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Gene Dmel\Taf12

General Information
Symbol	Dmel\Taf12	Species	D. melanogaster
Name	TBP-associated factor 12	Annotation symbol	CG17358
Feature type	protein_coding_gene	FlyBase ID	FBgn0011290
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	Taf30α, dTAFII30α, TFIID, TAFII30α, dTAF12, dTAFII30, p28, p22
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	86E15-86E15	Sequence location	3R:7,504,099..7,505,408 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene TBP-associated factor 12 is referred to in FlyBase by the symbol Dmel\Taf12 (CG17358, FBgn0011290). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; transcription factor binding; protein homodimerization activity; sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Histone-fold; Transcription initiation factor TFIID. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult brain. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625702_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of Taf12. Gene sequence location is 3R:7504099..7505408.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
FB2012_01	Sequence features HFA16879 BKN28054 BKN45351 Controlled Vocabulary Terms SAGA complex TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly protein homodimerization activity transcription factor binding sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 86E15-86E15   Limits computationally determined from genome sequence between P{PZ}tho1&P{PZ}l(3)0462905275 and P{EP}Lk6EP886
Experimentally Determined Cytological Location
Cytogenetic map Notes References 86F1-86F2     (Yokomori, 1994.2.25)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Taf12 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Taf12-RA FBtr0082442  NM_079596   1191   196 Taf12-RB FBtr0082440  NM_169420   1071   196 Taf12-RD FBtr0290205  NM_169421   857   160
Additional Transcript Data & Comments
Reported size (kB)	1.4 (northern blot) (Yokomori et al., 1993) 0.8 (longest cDNA) (Kokubo et al., 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Taf12-PA   FBpp0081918   21.5   196   7.15     NP_524320   AAF54677 Taf12-PB   FBpp0081916   21.5   196   7.15     NP_731616   AAF54678 Taf12-PD   FBpp0288644   17.6   160   9.47     NP_731617   AAF54679
Additional Polypeptide Data & Comments
Reported size (kDa)	196 (aa); 22 (kD predicted) (Yokomori et al., 1993) 196, 160 (aa); 28, 22 (kD observed); 22, 18 (kD predicted) (Kokubo et al., 1994) 32 (kD) (Dynlacht et al., 1991)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Transcription initiation factor TFIID (IPR003228) Histone-fold (IPR009072)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAF54677   AE014297 AAF54678   AE014297 AAF54679   AI389237   AI456327   AI512256   AI515806   AI518106   AI542036   AW943333   AY061435 AAL28983   BG633115   BI171463   BI565176   BI567804   BI573686   BI573687   BI588931   BI604958   BP556225   BP556226   BP556678   BP556679   BP556735   CO179083   CO179572   CO186353   CO268959   CO272228   CO282203   CO283556   CO290959   CO325318   CO327904   CO343426   EC058377   EC080187   EC202587   EC209210   EC210900   EC218807   EC219280   EC223944   EC246823   EC247884   EC254070   EC260588   EV577197   S67741 AAB29540   U06450 AAC46479   U06456 AAB19244
UniProtKB/Swiss-Prot	P49905
