A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Gene Dmel\Gp150

General Information
SymbolDmel\Gp150SpeciesD. melanogaster
NameGp150Annotation symbolCG5820
Feature typeprotein_coding_geneFlyBase IDFBgn0013272
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)2RRecombination map2-
Cytogenetic map 58D3-58D3 Sequence location2R:18,205,167..18,216,933 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol Gp150 (CG5820, FBgn0013272). It has the cytological map location 58D3. Its sequence location is 2R:18205167..18216933. Its molecular function is described as: ATP binding; catalytic activity; protein binding. It is involved in the biological processes: transmembrane receptor protein tyrosine phosphatase signaling pathway; compound eye development; metabolic process. 25 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult; adult segment; adult mesothoracic segment; thoracic segment; sense organ; eye; anterior scutellar bristle. It has 4 annotated transcripts and 4 annotated polypeptides.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
58D3-58D3  
Limits computationally determined from genome sequence between P{PZ}ari-207768 and P{lacW}l(2)k09801k09801  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
58D1-58D3
58D1-58D8
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
Overall orientation not stated: Gp150+ pgc+ T3dh- pgc+
Overall orientation not stated: Gp150+ T3dh-
hide Gene Model & Products
Please see the GBrowse view of Dmel\Gp150 for information on other features
detailed view FBtr0071813 FBtr0071814 FBtr0071815 FBtr0071816 FBtr0112400 FBtr0112519 FBtr0112520 FBtr0071848 FBpp0071729 FBpp0071728 FBpp0071727 FBpp0071726 FBpp0111315 FBpp0071759 FBti0040077 FBti0054529 FBti0055952 FBti0018535 FBti0035899
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0071813
  4228
  1051
FBtr0071814
  4256
  1051
FBtr0071815
  4355
  1051
FBtr0071816
  4202
  1076
Additional Transcript Data & Comments
Reported size (kB)
4.5 (northern blot)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0071726  
118.2  
1051  
4.56  
FBpp0071727  
118.2  
1051  
4.56  
FBpp0071728  
118.2  
1051  
4.56  
FBpp0071729  
121.0  
1076  
4.62  
Additional Polypeptide Data & Comments
Reported size (kD)
1051 (aa); 150 (kD observed); 115 (kD predicted)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    deletion
    comment=A 1305bp deletion from exon 5 into exon 6. The deletion extends from amino acid 620 to 1040 and is followed by a frameshift and translation termination a few residues later.
    evidence=experimental
    point mutation
    comment=G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified).
    evidence=experimental
    pr_change=W119|Gp150-PD,W94|Gp150-PB,W94|Gp150-PC, W94 |Gp150-PA
    reported_na_change=G?A
    reported_pr_change=W94@
    transposable element target site duplication
    comment=Position of 8bp P element repeat based on author statement that insertion maps 53bp into the 2nd intron of Gp150.
    evidence=experimental
    transposable element target site duplication
    P{GawB}Gp150[52A]
    2R:18,205,629..18,205,636
    comment=Location of 8bp P element repeat based on author statement that insertion maps 170bp into the 2nd intron of Gp150.
    evidence=experimental
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data
    Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
     embryonic stage
     embryonic stage
     embryonic stage | stage 3-12
     embryonic stage | stage 10-12
     ventral midline
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
       larval stage
       eye disc
      Marker for
        Subcellular Localization
        CV Term
        plasma membrane
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array