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Gene Dmel\Gp150

General Information
Symbol	Dmel\Gp150	Species	D. melanogaster
Name	Gp150	Annotation symbol	CG5820
Feature type	protein_coding_gene	FlyBase ID	FBgn0013272
Gene Model Status	Current	Stock availability	11 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map	2-
Cytogenetic map	58D3-58D3	Sequence location	2R:18,205,167..18,216,921 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Gp150 is referred to in FlyBase by the symbol Dmel\Gp150 (CG5820, FBgn0013272). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; transmembrane receptor protein tyrosine phosphatase signaling pathway; compound eye development. 31 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; external compound sense organ; adult segment; organ system; peripheral nervous system; histaminergic neuron; thoracic segment; eo support cell; adult; anterior scutellar bristle; wing margin bristle. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval fat body, adult ovary, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1631569_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of Gp150. Gene sequence location is 2R:18205167..18216933.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Polypeptides Gp150-PE Gp150-PF Transcripts Gp150-RE Gp150-RF
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 58D3-58D3   Limits computationally determined from genome sequence between P{PZ}ari-207768 and P{lacW}l(2)k09801k09801
Experimentally Determined Cytological Location
Cytogenetic map Notes References 58D1-58D3     (Zinn, 1994.9.28) 58D1-58D8     (Nakamura, 1996.8.8)
Experimentally Determined Recombination Data
Location	2- (Zhou et al., 1997, Nakamura, 1996.8.8, Zinn, 1994.9.28)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Gp150 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Gp150-RA FBtr0071813  NM_166527   4216   1051 Gp150-RB FBtr0071814  NM_166528   4255   1051 Gp150-RC FBtr0071815  NM_166529   4360   1051 Gp150-RD FBtr0071816  NM_057701   4190   1076 Gp150-RE FBtr0342985     4422   1044 Gp150-RF FBtr0342986     4124   1051
Additional Transcript Data & Comments
Reported size (kB)	4.5 (northern blot) (Tian and Zinn, 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Gp150-PA   FBpp0071726   118.2   1051   4.56     NP_726190   AAF46831 Gp150-PB   FBpp0071727   118.2   1051   4.56     NP_726191   AAM68222 Gp150-PC   FBpp0071728   118.2   1051   4.56     NP_726192   AAG22195 Gp150-PD   FBpp0071729   121.0   1076   4.62     NP_477049   AAM68221 Gp150-PE   FBpp0309749   117.4   1044   4.54       Gp150-PF   FBpp0309750   118.2   1051   4.56
Additional Polypeptide Data & Comments
Reported size (kDa)	1051 (aa); 150 (kD observed); 115 (kD predicted) (Tian and Zinn, 1994)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Leucine-rich repeat (IPR001611) Leucine-rich repeat, typical subtype (IPR003591)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141523   AA141524   AA433234   AA694992   AA695579   AA802858   AA803395   AE013599 AAF46831   AE013599 AAG22195   AE013599 AAM68221   AE013599 AAM68222   AC005714   AI063579   AI108778   AI114003   AI257665   AI258365   AI296024   AI296937   AI387658   AI403748   AI405711   AI513802   AI514660   AI531690   AI533819   AI534088   AI535027   AY029705 AAK39644   BG637198   BG641303   BI142246   BI167440   BI169877   BI172673   BI173263   BI212454   BI212602   BI215505   BI227740   BI227871   BI228686   BI229545   BI230390   BI231232   BI232051   BI233082   BI234109   BI235035   BI235427   BI235761   BI236207   BI236607   BI239185   BI239272   BI239345   BI240430   BI240488   BI241817   BI241962   BI352191   BI352530   BI356210   BI357302   BI357383   BI357408   BI357542   BI357587   BI358334   BI361681   BI361785   BI361930   BI363313   BI366491   BI367104   BI368637   BI369630   BI370038   BI370210   BI371064   BI371544   BI372533   BI374142   BI481797   BI482683   BI484215   BI484573   BI484711   BI486843   BI487042   BI578379   BI579837   BI580505   BP540658   BP541351   BP548998   BP549913   BP556492   BP557614   BP559555   BP560123   BT011025   BT015195 AAT94424   BT125768   CA805085   CK657050   CK657070   CK657243   CK659935   CK660564   CO176766   CO181408   CO195769   CO196184   CO263227   CO263790   CO265960   CO266708   CO269755   CO269877   CO270290   CO277163   CO277244   CO277288   CO280867   CO290309   CO298953   CO305891   CO306095   CO308201   CO309498   CO311072   CO313315   CO314016   CO317398   CO320671   CO323871   CO324482   CO332665   CO333077   CO338455   CO342448   DN154227   EC060783   EC070396   EC072411   EC073394   EC075026   EC075165   EC079610   