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Gene Dmel\Taf11

General Information
Symbol	Dmel\Taf11	Species	D. melanogaster
Name	TBP-associated factor 11	Annotation symbol	CG4079
Feature type	protein_coding_gene	FlyBase ID	FBgn0011291
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	dTAFII30β, TAF30β, TAFII30β, TAF11, TFIID, dTAFII30
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	30C7-30C7	Sequence location	2L:9,762,424..9,763,262 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene TBP-associated factor 11 is referred to in FlyBase by the symbol Dmel\Taf11 (CG4079, FBgn0011291). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: transcription factor binding; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly. Based on sequence similarity, it is predicted to be involved in the biological process: transcription initiation from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Histone-fold; TAFII28-like protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1636486_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Taf11. Gene sequence location is 2L:9762424..9763262.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 30C7-30C7   Limits computationally determined from genome sequence between P{lacW}zf30Ck02506&P{EP}undEP424 and P{lacW}l(2)k06416k06416&P{lacW}sopk04603
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Taf11 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Taf11-RA FBtr0079924  NM_164871   777   196
Additional Transcript Data & Comments
Reported size (kB)	0.75 (longest cDNA) (Yokomori et al., 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Taf11-PA   FBpp0079514   22.1   196   4.59     NP_723484   AAF52806
Additional Polypeptide Data & Comments
Reported size (kDa)	196 (aa); 22 (kD predicted) (Yokomori et al., 1993)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • TAFII28-like protein (IPR006809) Histone-fold (IPR009072)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52806   AI259909   BT132724   CO285491   CO342028   CZ469262   EC229052   EC252929   S67660 AAB29541   U06457 AAB19245
UniProtKB/Swiss-Prot	P49906
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
nucleus inferred from direct assay (Yokomori et al., 1993) transcription factor TFIID complex inferred from direct assay (Yokomori et al., 1993)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    188.525 Larval Midgut    68.4 Larval Hindgut    83.9 Larval Malpighian Tubules    109.7 Larval Fat Body    85 Larval Salivary Gland    186.7 Larval Trachea    148.575 Larval Carcass    99.525 Adult Head    70.3 Adult Eye    102.6 Adult Brain    118 Adult Thoracic-Abdominal Ganglion    107.7 Adult Crop    94 Adult Midgut    79.2 Adult Hindgut    81.3 Adult Malpighian Tubules    60.1 Adult Fat Body    68.9 Adult Salivary Gland    127.9 Adult Heart    82.575 Adult VirginFemale Spermatheca    74.2 Adult InseminatedFemale Spermatheca    87.7 Adult Ovary    209.9 Adult Testis    66.5 Adult Male Accessory Gland    157.3 Adult Carcass    64.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    70.3   NA  Eye    102.6   NA  Brain    118   188.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    107.7   NA  Crop    94   68.4  Midgut    79.2   83.9  Hindgut    81.3   109.7  Malpighian Tubules    60.1   85  Fat Body    68.9   186.7  Salivary Gland    127.9   NA  Heart    82.575   148.575  Trachea    NA   NA  VirginFemale Spermatheca    74.2   NA  InseminatedFemale Spermatheca    87.7   NA  Ovary    209.9   NA  Testis    66.5   NA  Male Accessory Gland    157.3   99.525  Carcass    64.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3  (35) central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female  (29) ovary, mated 4-day female  (35) testis, mated 4-day male  (27) accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3  (35) central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female  29 ovary, mated 4-day female  (35) testis, mated 4-day male  27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    35 central nervous system, pupae P8    18 head, virgin 1-day female    9 head, virgin 4-day female    10 head, virgin 20-day female    5 head, mated 1-day female    11 head, mated 4-day female    9 head, mated 20-day female    7 head, mated 1-day male    10 head, mated 4-day male    13 head, mated 20-day male    13 salivary gland, larvae L3 wandering    24 salivary gland, white prepupae    20 digestive system, larvae L3 wandering    19 digestive system, 1-day adult    10 digestive system, 4-day adult    12 digestive system, 20-day