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General Information
Symbol
Dmel\Moe
Species
D. melanogaster
Name
Moesin
Annotation Symbol
CG10701
Feature Type
FlyBase ID
FBgn0011661
Gene Model Status
Stock Availability
Gene Snapshot
Moesin (Moe) encodes an Ezrin, Radixin, Moesin (ERM) protein involved in cortical cytoskeleton stability. It regulates the products of crb and Rho1. The product of Moe contributes to apical-basal polarity, mitotic spindle organisation and epithelial integrity. [Date last reviewed: 2019-03-14]
Also Known As
Dmoesin, Dmoe, l(1)G0067, l(1)G0415, l(1)G0404
Key Links
Genomic Location
Cytogenetic map
Sequence location
X:8,873,012..8,898,332 [-]
Recombination map
1-25
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Summaries
Protein Function (UniProtKB)
Involved in connections of major cytoskeletal structures to the plasma membrane (PubMed:8666669). Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr (PubMed:23544124). In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles (PubMed:28554770).
(UniProt, P46150)
Summary (Interactive Fly)
the sole Drosophila Ezrin, Radixin, Moesin (ERM) protein - involved in cortical cytoskeleton stability - actin-binding protein - functions to promote cortical actin assembly, apical-basal polarity and mitotic spindle organisation - Crumbs displays complex dynamics during follicular morphogenesis and is regulated competitively by Moesin and aPKC
Gene Model and Products
Number of Transcripts
13
Number of Unique Polypeptides
7

Please see the GBrowse view of Dmel\Moe or the JBrowse view of Dmel\Moe for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.45
Gene model reviewed during 5.55
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0071271
2353
640
FBtr0071270
2462
649
FBtr0071272
2027
512
FBtr0071269
3003
575
FBtr0071273
2283
575
FBtr0071274
2919
575
FBtr0071275
2295
575
FBtr0071276
2236
575
FBtr0071277
2282
575
FBtr0071278
2401
578
FBtr0308193
3064
646
FBtr0308194
2528
578
FBtr0331601
2995
584
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0071214
75.3
640
5.48
FBpp0071213
76.2
649
6.02
FBpp0071215
60.6
512
5.53
FBpp0071212
67.9
575
5.78
FBpp0089231
67.9
575
5.78
FBpp0089232
67.9
575
5.78
FBpp0089233
67.9
575
5.78
FBpp0089234
67.9
575
5.78
FBpp0089235
67.9
575
5.78
FBpp0089236
68.1
578
5.78
FBpp0300513
75.9
646
6.02
FBpp0300514
68.1
578
5.78
FBpp0303991
68.9
584
5.78
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

575 aa isoforms: Moe-PD, Moe-PE, Moe-PF, Moe-PG, Moe-PH, Moe-PI
578 aa isoforms: Moe-PJ, Moe-PL
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)
Interacts with wgn (PubMed:23544124). Interacts with Mer and arm at the adherens junction (PubMed:8666669). Interacts with cytoskeletal actin at apical buds of microvilli in the precellularised embryo (PubMed:8666669). Interacts with PCID2 (possibly via FERM domain) (PubMed:28554770).
(UniProt, P46150)
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Moe using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (49 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
inferred from direct assay
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from physical interaction with FLYBASE:Mer; FB:FBgn0086384
inferred from physical interaction with FLYBASE:conu; FB:FBgn0039994
inferred from physical interaction with UniProtKB:Q9VTL1
(assigned by UniProt )
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
non-traceable author statement
Biological Process (29 terms)
Terms Based on Experimental Evidence (20 terms)
CV Term
Evidence
References
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from direct assay
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
(assigned by UniProt )
inferred from mutant phenotype
inferred from mutant phenotype
(assigned by UniProt )
Terms Based on Predictions or Assertions (9 terms)
CV Term
Evidence
References
Cellular Component (16 terms)
Terms Based on Experimental Evidence (15 terms)
CV Term
Evidence
References
colocalizes_with actin cytoskeleton
inferred from direct assay
colocalizes_with actin filament
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
colocalizes_with cytoplasm
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
NOT fusome
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
colocalizes_with nucleus
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
(assigned by UniProt )
colocalizes_with spindle
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
non-traceable author statement
non-traceable author statement
traceable author statement
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
organism

