Gene Dmel\mas

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\mas for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

DGC clone LP06006 appears problematic: incomplete CDS

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

mas-RB

FBtr0073260

NM_079195

3657

1047

mas-RC

FBtr0332659

NM_001274479

3654

1046

Additional Transcript Data & Comments

Reported size (kB)

4.0 (northern blot)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

mas-PB

FBpp0073116

111.6

1047

7.77

NP_523919

AAF47850

mas-PC

FBpp0304905

111.4

1046

7.77

NP_001261408

AGB94103

Additional Polypeptide Data & Comments

Reported size (kDa)

1047 (aa); 77, 35 (kD observed)

Comments

The 35kD mas protein is the amino-terminal peptide processed from the mas proprotein.

The 77kD mas protein is a carboxy-terminal peptide processed from the FBgn0011653:mas@ proprotein.

A 112kD proprotein is processed into two peptides of 35kD (amino-terminal) and 77kD (carboxy-terminal).

External Data

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Peptidase S1, trypsin family, active site (IPR018114)

Peptidase S1 (IPR001254)

Peptidase S1A, chymotrypsin-type (IPR001314)

Trypsin-like cysteine/serine peptidase domain (IPR009003)

MEROPS - An information resource for peptidases and the proteins that inhibit them

•

S01.970

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 4 -- 6

anlage in statu nascendi

dorsal ectoderm anlage

Comment:anlage in statu nascendi

hindgut anlage in statu nascendi

organism | ubiquitous

posterior ectoderm anlage

Comment:anlage in statu nascendi

ventral ectoderm anlage

Comment:anlage in statu nascendi

embryonic stage 7 -- 8

hindgut anlage

posterior endoderm

embryonic stage 9 -- 10

posterior endoderm

embryonic stage 11 -- 12

atrium | precursor

Comment:reported as atrium primordium

dorsal epidermis primordium

hindgut proper primordium

midline primordium

ventral epidermis primordium

embryonic stage 11 -- 13

cell | subset of ventral midline

embryonic stage 12 -- 17

epidermis | anterior & segment boundary

embryonic stage 13 -- 16

atrium

embryonic dorsal epidermis

embryonic head epidermis

embryonic hindgut

embryonic tracheole

embryonic ventral epidermis

embryonic/larval dorsal trunk

embryonic/larval posterior spiracle

embryonic/larval visceral branch

ventral midline

embryonic stage 14 -- 17

embryonic/larval tracheal system

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- pupal stage

embryonic stage 11 -- 13

ventral midline | restricted

embryonic stage 12 -- 17

epidermis

embryonic stage 14 -- 17

tracheal system

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

tracheal system

embryonic stage 13

cell | subset of ventral midline

embryonic stage 14 -- 17

epidermis

embryonic/larval tracheal system

embryonic stage 16

epidermis | restricted

Comment:denticle belt region

denticle belt

tracheal lumen | vicinity of

Comment:surface of tracheal lumen

embryonic/larval tracheal system

Comment:surface of tracheal lumen

muscle attachment site

Additional Descriptive Data

The 77kD mas protein appears to be secreted.

The 35kD mas peptide is detected in epidermal cells starting in stage 14 and increases in intensity until stage 17. In older embryos, the strongest staining is associated with the denticles. Staining is also detected in the tracheal system from stage 14-17 in the cells lining the tracheal lumen.

Marker for

Subcellular Localization (GO Cellular Component)

