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Gene Dana\B-H1

General Information
Symbol	Dana\B-H1	Species	D. ananassae
Name	BarH1	Annotation symbol	GF22335
Feature type	protein_coding_gene	FlyBase ID	FBgn0012114
Gene Model Status	Current	Stock availability	None publicly available
Also Known As	Om(1D)
Genomic Location
Chromosome (arm)	scaffold_13248	Recombination map	1-
Cytogenetic map		Sequence location	scaffold_13248:3,147,441..3,256,750 [-]
Genomic Maps	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene BarH1 is referred to in FlyBase by the symbol Dana\B-H1 (GF22335, FBgn0012114). It is a protein_coding_gene from Drosophila ananassae. An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of transcription, DNA-dependent. 22 alleles are reported. The phenotypes of these alleles are annotated with: ommatidium; morphogenetic furrow; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain-like. Gene sequence location is scaffold_13248:3147441..3256750.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	1-
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dana\B-H1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Dana\B-H1-RA FBtr0127035  XM_001965627   2832   943
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Dana\B-H1-PA   FBpp0125527   99.3   943   7.26     XP_001965663   EDV35178
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Homeobox, conserved site (IPR017970) Homeodomain (IPR001356) Homeodomain-like (IPR009057)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AY710106   AY710107   AY710108   AY710109   AY710110   AY710111   AY710112   AY710113   AY710114   AY710115   AY710116   AY710117   AY710118   AY710119   AY710120   AY710121   AY710122   AY710123   AY710124   AY710125   AY710126   AY710127   AY710128   AY710129   AY710130   AY710131   AY710132   AY710133   AY710134   AY710135   AY710136   AY710137   AY710138   AY710139   AY710140   AY710141   AY710142   AY710143   AY710144   AY710145   AY710146   AY710147   AY710148   AY710149   AY710150   AY710151   AY710152   AY710153   AY710154   AY710155   AY710156   AY710157   AY710158   AY710159   AY710160   AY710161   AY710162   AY710163   AY710164   AY710165   AY710166   AY710167   AY710168   AY710169   AY710170   AY710171   AY710172   AY710173   AY710174   AY710175   AY710176   AY710177   AY710178   AY710179   AY710180   AY710181   AY710182   AY710183   AY710184   AY710185   AY710186   AY710187   AY710188   AY710189   AY710190   AY710191   AY710192   AY710193   AY710194   AY710195   AY710196   AY710197   AY710198   AY710199   AY710200   AY710201   AY710202   AY710203   AY710204   AY710205   AY710206   AY710207   AY710208   AY710209   AY710210   AY710211   AY710212   AY710213   AY710214   AY710215   AY710216   AY710217   AY710218   AY710219   AY710220   AY710221   AY710222   AY710223   AY710224   AY710225   AY710226   AY710227   AY710228   AY710229   AY710230   AY710231   AY710232   AY710233   AY710234   AY710235   AY710236   AY710237   AY710238   AY710239   AY710240   AY710241   AY710242   AY710243   AY710244   AY710245   AY710246   AY710247   AY710248   AY710249   AY710250   AY710251   AY710252   AY710253   AY710254   AY710255   AY710256   AY710257   AY710258   AY710259   AY710260   AY710261   AY710262   AY710263   AY710264   AY710265   AY710266   CH902625 EDV35178   M59962   M59963 AAA28381   X56682 CAA40011
UniProtKB/Swiss-Prot	P22544
UniProtKB/TrEMBL	B3MW33
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | recessive Dana\B-H173R1 Other Phenotypes Allele visible Dana\B-H19 Dana\B-H1hs.PT visible | dominant Dana\B-H19e Dana\B-H1hs.PT visible | semidominant Dana\B-H173 visual behavior defective Dana\B-H12 Dana\B-H15 Dana\B-H19 Dana\B-H19b Dana\B-H19e Dana\B-H19g Dana\B-H116 Dana\B-H130 Dana\B-H136 Dana\B-H145 Dana\B-H148 Phenotype manifest in Allele eye Dana\B-H116 Dana\B-H12 Dana\B-H130 Dana\B-H136 Dana\B-H145 Dana\B-H148 Dana\B-H15 Dana\B-H173 Dana\B-H19 Dana\B-H19b Dana\B-H19e Dana\B-H19g morphogenetic furrow Dana\B-H1hs.PT ommatidium Dana\B-H19e Dana\B-H1hs.PT
Classical Alleles ( 21 )
For All Classical Alleles Show
Allele of Dana\B-H1 Class Mutagen Stocks Known lesion Dana\B-H116 0 -- Dana\B-H12 0 -- Dana\B-H130 0 -- Dana\B-H136 0 -- Dana\B-H145 0 -- Dana\B-H148 0 -- Dana\B-H158 0 -- Dana\B-H15 0 -- Dana\B-H15b 0 -- Dana\B-H173 neomorphic allele - genetic evidence spontaneous 0 Yes Dana\B-H173R1 0 -- Dana\B-H192 0 -- Dana\B-H196 0 -- Dana\B-H19 neomorphic allele - genetic evidence spontaneous 0 Yes Dana\B-H19b 0 -- Dana\B-H19e spontaneous 0 Yes Dana\B-H19g 0 -- Dana\B-H19R25 0 -- Dana\B-H19R64 0 -- Dana\B-H19R98 0 -- Dana\B-H1unspecified 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Dana\B-H1 Class Mutagen Stocks Known lesion Dana\B-H1hs.PT in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Dana\In(1)B-H1-9R64 (Tanda et al., 1993) Dana\In(1)B-H1-73R1 (Tanda et al., 1993)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