Comment: maternally deposited

Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Moe protein localizes to the base of the rhabdomere, and is seen in this location from about 50% through pupal development.
Use of a Moe-GFPfusion construct was used as a marker of actin bundles in 32-56 hour developing pupal bristles in the thorax.
Marker for
 
Subcellular Localization
CV Term
Evidence
References
colocalizes_with actin cytoskeleton
inferred from direct assay
colocalizes_with actin filament
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
colocalizes_with cytoplasm
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
NOT fusome
inferred from direct assay
inferred from direct assay
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
colocalizes_with nucleus
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
inferred from direct assay
(assigned by UniProt )
colocalizes_with spindle
inferred from direct assay
inferred from direct assay
(assigned by UniProt )
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Moe in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 63 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 52 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Moe
Transgenic constructs containing regulatory region of Moe
Deletions and Duplications ( 4 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
nurse cell & actin filament
nurse cell & actin filament, with Scer\GAL4Moe-PG26
nurse cell & actin filament, with Scer\GAL4VP16.nos.UTR
oocyte & actin filament
oocyte & actin filament | ectopic, with Scer\GAL4VP16.nos.UTR
oocyte & cytoskeleton (with MoeEP1652)
oocyte & cytoskeleton (with MoeEP1652), with Scer\GAL4- :
oocyte & cytoskeleton (with MoeG0415)
oocyte & cytoskeleton (with MoeG0415), with Scer\GAL4- :
rhabdomere & actin filament | somatic clone
rhabdomere & cytoskeleton | apical, with Scer\GAL4hs.PB
rhabdomere & microvillus, with Scer\GAL4hs.PB
rhabdomere & plasma membrane | apical, with Scer\GAL4hs.PB
rhabdomere & plasma membrane | apical | somatic clone
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
14 of 15
Yes
Yes
13 of 15
No
Yes
11 of 15
No
Yes
 
3 of 15
No
No
 
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
14 of 15
Yes
Yes
13 of 15
No
Yes
13 of 15
No
Yes
2 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (7)
11 of 13
Yes
Yes
9 of 13
No
Yes
7 of 13
No
Yes
3 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (7)
8 of 12
Yes
Yes
7 of 12
No
Yes
4 of 12
No
Yes
2 of 12
No
No
1 of 12
No
Yes
1 of 12
No
Yes
1 of 12
No
Yes
Danio rerio (Zebrafish) (13)
13 of 15
Yes
Yes
11 of 15
No
Yes
10 of 15
No
Yes
7 of 15
No
Yes
3 of 15
No
No
3 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (3)
14 of 15
Yes
Yes
3 of 15
No
No
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
1 of 12
Yes
Yes
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091904HL )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503BH )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0338 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Megachile rotundata
Alfalfa leafcutting bee
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0303 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Ixodes scapularis
Black-legged tick
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G06UO )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Ciona intestinalis
Vase tunicate
Ciona intestinalis
Vase tunicate
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (2)
5 of 10
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser