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0011290    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0011290 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0011290 expression level Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5963) embryo 02-04hr  (8026) embryo 04-06hr  (5894) embryo 06-08hr  (5190) embryo 08-10hr  (5206) embryo 10-12hr  (5153) embryo 12-14hr  (3382) embryo 14-16hr  (3781) embryo 16-18hr  (2610) embryo 18-20hr  (1859) embryo 20-22hr  (2275) embryo 22-24hr  (2239) larva L1  (1661) larva L2  (1309) larva L3 12hr old  (1046) larva L3 puffstage 1-2  (1098) larva L3 puffstage 3-6  (1625) larva L3 puffstage 7-9  (2215) white prepupae new  (2114) white prepupae 12hr  (2140) white prepupae 24hr  (2481) pupae 2d postWPP  (2398) pupae 3d postWPP  (1413) pupae 4d postWPP  (1317) adult male 01day  (1182) adult male 05day  (1323) adult male 30day  (1574) adult female 01day  (2577) adult female 05day  (3162) adult female 30day  (3346) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5963) embryo 02-04hr  (8026) embryo 04-06hr  (5894) embryo 06-08hr  (5190) embryo 08-10hr  (5206) embryo 10-12hr  (5153) embryo 12-14hr  (3382) embryo 14-16hr  (3781) embryo 16-18hr  (2610) embryo 18-20hr  (1859) embryo 20-22hr  (2275) embryo 22-24hr  (2239) larva L1  (1661) larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6  (1625) larva L3 puffstage 7-9  (2215) white prepupae new  (2114) white prepupae 12hr  (2140) white prepupae 24hr  (2481) pupae 2d postWPP  (2398) pupae 3d postWPP  1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day  (1574) adult female 01day  (2577) adult female 05day  (3162) adult female 30day  (3346) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0011290 expression level Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5963) embryo 02-04hr  (8026) embryo 04-06hr  (5894) embryo 06-08hr  (5190) embryo 08-10hr  (5206) embryo 10-12hr  (5153) embryo 12-14hr  (3382) embryo 14-16hr  (3781) embryo 16-18hr  (2610) embryo 18-20hr  (1859) embryo 20-22hr  (2275) embryo 22-24hr  (2239) larva L1  (1661) larva L2  (1309) larva L3 12hr old  (1046) larva L3 puffstage 1-2  (1098) larva L3 puffstage 3-6  (1625) larva L3 puffstage 7-9  (2215) white prepupae new  (2114) white prepupae 12hr  (2140) white prepupae 24hr  (2481) pupae 2d postWPP  (2398) pupae 3d postWPP  (1413) pupae 4d postWPP  (1317) adult male 01day  (1182) adult male 05day  (1323) adult male 30day  (1574) adult female 01day  (2577) adult female 05day  (3162) adult female 30day  (3346) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5963) embryo 02-04hr  (8026) embryo 04-06hr  (5894) embryo 06-08hr  (5190) embryo 08-10hr  (5206) embryo 10-12hr  (5153) embryo 12-14hr  (3382) embryo 14-16hr  (3781) embryo 16-18hr  (2610) embryo 18-20hr  1859 embryo 20-22hr  2275 embryo 22-24hr  2239 larva L1  1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6  1625 larva L3 puffstage 7-9  2215 white prepupae new  2114 white prepupae 12hr  2140 white prepupae 24hr  (2481) pupae 2d postWPP  2398 pupae 3d postWPP  1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day  1574 adult female 01day  (2577) adult female 05day  (3162) adult female 30day  (3346) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5963 embryo 02-04hr    8026 embryo 04-06hr    5894 embryo 06-08hr    5190 embryo 08-10hr    5206 embryo 10-12hr    5153 embryo 12-14hr    3382 embryo 14-16hr    3781 embryo 16-18hr    2610 embryo 18-20hr    1859 embryo 20-22hr    2275 embryo 22-24hr    2239 larva L1    1661 larva L2    1309 larva L3 12hr old    1046 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1625 larva L3 puffstage 7-9    2215 white prepupae new    2114 white prepupae 12hr    2140 white prepupae 24hr    2481 pupae 2d postWPP    2398 pupae 3d postWPP    1413 pupae 4d postWPP    1317 adult male 01day    1182 adult male 05day    1323 adult male 30day    1574 adult female 01day    2577 adult female 05day    3162 adult female 30day    3346 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0011290    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0011290 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult brain. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0011290 expression level Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain  (550.9) Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0011290 expression level Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain  550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    375.525 Larval Midgut    75.1 Larval Hindgut    91.5 Larval Malpighian Tubules    143.3 Larval Fat Body    100.9 Larval Salivary Gland    175.5 Larval Trachea    211.25 Larval Carcass    145.85 Adult Head    206.3 Adult Eye    333.175 Adult Brain    550.9 Adult Thoracic-Abdominal Ganglion    382.6 Adult Crop    189.3 Adult Midgut    93.2 Adult Hindgut    149.6 Adult Malpighian Tubules    108.9 Adult Fat Body    77.7 Adult Salivary Gland    197.2 Adult Heart    133.55 Adult VirginFemale Spermatheca    62.4 Adult InseminatedFemale Spermatheca    69.1 Adult Ovary    340.2 Adult Testis    46.5 Adult Male Accessory Gland    270.6 Adult Carcass    121.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    206.3   NA  Eye    333.175   NA  Brain    550.9   375.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    382.6   NA  Crop    189.3   75.1  Midgut    93.2   91.5  Hindgut    149.6   143.3  Malpighian Tubules    108.9   100.9  Fat Body    77.7   175.5  Salivary Gland    197.2   NA  Heart    133.55   211.25  Trachea    NA   NA  VirginFemale Spermatheca    62.4   NA  InseminatedFemale Spermatheca    69.1   NA  Ovary    340.2   NA  Testis    46.5   NA  Male Accessory Gland    270.6   145.85  Carcass    121.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011290 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17358-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 Taf12GD4149 lethal | pupal stage, with Scer\GAL4pnr-MD237 Taf12GD4149 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 Taf12GD4149 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage, with Scer\GAL41407 Taf12GD4149 ganglion mother cell | larval stage, with Scer\GAL41407 Taf12GD4149
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Taf12 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Taf12 Class Mutagen Stocks Known lesion Taf12GD4149 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf12HMS00170 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf12dsRNA.cWa in vitro construct - RNAi 0 Yes Taf12KK108054 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel7309 (Ryder, 2004.4.26) Df(3R)Exel8154 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4149} NA P{KK108054} NA P{TRiP.HMS00170} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )
Terms Based on Experimental Evidence ( 8 terms )
Molecular Function
CV term Evidence References
protein homodimerization activity inferred from physical interaction with Taf12 (Yokomori et al., 1993) contributes_to sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly inferred from direct assay (Yokomori et al., 1993) TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly inferred from physical interaction with Tbp (Yokomori et al., 1993) transcription factor binding inferred from physical interaction with Taf1 (Yokomori et al., 1993) inferred from physical interaction with Taf4 (Yokomori et al., 1993)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Weake et al., 2011, Yokomori et al., 1993) SAGA complex inferred from direct assay (Weake et al., 2011) transcription factor TFIID complex inferred from direct assay (Yokomori et al., 1993)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR009072 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription initiation from RNA polymerase II promoter inferred from sequence or structural similarity with human TAF12 AND inferred from sequence or structural similarity with Saccharomyces TAF61 (Aoyagi and Wassarman, 2000)
Cellular Component
CV term Evidence References
nucleus non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription factor TFIID complex inferred from sequence or structural similarity with human TAF12 AND inferred from sequence or structural similarity with Saccharomyces TAF61 (Aoyagi and Wassarman, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Taf12 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66532 DroID - A comprehensive database of gene and protein interactions. • FBgn0011290 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41406
