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Gene Dmel\Taf11

General Information
Symbol	Dmel\Taf11	Species	D. melanogaster
Name	TBP-associated factor 11	Annotation symbol	CG4079
Feature type	protein_coding_gene	FlyBase ID	FBgn0011291
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	dTAFII30β, TAF30β, TAFII30β, TAF11, TFIID, dTAFII30
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	30C7-30C7	Sequence location	2L:9,762,364..9,763,244 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene TBP-associated factor 11 is referred to in FlyBase by the symbol Dmel\Taf11 (CG4079, FBgn0011291). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: transcription factor binding; sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly. Based on sequence similarity, it is predicted to be involved in the biological process: transcription initiation from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Histone-fold; TAFII28-like protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1636486_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Taf11. Gene sequence location is 2L:9762364..9763244.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Clones FI15907 Sequence features HFA03448 BKN27818 Controlled Vocabulary Terms transcription factor binding sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 30C7-30C7   Limits computationally determined from genome sequence between P{lacW}zf30Ck02506&P{EP}undEP424 and P{lacW}l(2)k06416k06416&P{lacW}sopk04603
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Taf11 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Taf11-RA FBtr0079924  NM_164871   819   196
Additional Transcript Data & Comments
Reported size (kB)	0.75 (longest cDNA) (Yokomori et al., 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Taf11-PA   FBpp0079514   22.1   196   4.59     NP_723484   AAF52806
Additional Polypeptide Data & Comments
Reported size (kDa)	196 (aa); 22 (kD predicted) (Yokomori et al., 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • TAFII28-like protein (IPR006809) Histone-fold (IPR009072)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52806   AI259909   BT132724   CO285491   CO342028   CZ469262   EC229052   EC252929   S67660 AAB29541   U06457 AAB19245
UniProtKB/Swiss-Prot	P49906
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0011291    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0011291 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0011291 expression level Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (3042) embryo 04-06hr  (2224) embryo 06-08hr  (3124) embryo 08-10hr  (3213) embryo 10-12hr  (3121) embryo 12-14hr  (1841) embryo 14-16hr  (1374) embryo 16-18hr  (939) embryo 18-20hr  (737) embryo 20-22hr  (1064) embryo 22-24hr  (1017) larva L1  (723) larva L2  (751) larva L3 12hr old  (710) larva L3 puffstage 1-2  (681) larva L3 puffstage 3-6  (1152) larva L3 puffstage 7-9  (1317) white prepupae new  (1404) white prepupae 12hr  (1492) white prepupae 24hr  (1812) pupae 2d postWPP  (1176) pupae 3d postWPP  (557) pupae 4d postWPP  (532) adult male 01day  (471) adult male 05day  (572) adult male 30day  (541) adult female 01day  (998) adult female 05day  (1616) adult female 30day  (1563) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (3042) embryo 04-06hr  (2224) embryo 06-08hr  (3124) embryo 08-10hr  (3213) embryo 10-12hr  (3121) embryo 12-14hr  (1841) embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new  1404 white prepupae 12hr  1492 white prepupae 24hr  (1812) pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day  (1616) adult female 30day  (1563) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0011291 expression level Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (3042) embryo 04-06hr  (2224) embryo 06-08hr  (3124) embryo 08-10hr  (3213) embryo 10-12hr  (3121) embryo 12-14hr  (1841) embryo 14-16hr  (1374) embryo 16-18hr  (939) embryo 18-20hr  (737) embryo 20-22hr  (1064) embryo 22-24hr  (1017) larva L1  (723) larva L2  (751) larva L3 12hr old  (710) larva L3 puffstage 1-2  (681) larva L3 puffstage 3-6  (1152) larva L3 puffstage 7-9  (1317) white prepupae new  (1404) white prepupae 12hr  (1492) white prepupae 24hr  (1812) pupae 2d postWPP  (1176) pupae 3d postWPP  (557) pupae 4d postWPP  (532) adult male 01day  (471) adult male 05day  (572) adult male 30day  (541) adult female 01day  (998) adult female 05day  (1616) adult female 30day  (1563) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2670) embryo 02-04hr  (3042) embryo 04-06hr  2224 embryo 06-08hr  (3124) embryo 08-10hr  (3213) embryo 10-12hr  (3121) embryo 12-14hr  1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new  1404 white prepupae 12hr  1492 white prepupae 24hr  1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day  1616 adult female 30day  1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2670 embryo 02-04hr    3042 embryo 04-06hr    2224 embryo 06-08hr    3124 embryo 08-10hr    3213 embryo 10-12hr    3121 embryo 12-14hr    1841 embryo 14-16hr    1374 embryo 16-18hr    939 embryo 18-20hr    737 embryo 20-22hr    1064 embryo 22-24hr    1017 larva L1    723 larva L2    751 larva L3 12hr old    710 larva L3 puffstage 1-2    681 larva L3 puffstage 3-6    1152 larva L3 puffstage 7-9    1317 white prepupae new    1404 white prepupae 12hr    1492 white prepupae 24hr    1812 pupae 2d postWPP    1176 pupae 3d postWPP    557 pupae 4d postWPP    532 adult male 01day    471 adult male 05day    572 adult male 30day    541 adult female 01day    998 adult female 05day    1616 adult female 30day    1563 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0011291    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0011291 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0011291 expression level Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0011291 expression level Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    70.3   NA  Eye    102.6   NA  Brain    118   188.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    107.7   NA  Crop    94   68.4  Midgut    79.2   83.9  Hindgut    81.3   109.7  Malpighian Tubules    60.1   85  Fat Body    68.9   186.7  Salivary Gland    127.9   NA  Heart    82.575   148.575  Trachea    NA   NA  VirginFemale Spermatheca    74.2   NA  InseminatedFemale Spermatheca    87.7   NA  Ovary    209.9   NA  Testis    66.5   NA  Male Accessory Gland    157.3   99.525  Carcass    64.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_30
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011291 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4079-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 Taf11GD4059 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Taf11 Class Mutagen Stocks Known lesion Taf11MB11995 1 -- Taf11c04450 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Taf11 Class Mutagen Stocks Known lesion Taf11GD4059 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf11KK107818 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf11dsRNA.cWa in vitro construct - RNAi 0 Yes Taf11t4.3 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4059} NA P{KK107818} NA characterization construct P{und+t4.3} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}Taf11c04450 NA insertion of enhancer trap binary system Mi{ET1}Taf11MB11995 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
contributes_to sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly inferred from direct assay (Yokomori et al., 1993) transcription factor binding inferred from physical interaction with Taf1 (Yokomori et al., 1993) inferred from physical interaction with Taf2 (Yokomori et al., 1993)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Yokomori et al., 1993) transcription factor TFIID complex inferred from direct assay (Yokomori et al., 1993)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR009072 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription initiation from RNA polymerase II promoter inferred from sequence or structural similarity with human TAF11 AND inferred from sequence or structural similarity with Saccharomyces TAF40 (Aoyagi and Wassarman, 2000)
Cellular Component
CV term Evidence References
nucleus non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription factor TFIID complex inferred from sequence or structural similarity with human TAF11 AND inferred from sequence or structural similarity with Saccharomyces TAF40 (Aoyagi and Wassarman, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Taf11 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60390 DroID - A comprehensive database of gene and protein interactions. • FBgn0011291 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34293
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21885 Dere\GG24011 Dgri\GH25071 Dmoj\GI18207 Dper\GL19212 Dpse\GA17941 Dsec\GM12298 Dsim\GD22339 Dvir\GJ14786 Dwil\GK24821 Dyak\GE10358
Curated drosophilid orthologs	Dpse\GA17941
