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Gene Dmel\Gem3

General Information
Symbol	Dmel\Gem3	Species	D. melanogaster
Name	Gemin3	Annotation symbol	CG6539
Feature type	protein_coding_gene	FlyBase ID	FBgn0011802
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	DHH1, l(3)rL562
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	67E3-67E3	Sequence location	3L:10,452,181..10,456,201 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Gemin3 is referred to in FlyBase by the symbol Dmel\Gem3 (CG6539, FBgn0011802). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent RNA helicase activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process: ribonucleoprotein complex assembly; neuromuscular junction development. 9 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; puparium; embryonic/larval neuromuscular junction; anterior pupal spiracle; indirect flight muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, DEAD-box type, Q motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1629281_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Gem3. Gene sequence location is 3L:10452181..10456201.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 67E3-67E3   Limits computationally determined from genome sequence between P{lacW}l(3)L0539L0539&P{PZ}Dhh1rL562 and P{PZ}simj01814
Experimentally Determined Cytological Location
Cytogenetic map Notes References 67E1-67E4   (determined by in situ hybridisation)   (Spradling et al., 1999) 67E1-67E4     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Gem3 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Gem3-RA FBtr0076292  NM_079295   3423   1028 Gem3-RB FBtr0334100  NM_001274749   3963   1028
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Gem3-PA   FBpp0076021   116.5   1028   7.16     NP_524019   AAF50157 Gem3-PB   FBpp0306223   116.5   1028   7.16     NP_001261678   AGB94372
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014) P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246642   AA264452   AE014296 AAF50157   AF160911 AAD46851   AE014296 AGB94372   AI531391   AI541956   AQ026370   BG637908   BG639554   BI171515   BI172549   BI361927   CO284152   CO295213   EC247540   GH755647   GH781535   GH787180   GH797650   GH804483   GH812227   GH839840   GH845155   GH845996   GH853594   GH857361   GH859522   GH862851   GH869595   GH875718   GH876048   GH878123   GH886166   GH889255   GH891778   GH900113   GH922044   GH928202   GH931442   GH933820   GH934128   GH936452
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3C4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Cajal body inferred from direct assay (Shpargel et al., 2009) cytoplasm inferred from direct assay (Shpargel et al., 2009) cytoplasmic U snRNP body inferred from direct assay (Cauchi et al., 2010)
Expression Deduced from Reporters
Reporter: P{PZ}Gem3rL562 Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage   eye disc   (Meister and Braun, 1995.10)
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    94.4 Larval Midgut    17.1 Larval Hindgut    26.6 Larval Malpighian Tubules    27.6 Larval Fat Body    29 Larval Salivary Gland    36.4 Larval Trachea    44.325 Larval Carcass    32.35 Adult Head    25.5 Adult Eye    18.125 Adult Brain    38 Adult Thoracic-Abdominal Ganglion    35 Adult Crop    29.9 Adult Midgut    20.9 Adult Hindgut    23.6 Adult Malpighian Tubules    33.4 Adult Fat Body    16.2 Adult Salivary Gland    25.2 Adult Heart    16.475 Adult VirginFemale Spermatheca    26.2 Adult InseminatedFemale Spermatheca    31 Adult Ovary    314 Adult Testis    170.5 Adult Male Accessory Gland    24.5 Adult Carcass    21.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    25.5   NA  Eye    18.125   NA  Brain    38   94.4  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    35   NA  Crop    29.9   17.1  Midgut    20.9   26.6  Hindgut    23.6   27.6  Malpighian Tubules    33.4   29  Fat Body    16.2   36.4  Salivary Gland    no informative data   NA  Heart    16.475   44.325  Trachea    NA   NA  VirginFemale Spermatheca    26.2   NA  InseminatedFemale Spermatheca    31   NA  Ovary    314   NA  Testis    170.5   NA  Male Accessory Gland    24.5   32.35  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female  (31) ovary, mated 4-day female  26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female  31 ovary, mated 4-day female  26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    5 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    2 