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Gene Dmel\OstStt3

General Information
Symbol	Dmel\OstStt3	Species	D. melanogaster
Name	Oligosaccharyl transferase 3	Annotation symbol	CG7748
Feature type	protein_coding_gene	FlyBase ID	FBgn0011336
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	l(3)j2D9
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96B19-96B20	Sequence location	3R:20,892,434..20,895,372 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Oligosaccharyl transferase 3 is referred to in FlyBase by the symbol Dmel\OstStt3 (CG7748, FBgn0011336). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oligosaccharyl transferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein glycosylation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Oligosaccharyl transferase, STT3 subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult heart, adult ovary, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1631240_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of OstStt3. Gene sequence location is 3R:20892434..20895372.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features HFA16781 BKN21409
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96B19-96B20   Limits computationally determined from genome sequence between P{PZ}ssh01207 and P{lacW}OstStt3j2D9
Experimentally Determined Cytological Location
Cytogenetic map Notes References 96B19-96B20   (determined by in situ hybridisation)   (Spradling et al., 1999) 96B19-96B20     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\OstStt3 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) OstStt3-RA FBtr0084786  NM_079770   2716   774
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein OstStt3-PA   FBpp0084161   87.6   774   9.27     NP_524494   AAF56391
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Oligosaccharyl transferase, STT3 subunit (IPR003674)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA694951   AA949890   AE014297 AAF56391   AF132552 AAD27851   AI107144   AI133998   AI135629   AI257750   AI295381   AI297771   AI513252   AI514952   AI531138   AI532108   AI533035   AI533215   AI542327   AQ026308   AX799088   BF486090   BF489372   BF496296   BF502026   BF502679   BF503420   BF504378   BF506253   BG636414   BG640860   BG641064   BG641172   BI162865   BI163592   BI166509   BI167839   BI168455   BI170396   BI170481   BI171940   BI172808   BI173041   BI173583   BI227902   BI237763   BI242003   BI354111   BI357074   BI362994   BI363168   BI364613   BI364972   BI370013   BI373819   BI374189   BI374334   BI484774   BI579570   BI586931   BI632973   BI635692   BP550015   CK657451   CK657649   CK659033   CK659064   CK659968   CO182924   CO194814   CO270232   CO273325   CO278537   CO284658   CO295419   CO295609   CO295621   CO296113   CO304185   CO312883   CO319309   CO321157   CO330260   CO337666   CO341294   CO341542   CZ469647   CZ481465   DN154327   DQ507309   EC059386   EC064073   EC074032   EC076510   EC083968   EC195019   EC198666   EC201931   EC216272   EC220812   EC221600   EC224746   EC231374   EC235995   EC237049   EC238052   EC238884   EC240821   EC252202   EC255950   EC263407   EL871090   EL871091   EL871207   EL871208   EL871325   EL871326   EL871442   EL871443   EL876366   EL876367   ES691237   ES694676   EV599488
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KN63 Q9XZ53
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage | male     (Arbeitman et al., 2004)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0011336    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0011336 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0011336 expression level Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr    14079 embryo 06-08hr    12079 embryo 08-10hr    9753 embryo 10-12hr    11026 embryo 12-14hr    10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2    12399 larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4182) embryo 02-04hr  (7095) embryo 04-06hr  (14079) embryo 06-08hr  (12079) embryo 08-10hr  (9753) embryo 10-12hr  (11026) embryo 12-14hr  (10127) embryo 14-16hr  (9695) embryo 16-18hr  (7087) embryo 18-20hr  (4569) embryo 20-22hr  (1994) embryo 22-24hr  (1915) larva L1  (6026) larva L2  (12399) larva L3 12hr old  (8801) larva L3 puffstage 1-2  (6435) larva L3 puffstage 3-6  (6173) larva L3 puffstage 7-9  (6449) white prepupae new  (7346) white prepupae 12hr  (3420) white prepupae 24hr  (5800) pupae 2d postWPP  (4561) pupae 3d postWPP  (3021) pupae 4d postWPP  (2988) adult male 01day  (5631) adult male 05day  (6440) adult male 30day  (7879) adult female 01day  (5628) adult female 05day  (5945) adult female 30day  (5568) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4182) embryo 02-04hr  (7095) embryo 04-06hr  (14079) embryo 06-08hr  (12079) embryo 08-10hr  (9753) embryo 10-12hr  (11026) embryo 12-14hr  (10127) embryo 14-16hr  (9695) embryo 16-18hr  (7087) embryo 18-20hr  (4569) embryo 20-22hr  (1994) embryo 22-24hr  (1915) larva L1  (6026) larva L2  (12399) larva L3 12hr old  (8801) larva L3 puffstage 1-2  (6435) larva L3 puffstage 3-6  (6173) larva L3 puffstage 7-9  (6449) white prepupae new  (7346) white prepupae 12hr  (3420) white prepupae 24hr  (5800) pupae 2d postWPP  (4561) pupae 3d postWPP  (3021) pupae 4d postWPP  (2988) adult male 01day  (5631) adult male 05day  (6440) adult male 30day  (7879) adult female 01day  (5628) adult female 05day  (5945) adult female 30day  (5568) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr  (14079) embryo 06-08hr  (12079) embryo 08-10hr    9753 embryo 10-12hr  (11026) embryo 12-14hr  10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2  (12399) larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr    14079 embryo 06-08hr    12079 embryo 08-10hr    9753 embryo 10-12hr    11026 embryo 12-14hr    10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2    12399 larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0011336 expression level Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr    14079 embryo 06-08hr    12079 embryo 08-10hr    9753 embryo 10-12hr    11026 embryo 12-14hr    10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2    12399 larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4182) embryo 02-04hr  (7095) embryo 04-06hr  (14079) embryo 06-08hr  (12079) embryo 08-10hr  (9753) embryo 10-12hr  (11026) embryo 12-14hr  (10127) embryo 14-16hr  (9695) embryo 16-18hr  (7087) embryo 18-20hr  (4569) embryo 20-22hr  (1994) embryo 22-24hr  (1915) larva L1  (6026) larva L2  (12399) larva L3 12hr old  (8801) larva L3 puffstage 1-2  (6435) larva L3 puffstage 3-6  (6173) larva L3 puffstage 7-9  (6449) white prepupae new  (7346) white prepupae 12hr  (3420) white prepupae 24hr  (5800) pupae 2d postWPP  (4561) pupae 3d postWPP  (3021) pupae 4d postWPP  (2988) adult male 01day  (5631) adult male 05day  (6440) adult male 30day  (7879) adult female 01day  (5628) adult female 05day  (5945) adult female 30day  (5568) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4182) embryo 02-04hr  (7095) embryo 04-06hr  (14079) embryo 06-08hr  (12079) embryo 08-10hr  (9753) embryo 10-12hr  (11026) embryo 12-14hr  (10127) embryo 14-16hr  (9695) embryo 16-18hr  (7087) embryo 18-20hr  (4569) embryo 20-22hr  1994 embryo 22-24hr  1915 larva L1  (6026) larva L2  (12399) larva L3 12hr old  (8801) larva L3 puffstage 1-2  (6435) larva L3 puffstage 3-6  (6173) larva L3 puffstage 7-9  (6449) white prepupae new  (7346) white prepupae 12hr  (3420) white prepupae 24hr  (5800) pupae 2d postWPP  (4561) pupae 3d postWPP  (3021) pupae 4d postWPP  (2988) adult male 01day  (5631) adult male 05day  (6440) adult male 30day  (7879) adult female 01day  (5628) adult female 05day  (5945) adult female 30day  (5568) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr  14079 embryo 06-08hr  12079 embryo 08-10hr    9753 embryo 10-12hr  11026 embryo 12-14hr  10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2  12399 larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4182 embryo 02-04hr    7095 embryo 04-06hr    14079 embryo 06-08hr    12079 embryo 08-10hr    9753 embryo 10-12hr    11026 embryo 