CV term

References

plasma membrane

inferred from direct assay

(The modENCODE Consortium, 2010)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		95.225
Larval Midgut		9.2
Larval Hindgut		26.5
Larval Malpighian Tubules		1.9
Larval Fat Body		7.7
Larval Salivary Gland		4.3
Larval Trachea		32.075
Larval Carcass		27.275
Adult Head		3.4
Adult Eye		6.225
Adult Brain		1.1
Adult Thoracic-Abdominal Ganglion		1.3
Adult Crop		7.2
Adult Midgut		5.3
Adult Hindgut		2.5
Adult Malpighian Tubules		4.5
Adult Fat Body		2.6
Adult Salivary Gland		13.4
Adult Heart		1.85
Adult VirginFemale Spermatheca		2.9
Adult InseminatedFemale Spermatheca		2.4
Adult Ovary		1.7
Adult Testis		7.4
Adult Male Accessory Gland		8.7
Adult Carcass		11.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	3.4
NA	Eye	6.225
NA	Brain	1.1
95.225	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	1.3
NA	Crop	7.2
9.2	Midgut	5.3
no informative data	Hindgut	2.5
1.9	Malpighian Tubules	4.5
7.7	Fat Body	2.6
4.3	Salivary Gland	no informative data
NA	Heart	1.85
32.075	Trachea	NA
NA	VirginFemale Spermatheca	2.9
NA	InseminatedFemale Spermatheca	2.4
NA	Ovary	1.7
NA	Testis	7.4
NA	Male Accessory Gland	8.7
no informative data	Carcass	no informative data

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(61)
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		(28)
carcass, larvae L3 wandering		(36)
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(61)
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		(36)
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		61
central nervous system, larvae L3		18
central nervous system, pupae P8		8
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		7
digestive system, larvae L3 wandering		2
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		18
fat body, pupae P8		28
carcass, larvae L3 wandering		36
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		(37)
embryo 12-14hr		(104)
embryo 14-16hr		(66)
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		(58)
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		(79)
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		(37)
embryo 12-14hr		(104)
embryo 14-16hr		(66)
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		(58)
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		(79)
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		19
embryo 04-06hr		6
embryo 06-08hr		4
embryo 08-10hr		9
embryo 10-12hr		37
embryo 12-14hr		104
embryo 14-16hr		66
embryo 16-18hr		5
embryo 18-20hr		2
embryo 20-22hr		0
embryo 22-24hr		1
larva L1		2
larva L2		58
larva L3 12hr old		7
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		9
white prepupae new		22
white prepupae 12hr		3
white prepupae 24hr		21
pupae 2d postWPP		79
pupae 3d postWPP		19
pupae 4d postWPP		2
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		4
cold shock, 4-day adult		4
heat shock, 4-day adult		1
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		3
Cadmium 50 mM 48 hrs, 4-day adult		3
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		8
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		1
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

mE2_34_mRNA_expression_cluster_25

External Data & Images

Show all FlyExpress processed images for mas

BDGP expression data

•

RE29416

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0011653

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG15002-RB

FlyExpress - Embryonic expression images (BDGP data)

•

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal | embryonic stage | recessive

lethal | pupal stage, with Scer\GAL4^pnr-MD237

mas^GD6002

lethal | recessive

Other Phenotypes

Allele

smell perception defective

mas^P

taste perception defective

Phenotype manifest in

Allele

aCC neuron

commissure

lateral oblique muscle 1

lateral transverse muscle

longitudinal connective

pCC neuron

peripheral nervous system

ventral acute muscle

ventral longitudinal muscle

Classical Alleles ( 8 )

For All Classical Alleles Show

Allele of mas	Class	Mutagen	Stocks	Known lesion
mas^xs76	amorphic allele - genetic evidence, loss of function allele	Delta2-3	1	Yes
mas^c01899		piggyBac transposase	1	--
mas^MB11963			1	--
mas^MI01486			1	--
mas^MI06252			1	--
mas^P	loss of function allele	P-element activity	1	Yes
mas^x124	loss of function allele, amorphic allele - genetic evidence	Delta2-3	0	Yes
mas¹⁵⁴	hypomorphic allele - genetic evidence	Delta2-3	0	Yes

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of mas	Mutagen	Stocks	Known lesion
mas^GD6002	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mas^KK103120	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mas^hs.PMO	in vitro construct - minigene in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3L)BSC735

(Christensen et al., 2009.2.28)

Df(3L)Exel6100

(Ryder, 2004.4.26)

Df(3L)nab¹⁶⁰⁰

(Clements et al., 2003)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD6002}

P{KK103120}

heat-shock construct

P{hs-mas}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

insertion of enhancer trap binary system

Mi{ET1}mas^MB11963

Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process ( 0 terms)

Cellular Component

CV term

References

plasma membrane

inferred from direct assay

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function

CV term

serine-type endopeptidase activity

References

NOT
peptidase activity

traceable author statement

(Theopold et al., 2002)