EC082135   EC083184   EC086281   EC088072   EC090649   EC194656   EC195250   EC197319   EC199229   EC200159   EC200294   EC202783   EC203335   EC204758   EC209116   EC213518   EC214045   EC214796   EC221867   EC221908   EC223317   EC223708   EC224066   EC228273   EC230795   EC231834   EC232247   EC234358   EC238621   EC238747   EC243214   EC244946   EC247864   EC249416   EC250519   EC254848   EC266228   ES696627   GH748028   GH748903   GH749367   GH749494   GH749942   GH750051   GH750987   GH751225   GH751578   GH752301   GH752879   GH753724   GH754615   GH755256   GH757581   GH757875   GH758112   GH758329   GH759495   GH759556   GH759638   GH760338   GH760595   GH760659   GH760721   GH770320   GH770326   GH770577   GH771460   GH771607   GH771673   GH772166   GH772618   GH772840   GH772993   GH773319   GH773329   GH774393   GH775063   GH775436   GH775563   GH775993   GH776045   GH776926   GH777394   GH777929   GH778242   GH778836   GH779095   GH779122   GH780093   GH780239   GH780385   GH780561   GH781062   GH781539   GH781828   GH782162   GH782341   GH782361   GH782566   GH782853   GH783226   GH783777   GH784741   GH784931   GH785959   GH786435   GH787829   GH788815   GH788883   GH789281   GH789291   GH791512   GH792627   GH792773   GH792781   GH793199   GH793448   GH793700   GH795357   GH795359   GH796318   GH796645   GH797453   GH797742   GH798256   GH798804   GH798875   GH799116   GH799460   GH799557   GH799565   GH800470   GH801164   GH801419   GH801842   GH802105   GH802389   GH802547   GH803104   GH803125   GH803429   GH805564   GH806738   GH807619   GH807622   GH808284   GH808523   GH809837   GH810226   GH810464   GH810570   GH811173   GH811390   GH811573   GH812938   GH813095   GH813856   GH813944   GH814525   GH814679   GH815340   GH816573   GH816640   GH817049   GH817842   GH817990   GH818682   GH819019   GH819327   GH819369   GH819526   GH820508   GH820586   GH821277   GH821402   GH821463   GH821515   GH822827   GH823009   GH823320   GH823410   GH823653   GH824188   GH824272   GH824596   GH824846   GH825129   GH826375   GH826539   GH827948   GH828041   GH829723   GH831408   GH833534   GH834190   GH834859   GH836899   GH837722   GH837753   GH838530   GH839301   GH839399   GH839618   GH840104   GH840365   GH840711   GH841292   GH841374   GH841556   GH841779   GH842252   GH842755   GH843119   GH843631   GH844663   GH844799   GH844886   GH844966   GH844997   GH845079   GH845203   GH845233   GH845255   GH845497   GH846375   GH846745   GH846748   GH847074   GH848160   GH848576   GH848892   GH849856   GH849903   GH851605   GH853384   GH853475   GH853556   GH854357   GH854430   GH854964   GH855425   GH855480   GH855797   GH857832   GH857974   GH858158   GH858749   GH859805   GH859875   GH860141   GH860622   GH860629   GH860794   GH861935   GH862019   GH862709   GH863651   GH863941   GH863975   GH865087   GH865105   GH865300   GH865378   GH865648   GH865891   GH866077   GH866222   GH866463   GH866551   GH866724   GH867692   GH868373   GH868685   GH868971   GH869301   GH869731   GH870351   GH870377   GH870672   GH872503   GH872646   GH873670   GH873986   GH874052   GH874517   GH874836   GH874895   GH875681   GH876205   GH877121   GH877583   GH877647   GH877910   GH879240   GH879323   GH879957   GH880232   GH881524   GH881692   GH882599   GH883023   GH883553   GH883762   GH884601   GH885346   GH885624   GH885812   GH885925   GH886926   GH887512   GH887548   GH888374   GH888573   GH888670   GH888897   GH889236   GH889901   GH890553   GH891023   GH891183   GH891471   GH891749   GH891831   GH891857   GH891874   GH892605   GH892653   GH893369   GH894924   GH894934   GH895035   GH895155   GH895246   GH895263   GH895543   GH896678   GH896874   GH896942   GH897526   GH898226   GH898662   GH898695   GH898957   GH899747   GH900266   GH901296   GH902401   GH904122   GH904268   GH904395   GH904459   GH905601   GH906115   GH906257   GH906359   GH906427   GH906627   GH907950   GH908156   GH908389   GH908411   GH908851   GH909064   GH909295   GH909554   GH910312   GH910379   GH910942   GH911595   GH911855   GH911962   GH912712   GH912813   GH913404   GH913917   GH913983   GH914298   GH914400   GH914916   GH914986   GH915244   GH915846   GH916339   GH916388   GH916606   GH917455   GH917520   GH919263   GH919452   GH920229   GH920288   GH920868   GH920967   GH921026   GH921874   GH921913   GH922163   GH922475   GH922492   GH923472   GH923723   GH924234   GH924364   GH924869   GH924922   GH925017   GH925618   GH926238   GH926624   GH926917   GH927918   GH928027   GH929160   GH929752   GH930382   GH931256   GH931665   GH931843   GH932031   GH932478   GH932572   GH933093   GH933756   GH933759   GH934807   GH934847   GH935666   GH936095   GH939598   GH940028   GH940152   GH940243   GH940420   GH940566   GH940646   U15220 AAA61796   U66411 AAB71081   Z50242