12-14hr    10127 embryo 14-16hr    9695 embryo 16-18hr    7087 embryo 18-20hr    4569 embryo 20-22hr    1994 embryo 22-24hr    1915 larva L1    6026 larva L2    12399 larva L3 12hr old    8801 larva L3 puffstage 1-2    6435 larva L3 puffstage 3-6    6173 larva L3 puffstage 7-9    6449 white prepupae new    7346 white prepupae 12hr    3420 white prepupae 24hr    5800 pupae 2d postWPP    4561 pupae 3d postWPP    3021 pupae 4d postWPP    2988 adult male 01day    5631 adult male 05day    6440 adult male 30day    7879 adult female 01day    5628 adult female 05day    5945 adult female 30day    5568 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0011336    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0011336 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult hindgut, adult heart, adult ovary, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0011336 expression level Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland    3337.6 Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland    3377.3 Adult Heart    495.45 Adult VirginFemale Spermatheca    1961.7 Adult InseminatedFemale Spermatheca    1983.7 Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland    4516.6 Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (653.875) Larval Midgut  (641) Larval Hindgut  (666) Larval Malpighian Tubules  (548.8) Larval Fat Body  (759.1) Larval Salivary Gland  (3337.6) Larval Trachea  (844.675) Larval Carcass  (743.05) Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut  (711.4) Adult Hindgut    448.9 Adult Malpighian Tubules  (883) Adult Fat Body  (708.9) Adult Salivary Gland  (3377.3) Adult Heart    495.45 Adult VirginFemale Spermatheca  (1961.7) Adult InseminatedFemale Spermatheca  (1983.7) Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland  (4516.6) Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland  (3337.6) Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland  (3377.3) Adult Heart    495.45 Adult VirginFemale Spermatheca  (1961.7) Adult InseminatedFemale Spermatheca  (1983.7) Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland  (4516.6) Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland    3337.6 Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland    3377.3 Adult Heart    495.45 Adult VirginFemale Spermatheca    1961.7 Adult InseminatedFemale Spermatheca    1983.7 Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland    4516.6 Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0011336 expression level Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland    3337.6 Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland    3377.3 Adult Heart    495.45 Adult VirginFemale Spermatheca    1961.7 Adult InseminatedFemale Spermatheca    1983.7 Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland    4516.6 Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  653.875 Larval Midgut  641 Larval Hindgut  666 Larval Malpighian Tubules  548.8 Larval Fat Body  759.1 Larval Salivary Gland  (3337.6) Larval Trachea  (844.675) Larval Carcass  743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut  711.4 Adult Hindgut    448.9 Adult Malpighian Tubules  (883) Adult Fat Body  708.9 Adult Salivary Gland  (3377.3) Adult Heart    495.45 Adult VirginFemale Spermatheca  (1961.7) Adult InseminatedFemale Spermatheca  (1983.7) Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland  (4516.6) Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland  (3337.6) Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland  (3377.3) Adult Heart    495.45 Adult VirginFemale Spermatheca  (1961.7) Adult InseminatedFemale Spermatheca  (1983.7) Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland  (4516.6) Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    653.875 Larval Midgut    641 Larval Hindgut    666 Larval Malpighian Tubules    548.8 Larval Fat Body    759.1 Larval Salivary Gland    3337.6 Larval Trachea    844.675 Larval Carcass    743.05 Adult Head    420.9 Adult Eye    331.575 Adult Brain    231.2 Adult Thoracic-Abdominal Ganglion    279.6 Adult Crop    390.7 Adult Midgut    711.4 Adult Hindgut    448.9 Adult Malpighian Tubules    883 Adult Fat Body    708.9 Adult Salivary Gland    3377.3 Adult Heart    495.45 Adult VirginFemale Spermatheca    1961.7 Adult InseminatedFemale Spermatheca    1983.7 Adult Ovary    362.8 Adult Testis    363.6 Adult Male Accessory Gland    4516.6 Adult Carcass    389.