adult    10 fat body, larvae L3 wandering    5 fat body, white prepupae    16 fat body, pupae P8    19 carcass, larvae L3 wandering    23 carcass, 1-day adult    7 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    29 ovary, mated 4-day female    35 testis, mated 4-day male    27 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  (41) embryo 04-06hr  (30) embryo 06-08hr  (43) embryo 08-10hr  (44) embryo 10-12hr  (43) embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  (41) embryo 04-06hr  30 embryo 06-08hr  (43) embryo 08-10hr  (44) embryo 10-12hr  (43) embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    41 embryo 04-06hr    30 embryo 06-08hr    43 embryo 08-10hr    44 embryo 10-12hr    43 embryo 12-14hr    25 embryo 14-16hr    19 embryo 16-18hr    13 embryo 18-20hr    10 embryo 20-22hr    14 embryo 22-24hr    14 larva L1    10 larva L2    10 larva L3 12hr old    10 larva L3 puffstage 1-2    9 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    18 white prepupae new    19 white prepupae 12hr    20 white prepupae 24hr    25 pupae 2d postWPP    16 pupae 3d postWPP    8 pupae 4d postWPP    7 adult male 01day    6 adult male 05day    8 adult male 30day    7 adult female 01day    14 adult female 05day    22 adult female 30day    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1    112 embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  26 embryonic 1182-4H  (42) embryonic GM2    21 embryonic Kc167    17 embryonic S1  (112) embryonic S3  (47) leg disc CME L1  (31) wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (46) wing disc ML-DmD21  (92) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  (57) eye-antennal disc ML-DmD11  (47) antennal disc ML-DmD20-c5  (43) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (45) CNS ML-DmBG2-c2  (32) tumorous blood cells mbn2    22 ovary fGS/OSS  (33) ovary OSC  (50) ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1  (112) embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1    112 embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1    112 embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  26 embryonic 1182-4H  (42) embryonic GM2    21 embryonic Kc167    17 embryonic S1  (112) embryonic S3  (47) leg disc CME L1  31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (46) wing disc ML-DmD21  (92) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  (57) eye-antennal disc ML-DmD11  (47) antennal disc ML-DmD20-c5  (43) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (45) CNS ML-DmBG2-c2  32 tumorous blood cells mbn2    22 ovary fGS/OSS  (33) ovary OSC  (50) ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1  112 embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    26 embryonic 1182-4H    42 embryonic GM2    21 embryonic Kc167    17 embryonic S1    112 embryonic S3    47 leg disc CME L1    31 wing disc CME-W2    18 wing disc ML-DmD8    20 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    46 wing disc ML-DmD21    92 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    57 eye-antennal disc ML-DmD11    47 antennal disc ML-DmD20-c5    43 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    32 tumorous blood cells mbn2    22 ovary fGS/OSS    33 ovary OSC    50 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (29) cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult  (30) Copper 0.5 mM 12 hrs, larvae L3  (28) Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (30) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult  30 Copper 0.5 mM 12 hrs, larvae L3  28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    13 heat shock, 4-day adult    15 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    16 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    28 Copper 15 mM 48 hrs, 4-day adult    14 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    10 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    9 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    30 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    19 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    13 Rotenone 8 μg 12 hrs, larvae L3    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011291 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4079-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Taf11GD4059 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Taf11 Class Mutagen Stocks Known lesion Taf11MB11995 1 -- Taf11c04450 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Taf11 Class Mutagen Stocks Known lesion Taf11GD4059 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf11KK107818 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Taf11dsRNA.cWa in vitro construct - RNAi 0 Yes Taf11t4.3 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6024 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4059} NA P{KK107818} NA characterization construct P{und+t4.3} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}Taf11c04450 NA insertion of enhancer trap binary system Mi{ET1}Taf11MB11995 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