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q24007 Q8MLT4 Q95PA9 Q7JNM8 Q6AWQ3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage   epithelial cell   • cytoplasm | apical (Lecuyer et al., 2007) Comment:clustered apical distribution epithelium   • cytoplasm | apical (Lecuyer et al., 2007) neuroblast   (Lecuyer et al., 2007) Comment:asymetrically distributed embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   dorsal epidermis primordium   (Fisher et al., 2012) ventral epidermis primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic dorsal epidermis   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Tian and Zinn, 1994) organism | segmentally repeated   (Tian and Zinn, 1994) embryonic stage 3 -- 12     (Tian and Zinn, 1994) embryonic stage 10 -- 12   ventral midline   (Tian and Zinn, 1994)
Additional Descriptive Data
	Gp150 transcripts are most abundant between 3 and 12 hours of embryogenesis. Gp150 transcripts are expressed in most or all cells of the embryo. Elevated levels are observed along the ventral midline and in segmentally repeated lateral patches in the epithelium. At stage 12, expression is observed in stripes located just posterior to the segmental grooves. (Tian and Zinn, 1994)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference larval stage   eye disc   • late endosome (Li et al., 2003)
Additional Descriptive Data
	Both sca and Gp150 protein were detected in late endosomes in eye discs. sca protein was frequently found in large particles in these endosomes. (Li et al., 2003)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
plasma membrane inferred from direct assay (Tian and Zinn, 1994)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval fat body, adult ovary, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut    3168.2 Larval Hindgut    3999.6 Larval Malpighian Tubules    4376.8 Larval Fat Body    492.9 Larval Salivary Gland    2625.2 Larval Trachea    3791.975 Larval Carcass    1811.1 Adult Head    1755.2 Adult Eye    2352.775 Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop    3956.5 Adult Midgut    3002.5 Adult Hindgut    4162.9 Adult Malpighian Tubules    4285.4 Adult Fat Body    2899.2 Adult Salivary Gland    4531 Adult Heart    3411.575 Adult VirginFemale Spermatheca    4151.9 Adult InseminatedFemale Spermatheca    3208.3 Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass    2113 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (664.625) Larval Midgut  (3168.2) Larval Hindgut  (3999.6) Larval Malpighian Tubules  (4376.8) Larval Fat Body    492.9 Larval Salivary Gland  (2625.2) Larval Trachea  (3791.975) Larval Carcass  (1811.1) Adult Head  (1755.2) Adult Eye  (2352.775) Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop  (3956.5) Adult Midgut  (3002.5) Adult Hindgut  (4162.9) Adult Malpighian Tubules  (4285.4) Adult Fat Body  (2899.2) Adult Salivary Gland  (4531) Adult Heart  (3411.575) Adult VirginFemale Spermatheca  (4151.9) Adult InseminatedFemale Spermatheca  (3208.3) Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass  (2113) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut  (3168.2) Larval Hindgut  (3999.6) Larval Malpighian Tubules  (4376.8) Larval Fat Body    492.9 Larval Salivary Gland  (2625.2) Larval Trachea  (3791.975) Larval Carcass  (1811.1) Adult Head  (1755.2) Adult Eye  (2352.775) Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop  (3956.5) Adult Midgut  (3002.5) Adult Hindgut  (4162.9) Adult Malpighian Tubules  (4285.4) Adult Fat Body  (2899.2) Adult Salivary Gland  (4531) Adult Heart  (3411.575) Adult VirginFemale Spermatheca  (4151.9) Adult InseminatedFemale Spermatheca  (3208.3) Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass  (2113) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut    3168.2 Larval Hindgut    3999.6 Larval Malpighian Tubules    4376.8 Larval Fat Body    492.9 Larval Salivary Gland    2625.2 Larval Trachea    3791.975 Larval Carcass    1811.1 Adult Head    1755.2 Adult Eye    2352.775 Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop    3956.5 Adult Midgut    3002.5 Adult Hindgut    4162.9 Adult Malpighian Tubules    4285.4 Adult Fat Body    2899.2 Adult Salivary Gland    4531 Adult Heart    3411.575 Adult VirginFemale Spermatheca    4151.9 Adult InseminatedFemale Spermatheca    3208.3 Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass    2113 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut    3168.2 Larval