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    420.9   NA  Eye    331.575   NA  Brain    231.2   653.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    279.6   NA  Crop    390.7   641  Midgut    711.4   666  Hindgut    448.9   548.8  Malpighian Tubules    883   759.1  Fat Body    708.9   3337.6  Salivary Gland    3377.3   NA  Heart    495.45   844.675  Trachea    NA   NA  VirginFemale Spermatheca    1961.7   NA  InseminatedFemale Spermatheca    1983.7   NA  Ovary    362.8   NA  Testis    363.6   NA  Male Accessory Gland    4516.6   743.05  Carcass    389.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011336 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7748-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for OstStt3 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive OstStt3j2D9 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of OstStt3 Class Mutagen Stocks Known lesion OstStt3j2D9 P-element activity 2 -- OstStt3e03710 piggyBac transposase 1 -- OstStt3c04969 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of OstStt3 Class Mutagen Stocks Known lesion OstStt3GD261 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)BSC493 (Christensen et al., 2008.4.15) Df(3R)BSC494 (Christensen et al., 2008.4.15)
Not disrupted in	Df(3R)XTA1 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD261} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}OstStt3j2D9 No miscellaneous insertions PBac{PB}OstStt3c04969 NA PBac{RB}OstStt3e03710 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
oligosaccharyl transferase activity inferred from sequence or structural similarity (Spradling et al., 1999) inferred from sequence or structural similarity with Saccharomyces STT3 (FlyBase, 1992-)
Biological Process
CV term Evidence References
protein glycosylation inferred from electronic annotation with InterPro:IPR003674 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
oligosaccharyltransferase complex inferred from sequence or structural similarity (Spradling et al., 1999) inferred from sequence or structural similarity with Saccharomyces STT3 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions OstStt3 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67926 DroID - A comprehensive database of gene and protein interactions. • FBgn0011336 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43005
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17105 Dere\GG12291 Dgri\GH19585 Dmoj\GI23816 Dper\GL21896 Dsec\GM17756 Dsim\GD18237 Dvir\GJ23594 Dwil\GK13408 Dyak\GE10744
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002804-PA Aedes aegypti (mosquito) AGAP002396-PA Anopheles gambiae (mosquito) XP_001952466.1 Acyrthosiphon pisum (pea aphid) 10658 Batrachochytrium dendrobatidis (chytrid fungus) 125007 Branchiostoma floridae (lancelet) XP_001892857.1 Brugia malayi (roundworm nematode) BGIBMGA004898-PA Bombyx mori (silk worm) ENSBTAP00000009782 Bos taurus (bovine) CAL0004694 Candida albicans (a form of yeast) CN14117 Caenorhabditis brenneri (small nematode) CBP28785 Caenorhabditis briggsae (nematode) CE01395 Caenorhabditis elegans (worm) ENSCAFP00000008096 Canis familiaris (dog) CAGL0A00209g Candida glabrata (haploid yeast) ENSCINP00000003935 Ciona intestinalis (sea squirt) JA10210 Caenorhabditis japonica (nematode) cn08176 Cryptococcus neoformans (yeast-like fungus) CPIJ008679 Culex pipens (mosquito) ENSCPOP00000012894 Cavia porcellus (guinea pig) RP39491 Caenorhabditis remanei (nematode) ENSCSAVP00000018475 Ciona savignyi (sedentary tunicate) 179664 Capitella spl (polychaete worm) DEHA2B04554g Debaryomyces Hansenii (yeast) 307851 Daphnia pulex (daphnia) ENSDARP00000093301 Danio rerio (zebra fish) ENSECAP00000005358 