contributes_to RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly inferred from direct assay (Yokomori et al., 1993) transcription factor binding inferred from physical interaction with Taf1 (Yokomori et al., 1993) inferred from physical interaction with Taf2 (Yokomori et al., 1993)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Yokomori et al., 1993) transcription factor TFIID complex inferred from direct assay (Yokomori et al., 1993)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
protein heterodimerization activity inferred from electronic annotation with InterPro:IPR009072 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription initiation from RNA polymerase II promoter inferred from sequence or structural similarity with human TAF11 AND inferred from sequence or structural similarity with Saccharomyces TAF40 (Aoyagi and Wassarman, 2000)
Cellular Component
CV term Evidence References
nucleus non-traceable author statement (Swiss-Prot Project Members, 1996.6.1) transcription factor TFIID complex inferred from sequence or structural similarity with human TAF11 AND inferred from sequence or structural similarity with Saccharomyces TAF40 (Aoyagi and Wassarman, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Taf11 - Or49b anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Taf11 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60390 DroID - A comprehensive database of gene and protein interactions. • FBgn0011291 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34293
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6C5D51 Dipteran inclusive ortholog search EOG6614DC Insect inclusive ortholog search EOG63JB29 Arthropod inclusive ortholog search EOG6HHMJZ Metazoa inclusive ortholog search EOG6MH53H
Orthologs in Drosophila Species (EOG6C5D51)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Taf11     Drosophila simulans   Dsim\GD22339 Y   Drosophila sechellia   Dsec\GM12298 Y   Drosophila erecta   Dere\GG24011 Y   Drosophila yakuba   Dyak\GE10358 Y   Drosophila ananassae   Dana\GF21885 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17941 Y   Drosophila persimilis   Dper\GL19212 Y   Drosophila willistoni   Dwil\GK24821 Y   Drosophila virilis   Dvir\GJ14786 Y   Drosophila mojavensis   Dmoj\GI18207 Y   Drosophila grimshawi   Dgri\GH25071 Y
Orthologs in non-Drosophila Dipterans (EOG6614DC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010019   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014850   Anopheles gambiae Malaria mosquito  Agam\AGAP005522   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005672
Orthologs in non-Dipteran Insects (EOG63JB29)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Taf11   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003952   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16225   Atta cephalotes Leafcutter ant  Acep\ACEP16705   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15898   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14152   Linepithema humile Argentine ant  Lhum\LH16436   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17477   Solenopsis invicta Red fire ant  Sinv\SINV17324   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006026   Bombyx mori Silkmoth  Bmor\BGIBMGA008893   Pediculus humanus Human body louse  Phum\PHUM581970   Tribolium castaneum Red flour beetle  Tcas\TC003938
Orthologs in non-Insect Arthropods (EOG6HHMJZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Abd-B   Daphnia pulex Water flea  Dpux\ZNF710   Ixodes scapularis Deer tick  Isca\ISCW014707
Orthologs in non-Arthropod Metazoa (EOG6MH53H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\taf-11.2   Caenorhabditis elegans Nematode  Cele\taf-11.1   Caenorhabditis elegans Nematode  Cele\taf-11.3   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008669gn   Danio rerio Zebrafish  Drer\taf11   Xenopus tropicalis Western clawed frog  Xtro\taf11   Gallus gallus Domestic chicken  Ggal\TAF11   Mus musculus House mouse  Mmus\Taf11   Rattus norvegicus Norway rat  Rnor\Taf11   Homo sapiens Human  Hsap\TAF11
