ESG0117a.B21_E03 ESG0119c.B21_A10 ESG0120d.B21_B04 ESG0120d.B21_F05 FGA002G01 FGC011B08 FGC011H11 FGC012E06 FGC022C01 FGC024D02 FGC024H06 FGC026H06 FGC028G10 FGC032H05 FGH101E01 FGH102A12 FGH104C11 FGH106B02 FGH106D04 FGH107B05 FGH108A07 FGH112E10 FGH113F01 FGH121H03 FGH122H05 FGH125H02 FGH128F09 FGH129D07 FGM004A01 FGM101G07 FGM104G03 FGM209B06 FGM209D11 FGM211B01 FGM214F05 FGM217F05 FGM218F12 FGM219E11 FGM220A01 FGM220G10 FGM224E10 FGM225C09 FGM226B11 FGM226C07 FGM227D03 FGM228D04 FGM233E04 FGM234E04 FGM235H01 FGM308E10 FGM308H02 FGM310E10 FGM311F08 FGM313B11 FGM313C12 FGM313F04 FGM314A11 FGM314H04 FGM316A01 FGM322C08 GH04955 GH05303 GH09262 GH12062 GH12480 GH13521 GH16272 GH16310 GH16908 GH17476 GH19434 GH23507 GH26550 GH26704 GM01656 GM02447 GM02792 GM02845 GM04830 GM05546 GM05779 GM05781 GM08258 GM08956 GM09507 GM09624 GM10523 GM13813 GM14066 GM14311 GM14861 GM14913 GM18606 GM21110 GM21151 GM21296 GM21333 GM23177 GM23383 GM26706 GM30355 GM31620 GM32069 IP13365 IP13465 LD08806 LD09976 LD17673 LD18170 LD22323 LD22654 LD25310 LD26018 LD27232 LD27371 LD31430 LD35768 LD37644 LD38524 LD40830 LD41169 LD41765 LD43087 LD43835 LD44542 LD47542 LP03572 LP05840 LP06596 LP08875 LP21724 RE01184 RE01732 RE03838 RE05255 RE06043 RE06410 RE06739 RE07237 RE08217 RE08349 RE08488 RE09648 RE09786 RE11407 RE12029 RE12058 RE12227 RE12546 RE12694 RE12868 RE12924 RE13014 RE13233 RE13272 RE13553 RE14305 RE14480 RE14494 RE15010 RE15291 RE15351 RE15477 RE15909 RE16063 RE16445 RE16772 RE17366 RE17555 RE18444 RE19148 RE20479 RE20621 RE21316 RE22213 RE22520 RE23350 RE23786 RE24730 RE25047 RE25387 RE25747 RE25768 RE25842 RE26375 RE26739 RE26787 RE27295 RE29336 RE29511 RE29768 RE29869 RE31572 RE31766 RE31824 RE32090 RE32375 RE32695 RE32784 RE33547 RE33923 RE34211 RE34231 RE34813 RE34916 RE34941 RE34986 RE35579 RE35760 RE36944 RE37041 RE37110 RE37792 RE38125 RE38724 RE39547 RE40074 RE40174 RE40474 RE42001 RE42723 RE43685 RE45001 RE45085 RE46352 RE46403 RE46457 RE47678 RE48356 RE48711 RE49014 RE49114 RE50091 RE50512 RE50611 RE50974 RE51510 RE51630 RE51634 RE51796 RE51825 RE53126 RE53181 RE53386 RE53519 RE55408 RE55658 RE57383 RE58127 RE58295 RE59751 RE60157 RE60479 RE61022 RE61605 RE62794 RE64183 RE64458 RE65625 RE66594 RE67177 RE67692 RE68494 RE69912 RE70776 RE71927 RE73419 RH01352 RH01605 RH01928 RH01940 RH02172 RH02556 RH02644 RH02790 RH03119 RH03207 RH03824 RH03930 RH03952 RH04093 RH04168 RH04402 RH05225 RH05264 RH05317 RH05958 RH06094 RH06210 RH06216 RH06523 RH07090 RH07363 RH07373 RH08456 RH08546 RH09145 RH09769 RH10214 RH10709 RH11560 RH11860 RH11885 RH12875 RH12954 RH13021 RH13579 RH14171 RH14792 RH14868 RH14919 RH15074 RH16039 RH16575 RH17326 RH17620 RH17801 RH17961 RH18876 RH18880 RH20018 RH20027 RH20808 RH21373 RH22282 RH22347 RH22473 RH22773 RH22993 RH23022 RH23177 RH23235 RH23284 RH23411 RH23434 RH23638 RH23651 RH23860 RH24657 RH24932 RH24989 RH25177 RH25226 RH25252 RH25641 RH25936 RH25974 RH26357 RH26393 RH26406 RH26733 RH27316 RH27376 RH27433 RH27678 RH28095 RH28164 RH28432 RH28455 RH28475 RH28901 RH28902 RH29035 RH29085 RH30249 RH30655 RH30731 RH31570 RH31740 RH32333 RH32819 RH32919 RH32987 RH33750 RH33805 RH33826 RH33908 RH33929 RH34167 RH34269 RH34650 RH35906 RH36110 RH36121 RH36344 RH36584 RH36601 RH36625 RH37869 RH39426 RH39640 