Equus caballus (horse) ENSGACP00000004952 Gymnopilus aculeatus (mushroom) ENSGALP00000036887 Gallus gallus (chicken) 111950 Hypsipyla robusta (cedar shoot borer) ENSP00000295770 Homo sapiens (human) ISCW022325-PA Ixodes scapularis (deer tick) KLLA0C11627g Kluyveromyces lactis (yeast) 110908 Lottia gigantea (owl limpet) LmjF35.1130 Leishmania major (virus) ENSMMUP00000011289 Macaca mulatta (rhesus monkey) ENSMUSP00000035010 Mus musculus (house mouse) 238356 Nematostella vectensis (starlet anemone) XP_001601373.1 Nasonia vitripennis (wasp) ENSOANP00000003606 Ornithorynchus anatinus (platypus) ENSORLP00000005367 Oryzias latipes (japanese killifish) PHUM003715-PA Pediculus humanus (human body louse) PP09929 Pristionchus pacificus (nematode) ENSPPYP00000015716 Pongo pygmaeus (orangutan) ENSPTRP00000025378 Pan troglodytes (chimpanzee) ENSRNOP00000017243 Rattus norvegicus (norway rat) YGL022W Saccharomyces cerevisiae (budding yeast) Smp_158600 Schistosoma mansoni (trematode parasite) SPBC1271.02 Schizosaccharomyces pombe (fission yeast) XP_001181301.1 Strongylocentrotus purpuratus (purple sea urchin) 31147 Trichoplax adhaerens (metazoa) XP_972341.1 Tribolium castaneum (red flour beetle) Tc00.1047053505163.80 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009243 Tetraodon nigroviridis (green spotted pufferfish) 4160 Thalassiosira pseudonana (marine diatom) ENSTRUP00000033407 Takifugu rubripes (pufferfish Takifugu) YALI0B16434g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12469 NV15224 LH11924 ISCW022325 FBgn0228587 FBgn0215417 FBgn0210691 FBgn0189771 FBgn0172664 JGI_V11_307851 FBgn0243942 FBgn0159489 FBgn0146541 FBgn0127049 FBgn0104582 FBgn0094124 CPIJ008679 BGIBMGA004898 ACYPI004183 AGAP002396 AAEL015049 AAEL002804 PHUM459530 GLEAN_09183
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	10340 y1 w1118; P{lacW}OstStt3j2D9/TM3, Sb1
Harvard	- PBac{RB}OstStt3e03710
Kyoto	111054 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}82B P{lacW}OstStt3j2D9/TM6B, P{Car20y}TPN1, Tb1
Genomic Clones ( 2 )
	BACR03I15 BACR03L02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 105 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM01838
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05729 AT08682 AT10060 AT17637 AT18477 AT19406 AT20268 AT25369 GH06456 GH11327 GM26338 LD29946 LD46592 LP06212 LP08987 LP12143 LP16462 LP16523 LP18143 LP23759 LP24119 RE02124 RE03026 RE06659 RE08321 RE09187 RE11825 RE11944 RE13841 RE15488 RE15774 RE16531 RE25288 RE34052 RE39217 RE43425 RE47695 RE47920 RE49773 RE50181 RE56375 RE61243 RE61718 RE61893 RE67926 RE73627 RH27159 SD02056 SD03477 SD04713 SD04965 SD08615 SD12024 SD12296 SD12448 SD14123 SD17119 SD26885
Other clones	10696 15747 17602 19184 55573 77678 77736 80366 83906 105419 148767 173374 191905 214353.2 214481.1 298339 CK01.27A.H9 CK01.30D.E10 CK01.108C.F2 Dmel_neb_015916_0931_0655 EC24286 EC39267 EK097953 EK110521 EK130321 EK166513 EK209809 EK210936 EK210951 EK212733 EK218319 EK230463 EK244050 EK277613 EK290419 EK294830 EN15033 EP12164 EP12637 FGM104G09 GH13452 IP03243 IP03343 IP03443 IP03543 IP06251
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011336 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43005
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: OstStt3 anon-WO03054008.7 (FlyBase, 1996-)
Additional comments	Source for merge of OstStt3 anon-WO03054008.7 was sequence comparison (date:031211). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079770 RefSeq (Proteins) • NP_524494 DDBJ / EMBL / GenBank • AA694951 AAD27851 AAF56391 AF132552 AQ026308 AX799088 CZ469647 CZ481465 Entrez Gene - A searchable database of RefSeq genes. • 43005 UniProtKB/TrEMBL • Q7KN63 Q9XZ53