Hindgut    3999.6 Larval Malpighian Tubules    4376.8 Larval Fat Body    492.9 Larval Salivary Gland    2625.2 Larval Trachea    3791.975 Larval Carcass    1811.1 Adult Head    1755.2 Adult Eye    2352.775 Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop    3956.5 Adult Midgut    3002.5 Adult Hindgut    4162.9 Adult Malpighian Tubules    4285.4 Adult Fat Body    2899.2 Adult Salivary Gland    4531 Adult Heart    3411.575 Adult VirginFemale Spermatheca    4151.9 Adult InseminatedFemale Spermatheca    3208.3 Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass    2113 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  664.625 Larval Midgut  (3168.2) Larval Hindgut  (3999.6) Larval Malpighian Tubules  (4376.8) Larval Fat Body    492.9 Larval Salivary Gland  (2625.2) Larval Trachea  (3791.975) Larval Carcass  (1811.1) Adult Head  (1755.2) Adult Eye  (2352.775) Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop  (3956.5) Adult Midgut  (3002.5) Adult Hindgut  (4162.9) Adult Malpighian Tubules  (4285.4) Adult Fat Body  (2899.2) Adult Salivary Gland  (4531) Adult Heart  (3411.575) Adult VirginFemale Spermatheca  (4151.9) Adult InseminatedFemale Spermatheca  (3208.3) Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass  (2113) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut  (3168.2) Larval Hindgut  (3999.6) Larval Malpighian Tubules  (4376.8) Larval Fat Body    492.9 Larval Salivary Gland  (2625.2) Larval Trachea  (3791.975) Larval Carcass  (1811.1) Adult Head  (1755.2) Adult Eye  (2352.775) Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop  (3956.5) Adult Midgut  (3002.5) Adult Hindgut  (4162.9) Adult Malpighian Tubules  (4285.4) Adult Fat Body  (2899.2) Adult Salivary Gland  (4531) Adult Heart  (3411.575) Adult VirginFemale Spermatheca  (4151.9) Adult InseminatedFemale Spermatheca  (3208.3) Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass  (2113) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    664.625 Larval Midgut    3168.2 Larval Hindgut    3999.6 Larval Malpighian Tubules    4376.8 Larval Fat Body    492.9 Larval Salivary Gland    2625.2 Larval Trachea    3791.975 Larval Carcass    1811.1 Adult Head    1755.2 Adult Eye    2352.775 Adult Brain    241.3 Adult Thoracic-Abdominal Ganglion    242 Adult Crop    3956.5 Adult Midgut    3002.5 Adult Hindgut    4162.9 Adult Malpighian Tubules    4285.4 Adult Fat Body    2899.2 Adult Salivary Gland    4531 Adult Heart    3411.575 Adult VirginFemale Spermatheca    4151.9 Adult InseminatedFemale Spermatheca    3208.3 Adult Ovary    446.4 Adult Testis    378.2 Adult Male Accessory Gland    230.1 Adult Carcass    2113 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1755.2   NA  Eye    2352.775   NA  Brain    241.3   664.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    242   NA  Crop    3956.5   3168.2  Midgut    3002.5   3999.6  Hindgut    4162.9   4376.8  Malpighian Tubules    4285.4   492.9  Fat Body    2899.2   2625.2  Salivary Gland    4531   NA  Heart    3411.575   3791.975  Trachea    NA   NA  VirginFemale Spermatheca    4151.9   NA  InseminatedFemale Spermatheca    3208.3   NA  Ovary    446.4   NA  Testis    378.2   NA  Male Accessory Gland    230.1   1811.1  Carcass    2113 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    226 central nervous system, larvae L3    101 central nervous system, pupae P8    66 head, virgin 1-day female    221 head, virgin 4-day female    194 head, virgin 20-day female    159 head, mated 1-day female    214 head, mated 4-day female    244 head, mated 20-day female    139 head, mated 1-day male    264 head, mated 4-day male    281 head, mated 20-day male    299 salivary gland, larvae L3 wandering    85 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    1004 digestive system, 1-day adult    314 digestive system, 4-day adult    361 digestive system, 20-day adult    389 fat body, larvae L3 wandering    32 fat body, white prepupae    103 fat body, pupae P8    122 carcass, larvae L3 wandering    352 carcass, 1-day adult    245 carcass, 4-day adult    267 carcass, 20-day adult    261 ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (226) central nervous system, larvae L3  (101) central nervous system, pupae P8  (66) head, virgin 1-day female  (221) head, virgin 4-day female  (194) head, virgin 20-day female  (159) head, mated 1-day female  (214) head, mated 4-day female  (244) head, mated 20-day female  (139) head, mated 1-day male  (264) head, mated 4-day male  (281) head, mated 20-day male  (299) salivary gland, larvae L3 wandering  (85) salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (1004) digestive system, 