Human Orthologs (1)
Gene OMIM HGNC Hsap\TAF11
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22339 Drosophila sechellia Dsec\GM12298 Drosophila erecta Dere\GG24011 Drosophila yakuba Dyak\GE10358 Drosophila ananassae Dana\GF21885 Drosophila pseudoobscura pseudoobscura Dpse\GA17941 Drosophila persimilis Dper\GL19212 Drosophila willistoni Dwil\GK24821 Drosophila virilis Dvir\GJ14786 Drosophila mojavensis Dmoj\GI18207 Drosophila grimshawi Dgri\GH25071
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	29270 w1118; Mi{ET1}Taf11MB11995
VDRC	v104017 P{KK107818}VIE-260B v30442 w1118; P{GD4059}v30442
Genomic Clones ( 1 )
	BACR02I05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 6 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP03430
Other clones	FI15907
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	CK01.10B.G3 EC252929 EK169105 EP13649
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011291 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34293
Antibody Information
	polyclonal (Yokomori et al., 1993)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Marr et al., 2006) The proteins encoded by Tbp, Taf1, Taf2 and Taf11 are likely peripheral subunits of TFIID. (Wright et al., 2006) Identified with: LP03430 <up>FlyBase curator comment: EST subsequently found to be chimeric</up>. (BDGP Project Members, 2000-) Does not interact, in vitro, with human thryroid-hormone receptor-β. (Petty et al., 1996) The assembly and purification of various functional Tbp TAF complexes demonstrate that Tbp plus the TAFs is sufficient to replace endogenous TFIID to support activated transcription in vitro. (Chen et al., 1994) Taf12 and Taf11 join the TfIID complex through interaction with one or more of the larger subunits and only Taf12 may be in contact with Tbp. (Yokomori et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_164871 RefSeq (Proteins) • NP_723484 DDBJ / EMBL / GenBank • AAB19245 AAB29541 AAF52806 AI259909 BT003563 CZ469262 S67660 U06457 Entrez Gene - A searchable database of RefSeq genes. • 34293 UniProtKB/Swiss-Prot • P49906
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • TAFII28-like protein (IPR006809) Histone-fold (IPR009072)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60390 DroID - A comprehensive database of gene and protein interactions. • FBgn0011291 DRSC - Results from RNAi screens. • FBgn0011291 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011291 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4079-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011291 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34293 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34293 modMine - Data generated by the modENCODE project. • FBgn0011291
Synonyms & Secondary IDs ( 23 )
Reported As
Symbol Synonym	CG4079 (Aoyagi and Wassarman, 2000, Keleman et al., 2009.8.5) d30β (Pugh, 2000) dTAFII30 (Mantovani, 1999, Burke and Kadonaga, 1997) dTAFII30β (Gangloff et al., 2001, Veenstra and Wolffe, 2001, Lively et al., 2001, Cutforth and Gaul, 1999, Zhou et al., 1998, Goodrich and Tjian, 1994, Wright et al., 2006) dTAFII30 (Deak et al., 1997) dTAFII30 beta (Yokomori, 1994.2.25) dTAFII30β (Saurin et al., 2001) TAF (Mueller and Tora, 2004) TAF11 (Tora, 2002, Marr et al., 2006, Wright et al., 2006, Wright and Tjian, 2009, Weake et al., 2009, Santoso and Kadonaga, 2006) Taf11   TAF30b (Hansen et al., 1997) TAF30β (Green, 2000) Taf30β (Bell and Tora, 1999, Struhl and Moqtaderi, 1998, Verrijzer et al., 1995, Hori and Carey, 1994, Yokomori et al., 1993, Hoey et al., 1993, ) TAFII (Arnosti, 2002) TAFII30β (Tora, 2002, Wassarman and Sauer, 2001, Adams et al., 2000, Shen et al., 1998, Pham et al., 1999, Tansey and Herr, 1997) TafII30β (Chen et al., 1994) TAFII30β (Kennett et al., 2002) TFIID (Butler and Kadonaga, 2002, Hochheimer et al., 2002, Gu et al., 2002, Stathopoulos and Levine, 2002, Mizuguchi et al., 2001) TFIID 28 beta (Nakatani, 1994.2.8) TFIID-p28beta
Name Synonym	TBP-associated factor (Schuettengruber et al., 2007) TBP-associated factor 11   TBP-associated factor 30kD subunit β
Secondary FlyBase IDs
References ( 63 )
Generate a list of	All references relating to this gene ( 63 )
List References by type	Research paper  ( 24 ) Supplementary material  ( 4 ) Review  ( 18 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 2 ) Protein sequence record  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...
Recent reviews (0)
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