    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Subunit Structure (UniProtKB)
    Interacts with wgn (PubMed:23544124). Interacts with Mer and arm at the adherens junction (PubMed:8666669). Interacts with cytoskeletal actin at apical buds of microvilli in the precellularised embryo (PubMed:8666669). Interacts with PCID2 (possibly via FERM domain) (PubMed:28554770).
    (UniProt, P46150 )
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Gene Group - Pathway Membership (FlyBase)
    External Data
    Linkouts
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map
    1-25
    Cytogenetic map
    Sequence location
    X:8,873,012..8,898,332 [-]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    8B4-8B6
    (determined by in situ hybridisation); Limits computationally determined from genome sequence between P{EP}CG1632EP1583 and P{EP}MoeEP1652
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    8B4-8B4
    (determined by in situ hybridisation)
    8B1-8B4
    (determined by in situ hybridisation) 8B3--7 (determined by in situ hybridisation)
    8B1-8B4
    (determined by in situ hybridisation)
    8E3-8E4
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Location
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (54)
    Genomic Clones (13)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (412)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    Antibody Information
    Laboratory Generated Antibodies
     
    Commercially Available Antibodies
     
    Other Information
    Relationship to Other Genes
    Source for database identify of
    Source for database merge of
    Source for merge of: Moe l(1)G0323
    Source for merge of: Moe l(1)G0415
    Source for merge of: Moe anon-WO03040301.155 anon-WO03040301.157 anon-WO03040301.159 anon-WO03040301.161
    Additional comments
    "l(1)G0187" may affect "Moe".
    Source for merge of Moe anon-WO03040301.155 anon-WO03040301.157 anon-WO03040301.159 anon-WO03040301.161 was sequence comparison ( date:051113 ).
    Other Comments
    The effect of slik on Mer is not mediated through its effects on Moe activation.
    Mutations that impair phosphorylation of Moe abolish the movement of Moe upon illumination and result in light-activated degeneration of the photoreceptor cells.
    dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
    dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.
    Moe is required to maintain apical-basal polarity, epithelial integrity and correct actin distribution in imaginal disc cells.
    Mutant phenotypes include lethality, female sterility and imperfect eye and wing development, in addition to a maternal effect loss of germ cells in embryos.
    Alteration of the actin cytoskeleton in oocytes resulting from Moe mutations impairs the localization of maternal determinants, thus disrupting antero-posterior polarity. Moe mutations also lead to defects in the actin cytoskeleton of nurse cells and consequently produce severe defects in nurse-cell shape.
    Moe is required during oogenesis for anchoring microfilaments to the oocyte cortex.
    Transcript induced by MMS treatment of S1CII cells.
    Mer and Moe are frequently coexpressed in developing tissues, but their subcellular localisations are distinct. Moe shows continuous plasma membrane association and Mer is localised in punctate structures that are associated with both the plasma membrane and the cytoplasm.
    The Moe gene product is not a component of fusome.
    A yeast phenotypic screen efficiently identifies conserved genes from more complex organisms and sheds light on their potential in vivo functions. Induced expression of Moe proteins causes aberrant cell shapes reflecting defects in cytokinesis and/or cell shape maintenance.
