FB2019_05, released Oct 15, 2019

Gene: Dmel\TfIIA-L

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General Information
Symbol
Dmel\TfIIA-L
Species
D. melanogaster
Name
Transcription factor IIA L
Annotation Symbol
CG5930
Feature Type
protein_coding_gene
FlyBase ID
FBgn0011289
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Snapshot
Transcription factor IIA L (TfIIA-L) encodes a precursor protein that, after proteolysis, produces the two larger subunits of TFIIA. TFIIA is a general transcription factor that is required for initiation by RNA polymerase II and is a component of the pre-initiation complex. [Date last reviewed: 2018-09-13]
Other Summaries
Also Known As
TFIIA, dTFIIA
Key Links
Genomic Location
Cytogenetic map
97E11-97E11
Sequence location
3R:27,251,112..27,256,463 [+]
Recombination map
3-92
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the TFIIA subunit 1 family. (P52654)
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
contributes_to RNA polymerase II general transcription initiation factor activity; TBP-class protein binding; TFIID-class transcription factor complex binding
Predictions / Assertions
-
Summaries
Gene Group (FlyBase)
TRANSCRIPTION FACTOR II A -
The general transcription factor complex Transcription factor II A (TFIIA) is not required for basal transcription but it stabilizes the TBP-DNA complex. TFIIA is RNA Pol II-specific and stimulates constitutive transcription and activated transcription. (Adapted from PMID:25693126).
Protein Function (UniProtKB)
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
(UniProt, P52654)
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
3

Please see the GBrowse view of Dmel\TfIIA-L or the JBrowse view of Dmel\TfIIA-L for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Graveley et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
TfIIA-L-RA
FBtr0085155
NM_057647
1595
366
TfIIA-L-RB
FBtr0085156
NM_057648
1586
363
TfIIA-L-RC
FBtr0085154
NM_170329
1440
324
Additional Transcript Data and Comments
Reported size (kB)
1.8 (northern blot)
(Yokomori et al., 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
TfIIA-L-PA
FBpp0084525
39.3
366
4.32
NP_476995
AAF56687
TfIIA-L-PB
FBpp0084526
38.9
363
4.25
NP_476996
AAN14105
TfIIA-L-PC
FBpp0084524
34.5
324
4.34
NP_733208
AAN14106
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
366 (aa); 39 (kD predicted)
(Yokomori et al., 1993)
Comments
External Data
Subunit Structure (UniProtKB)
Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). TFIIA is a heterodimer of a unprocessed large subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p30), a beta (p20) and a gamma subunit (p14). Interacts with Tbp. Taf4 interacts with TFIIA-L when TFIIA-L is in complex with Tbp.
(UniProt, P52654)
Post Translational Modification
The precursor form (48 kDa) is cleaved to give rise to the alpha (30 kDa) and beta (20 kDa) subunits.
(UniProt, P52654)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TfIIA-L using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (7 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
contributes_to RNA polymerase II general transcription initiation factor activity
inferred from physical interaction with FLYBASE:TfIIA-S; FB:FBgn0013347
(Yokomori et al., 1994)
TBP-class protein binding
inferred from physical interaction with FLYBASE:Trf2; FB:FBgn0261793
(Andersen et al., 2017)
inferred from physical interaction with FLYBASE:Tbp; FB:FBgn0003687
(Yokomori et al., 1993)
TFIID-class transcription factor complex binding
inferred from physical interaction with FLYBASE:Taf4; FB:FBgn0010280
(Yokomori et al., 1993)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
transcription by RNA polymerase II
inferred from direct assay
(Yokomori et al., 1994)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN000294294
(assigned by GO_Central )
(Gaudet et al., 2011)
transcription initiation from RNA polymerase II promoter
inferred from sequence or structural similarity with SGD:S000005720
(Aoyagi and Wassarman, 2000)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
nucleus
inferred from direct assay
(Yokomori et al., 1994, Yokomori et al., 1993)
transcription factor TFIIA complex
inferred from direct assay
(Yokomori et al., 1994, Yokomori et al., 1993)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
transcription factor TFIIA complex
inferred from biological aspect of ancestor with PANTHER:PTN000294295
(assigned by GO_Central )
(Gaudet et al., 2011)
inferred from sequence or structural similarity with HGNC:4646
(Aoyagi and Wassarman, 2000)
inferred from sequence or structural similarity with SGD:S000005720
(Aoyagi and Wassarman, 2000)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
nucleus
inferred from direct assay
(Yokomori et al., 1994, Yokomori et al., 1993)
transcription factor TFIIA complex
inferred from direct assay
(Yokomori et al., 1994, Yokomori et al., 1993)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\TfIIA-L in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 7 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of TfIIA-L
Transgenic constructs containing regulatory region of TfIIA-L
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
fertile
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\GTF2A1
10 of 15
Yes
Yes
 