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16626 Dere\GG17205 Dgri\GH19321 Dmoj\GI23544 Dper\GL12259 Dpse\GA14477 Dsec\GM26083 Dsim\GD20646 Dvir\GJ10291 Dwil\GK11997 Dyak\GE10098
Curated drosophilid orthologs	Dpse\GA14477
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008363-PC Aedes aegypti (mosquito) AGAP003135-PA Anopheles gambiae (mosquito) XP_393786.2 Apis mellifera (honey bee) 91938 Batrachochytrium dendrobatidis (chytrid fungus) 231565 Branchiostoma floridae (lancelet) XP_001895701.1 Brugia malayi (roundworm nematode) ENSBTAP00000037817 Bos taurus (bovine) CN10674 Caenorhabditis brenneri (small nematode) CE31842 Caenorhabditis elegans (worm) ENSCAFP00000017254 Canis familiaris (dog) CAGL0E01397g Candida glabrata (haploid yeast) CMS144C Cyanidioschyzon merolae (red alga) CPIJ011778 Culex pipens (mosquito) ENSCPOP00000008125 Cavia porcellus (guinea pig) 172500 Chlamidomonas reinhardtii (green alga) RP35866 Caenorhabditis remanei (nematode) 162600 Capitella spl (polychaete worm) 302673 Daphnia pulex (daphnia) ENSDARP00000070570 Danio rerio (zebra fish) ENSDARP00000070699 Danio rerio (zebra fish) ENSECAP00000010399 Equus caballus (horse) XP_656036 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000018494 Gymnopilus aculeatus (mushroom) ENSGALP00000001461 Gallus gallus (chicken) 159763 Hypsipyla robusta (cedar shoot borer) ENSP00000263974 Homo sapiens (human) 58640 Lottia gigantea (owl limpet) ENSMODP00000013695 Monodelphis domestica (gray opossum) ENSMMUP00000007585 Macaca mulatta (rhesus monkey) ENSMUSP00000101583 Mus musculus (house mouse) 139976 Nematostella vectensis (starlet anemone) XP_001605166.1 Nasonia vitripennis (wasp) ENSOANP00000007130 Ornithorynchus anatinus (platypus) LOC_Os01g63940.1 Oryza sativa (asian rice) 9439 Ostreococcus tauri (green alga) PHUM003837-PA Pediculus humanus (human body louse) 27365 Physcomitrella patens (moss) ENSPPYP00000001889 Pongo pygmaeus (orangutan) 72921 Phytophthora ramorum (sudden oak death pathogen) 143377 Phytophthora sojae (root rot pathogen) ENSPTRP00000000760 Pan troglodytes (chimpanzee) ENSRNOP00000054419 Rattus norvegicus (norway rat) 5054054 Sorghum bicolor (sorghum) XP_001185712.1 Strongylocentrotus purpuratus (purple sea urchin) 31979 Trichoplax adhaerens (metazoa) XP_966374.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008394 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000003794 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000044540 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13964 LH20429 FBgn0227980 FBgn0214008 FBgn0197577 FBgn0192112 FBgn0180938 JGI_V11_302673 FBgn0074505 FBgn0149866 FBgn0146270 FBgn0126786 FBgn0109432 FBgn0093647 CPIJ011778 BGIBMGA010172 ACYPI26209 GB18576 AGAP003135 AAEL008363 PB22784 PHUM507150 GLEAN_07989
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	34852 y1 sc* v1; P{TRiP.HMS00170}attP2
VDRC	v12654 w1118; P{GD4149}v12654
Genomic Clones ( 1 )
	BACR11G22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 39 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD36256
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD37527 LD41478 LD44034 RE13247 RH30392 RH38390 RH62872 RH70465 SD08078
Other clones	8011 44327 67229 69831 97138 105875 214279.52 214481.51 CK01.15B.E6 CK01.74B.C12 CK01.76C.E4 CK01.97C.D10 Dmel_dig_012972_0589_3008 EK019006 EK058344 EK059838 EK075645 EK093201 EK106325 EK159764 EK163644 EK196115 EP08235 EP16749 FGM302B02 FGM304H08 FGM305C03 GH20363 RH09234
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011290 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41406
Antibody Information