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    2 carcass, larvae L3 wandering    5 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    31 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (28) embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    18 embryo 04-06hr    15 embryo 06-08hr    11 embryo 08-10hr    12 embryo 10-12hr    7 embryo 12-14hr    8 embryo 14-16hr    5 embryo 16-18hr    5 embryo 18-20hr    2 embryo 20-22hr    6 embryo 22-24hr    6 larva L1    2 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    8 white prepupae new    6 white prepupae 12hr    7 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    7 pupae 4d postWPP    4 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    6 adult female 05day    19 adult female 30day    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    7 embryonic 1182-4H    6 embryonic GM2    3 embryonic Kc167    6 embryonic S1    4 embryonic S3    8 leg disc CME L1    7 wing disc CME-W2    12 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    5 wing disc ML-DmD32    4 haltere disc ML-DmD17-c3    11 eye-antennal disc ML-DmD11    4 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    5 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    8 ovary fGS/OSS    12 ovary OSC    12 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    4 cold shock, 4-day adult    4 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    18 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    13 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011802 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6539-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4Act5C.PU Gem3GD17221 Gem3ΔN.Scer\UAS lethal, with Scer\GAL4c179 Gem3GD17221 Gem3ΔN.Scer\UAS lethal, with Scer\GAL4how-24B Gem3GD17221 Gem3ΔN.Scer\UAS lethal (with Df(3L)ED4457) Gem3e03688 Gem3rL562 lethal (with Gem3e03688) Gem3rL562 lethal (with Gem3rL562) Gem3e03688 lethal | heat sensitive, with Scer\GAL4G7 Gem3ΔN.Scer\UAS lethal | larval stage (with Gem3e03688) Gem3rL562 lethal | larval stage (with Gem3rL562) Gem3e03688 lethal | larval stage | recessive Gem3e03688 Gem3rL562 lethal | partially | heat sensitive, with Scer\GAL4C57 Gem3ΔN.Scer\UAS lethal | partially | heat sensitive, with Scer\GAL4Mef2.PR Gem3ΔN.Scer\UAS lethal | recessive Gem3e03688 Gem3rL562 partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Gem3GD1417 viable Gem3B-rev viable, with Scer\GAL4D42 Gem3GD17221 Gem3ΔN.Scer\UAS viable, with Scer\GAL4elav-C155 Gem3GD17221 Gem3ΔN.Scer\UAS viable, with Scer\GAL4nrv2.PS Gem3GD17221 Gem3ΔN.Scer\UAS viable, with Scer\GAL4pnr-MD237 Gem3GD17221 viable, with Scer\GAL4Rapgap1-OK6 Gem3GD17221 Gem3ΔN.Scer\UAS Other Phenotypes Allele developmental rate defective | larval stage Gem3rL562 flight defective, with Scer\GAL4Mef2.PR Gem3ΔN.Scer\UAS locomotor behavior defective | larval stage Gem3e03688 Gem3rL562 locomotor behavior defective | third instar larval stage (with Gem3e03688) Gem3rL562 locomotor behavior defective | third instar larval stage (with Gem3rL562) Gem3e03688 neuroanatomy defective | larval stage, with Scer\GAL41032.hx Gem3Scer\UAS.T:Avic\GFP-CFP neuroanatomy defective | larval stage (with Gem3e03688) Gem3rL562 neuroanatomy defective | larval stage (with Gem3rL562) Gem3e03688 small body | larval stage Gem3e03688 Gem3rL562 visible, with Scer\GAL4pnr-MD237 Gem3GD17221 Phenotype manifest in Allele anterior pupal spiracle (with Gem3e03688) Gem3rL562 anterior pupal spiracle (with Gem3rL562) Gem3e03688 embryonic/larval neuromuscular junction, with Scer\GAL41032.hx Gem3Scer\UAS.T:Avic\GFP-CFP embryonic/larval neuromuscular junction (with Gem3e03688) Gem3rL562 embryonic/larval neuromuscular junction (with Gem3rL562) Gem3e03688 head | pupal stage, with Scer\GAL4how-24B Gem3ΔN.Scer\UAS indirect flight muscle, with Scer\GAL4Mef2.PR Gem3ΔN.Scer\UAS leg | pupal stage, with Scer\GAL4how-24B Gem3ΔN.Scer\UAS puparium (with Gem3e03688) Gem3rL562 puparium (with Gem3rL562) Gem3e03688 trichogen cell, with Scer\GAL4pnr-MD237 Gem3GD17221 wing | pupal stage, with Scer\GAL4how-24B Gem3ΔN.Scer\UAS