    Origin and Etymology
    Discoverer
    Etymology
    Identification
    External Crossreferences and Linkouts ( 107 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
    Other crossreferences
    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
    Flygut - An atlas of the Drosophila adult midgut
    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
    KEGG Genes - Molecular building blocks of life in the genomic space.
    modMine - A data warehouse for the modENCODE project
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DPiM - Drosophila Protein interaction map
    DroID - A comprehensive database of gene and protein interactions.
    DRSC - Results frm RNAi screens
    FLIGHT - Cell culture data for RNAi and other high-throughput technologies
    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
    FlyMine - An integrated database for Drosophila genomics
    Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
    InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
    MIST (genetic) - An integrated Molecular Interaction Database
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
    Synonyms and Secondary IDs (30)
    Reported As
    Symbol Synonym
    Emr1
    Moe
    (Fouchécourt et al., 2019, Xu et al., 2019, Gene Disruption Project members, 2018-, Lee et al., 2018, Molinar-Inglis et al., 2018, Salis et al., 2017, Transgenic RNAi Project members, 2017-, Clandinin and Owens, 2016-, David-Morrison et al., 2016, Duque and Gorfinkiel, 2016, Flores-Benitez and Knust, 2016, Silva et al., 2016, Wang et al., 2016, Yadav et al., 2016, Miao and Hayashi, 2015, Panneton et al., 2015, Sabino et al., 2015, Sherrard and Fehon, 2015, Ashwal-Fluss et al., 2014, Butí et al., 2014, Hsieh et al., 2014, Luck et al., 2014, Pézeron et al., 2014, Schottenfeld-Roames et al., 2014, Ukken et al., 2014, Fuse et al., 2013, Klose et al., 2013, Kwon et al., 2013, Nakajima et al., 2013, Neisch et al., 2013, Salzmann et al., 2013, Sen et al., 2013, Song et al., 2013, Terriente-Felix et al., 2013, Förster and Luschnig, 2012, Japanese National Institute of Genetics, 2012.5.21, Friedman et al., 2011, Letizia et al., 2011, Mukherjee et al., 2011, Xu et al., 2011, Blanchard et al., 2010, David et al., 2010, Forster et al., 2010, Foussard et al., 2010, Georgiou and Baum, 2010, Gervais and Casanova, 2010, Hughes et al., 2010, Ling et al., 2010, Monier et al., 2010, Neisch et al., 2010, Neubueser and Hipfner, 2010, Popodi et al., 2010-, Robinson et al., 2010, Roch et al., 2010, Simone and DiNardo, 2010, Tajiri et al., 2010, Dworkin et al., 2009, Genevet et al., 2009, Grusche et al., 2009, Moran and Kyriacou, 2009, Solon et al., 2009, Vilmos et al., 2009, Wolfstetter et al., 2009, Zanet et al., 2009, Carreno et al., 2008, Cavey et al., 2008, Chang et al., 2008, Cheshire et al., 2008, Gervais et al., 2008, Homem and Peifer, 2008, Kunda et al., 2008, Rauzi et al., 2008, Toyama et al., 2008, Bakal et al., 2007, Fox and Peifer, 2007, Garcia et al., 2007, Kerman et al., 2007, Li et al., 2007, Macdonald and Long, 2007, Nishimura et al., 2007, Polesello and Tapon, 2007, Robida et al., 2007, Stuart et al., 2007, Taniguchi et al., 2007, Blankenship et al., 2006, Hughes and Fehon, 2006, Jankovics and Brunner, 2006, Molnar et al., 2006, Ramos et al., 2006, Cabernard and Affolter, 2005)
    anon-WO03040301.155
    anon-WO03040301.157
    anon-WO03040301.159
    anon-WO03040301.161
    moesin/ezrin/radixin homolog mRNA
    Name Synonyms
    Ezrin-Radixin-Moesin
    Ezrin-moesin-radixin-1
    Moesin
