Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fzo using the Feature Mapper tool.
fzo protein is detected at the end of male meiosis and in early stage spermatids when mitochondrial fusion occurs.
fzo protein is associated with mitochondria in spermatids during a narrow developmental window. It is first detected in the last stages of meiosis II. In postmeiotic haploid spermatids, it is associated with aggregating mitochondria and is present at the highest levels on onion stage Nebenkerns. It is detected at lower levels on early elongation stage mitochondria.
GBrowse - Visual display of RNA-Seq signalsView Dmel\fzo in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: fzo anon-WO0125274.1 anon-WO0125274.25 anon-WO0125274.26
Source for merge of fzo anon-WO0125274.1 anon-WO0125274.25 anon-WO0125274.26 was sequence comparison ( date:051113 ).
Area matching Drosophila Fzo gene, Acc. No. U95821.
At the round spermatid stage all mitochondria in each haploid spermatid fuse into two large derivatives that interweave to form the nebenkern, in fzo mutants the mitochondria aggregate but fail to fuse. The defect is specific to fusion as each unfused mitochondrion elongates normally.