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Gem3 Class Mutagen Stocks Known lesion Gem3e03688 amorphic allele - genetic evidence 1 Yes Gem3rL562 amorphic allele - genetic evidence P-element activity 1 Yes Gem3B-rev P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Gem3 Class Mutagen Stocks Known lesion Gem3GD17221 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Gem3GD1417 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gem3HMS00287 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gem3Scer\UAS.T:Avic\GFP-CFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Gem3Scer\UAS.T:Zzzz\FLAG in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes Gem3ΔN.Scer\UAS in vitro construct - regulatory fusion in vitro construct - deletion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(3L)AC1 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(3L)lxd6 (Spradling et al., 1999)
Disrupted in	Df(3L)ED4457 (Shpargel et al., 2009, Cauchi et al., 2008)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.HMS00287} NA P{UAS-Gem3.CFP} NA P{UAS-Gem3.FLAG} NA P{UAS-Gem3.ΔN} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}Gem3rL562 No miscellaneous insertions PBac{?RB}Gem3e03688 NA
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neuromuscular junction development inferred from mutant phenotype (Cauchi et al., 2008) ribonucleoprotein complex assembly inferred from mutant phenotype (Shpargel et al., 2009)
Cellular Component
CV term Evidence References
Cajal body inferred from direct assay (Shpargel et al., 2009) cytoplasm inferred from direct assay (Shpargel et al., 2009) cytoplasmic U snRNP body inferred from direct assay (Cauchi et al., 2010)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent RNA helicase activity inferred from sequence or structural similarity with UniProtKB:P54824 (FlyBase, 1992-) nucleic acid binding inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) RNA helicase activity inferred from sequence or structural similarity (Spradling et al., 1999)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Gem3 - CG2941 experimental knowledge based (Guruharsha et al., 2011) Gem3 - Gem2 experimental knowledge based (Guruharsha et al., 2011) Gem3 - Mtpα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Gem3 - Smn anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based, anti tag western blot, western blot, pull down (Mintseris et al., 2009.11.23, Guruharsha et al., 2011, Shpargel et al., 2009) Gem3 - imd anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Gem3 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64576 DroID - A comprehensive database of gene and protein interactions. • FBgn0011802 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39195
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6CJW2Q Dipteran inclusive ortholog search EOG6NCMN2 Insect inclusive ortholog search EOG647DPF Arthropod inclusive ortholog search EOG6QFTVF Metazoa inclusive ortholog search EOG6F28W9
Orthologs in Drosophila Species (EOG6CJW2Q)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Gem3     Drosophila simulans   Dsim\GD12861 Y   Drosophila sechellia   Dsec\GM24810 Y   Drosophila erecta   Dere\GG13972 Y   Drosophila yakuba   Dyak\GE20271 Y   Drosophila ananassae   Dana\GF23832 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23460 Y   Drosophila persimilis   Dper\GL15598 Y   Drosophila willistoni   Dwil\GK24052 Y   Drosophila virilis   Dvir\GJ11703 Y   Drosophila mojavensis   Dmoj\GI13838 Y   Drosophila grimshawi   Dgri\GH16548 Y
Orthologs in non-Drosophila Dipterans (EOG6NCMN2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004911   Anopheles gambiae Malaria mosquito  Agam\AGAP005391   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ014211   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013247
Orthologs in non-Dipteran Insects (EOG647DPF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB42458   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003255   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21482   Atta cephalotes Leafcutter ant  Acep\ACEP16201   Camponotus floridanus Florida carpenter ant  Cflo\CFLO18669   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22276   Linepithema humile Argentine ant  Lhum\LH19719   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25040   Solenopsis invicta Red fire ant  Sinv\SINV25514   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002294   Bombyx mori Silkmoth  Bmor\BGIBMGA011804   Pediculus humanus Human body louse  Phum\PHUM519450   Tribolium castaneum Red flour beetle  Tcas\TC003675
Orthologs in non-Insect Arthropods (EOG6QFTVF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_190766   Ixodes scapularis Deer tick  Isca\ISCW004895