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010019-PA Aedes aegypti (mosquito) AAEL014850-PA Aedes aegypti (mosquito) AGAP005522-PA Anopheles gambiae (mosquito) XP_394618.2 Apis mellifera (honey bee) XP_001952262.1 Acyrthosiphon pisum (pea aphid) At4g20280.1 Arabidopsis thaliana (wall cress) 90778 Batrachochytrium dendrobatidis (chytrid fungus) 223882 Branchiostoma floridae (lancelet) 223940 Branchiostoma floridae (lancelet) ENSBTAP00000022463 Bos taurus (bovine) CN17083 Caenorhabditis brenneri (small nematode) CBP05605 Caenorhabditis briggsae (nematode) CE07258 Caenorhabditis elegans (worm) ENSCAFP00000001780 Canis familiaris (dog) cn03334 Cryptococcus neoformans (yeast-like fungus) CPIJ005672 Culex pipens (mosquito) ENSCPOP00000013911 Cavia porcellus (guinea pig) RP29214 Caenorhabditis remanei (nematode) 182628 Capitella spl (polychaete worm) DEHA2E06160g Debaryomyces Hansenii (yeast) ENSDARP00000055151 Danio rerio (zebra fish) ENSECAP00000014380 Equus caballus (horse) ENSGACP00000004285 Gymnopilus aculeatus (mushroom) ENSGALP00000004305 Gallus gallus (chicken) 108569 Hypsipyla robusta (cedar shoot borer) ENSP00000354633 Homo sapiens (human) ISCW014707-PA Ixodes scapularis (deer tick) 133658 Lottia gigantea (owl limpet) ENSMODP00000017354 Monodelphis domestica (gray opossum) ENSMMUP00000028596 Macaca mulatta (rhesus monkey) ENSMUSP00000110498 Mus musculus (house mouse) 138459 Nematostella vectensis (starlet anemone) ENSOANP00000021125 Ornithorynchus anatinus (platypus) ENSORLP00000016459 Oryzias latipes (japanese killifish) LOC_Os01g48810.1 Oryza sativa (asian rice) 15516 Ostreococcus tauri (green alga) PHUM002816-PA Pediculus humanus (human body louse) ENSPPYP00000018476 Pongo pygmaeus (orangutan) 137221 Phytophthora sojae (root rot pathogen) 179507 Populus trichocarpa (black cottonwood) ENSPTRP00000030871 Pan troglodytes (chimpanzee) ENSRNOP00000000260 Rattus norvegicus (norway rat) 5036436 Sorghum bicolor (sorghum) Smp_134790 Schistosoma mansoni (trematode parasite) SPAC1002.04c Schizosaccharomyces pombe (fission yeast) 52029 Trichoplax adhaerens (metazoa) XP_966985.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015549 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027421 Takifugu rubripes (pufferfish Takifugu) YALI0E17809g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17477 LH16436 ISCW014707 FBgn0228225 FBgn0226780 FBgn0201990 FBgn0193746 FBgn0167235 JGI_V11_100237 JGI_V11_47763 FBgn0077950 FBgn0156811 FBgn0140946 FBgn0132526 FBgn0116150 FBgn0098885 CPIJ005672 BGIBMGA008893 ACYPI006026 GB12305 AGAP005522 AAEL014850 AAEL010019 PHUM581970 GLEAN_03938
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	29270 w1118; Mi{ET1}Taf11MB11995
VDRC	v104017 P{KK107818}VIE-260B v30442 w1118; P{GD4059}v30442
Genomic Clones ( 1 )
	BACR02I05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 6 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP03430
Other clones	FI15907
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	CK01.10B.G3 EC252929 EK169105 EP13649
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011291 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34293
Antibody Information
	polyclonal (Yokomori et al., 1993)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Marr et al., 2006) The proteins encoded by Tbp, Taf1, Taf2 and Taf11 are likely peripheral subunits of TFIID. (Wright et al., 2006) Identified with: LP03430 <up>FlyBase curator comment: EST subsequently found to be chimeric</up>. (BDGP Project Members, 2000-) Does not interact, in vitro, with human thryroid-hormone receptor-β. (Petty et al., 1996) The assembly and purification of various functional Tbp TAF complexes demonstrate that Tbp plus the TAFs is sufficient to replace endogenous TFIID to support activated transcription in vitro. (Chen et al., 1994) Taf12 and Taf11 join the TfIID complex through interaction with one or more of the larger subunits and only Taf12 may be in contact with Tbp. (Yokomori et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_164871 RefSeq (Proteins) • NP_723484 DDBJ / EMBL / GenBank • AAB19245 AAB29541 AAF52806 AI259909 BT003563 CZ469262 S67660 U06457 Entrez Gene - A searchable database of RefSeq genes. • 34293 UniProtKB/Swiss-Prot • P49906