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Oligosaccharyl transferase, STT3 subunit (IPR003674)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67926 DroID - A comprehensive database of gene and protein interactions. • FBgn0011336 DRSC - Results from RNAi screens. • FBgn0011336 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011336 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7748-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011336 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43005 InParanoid A subset of ortholog calls from InParanoid. • AAEL002804-PA Aedes aegypti (mosquito) AGAP002396-PA Anopheles gambiae (mosquito) XP_001952466.1 Acyrthosiphon pisum (pea aphid) 10658 Batrachochytrium dendrobatidis (chytrid fungus) 125007 Branchiostoma floridae (lancelet) XP_001892857.1 Brugia malayi (roundworm nematode) BGIBMGA004898-PA Bombyx mori (silk worm) ENSBTAP00000009782 Bos taurus (bovine) CAL0004694 Candida albicans (a form of yeast) CN14117 Caenorhabditis brenneri (small nematode) CBP28785 Caenorhabditis briggsae (nematode) CE01395 Caenorhabditis elegans (worm) ENSCAFP00000008096 Canis familiaris (dog) CAGL0A00209g Candida glabrata (haploid yeast) ENSCINP00000003935 Ciona intestinalis (sea squirt) JA10210 Caenorhabditis japonica (nematode) cn08176 Cryptococcus neoformans (yeast-like fungus) CPIJ008679 Culex pipens (mosquito) ENSCPOP00000012894 Cavia porcellus (guinea pig) RP39491 Caenorhabditis remanei (nematode) ENSCSAVP00000018475 Ciona savignyi (sedentary tunicate) 179664 Capitella spl (polychaete worm) DEHA2B04554g Debaryomyces Hansenii (yeast) 307851 Daphnia pulex (daphnia) ENSDARP00000093301 Danio rerio (zebra fish) ENSECAP00000005358 Equus caballus (horse) ENSGACP00000004952 Gymnopilus aculeatus (mushroom) ENSGALP00000036887 Gallus gallus (chicken) 111950 Hypsipyla robusta (cedar shoot borer) ENSP00000295770 Homo sapiens (human) ISCW022325-PA Ixodes scapularis (deer tick) KLLA0C11627g Kluyveromyces lactis (yeast) 110908 Lottia gigantea (owl limpet) LmjF35.1130 Leishmania major (virus) ENSMMUP00000011289 Macaca mulatta (rhesus monkey) ENSMUSP00000035010 Mus musculus (house mouse) 238356 Nematostella vectensis (starlet anemone) XP_001601373.1 Nasonia vitripennis (wasp) ENSOANP00000003606 Ornithorynchus anatinus (platypus) ENSORLP00000005367 Oryzias latipes (japanese killifish) PHUM003715-PA Pediculus humanus (human body louse) PP09929 Pristionchus pacificus (nematode) ENSPPYP00000015716 Pongo pygmaeus (orangutan) ENSPTRP00000025378 Pan troglodytes (chimpanzee) ENSRNOP00000017243 Rattus norvegicus (norway rat) YGL022W Saccharomyces cerevisiae (budding yeast) Smp_158600 Schistosoma mansoni (trematode parasite) SPBC1271.02 Schizosaccharomyces pombe (fission yeast) XP_001181301.1 Strongylocentrotus purpuratus (purple sea urchin) 31147 Trichoplax adhaerens (metazoa) XP_972341.1 Tribolium castaneum (red flour beetle) Tc00.1047053505163.80 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009243 Tetraodon nigroviridis (green spotted pufferfish) 4160 Thalassiosira pseudonana (marine diatom) ENSTRUP00000033407 Takifugu rubripes (pufferfish Takifugu) YALI0B16434g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43005 modMine - Data generated by the modENCODE project. • FBgn0011336 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12469 NV15224 LH11924 ISCW022325 FBgn0228587 FBgn0215417 FBgn0210691 FBgn0189771 FBgn0172664 JGI_V11_307851 FBgn0243942 FBgn0159489 FBgn0146541 FBgn0127049 FBgn0104582 FBgn0094124 CPIJ008679 BGIBMGA004898 ACYPI004183 AGAP002396 AAEL015049 AAEL002804 PHUM459530 GLEAN_09183
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	anon-WO03054008.7   BcDNA:GM01838   BcDNA.GM01838 (Tsang, 1999.3.2) CG7748 (Arbeitman et al., 2004, Cammarato et al., 2011) l(3)j2D9 (Bartoszewski et al., 2004, Beaton, 2000.1.31, BDGP Project Members, 1994-1999, ) OstStt3 (Stuart et al., 2007, Tamura et al., 2010, Christensen et al., 2008.4.15, Christensen et al., 2008.4.15)
Name Synonym	Oligosaccharyl transferase 3 (Spradling et al., 1999, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0027069
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 4 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 4 ) Patent  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Tamura et al., 2010, J. Neurosci. 30(42): 14091--14101 Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. [FBrf0212135] Show all research papers ...