1-day adult  (314) digestive system, 4-day adult  (361) digestive system, 20-day adult  (389) fat body, larvae L3 wandering  (32) fat body, white prepupae  (103) fat body, pupae P8  (122) carcass, larvae L3 wandering  (352) carcass, 1-day adult  (245) carcass, 4-day adult  (267) carcass, 20-day adult  (261) ovary, virgin 4-day female  (44) ovary, mated 4-day female  (59) testis, mated 4-day male  (45) accessory gland, mated 4-day male  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (226) central nervous system, larvae L3  101 central nervous system, pupae P8    66 head, virgin 1-day female  (221) head, virgin 4-day female  (194) head, virgin 20-day female  (159) head, mated 1-day female  (214) head, mated 4-day female  (244) head, mated 20-day female  (139) head, mated 1-day male  (264) head, mated 4-day male  (281) head, mated 20-day male  (299) salivary gland, larvae L3 wandering    85 salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (1004) digestive system, 1-day adult  (314) digestive system, 4-day adult  (361) digestive system, 20-day adult  (389) fat body, larvae L3 wandering    32 fat body, white prepupae  103 fat body, pupae P8  (122) carcass, larvae L3 wandering  (352) carcass, 1-day adult  (245) carcass, 4-day adult  (267) carcass, 20-day adult  (261) ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    226 central nervous system, larvae L3    101 central nervous system, pupae P8    66 head, virgin 1-day female    221 head, virgin 4-day female    194 head, virgin 20-day female    159 head, mated 1-day female    214 head, mated 4-day female    244 head, mated 20-day female    139 head, mated 1-day male    264 head, mated 4-day male    281 head, mated 20-day male    299 salivary gland, larvae L3 wandering    85 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    1004 digestive system, 1-day adult    314 digestive system, 4-day adult    361 digestive system, 20-day adult    389 fat body, larvae L3 wandering    32 fat body, white prepupae    103 fat body, pupae P8    122 carcass, larvae L3 wandering    352 carcass, 1-day adult    245 carcass, 4-day adult    267 carcass, 20-day adult    261 ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    226 central nervous system, larvae L3    101 central nervous system, pupae P8    66 head, virgin 1-day female    221 head, virgin 4-day female    194 head, virgin 20-day female    159 head, mated 1-day female    214 head, mated 4-day female    244 head, mated 20-day female    139 head, mated 1-day male    264 head, mated 4-day male    281 head, mated 20-day male    299 salivary gland, larvae L3 wandering    85 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    1004 digestive system, 1-day adult    314 digestive system, 4-day adult    361 digestive system, 20-day adult    389 fat body, larvae L3 wandering    32 fat body, white prepupae    103 fat body, pupae P8    122 carcass, larvae L3 wandering    352 carcass, 1-day adult    245 carcass, 4-day adult    267 carcass, 20-day adult    261 ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (226) central nervous system, larvae L3  (101) central nervous system, pupae P8  (66) head, virgin 1-day female  (221) head, virgin 4-day female  (194) head, virgin 20-day female  (159) head, mated 1-day female  (214) head, mated 4-day female  (244) head, mated 20-day female  (139) head, mated 1-day male  (264) head, mated 4-day male  (281) head, mated 20-day male  (299) salivary gland, larvae L3 wandering  (85) salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (1004) digestive system, 1-day adult  (314) digestive system, 4-day adult  (361) digestive system, 20-day adult  (389) fat body, larvae L3 wandering  32 fat body, white prepupae  (103) fat body, pupae P8  (122) carcass, larvae L3 wandering  (352) carcass, 1-day adult  (245) carcass, 4-day adult  (267) carcass, 20-day adult  (261) ovary, virgin 4-day female  (44) ovary, mated 4-day female  (59) testis, mated 4-day male  (45) accessory gland, mated 4-day male  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (226) central nervous system, larvae L3  101 central nervous system, pupae P8    66 head, virgin 1-day female  (221) head, virgin 4-day female  (194) head, virgin 20-day female  (159) head, mated 1-day female  (214) head, mated 4-day female  (244) head, mated 20-day female  139 head, mated 1-day male  (264) head, mated 4-day male  (281) head, mated 20-day male  (299) salivary gland, larvae L3 wandering    85 salivary gland, white prepupae  (420) digestive system, larvae L3 wandering  (1004) digestive system, 1-day adult  (314) digestive system, 4-day adult  (361) digestive system, 20-day