RH40021 RH40541 RH40582 RH41925 RH42650 RH42703 RH43590 RH44170 RH44448 RH44452 RH44529 RH44630 RH45194 RH45657 RH46088 RH46305 RH46314 RH46532 RH46740 RH47148 RH47237 RH48079 RH48126 RH48225 RH48819 RH49792 RH50272 RH50291 RH50314 RH50622 RH51138 RH51574 RH52043 RH52646 RH52809 RH53734 RH53923 RH53942 RH54183 RH54654 RH55412 RH55611 RH55915 RH56325 RH56611 RH56940 RH57787 RH57867 RH57903 RH58387 RH59413 RH59837 RH60928 RH61114 RH61711 RH61803 RH61861 RH62593 RH63207 RH63907 RH64292 RH64737 RH64784 RH64853 RH66173 RH67435 RH67472 RH67604 RH67672 RH67747 RH68093 RH68183 RH68254 RH68284 RH68505 RH68693 RH69166 RH69217 RH69720 RH70517 RH70760 RH70837 RH71101 RH71990 RH72424 RH72927 RH73711 RH73934 RH74409 RP001013247 RP001013968 RP001014648 RP001015121 RP001015453 RP001016863 RP001022638 RP001030588 RP001030793 RP001032835 RP001036084 RP001037933 RP001039167 RP001042313 RP001046475 RP001046604 RP001047396 RP001047630 RP001051232 RP001051336 SD01028 SD06424 SD06432 SD06548 SD09530 SD12104 SD12517 SD12541 SD12957 SD13774 SD14118 SD14139 SD14410 SD15322 SD15741 SD15779 SD16208 SD17310 SD17990 SD18228 SD20920 SD23242 SD23757 SD24184 SD26503 SD26729 SD26826 SD27621 SD27727 SD28127 SD28165 SD28205
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011284 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39484
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	"RpS4" likely corresponds to "M(3)69E". (Marygold et al., 2007) It is not possible to say whether "M(3)69E" corresponds to "RpS12" or "RpS4", or whether the genetically-defined "M(3)69E" locus is a composite of both ribosomal protein genes. (Deal and Cook, 2002.1.22)
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short, monopolar spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Likely Minute gene. (Marygold et al., 2007) A deletion removing RpS4 and RpS12 shows Minute phenotypes, whereas deletions removing RpS12 but no other cytoplasmic ribosomal protein-encoding genes do not show Minute phenotypes, suggesting that RpS4 is a Minute gene. (Marygold et al., 2007) RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) Area matching Drosophila ribosomal S4 protein gene, Acc No. D16257. Probable intron. (Davies, 2001.3.15) RpS4 cDNA is cloned and sequenced, a high degree of sequence similarity with mammalian RpS4 proteins suggests the proteins are encoded by homologous genes that have very similar biochemical activities. (Yokokura et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079329 NM_168537 RefSeq (Proteins) • NP_524053 NP_729871 DDBJ / EMBL / GenBank • AAF49846 AAF49847 AF083546 AX093923 BAA03786 BI370630 D16257 Entrez Gene - A searchable database of RefSeq genes. • 39484 UniProtKB/Swiss-Prot • P41042
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribosomal protein S4e, N-terminal, conserved site (IPR018199) Ribosomal protein S4e (IPR000876) RNA-binding S4 (IPR002942) KOW (IPR005824) Ribosomal protein S4e, N-terminal (IPR013843) Ribosomal protein S4e, central (IPR013845)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64829 DroID - A comprehensive database of gene and protein interactions. • FBgn0011284 DRSC - Results from RNAi screens. • FBgn0011284 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011284 