Hsap\GTF2A1L
6 of 15
Yes
No
Hsap\STON1-GTF2A1L
4 of 15
No
No
Hsap\STON2
2 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (4)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Gtf2a1
11 of 15
Yes
Yes
Mmus\Gtf2a1l
8 of 15
No
Yes
Mmus\Ston1
2 of 15
No
No
Mmus\Ston2
1 of 15
No
No
Rattus norvegicus (Norway rat) (4)
Rnor\Gtf2a1
10 of 13
Yes
Yes
Rnor\Gtf2a1l
8 of 13
No
Yes
Rnor\Ston1
1 of 13
No
No
Rnor\Ston2
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (2)
Xtro\gtf2a1
6 of 12
Yes
Yes
Xtro\gtf2a1l
3 of 12
No
Yes
Danio rerio (Zebrafish) (3)
Drer\gtf2a1
11 of 15
Yes
Yes
Drer\gtf2a1l
7 of 15
No
Yes
Drer\ston1
2 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\pqn-51
10 of 15
Yes
Yes
Cele\unc-41
2 of 15
No
No
Arabidopsis thaliana (thale-cress) (3)
Atha\AT1G07470
6 of 9
Yes
Yes
Atha\AT1G07480
6 of 9
Yes
Yes
Atha\AT5G59230
5 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\TOA1
11 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\toa1
10 of 12
Yes
Yes
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190EOZ )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\TfIIA-L
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00010129
Drosophila simulans
Dsim\GD21332
Drosophila sechellia
Dsec\GM10381
Drosophila erecta
Dere\GG11539
Drosophila yakuba
Dyak\GE23726
Drosophila ananassae
Dana\GF16279
Drosophila pseudoobscura pseudoobscura
Dpse\GA19238
Drosophila persimilis
Dper\GL24482
Drosophila willistoni
Dwil\GK22574
Drosophila virilis
Dvir\GJ24046
Drosophila mojavensis
Dmoj\GI22255
Drosophila grimshawi
Dgri\GH19494
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091509Q9 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17006426
Glossina morsitans
Tsetse fly
Gmor\GMOY005412
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12412
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL007022
Anopheles darlingi
American malaria mosquito
Adar\ADAC004996
Anopheles gambiae
Malaria mosquito
Agam\AGAP002958
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002554
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0GXK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA011737
Danaus plexippus
Monarch butterfly
Dple\DPOGS204845-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL006331
Apis florea
Little honeybee
Aflo\3943707556
Apis mellifera
Western honey bee
Amel\GB40881
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11913
Bombus terrestris
Buff-tailed bumblebee
Bter\15216847
Linepithema humile
Argentine ant
Lhum\LH13336
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0005d6
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG025152
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09079
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12951
Tribolium castaneum
Red flour beetle
Tcas\TC011708
Pediculus humanus
Human body louse
Phum\PHUM435190
Cimex lectularius
Bed bug
Clec\CLEC007352
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009376
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02829
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0MS8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR004510
Ixodes scapularis
Black-legged tick
Isca\ISCW021579
Stegodyphus mimosarum
African social velvet spider
Smim\KFM72029.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM72028.1
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_304824
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0GC2 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Ston2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-GtfIIA1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-TfIIAaLp
Ciona intestinalis
Vase tunicate
Cint\LOC100183638
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000001829
Gallus gallus
Domestic chicken
Ggal\GTF2A1
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000026747
Gallus gallus
Domestic chicken
Ggal\STON2
Gallus gallus
Domestic chicken
Ggal\421307
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (1)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
stnB
2 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    GTF2A1; general transcription factor IIA subunit 1
    10 of 15
    600520
         