    (Saito et al., 2018, Schmidt and Grosshans, 2018, Freymuth and Fitzsimons, 2017, Battistini and Tamagnone, 2016, Duque and Gorfinkiel, 2016, Schimizzi et al., 2016, Wang et al., 2016, Chakrabarti et al., 2015, Sabino et al., 2015, Sherrard and Fehon, 2015, Bausek and Zeidler, 2014, Carvalho et al., 2014, Hsieh et al., 2014, Jayanandanan et al., 2014, Schottenfeld-Roames et al., 2014, Tan et al., 2014, Ukken et al., 2014, Antunes et al., 2013, Guillot and Lecuit, 2013, Manhire-Heath et al., 2013, Solinet et al., 2013, Förster and Luschnig, 2012, Kunda et al., 2012, Tepass, 2012, Yano et al., 2012, Zanet et al., 2012, Zoller and Schulz, 2012, Cohen et al., 2011, Galy et al., 2011, Letizia et al., 2011, Mukherjee et al., 2011, Olguín et al., 2011, Rotkopf et al., 2011, Tucker et al., 2011, Blanchard et al., 2010, David et al., 2010, Foussard et al., 2010, Hughes et al., 2010, Khuong et al., 2010, Ling et al., 2010, Neisch et al., 2010, Neubueser and Hipfner, 2010, Robinson et al., 2010, Roch et al., 2010, Siekhaus et al., 2010, Tajiri et al., 2010, Bradu et al., 2009, Genevet et al., 2009, Grusche et al., 2009, Hijazi et al., 2009, Lebo et al., 2009, Liu et al., 2009, Martin et al., 2009, Massarwa et al., 2009, Solon et al., 2009, Webb et al., 2009, Cao et al., 2008, Carreno et al., 2008, Chang et al., 2008, Cheshire et al., 2008, Gervais et al., 2008, Homem and Peifer, 2008, Hoopfer et al., 2008, Kerman et al., 2008, Kunda et al., 2008, Millard and Martin, 2008, Bakal et al., 2007, Besse et al., 2007, Gregory et al., 2007, Kerman et al., 2007, Mitonaka et al., 2007, Neisch et al., 2007, Polesello and Tapon, 2007, Prasad and Montell, 2007, Riggs et al., 2007, Baum, 2006, Blankenship et al., 2006, Fehon, 2006, Hughes and Fehon, 2006, Medina et al., 2006, Pilot et al., 2006, Price et al., 2006, Sambandan et al., 2006, Schneider et al., 2006, Silva et al., 2006, Walters et al., 2006, Weis and Nelson, 2006, Fox et al., 2005, Schwabe et al., 2005, de Heredia and Jansen, 2004, Rogers et al., 2003)
    moesin
    (Franz et al., 2018, Hayes and Solon, 2017, Hunter et al., 2015, Rodrigues et al., 2015, Siegenthaler et al., 2015, Fernandez-Gonzalez and Zallen, 2013, Manning et al., 2013, Peters et al., 2013, Song et al., 2013, Sano et al., 2012, Wheeler et al., 2012, Abreu-Blanco et al., 2011, Boggiano et al., 2011, Cheng et al., 2011, Fernandez-Gonzalez and Zallen, 2011, Geiger et al., 2011, Hatan et al., 2011, Kanesaki et al., 2011, Parkhurst, 2011.4.14, Cohen et al., 2010, Fabian et al., 2010, Fishilevich et al., 2010, Gervais and Casanova, 2010, He et al., 2010, Khuong et al., 2010, Okumura et al., 2010, Roch et al., 2010, Sekyrova et al., 2010, Kaido et al., 2009, Leiss et al., 2009, Ma et al., 2009, Sawyer et al., 2009, Sheng et al., 2009, Vilmos et al., 2009, Vlisidou et al., 2009, Wang et al., 2009, Widmann and Dahmann, 2009, Carreno et al., 2008, Cavey et al., 2008, Kakihara et al., 2008, Royou et al., 2008, Seabrooke and Stewart, 2008, Shindo et al., 2008, Stramer et al., 2008, Weil et al., 2008, Fox and Peifer, 2007, Inoue and Hayashi, 2007, Kondo et al., 2007, Maddox et al., 2007, Seabrooke and Stewart, 2007, Tsarouhas et al., 2007, Wada et al., 2007, Franke et al., 2006, Hozumi et al., 2006, Laplante and Nilson, 2006, Oshima, 2006, Oshima et al., 2006, Peyre et al., 2006, Pilot et al., 2006, Golovnina et al., 2005, Sano et al., 2005, Stramer et al., 2005, Harris and Peifer, 2004, Somogyi and Rorth, 2004, Fei et al., 2002, Dorman et al., 2000, Dove, 2000, Turunen et al., 1998)
    Secondary FlyBase IDs
    • FBgn0013950
    • FBgn0014345
    • FBgn0026689
    • FBgn0027218
    • FBgn0028282
    • FBgn0028289
    • FBgn0066841
    • FBgn0066842
    • FBgn0066843
    • FBgn0066844
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    References (460)