AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.47
2.6, 2.3 (northern blot)
658 (aa); 75 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ine using the Feature Mapper tool.
ine transcripts are uniformly distributed in cellular blastoderm embryos. During germ band extension, elevated levels are seen in the hindgut primordium. During germ band retraction, expression is observed in the midgut, Malpighian tubules, garland cells, anal plate, and foregut. ine is also expressed in the CNS in segmentally repeated cells flanking the ventral midline and in limited regions of the head. In late stage embryos, expression is also seen in tracheal pits and in pharyngeal muscle.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ine in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ine encodes a protein with a high degree of sequence similarity to members of the Na+/Cl--dependent neurotransmitter transporter family.
Mutations of ine cause increased transmitter release due to prolonged depolarization at the nerve terminal.