        GTF2A1L; general transcription factor IIA subunit 1 like
        6 of 15
        605358
            STON1-GTF2A1L; STON1-GTF2A1L readthrough
            4 of 15
                Functional Complementation Data
                Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                Interactions
                Summary of Physical Interactions
                Summary of Genetic Interactions
                esyN Network Diagram
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                External Data
                Subunit Structure (UniProtKB)
                Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). TFIIA is a heterodimer of a unprocessed large subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p30), a beta (p20) and a gamma subunit (p14). Interacts with Tbp. Taf4 interacts with TFIIA-L when TFIIA-L is in complex with Tbp.
                (UniProt, P52654 )
                Linkouts
                BioGRID - A database of protein and genetic interactions.
                DroID - A comprehensive database of gene and protein interactions.
                InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                MIST (protein-protein) - An integrated Molecular Interaction Database
                Pathways
                Genomic Location and Detailed Mapping Data
                Chromosome (arm)
                3R
                Recombination map
                3-92
                Cytogenetic map
                97E11-97E11
                Sequence location
                3R:27,251,112..27,256,463 [+]
                FlyBase Computed Cytological Location
                Cytogenetic map
                Evidence for location
                97E11-97E11
                Limits computationally determined from genome sequence between P{PZ}sda03884 and P{PZ}btzrL203
                Experimentally Determined Cytological Location
                Cytogenetic map
                Notes
                References
                97F-97F
                (determined by in situ hybridisation)
                (Wismar et al., 1997)
                Experimentally Determined Recombination Data
                Location
                3-92
                (FlyBase, 2016)
                3-90.0
                (Comeron et al., 2012)
                3-
                (Wismar et al., 1997)
                Left of (cM)
                Right of (cM)
                Notes
                Stocks and Reagents
                Stocks (11)
                Genomic Clones (11)
                 

                Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                cDNA Clones (58)
                 

                Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                cDNA clones, fully sequences
                BDGP DGC clones
                Other clones
                  Drosophila Genomics Resource Center cDNA clones

                  For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                  cDNA Clones, End Sequenced (ESTs)
                  BDGP DGC clones
                  Other clones
                  RNAi and Array Information
                  Linkouts
                  DRSC - Results frm RNAi screens
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  Antibody Information
                  Laboratory Generated Antibodies
                   
                  polyclonal
                  (Yokomori et al., 1993)
                  Commercially Available Antibodies
                   
                  Other Information
                  Relationship to Other Genes
                  Source for database identify of
                  Source for database merge of
                  Additional comments
                  Other Comments
                  Recombinant purified TfIIA-L and TfIIA-S can form a stable complex with Tbp on DNA, the recombinant protein can stimulate basal transcription and enhances transcriptional activation.
                  (Yokomori et al., 1994)
                  The TfIIA-L gene product is a 30kD polypeptide associated with Tbp, the polypeptide has been purified, molecularly cloned, expressed and partially characterised.
                  (Yokomori et al., 1993)
                  Origin and Etymology
                  Discoverer
                  Etymology
                  Identification
                  External Crossreferences and Linkouts ( 56 )
                  Sequence Crossreferences
                  NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                  GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                  GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                  RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                  UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                  Other crossreferences
                  BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                  Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                  Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                  Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                  Flygut - An atlas of the Drosophila adult midgut
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                  InterPro - A database of protein families, domains and functional sites
                  KEGG Genes - Molecular building blocks of life in the genomic space.
                  KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                  modMine - A data warehouse for the modENCODE project
                  Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                  Linkouts
                  BioGRID - A database of protein and genetic interactions.
                  DroID - A comprehensive database of gene and protein interactions.
                  DRSC - Results frm RNAi screens
                  FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                  FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                  FlyMine - An integrated database for Drosophila genomics
                  InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                  KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                  MIST (protein-protein) - An integrated Molecular Interaction Database
                  Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                  Synonyms and Secondary IDs (9)
                  Datasets (0)
                  Study focus (0)
                  Experimental Role
                  Project
                  Project Type
                  Title
                  References (67)