Sed5, l(2)35Ff, Syntaxin, BG:DS02740.12 , dSyx5
a Golgi-localized SNARE protein - required for ER-Golgi traffic and Golgi reassembly following cell division - required for steps leading to formation of mature sperm
Please see the JBrowse view of Dmel\Syx5 for information on other features
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Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.48
1.0 (northern blot)
310 (aa)
Homodimer.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Syx5 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Syx5 in GBrowse 22-52
2-52
2-49.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Sed5 CG4214
Source for identity of: Syx5 Sed5
Source for merge of: Sed5 l(2)35Ff anon-35Fd anon-35Fb
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene was tested in an RNAi screen to identify genes that regulate Ca2+ release.
Identified in an RNAi screen for host factors that alter infection of SL2 cells by L.monocytogenes.
dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Syx5 is required for the proper function of the Golgi apparatus, and as a consequence required for cytokinesis and spermatid differentiation.
Transcript identified during molecular analysis of the fzy genomic region.
Identified as a transcript in the cni region.
1 allele is discussed but is not named.