NOT
serine-type endopeptidase activity

non-traceable author statement

(Ross et al., 2003)

inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114

(FlyBase Curators et al., 2004-)

Biological Process

CV term

(FlyBase Curators et al., 2004-)

References

proteolysis

inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

mas allele

Gene

References

mas^xs76

nab

(Clements et al., 2003)

External Data

Rnor\RGD1563955_predicted

BioGRID - A database of protein and genetic interactions

•

63977

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0011653

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38499

Orthologs

OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6WDDX7

Dipteran inclusive ortholog search

EOG6C2HJP

Insect inclusive ortholog search

EOG605QW7

Arthropod inclusive ortholog search

EOG6CRJF5

Metazoa inclusive ortholog search

EOG63FVPZ

Orthologs in Drosophila Species (EOG6WDDX7)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA13420

Drosophila persimilis

Dper\GL12735

Drosophila willistoni

Dwil\GK10062

Drosophila virilis

Dvir\GJ12575

Drosophila mojavensis

Dmoj\GI16827

Drosophila grimshawi

Dgri\GH15552

Orthologs in non-Drosophila Dipterans (EOG6C2HJP)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL002126

Anopheles gambiae

Malaria mosquito

Agam\CLIPA15

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004302

Orthologs in non-Dipteran Insects (EOG605QW7)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\Ame.2888

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG012290

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH23481

Atta cephalotes

Leafcutter ant

Acep\ACEP17271

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO23074

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL23117

Linepithema humile

Argentine ant

Lhum\LH16975

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB14483

Solenopsis invicta

Red fire ant

Sinv\SINV23441

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI005371

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI085301

Bombyx mori

Silkmoth

Bmor\BGIBMGA008665

Pediculus humanus

Human body louse

Phum\PHUM227210

Tribolium castaneum

Red flour beetle

Tcas\H51

Orthologs in non-Insect Arthropods (EOG6CRJF5)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_230054

Daphnia pulex

Water flea

Dpux\JGI_V11_314689

Daphnia pulex

Water flea

Dpux\JGI_V11_194367

Ixodes scapularis

Deer tick

Isca\ISCW005538

Orthologs in non-Arthropod Metazoa (EOG63FVPZ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Danio rerio

Zebrafish

Drer\si:dkey-76d14.1

Gallus gallus

Domestic chicken

Ggal\LOC424939

Rattus norvegicus

Norway rat

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA13420

Drosophila persimilis

Dper\GL12735

Drosophila willistoni

Dwil\GK10062

Drosophila virilis

Dvir\GJ12575

Drosophila mojavensis

Dmoj\GI16827

Drosophila grimshawi

Dgri\GH15552

Stocks & Reagents

Stocks Listed in FlyBase ( 8 )

Bloomington

657

mas^xs76 h^*/TM3, Sb¹ P{35UZ}2

29267

w¹¹¹⁸; Mi{ET1}mas^MB11963/TM6C, Sb¹

34439

y¹ w^*; Mi{MIC}mas^MI01486/TM3, Sb¹ Ser¹

42141

y¹ w^*; Mi{MIC}mas^MI06252/TM3, Sb¹ Ser¹

5152

w¹¹¹⁸; P{wF}mas^P ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹

v103955

v32263

w¹¹¹⁸; P{GD6002}v32263/TM3

Genomic Clones ( 1 )

BACR48M07

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 26 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

(Murugasu-Oei et al., 1995, Murugasu-Oei et al., 1995)

DRSC - Results from RNAi screens.

•

FBgn0011653

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

38499

Antibody Information

polyclonal

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

mas is expressed in relevant cell types during embryonic, larval and pupal life. Total loss of mas function in the embryo results in defects in the axonal connectivities of the motor as well as sensory axons. Defects in information processing by the neuronal pathways is the underlying cause for the aberrant taste behaviour exhibited by larvae and adults mutant for mas.

(Murugasu-Oei et al., 1996)

Total loss of mas function causes defective muscle attachment, this suggests mas normally acts to stabilise cell-matrix interaction and represents a novel functional and limiting component in the adhesion process.