Orthologs in non-Arthropod Metazoa (EOG6F28W9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000786gn   Danio rerio Zebrafish  Drer\ddx20   Xenopus tropicalis Western clawed frog  Xtro\ddx20   Gallus gallus Domestic chicken  Ggal\DDX20   Mus musculus House mouse  Mmus\Ddx20   Rattus norvegicus Norway rat  Rnor\Ddx20   Homo sapiens Human  Hsap\DDX20
Human Orthologs (1)
Gene OMIM HGNC Hsap\DDX20
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12861 Drosophila sechellia Dsec\GM24810 Drosophila erecta Dere\GG13972 Drosophila yakuba Dyak\GE20271 Drosophila ananassae Dana\GF23832 Drosophila pseudoobscura pseudoobscura Dpse\GA23460 Drosophila persimilis Dper\GL15598 Drosophila willistoni Dwil\GK24052 Drosophila virilis Dvir\GJ11703 Drosophila mojavensis Dmoj\GI13838 Drosophila grimshawi Dgri\GH16548
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	12079 P{PZ}Gem3rL562 ry506/TM3, Sb1 33408 y1 sc* v1; P{TRiP.HMS00287}attP2
Harvard	- PBac{?RB}Gem3e03688
VDRC	v49505 w1118 P{GD17221}v49505 v49506 w1118; P{GD17221}v49506 v7154 w1118; P{GD1417}v7154/TM3
Genomic Clones ( 2 )
	BACR01K09 BACR05G01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 37 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD05563
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE13311 RE15073 RE46348 SD07936
Other clones	79352 EK165361 EK208930 LD08132 RP003023231 RP003047271 RP003093536 RP003115492 RP003145305 RP003167396 RP003223406 RP003265462 RP003295789 RP003320967 RP003348960 RP003381841 RP003419541 RP003433090 RP003444791 RP003459610 RP003481738 RP003499994 RP003507966 RP003508454 RP003515030 RP003550078 RP003560665 RP003588818 RP003593511 RP003596008 RP003622454 SD02407
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0011802 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39195
Antibody Information
	polyclonal (Cauchi et al., 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	FlyBase curator comment: The gene corresponding to the CG6539 annotation was previously named "Dhh1" in FlyBase based on information in FBrf0125024, where the yeast Dhh1 protein is given as a homolog of CG6539. However, although the CG6539 does show some similarity to the yeast Dhh1 protein, the Drosophila ortholog of Dhh1 is the CG4916 annotation. Thus, to avoid confusion, the gene corresponding to the CG6539 annotation has been renamed to "Gem3, Gemin3" in FlyBase, as suggested in FBrf0206864. (Shpargel et al., 2009)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079295 NM_001274749 RefSeq (Proteins) • NP_524019 NP_001261678 DDBJ / EMBL / GenBank • AA246642 AAD46851 AAF50157 AF160911 AGB94372 AQ026370 Entrez Gene - A searchable database of RefSeq genes. • 39195 UniProtKB/TrEMBL • Q9V3C4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) RNA helicase, DEAD-box type, Q motif (IPR014014) P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64576 DroID - A comprehensive database of gene and protein interactions. • FBgn0011802 DRSC - Results from RNAi screens. • FBgn0011802 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0011802 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6539-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0011802 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39195 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39195 modMine - Data generated by the modENCODE project. • FBgn0011802
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	BcDNA:LD05563   BcDNA.LD05563 (Tsang, 1999.6.19) CG6539 (Shpargel et al., 2009, Cauchi et al., 2008, Gandhi et al., 2007, Cauchi et al., 2010, Ni et al., 2010.12.1) dGem3 (Shpargel et al., 2009) DHH1 (Boudet et al., 2001) Dhh1 (Cauchi et al., 2008, Kroiss et al., 2008) DmRH22 (Boudet et al., 2001) Gem3 (Shpargel et al., 2009, ) l(3)rL562 (Beaton, 2000.1.31, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999, )
Name Synonym	DEAD/DEAH RNA helicase 1 (Spradling et al., 1999) dGemin3 (Shpargel et al., 2009) Gemin3 (Buckingham and Liu, 2011, Shpargel et al., 2009, Kroiss et al., 2009, Kroiss et al., 2008, Cauchi et al., 2010, Cauchi, 2011) gemin3 (Cauchi et al., 2008)
Secondary FlyBase IDs
	FBgn0027895
References ( 30 )
Generate a list of	All references relating to this gene ( 30 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 3 )
	Cauchi, 2012, BMC Res. Notes 5: 120 Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis. [FBrf0218608] Buckingham and Liu, 2011, Exp. Cell Res. 317(20): 2835--2844 U bodies respond to nutrient stress in Drosophila. [FBrf0216562] Cauchi, 2011, Cell Biol. Int. 35(12): 1233--1238 Gem formation upon constitutive Gemin3 overexpression in Drosophila. [FBrf0216668] Show all research papers ...