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • TAFII28-like protein (IPR006809) Histone-fold (IPR009072)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60390 DroID - A comprehensive database of gene and protein interactions. • FBgn0011291 DRSC - Results from RNAi screens. • FBgn0011291 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011291 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4079-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011291 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34293 InParanoid A subset of ortholog calls from InParanoid. • AAEL010019-PA Aedes aegypti (mosquito) AAEL014850-PA Aedes aegypti (mosquito) AGAP005522-PA Anopheles gambiae (mosquito) XP_394618.2 Apis mellifera (honey bee) XP_001952262.1 Acyrthosiphon pisum (pea aphid) At4g20280.1 Arabidopsis thaliana (wall cress) 90778 Batrachochytrium dendrobatidis (chytrid fungus) 223882 Branchiostoma floridae (lancelet) 223940 Branchiostoma floridae (lancelet) ENSBTAP00000022463 Bos taurus (bovine) CN17083 Caenorhabditis brenneri (small nematode) CBP05605 Caenorhabditis briggsae (nematode) CE07258 Caenorhabditis elegans (worm) ENSCAFP00000001780 Canis familiaris (dog) cn03334 Cryptococcus neoformans (yeast-like fungus) CPIJ005672 Culex pipens (mosquito) ENSCPOP00000013911 Cavia porcellus (guinea pig) RP29214 Caenorhabditis remanei (nematode) 182628 Capitella spl (polychaete worm) DEHA2E06160g Debaryomyces Hansenii (yeast) ENSDARP00000055151 Danio rerio (zebra fish) ENSECAP00000014380 Equus caballus (horse) ENSGACP00000004285 Gymnopilus aculeatus (mushroom) ENSGALP00000004305 Gallus gallus (chicken) 108569 Hypsipyla robusta (cedar shoot borer) ENSP00000354633 Homo sapiens (human) ISCW014707-PA Ixodes scapularis (deer tick) 133658 Lottia gigantea (owl limpet) ENSMODP00000017354 Monodelphis domestica (gray opossum) ENSMMUP00000028596 Macaca mulatta (rhesus monkey) ENSMUSP00000110498 Mus musculus (house mouse) 138459 Nematostella vectensis (starlet anemone) ENSOANP00000021125 Ornithorynchus anatinus (platypus) ENSORLP00000016459 Oryzias latipes (japanese killifish) LOC_Os01g48810.1 Oryza sativa (asian rice) 15516 Ostreococcus tauri (green alga) PHUM002816-PA Pediculus humanus (human body louse) ENSPPYP00000018476 Pongo pygmaeus (orangutan) 137221 Phytophthora sojae (root rot pathogen) 179507 Populus trichocarpa (black cottonwood) ENSPTRP00000030871 Pan troglodytes (chimpanzee) ENSRNOP00000000260 Rattus norvegicus (norway rat) 5036436 Sorghum bicolor (sorghum) Smp_134790 Schistosoma mansoni (trematode parasite) SPAC1002.04c Schizosaccharomyces pombe (fission yeast) 52029 Trichoplax adhaerens (metazoa) XP_966985.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015549 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027421 Takifugu rubripes (pufferfish Takifugu) YALI0E17809g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34293 modMine - Data generated by the modENCODE project. • FBgn0011291 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17477 LH16436 ISCW014707 FBgn0228225 FBgn0226780 FBgn0201990 FBgn0193746 FBgn0167235 JGI_V11_100237 JGI_V11_47763 FBgn0077950 FBgn0156811 FBgn0140946 FBgn0132526 FBgn0116150 FBgn0098885 CPIJ005672 BGIBMGA008893 ACYPI006026 GB12305 AGAP005522 AAEL014850 AAEL010019 PHUM581970 GLEAN_03938
Synonyms & Secondary IDs ( 23 )
Reported As
Symbol Synonym	CG4079 (Aoyagi and Wassarman, 2000, Keleman et al., 2009.8.5) d30β (Pugh, 2000) dTAFII30 (Mantovani, 1999, Burke and Kadonaga, 1997) dTAFII30β (Gangloff et al., 2001, Veenstra and Wolffe, 2001, Lively et al., 2001, Cutforth and Gaul, 1999, Zhou et al., 1998, Goodrich and Tjian, 1994, Wright et al., 2006) dTAFII30 (Deak et al., 1997) dTAFII30 beta (Yokomori, 1994.2.25) dTAFII30β (Saurin et al., 2001) TAF (Mueller and Tora, 2004) TAF11 (Tora, 2002, Marr et al., 2006, Wright et al., 2006, Wright and Tjian, 2009, Weake et al., 2009, Santoso and Kadonaga, 2006) Taf11   TAF30b (Hansen et al., 1997) TAF30β (Green, 2000) Taf30β (Bell and Tora, 1999, Struhl and Moqtaderi, 1998, Verrijzer et al., 1995, Hori and Carey, 1994, Yokomori et al., 1993, Hoey et al., 1993, ) TAFII (Arnosti, 2002) TAFII30β (Tora, 2002, Wassarman and Sauer, 2001, Adams et al., 2000, Shen et al., 1998, Pham et al., 1999, Tansey and Herr, 1997) TafII30β (Chen et al., 1994) TAFII30β (Kennett et al., 2002) TFIID (Butler and Kadonaga, 2002, Hochheimer et al., 2002, Gu et al., 2002, Stathopoulos and Levine, 2002, Mizuguchi et al., 2001) TFIID 28 beta (Nakatani, 1994.2.8) TFIID-p28beta
Name Synonym	TBP-associated factor (Schuettengruber, 2006) TBP-associated factor 11   TBP-associated factor 30kD subunit β
Secondary FlyBase IDs
References ( 61 )
Generate a list of	All references relating to this gene ( 61 )
List References by type	Research paper  ( 24 ) Supplementary material  ( 3 ) Review  ( 18 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 2 ) Computer file  ( 3 ) Protein sequence record  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
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Recent reviews (0)
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