adult  (389) fat body, larvae L3 wandering    32 fat body, white prepupae  103 fat body, pupae P8  122 carcass, larvae L3 wandering  (352) carcass, 1-day adult  (245) carcass, 4-day adult  (267) carcass, 20-day adult  (261) ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    226 central nervous system, larvae L3    101 central nervous system, pupae P8    66 head, virgin 1-day female    221 head, virgin 4-day female    194 head, virgin 20-day female    159 head, mated 1-day female    214 head, mated 4-day female    244 head, mated 20-day female    139 head, mated 1-day male    264 head, mated 4-day male    281 head, mated 20-day male    299 salivary gland, larvae L3 wandering    85 salivary gland, white prepupae    420 digestive system, larvae L3 wandering    1004 digestive system, 1-day adult    314 digestive system, 4-day adult    361 digestive system, 20-day adult    389 fat body, larvae L3 wandering    32 fat body, white prepupae    103 fat body, pupae P8    122 carcass, larvae L3 wandering    352 carcass, 1-day adult    245 carcass, 4-day adult    267 carcass, 20-day adult    261 ovary, virgin 4-day female    44 ovary, mated 4-day female    59 testis, mated 4-day male    45 accessory gland, mated 4-day male    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    374 embryo 06-08hr    383 embryo 08-10hr    306 embryo 10-12hr    203 embryo 12-14hr    255 embryo 14-16hr    220 embryo 16-18hr    232 embryo 18-20hr    189 embryo 20-22hr    142 embryo 22-24hr    164 larva L1    95 larva L2    102 larva L3 12hr old    105 larva L3 puffstage 1-2    103 larva L3 puffstage 3-6    167 larva L3 puffstage 7-9    277 white prepupae new    398 white prepupae 12hr    305 white prepupae 24hr    165 pupae 2d postWPP    176 pupae 3d postWPP    121 pupae 4d postWPP    129 adult male 01day    151 adult male 05day    119 adult male 30day    95 adult female 01day    121 adult female 05day    79 adult female 30day    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  (109) embryo 04-06hr  (374) embryo 06-08hr  (383) embryo 08-10hr  (306) embryo 10-12hr  (203) embryo 12-14hr  (255) embryo 14-16hr  (220) embryo 16-18hr  (232) embryo 18-20hr  (189) embryo 20-22hr  (142) embryo 22-24hr  (164) larva L1  (95) larva L2  (102) larva L3 12hr old  (105) larva L3 puffstage 1-2  (103) larva L3 puffstage 3-6  (167) larva L3 puffstage 7-9  (277) white prepupae new  (398) white prepupae 12hr  (305) white prepupae 24hr  (165) pupae 2d postWPP  (176) pupae 3d postWPP  (121) pupae 4d postWPP  (129) adult male 01day  (151) adult male 05day  (119) adult male 30day  (95) adult female 01day  (121) adult female 05day  (79) adult female 30day  (69) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  (109) embryo 04-06hr  (374) embryo 06-08hr  (383) embryo 08-10hr  (306) embryo 10-12hr  (203) embryo 12-14hr  (255) embryo 14-16hr  (220) embryo 16-18hr  (232) embryo 18-20hr  (189) embryo 20-22hr  (142) embryo 22-24hr  (164) larva L1    95 larva L2  102 larva L3 12hr old  105 larva L3 puffstage 1-2  103 larva L3 puffstage 3-6  (167) larva L3 puffstage 7-9  (277) white prepupae new  (398) white prepupae 12hr  (305) white prepupae 24hr  (165) pupae 2d postWPP  (176) pupae 3d postWPP  (121) pupae 4d postWPP  (129) adult male 01day  (151) adult male 05day  (119) adult male 30day    95 adult female 01day  (121) adult female 05day    79 adult female 30day    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    374 embryo 06-08hr    383 embryo 08-10hr    306 embryo 10-12hr    203 embryo 12-14hr    255 embryo 14-16hr    220 embryo 16-18hr    232 embryo 18-20hr    189 embryo 20-22hr    142 embryo 22-24hr    164 larva L1    95 larva L2    102 larva L3 12hr old    105 larva L3 puffstage 1-2    103 larva L3 puffstage 3-6    167 larva L3 puffstage 7-9    277 white prepupae new    398 white prepupae 12hr    305 white prepupae 24hr    165 pupae 2d postWPP    176 pupae 3d postWPP    121 pupae 4d postWPP    129 adult male 01day    151 adult male 05day    119 adult male 30day    95 adult female 01day    121 adult female 05day    79 adult female 30day    69 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    374 embryo 06-08hr    383 embryo 08-10hr    306 embryo 10-12hr    203 embryo 12-14hr    255 embryo 14-16hr    220 embryo 16-18hr    232 embryo 18-20hr    189 embryo 20-22hr    142 embryo 22-24hr    164 larva L1    95 larva L2    102 larva L3 12hr old    105 larva L3 puffstage 1-2    103 larva L3 puffstage 3-6    167 larva L3 puffstage 7-9    277 white prepupae new    398 white prepupae 12hr    305 white prepupae 24hr    165 pupae 2d postWPP    176 pupae 3d postWPP    121 pupae 4d postWPP    129 