	polyclonal (Yokomori et al., 1993)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Marr et al., 2006) The proteins encoded by Taf4, Taf5, Taf6, e(y)1 and Taf12 form a core sub-complex of TFIID. (Wright et al., 2006) Does not interact, in vitro, with human thryroid-hormone receptor-β. (Petty et al., 1996) The assembly and purification of various functional Tbp TAF complexes demonstrate that Tbp plus the TAFs is sufficient to replace endogenous TFIID to support activated transcription in vitro. (Chen et al., 1994) The 28kD and 22kD proteins are products of the same gene, with the smaller being an N-truncated version of the larger. TFIID subunit proteins and the Tbp protein can interact in pairwise combinations with several subunits in a network of interactions within TFIID. (Kokubo et al., 1994) A number of polypeptides (encoded by Taf1, Taf4, Taf5, Taf6, e(y)1 and Taf12) that are tightly associated with Tbp and are native TFIID components have been purified. Protein blotting experiments suggest that one of these proteins, Taf1, interacts directly with Tbp, while the association between Tbp and the other proteins is either weak or is an indirect association via Taf1. (Kokubo et al., 1993) Taf12 and Taf11 join the TfIID complex through interaction with one or more of the larger subunits and only Taf12 may be in contact with Tbp. (Yokomori et al., 1993) A TATA-dependent protein-DNA complex is found in fractionated embryonic nuclear extracts. DNase I footprint analysis identifies polypeptides (including Taf12, Tbp and RpII140) that require the Hsp70Bb TATA element for binding to regions of the Hsp70Bb promoter. (Gilmour et al., 1990)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079596 NM_169420 NM_169421 RefSeq (Proteins) • NP_524320 NP_731616 NP_731617 DDBJ / EMBL / GenBank • AAB19244 AAB29540 AAC46479 AAF54677 AAF54678 AAF54679 AAL28983 AI456327 AW943333 AY061435 S67741 U06450 U06456 Entrez Gene - A searchable database of RefSeq genes. • 41406 UniProtKB/Swiss-Prot • P49905
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Transcription initiation factor TFIID (IPR003228) Histone-fold (IPR009072)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66532 DroID - A comprehensive database of gene and protein interactions. • FBgn0011290 DRSC - Results from RNAi screens. • FBgn0011290 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011290 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17358-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011290 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41406 InParanoid A subset of ortholog calls from InParanoid. • AAEL008363-PC Aedes aegypti (mosquito) AGAP003135-PA Anopheles gambiae (mosquito) XP_393786.2 Apis mellifera (honey bee) 91938 Batrachochytrium dendrobatidis (chytrid fungus) 231565 Branchiostoma floridae (lancelet) XP_001895701.1 Brugia malayi (roundworm nematode) ENSBTAP00000037817 Bos taurus (bovine) CN10674 Caenorhabditis brenneri (small nematode) CE31842 Caenorhabditis elegans (worm) ENSCAFP00000017254 Canis familiaris (dog) CAGL0E01397g Candida glabrata (haploid yeast) CMS144C Cyanidioschyzon merolae (red alga) CPIJ011778 Culex pipens (mosquito) ENSCPOP00000008125 Cavia porcellus (guinea pig) 172500 Chlamidomonas reinhardtii (green alga) RP35866 Caenorhabditis remanei (nematode) 162600 Capitella spl (polychaete worm) 302673 Daphnia pulex (daphnia) ENSDARP00000070570 Danio rerio (zebra fish) ENSDARP00000070699 Danio rerio (zebra fish) ENSECAP00000010399 Equus caballus (horse) XP_656036 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000018494 Gymnopilus aculeatus (mushroom) ENSGALP00000001461 Gallus gallus (chicken) 159763 Hypsipyla robusta (cedar shoot borer) ENSP00000263974 Homo sapiens (human) 58640 Lottia gigantea (owl limpet) ENSMODP00000013695 Monodelphis domestica (gray opossum) ENSMMUP00000007585 Macaca mulatta (rhesus monkey) ENSMUSP00000101583 Mus musculus (house mouse) 139976 Nematostella vectensis (starlet anemone) XP_001605166.1 Nasonia vitripennis (wasp) ENSOANP00000007130 Ornithorynchus anatinus (platypus) LOC_Os01g63940.1 Oryza sativa (asian rice) 9439 Ostreococcus tauri (green alga) PHUM003837-PA Pediculus humanus (human body louse) 27365 Physcomitrella patens (moss) ENSPPYP00000001889 Pongo pygmaeus (orangutan) 72921 Phytophthora ramorum (sudden oak death pathogen) 143377 Phytophthora sojae (root rot pathogen) ENSPTRP00000000760 Pan troglodytes (chimpanzee) ENSRNOP00000054419 Rattus norvegicus (norway rat) 5054054 Sorghum bicolor (sorghum) XP_001185712.1 Strongylocentrotus purpuratus (purple sea urchin) 31979 Trichoplax adhaerens (metazoa) XP_966374.