sequence-specific DNA binding inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 (FlyBase Curators et al., 2004-) sequence-specific DNA binding transcription factor activity inferred from electronic annotation with InterPro:IPR001356 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR012287, InterPro:IPR017970 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
nucleus inferred from electronic annotation with InterPro:IPR017970 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene (Drosophila 12 Genomes Consortium, 2008) protein_coding_gene (Drosophila 12 Genomes Consortium, 2008)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Dana\B-H1 allele Gene References Dana\B-H19 Dana\Om(1J)Su (Hinton, 1988) Dana\Om(1K)Su (Hinton, 1988) Dana\B-H1unspecified Dana\E(Om1D) (Tanda et al., 1993)
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (1) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila melanogaster Dmel\B-H1
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
	Hinton, 1981, 1982, 1983.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Genetically mapped, but location given in terms of cytology as 15B. (Matsubayashi et al., 1992) Polypeptides from B-H1 of D.melanogaster and Dana\B-H1 of D.ananassae have homeodomains identical in sequence except for one amino acid replacement: the conserved Phe in helix 3 is replaced by Tyr. (Kojima et al., 1991) May be homologous to the Bar gene of D.melanogaster. (Tanda and Corces, 1991) Identification: Mutants for defective optic morphology, identified during study of a hypermutable system. (Hinton, 1984) Considerable quantitative variation between the 11 mutants. Eye tissue reductions accompanied by more or less prominent anterior indentation and by jumbled ommatidia around the indentations; orthogonal arrays of ommatidia seen beyond the indentation.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • XM_001965627 RefSeq (Proteins) • XP_001965663 DDBJ / EMBL / GenBank • AAA28381 AY710106 AY710107 AY710108 AY710109 AY710110 AY710111 AY710112 AY710113 AY710114 AY710115 AY710116 AY710117 AY710118 AY710119 AY710120 AY710121 AY710122 AY710123 AY710124 AY710125 AY710126 AY710127 AY710128 AY710129 AY710130 AY710131 AY710132 AY710133 AY710134 AY710135 AY710136 AY710137 AY710138 AY710139 AY710140 AY710141 AY710142 AY710143 AY710144 AY710145 AY710146 AY710147 AY710148 AY710149 AY710150 AY710151 AY710152 AY710153 AY710154 AY710155 AY710156 AY710157 AY710158 AY710159 AY710160 AY710161 AY710162 AY710163 AY710164 AY710165 AY710166 AY710167 AY710168 AY710169 AY710170 AY710171 AY710172 AY710173 AY710174 AY710175 AY710176 AY710177 AY710178 AY710179 AY710180 AY710181 AY710182 AY710183 AY710184 AY710185 AY710186 AY710187 AY710188 AY710189 AY710190 AY710191 AY710192 AY710193 AY710194 AY710195 AY710196 AY710197 AY710198 AY710199 AY710200 AY710201 AY710202 AY710203 AY710204 AY710205 AY710206 AY710207 AY710208 AY710209 AY710210 AY710211 AY710212 AY710213 AY710214 AY710215 AY710216 AY710217 AY710218 AY710219 AY710220 AY710221 AY710222 AY710223 AY710224 AY710225 AY710226 AY710227 AY710228 AY710229 AY710230 AY710231 AY710232 AY710233 AY710234 AY710235 AY710236 AY710237 AY710238 AY710239 AY710240 AY710241 AY710242 AY710243 AY710244 AY710245 AY710246 AY710247 AY710248 AY710249 AY710250 AY710251 AY710252 AY710253 AY710254 AY710255 AY710256 AY710257 AY710258 AY710259 AY710260 AY710261 AY710262 AY710263 AY710264 AY710265 AY710266 CAA40011 EDV35178 M59962 M59963 X56682 Entrez Gene - A searchable database of RefSeq genes. • 6492915 UniProtKB/Swiss-Prot • P22544 UniProtKB/TrEMBL • B3MW33
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Homeobox, conserved site (IPR017970) Homeodomain (IPR001356) Homeodomain-like (IPR009057)
Linkouts
	FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0012114
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	B-H1 (Drosophila 12 Genomes Consortium, 2008) dana_GLEANR_6309 (Drosophila 12 Genomes Consortium, 2008) Dana\B   Dana\B-H1 (Drosophila 12 Genomes Consortium, 2008) Dana\Om(1D)   Om(1D) (Stephan et al., 1998, Tanda and Corces, 1991, Matsubayashi et al., 1992, Kojima et al., 1991, Tanda and Corces, 1991, Hinton, 1988)
Name Synonym	Bar   BarH1 (FlyBase Curators, 2008) Optic morphology(1D) (Matsubayashi et al., 1992, )
Secondary FlyBase IDs
	FBgn0012122
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 14 ) Review  ( 3 ) Personal communication to FlyBase  ( 2 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Letter  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...