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11276-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011284 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39484 InParanoid A subset of ortholog calls from InParanoid. • AGAP006871-PA Anopheles gambiae (mosquito) XP_623050.1 Apis mellifera (honey bee) XP_001949785.1 Acyrthosiphon pisum (pea aphid) At2g17360.1 Arabidopsis thaliana (wall cress) At5g07090.1 Arabidopsis thaliana (wall cress) At5g58420.1 Arabidopsis thaliana (wall cress) 35382 Batrachochytrium dendrobatidis (chytrid fungus) 61784 Branchiostoma floridae (lancelet) 81739 Branchiostoma floridae (lancelet) XP_001892793.1 Brugia malayi (roundworm nematode) BGIBMGA010867-PA Bombyx mori (silk worm) ENSBTAP00000025024 Bos taurus (bovine) ENSBTAP00000052226 Bos taurus (bovine) CAL0004156 Candida albicans (a form of yeast) CAL0004310 Candida albicans (a form of yeast) CN11864 Caenorhabditis brenneri (small nematode) CBP01507 Caenorhabditis briggsae (nematode) CE24278 Caenorhabditis elegans (worm) ENSCAFP00000025264 Canis familiaris (dog) CAGL0F09031g Candida glabrata (haploid yeast) Chro.70527 Cryptosporidium hominis (obligate parasite) ENSCINP00000015550 Ciona intestinalis (sea squirt) JA12088 Caenorhabditis japonica (nematode) CMH218C Cyanidioschyzon merolae (red alga) cn01610 Cryptococcus neoformans (yeast-like fungus) cgd7_4760 Cryptosporidium parvum (protozoan parasite) CPIJ003013 Culex pipens (mosquito) ENSCPOP00000019511 Cavia porcellus (guinea pig) 188837 Chlamidomonas reinhardtii (green alga) RP32861 Caenorhabditis remanei (nematode) ENSCSAVP00000008862 Ciona savignyi (sedentary tunicate) 152725 Capitella spl (polychaete worm) DDB0185063 Dictyostelium discoideum (amoeba) DEHA2F03300g Debaryomyces Hansenii (yeast) DEHA2G07392g Debaryomyces Hansenii (yeast) 300650 Daphnia pulex (daphnia) ENSDARP00000014931 Danio rerio (zebra fish) ENSECAP00000008853 Equus caballus (horse) XP_648911 Entamoeba histolytica (anaerobic protozoan) XP_649211 Entamoeba histolytica (anaerobic protozoan) XP_656039 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000024775 Gymnopilus aculeatus (mushroom) ENSGALP00000039655 Gallus gallus (chicken) GL50803_11359 Giardia lamblia (flagellated protozoan) 185809 Hypsipyla robusta (cedar shoot borer) ENSP00000362744 Homo sapiens (human) ISCW024787-PA Ixodes scapularis (deer tick) KLLA0B03652g Kluyveromyces lactis (yeast) 210271 Lottia gigantea (owl limpet) LmjF13.1220 Leishmania major (virus) LmjF13.1230 Leishmania major (virus) 33368 Monocosta brevicollis (choanoflagellate) ENSMODP00000033654 Monodelphis domestica (gray opossum) ENSMMUP00000004386 Macaca mulatta (rhesus monkey) ENSMUSP00000033683 Mus musculus (house mouse) 173646 Nematostella vectensis (starlet anemone) XP_001599933.1 Nasonia vitripennis (wasp) ENSOANP00000004684 Ornithorynchus anatinus (platypus) ENSORLP00000012015 Oryzias latipes (japanese killifish) LOC_Os01g25610.1 Oryza sativa (asian rice) LOC_Os02g01560.1 Oryza sativa (asian rice) 29689 Ostreococcus tauri (green alga) PF11_0065 Plasmodium falciparum (protozoal parasite) PHUM000340-PA Pediculus humanus (human body louse) 197071 Physcomitrella patens (moss) ENSPPYP00000022909 Pongo pygmaeus (orangutan) 132408 Phytophthora sojae (root rot pathogen) 240413 Populus trichocarpa (black cottonwood) 257929 Populus trichocarpa (black cottonwood) 575195 Populus trichocarpa (black cottonwood) ENSPTRP00000037867 Pan troglodytes (chimpanzee) PVX_090950 Plasmodium vivax (protozoal parasite) ENSRNOP00000004278 Rattus norvegicus (norway rat) ENSRNOP00000043988 Rattus norvegicus (norway rat) 4751998 Sorghum bicolor (sorghum) YHR203C Saccharomyces cerevisiae (budding yeast) YJR145C Saccharomyces cerevisiae (budding yeast) Smp_011570.1 Schistosoma mansoni (trematode parasite) SPAC959.07 Schizosaccharomyces pombe (fission yeast) SPBC19F8.08 Schizosaccharomyces pombe (fission yeast) SPBC21B10.10 Schizosaccharomyces pombe (fission yeast) XP_001187213.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001192878.1 Strongylocentrotus purpuratus (purple sea urchin) 37748 Trichoplax adhaerens (metazoa) TA10515 Theileria annulata (apicomplexan parasite) XP_969262.1 Tribolium castaneum (red flour beetle) Tc00.1047053509683.117 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511051.39 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511051.50 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005439 Tetraodon nigroviridis (green spotted pufferfish) TP04_0680 Theileria parva (parasitic protozoan) 27292 Thalassiosira pseudonana (marine diatom) ENSTRUP00000020259 Takifugu rubripes (pufferfish Takifugu) 3700.m00085 Tetrahymena thermophila (ciliate protozoa) 134327.m00011 Trichomonas vaginalis (parasitic flagellated protozoan) 83641.m00158 Trichomonas vaginalis (parasitic flagellated protozoan) 84561.m00143 Trichomonas vaginalis (parasitic flagellated protozoan) 88273.m00398 Trichomonas vaginalis (parasitic flagellated protozoan) 91860.m00077 Trichomonas vaginalis (parasitic flagellated protozoan) 93440.m00415 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000056754 Xenopus tropicalis (frog) YALI0D12903g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39484 modMine - Data generated by the modENCODE project. • FBgn0011284 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16758 NV11016 LH13539 RS4_IXOSC FBgn0068048 FBgn0219424 FBgn0200686 FBgn0186109 FBgn0180252 JGI_V11_304892 JGI_V11_300650 FBgn0070939 FBgn0162914 FBgn0134511 FBgn0124613 FBgn0107867 FBgn0101021 CPIJ003013 BGIBMGA010867 ACYPI000100 GB19305 AGAP006871 PHUM601190 GLEAN_13431
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	anon-EST:Posey270   CG11276 (Cermelli et al., 2006, Huang et al., 2005, Goshima et al., 2007, Marygold et al., 2007, Worringer et al., 2009, Keleman et al., 2009.8.5, Cammarato et al., 2011) rpS4 (Yokokura, 1994.1.13) RPS4 (Yokokura et al., 1993, Bergen et al., 1998, Pinnola et al., 2007) RpS4 (Cermelli et al., 2006, Goshima et al., 2007, Isogai et al., 2007, Marygold et al., 2007, Worringer et al., 2009, Nie et al., 2009) Rp S4 (Alonso and Santaren, 2006) SX4 (Brogna et al., 2002)
Name Synonym	Ribosomal protein S4 (Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0025296
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 2 ) Patent  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 3 )
	Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Müller et al., 2010, EMBO J. 29(19): 3344--3357 Proteomic and functional analysis of the mitotic Drosophila centrosome. [FBrf0212030] Show all research papers ...