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008394 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000003794 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000044540 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41406 modMine - Data generated by the modENCODE project. • FBgn0011290 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13964 LH20429 FBgn0227980 FBgn0214008 FBgn0197577 FBgn0192112 FBgn0180938 JGI_V11_302673 FBgn0074505 FBgn0149866 FBgn0146270 FBgn0126786 FBgn0109432 FBgn0093647 CPIJ011778 BGIBMGA010172 ACYPI26209 GB18576 AGAP003135 AAEL008363 PB22784 PHUM507150 GLEAN_07989
Synonyms & Secondary IDs ( 41 )
Reported As
Symbol Synonym	CG17358 (Laszlo, 2002, Aoyagi and Wassarman, 2000, Keleman et al., 2009.8.5, Ni et al., 2011.7.19) d28/22 (Pugh, 2000) dmTAF12 (Laszlo, 2002) dTAF12 (Hiller et al., 2004, Guelman et al., 2006) dTAF22 (Hoffmann et al., 1996) dTAF28 (Hoffmann et al., 1996) dTAFII30 (Mantovani, 1999, Burke and Kadonaga, 1997) dTAFII30α (Gangloff et al., 2001, Veenstra and Wolffe, 2001, Lively et al., 2001, Albright and Tjian, 2000, Zhou et al., 1998, Goodrich and Tjian, 1994, Wright et al., 2006) dTAFII30α/22 (Burley, 1998) dTAFII30 (Deak et al., 1997) dTAFII30 alpha (Yokomori, 1994.2.25) p22 (Kokubo et al., 1994, Kokubo et al., 1993) p28 (Kokubo et al., 1994, Kokubo et al., 1993) T2DA_DROME (Storm and Sonnhammer, 2003) TAF (Mueller and Tora, 2004) TAF12 (Tora, 2002, Marr et al., 2006, Wright et al., 2006, Weake et al., 2011, Wright and Tjian, 2009, Weake et al., 2009, Santoso and Kadonaga, 2006) Taf12 (Zhou et al., 2008, Neumüller et al., 2011) Taf22   Taf28   TAF30a (Hansen et al., 1997) Taf30α (Bell and Tora, 1999, Struhl and Moqtaderi, 1998, Verrijzer et al., 1995, Hori and Carey, 1994, Yokomori et al., 1993, Hoey et al., 1993, Dynlacht et al., 1991, ) TAF30α (Hahn, 1998, Deak et al., 1997) TAF30α/28 (Aoyagi and Wassarman, 2000) TAF30α/28/22 (Green, 2000) Taf32   TAFII (Arnosti, 2002) TAFII30α (Wassarman and Sauer, 2001, Sauer et al., 1996, Hansen and Tjian, 1995) TafII30α (Chen et al., 1994) TAFII30α/28/22 (Tansey and Herr, 1997) TAFII30α/28 TAFII22 (Shen et al., 1998) TAFII230 (Tora, 2002) TAFII30α (Kennett et al., 2002) TAFII30α/22 (Berk, 1999) TFIID (Butler and Kadonaga, 2002, Hochheimer et al., 2002, Gu et al., 2002, Stathopoulos and Levine, 2002, Mizuguchi et al., 2001) TFIID 22 (Nakatani, 1994.2.8) TFIID 28 (Nakatani, 1994.2.8) TFIID-p28
Name Synonym	26kDa polypeptide (Gilmour et al., 1990) TBP-associated factor (Schuettengruber, 2006) TBP-associated factor 12   TBP-associated factor 30kD subunit α (Bell and Tora, 1999, Struhl and Moqtaderi, 1998, Verrijzer et al., 1995, Hori and Carey, 1994, Yokomori et al., 1993, Hoey et al., 1993, Dynlacht et al., 1991, )
Secondary FlyBase IDs
	FBgn0011303 FBgn0011304
References ( 77 )
Generate a list of	All references relating to this gene ( 77 )
List References by type	Research paper  ( 33 ) Supplementary material  ( 4 ) Review  ( 22 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 3 ) Letter  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 2 )
	Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Weake et al., 2011, Genes Dev. 25(14): 1499--1509 Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. [FBrf0214372] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...