Gene model reviewed during 5.46
Pseudogene similar to Lcp1; proximate; created by tandem duplication.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lcp1Ψ using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Lcp1Ψ in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New annotation (CR30367) in release 3 of the genome annotation.
Estimates of heterozygosity per nucleotide are lower that the average for many functional loci, this may be explained as the Lcp genes lie in a region of relatively low recombination. Low levels of within species polymorphism were unexpected due to the large number of nonsynonymous and synonymous substitutions between the pseudogene and parental genes. It is suggested that this low level of polymorphism results from genetic hitchiking due to directional selection at linked loci or from background selection against slightly deleterious alleles at linked sites.