adult male 01day    151 adult male 05day    119 adult male 30day    95 adult female 01day    121 adult female 05day    79 adult female 30day    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  (109) embryo 04-06hr  (374) embryo 06-08hr  (383) embryo 08-10hr  (306) embryo 10-12hr  (203) embryo 12-14hr  (255) embryo 14-16hr  (220) embryo 16-18hr  (232) embryo 18-20hr  (189) embryo 20-22hr  (142) embryo 22-24hr  (164) larva L1  (95) larva L2  (102) larva L3 12hr old  (105) larva L3 puffstage 1-2  (103) larva L3 puffstage 3-6  (167) larva L3 puffstage 7-9  (277) white prepupae new  (398) white prepupae 12hr  (305) white prepupae 24hr  (165) pupae 2d postWPP  (176) pupae 3d postWPP  (121) pupae 4d postWPP  (129) adult male 01day  (151) adult male 05day  (119) adult male 30day  (95) adult female 01day  (121) adult female 05day  (79) adult female 30day  (69) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  109 embryo 04-06hr  (374) embryo 06-08hr  (383) embryo 08-10hr  (306) embryo 10-12hr  (203) embryo 12-14hr  (255) embryo 14-16hr  (220) embryo 16-18hr  (232) embryo 18-20hr  (189) embryo 20-22hr  142 embryo 22-24hr  (164) larva L1    95 larva L2  102 larva L3 12hr old  105 larva L3 puffstage 1-2  103 larva L3 puffstage 3-6  (167) larva L3 puffstage 7-9  (277) white prepupae new  (398) white prepupae 12hr  (305) white prepupae 24hr  (165) pupae 2d postWPP  (176) pupae 3d postWPP  121 pupae 4d postWPP  129 adult male 01day  (151) adult male 05day  119 adult male 30day    95 adult female 01day  121 adult female 05day    79 adult female 30day    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    374 embryo 06-08hr    383 embryo 08-10hr    306 embryo 10-12hr    203 embryo 12-14hr    255 embryo 14-16hr    220 embryo 16-18hr    232 embryo 18-20hr    189 embryo 20-22hr    142 embryo 22-24hr    164 larva L1    95 larva L2    102 larva L3 12hr old    105 larva L3 puffstage 1-2    103 larva L3 puffstage 3-6    167 larva L3 puffstage 7-9    277 white prepupae new    398 white prepupae 12hr    305 white prepupae 24hr    165 pupae 2d postWPP    176 pupae 3d postWPP    121 pupae 4d postWPP    129 adult male 01day    151 adult male 05day    119 adult male 30day    95 adult female 01day    121 adult female 05day    79 adult female 30day    69 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    312 Schneider line 2 Sg4    71 embryonic 1182-4H    204 embryonic GM2    65 embryonic Kc167    84 embryonic S1    764 embryonic S3    484 leg disc CME L1    125 wing disc CME-W2    161 wing disc ML-DmD8    278 wing disc ML-DmD9    249 wing disc ML-DmD16-c3    164 wing disc ML-DmD21    71 wing disc ML-DmD32    142 haltere disc ML-DmD17-c3    183 eye-antennal disc ML-DmD11    118 antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1    283 CNS ML-DmBG1-c1    851 CNS ML-DmBG2-c2    788 tumorous blood cells mbn2    356 ovary fGS/OSS    962 ovary OSC    464 ovary OSS    395 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (312) Schneider line 2 Sg4  (71) embryonic 1182-4H  (204) embryonic GM2  (65) embryonic Kc167  (84) embryonic S1  (764) embryonic S3  (484) leg disc CME L1  (125) wing disc CME-W2  (161) wing disc ML-DmD8  (278) wing disc ML-DmD9  (249) wing disc ML-DmD16-c3  (164) wing disc ML-DmD21  (71) wing disc ML-DmD32  (142) haltere disc ML-DmD17-c3  (183) eye-antennal disc ML-DmD11  (118) antennal disc ML-DmD20-c5  (68) mixed discs ML-DmD4-c1  (283) CNS ML-DmBG1-c1  (851) CNS ML-DmBG2-c2  (788) tumorous blood cells mbn2  (356) ovary fGS/OSS  (962) ovary OSC  (464) ovary OSS  (395) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (312) Schneider line 2 Sg4    71 embryonic 1182-4H  (204) embryonic GM2    65 embryonic Kc167    84 embryonic S1  (764) embryonic S3  (484) leg disc CME L1  (125) wing disc CME-W2  (161) wing disc ML-DmD8  (278) wing disc ML-DmD9  (249) wing disc ML-DmD16-c3  (164) wing disc ML-DmD21    71 wing disc ML-DmD32  (142) haltere disc ML-DmD17-c3  (183) eye-antennal disc ML-DmD11  (118) antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1  (283) CNS ML-DmBG1-c1  (851) CNS ML-DmBG2-c2  (788) tumorous blood cells mbn2  (356) ovary fGS/OSS  (962) ovary OSC  (464) ovary OSS  (395) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    312 Schneider line 2 Sg4    71 embryonic 1182-4H    204 embryonic GM2    65 embryonic Kc167    84 embryonic S1    764 embryonic S3    484 leg disc CME L1    125 wing disc CME-W2    161 wing disc ML-DmD8    278 wing disc ML-DmD9    249 wing disc ML-DmD16-c3    164 wing disc ML-DmD21    71 wing disc ML-DmD32    142 haltere disc ML-DmD17-c3    183 eye-antennal disc ML-DmD11    118 antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1    283 CNS ML-DmBG1-c1    851 CNS ML-DmBG2-c2    788 tumorous blood cells mbn2    356 ovary fGS/OSS    962 ovary OSC    464 ovary OSS    395 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    312 Schneider line 2 Sg4    71 embryonic 1182-4H    204 embryonic GM2    65 embryonic Kc167    84 embryonic S1    764 embryonic S3    484 leg disc CME L1    125 wing disc CME-W2    161 wing disc ML-DmD8    278 wing disc ML-DmD9    249 wing disc ML-DmD16-c3    164 wing disc ML-DmD21    71 wing disc ML-DmD32    142 haltere disc ML-DmD17-c3    183 eye-antennal disc ML-DmD11    118 antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1    283 CNS ML-DmBG1-c1    851 CNS ML-DmBG2-c2    788 tumorous blood cells mbn2    356 ovary fGS/OSS    962 ovary OSC    464 ovary OSS    395 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (312) Schneider line 2 Sg4  (71) embryonic 1182-4H  (204) embryonic GM2  (65) embryonic Kc167  (84) embryonic S1  (764) embryonic S3  (484) leg disc CME L1  (125) wing disc CME-W2  (161) wing disc ML-DmD8  (278) wing disc ML-DmD9  (249) wing disc ML-DmD16-c3  (164) wing disc ML-DmD21  (71) wing disc ML-DmD32  (142) haltere disc ML-DmD17-c3  (183) eye-antennal disc ML-DmD11  (118) antennal disc ML-DmD20-c5  (68) mixed discs ML-DmD4-c1  (283) CNS ML-DmBG1-c1  (851) CNS ML-DmBG2-c2  (788) tumorous blood cells mbn2  (356) ovary fGS/OSS  (962) ovary OSC  (464) ovary OSS  (395) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (312) Schneider line 2 Sg4    71 embryonic 1182-4H  (204) embryonic GM2    65 embryonic Kc167    84 embryonic S1  (764) embryonic S3  (484) leg disc CME L1  125 wing disc CME-W2  (161) wing disc ML-DmD8  (278) wing disc ML-DmD9  (249) wing disc ML-DmD16-c3  (164) wing disc ML-DmD21    71 wing disc ML-DmD32  142 haltere disc ML-DmD17-c3  (183) eye-antennal disc ML-DmD11  118 antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1  (283) CNS ML-DmBG1-c1  (851) CNS ML-DmBG2-c2  (788) tumorous blood cells mbn2  (356) ovary fGS/OSS  (962) ovary OSC  (464) ovary OSS  (395) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    312 Schneider line 2 Sg4    71 embryonic 1182-4H    204 embryonic GM2    65 embryonic Kc167    84 embryonic S1    764 embryonic S3    484 leg disc CME L1    125 wing disc CME-W2    161 wing disc ML-DmD8    278 wing disc ML-DmD9    249 wing disc ML-DmD16-c3    164 wing disc ML-DmD21    71 wing disc ML-DmD32    142 haltere disc ML-DmD17-c3    183 eye-antennal disc ML-DmD11    118 antennal disc ML-DmD20-c5    68 mixed discs ML-DmD4-c1    283 CNS ML-DmBG1-c1    851 CNS ML-DmBG2-c2    788 tumorous blood cells mbn2    356 ovary fGS/OSS    962 ovary OSC    464 ovary OSS    395 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    305 cold shock, 4-day adult    298 heat shock, 4-day adult    118 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    204 Cadmium 50 mM 48 hrs, 4-day adult    152 Cadmium 100 mM 48 hrs, 4-day adult    115 Copper 0.5 mM 12 hrs, larvae L3    253 Copper 15 mM 48 hrs, 4-day adult    217 Zinc 5 mM 12 hrs, larvae L3    246 Zinc 4.5 mM 48 hrs, 4-day adult    328 Ethanol 2.5% 3 hrs, larvae L3    103 Ethanol 5% 3 hrs, larvae L3    171 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    188 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    152 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    178 Paraquat 10 mM 48 hrs, 4-day adult    205 Rotenone 2 μg 12 hrs, larvae L3    152 Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (305) cold shock, 4-day adult  (298) heat shock, 4-day adult  (118) Cadmium 50 mM 6 hrs, larvae L3  (103) Cadmium 50 mM 12 hrs, larvae L3  (204) Cadmium 50 mM 48 hrs, 4-day adult  (152) Cadmium 100 mM 48 hrs, 4-day adult  (115) Copper 0.5 mM 12 hrs, larvae L3  (253) Copper 15 mM 48 hrs, 4-day adult  (217) Zinc 5 mM 12 hrs, larvae L3  (246) Zinc 4.5 mM 48 hrs, 4-day adult  (328) Ethanol 2.5% 3 hrs, larvae L3  (103) Ethanol 5% 3 hrs, larvae L3  (171) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (188) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (152) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (178) Paraquat 10 mM 48 hrs, 4-day adult  (205) Rotenone 2 μg 12 hrs, larvae L3  (152) Rotenone 8 μg 12 hrs, larvae L3  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (305) cold shock, 4-day adult  (298) heat shock, 4-day adult  (118) Cadmium 50 mM 6 hrs, larvae L3  103 Cadmium 50 mM 12 hrs, larvae L3  (204) Cadmium 50 mM 48 hrs, 4-day adult  (152) Cadmium 100 mM 48 hrs, 4-day adult  (115) Copper 0.5 mM 12 hrs, larvae L3  (253) Copper 15 mM 48 hrs, 4-day adult  (217) Zinc 5 mM 12 hrs, larvae L3  (246) Zinc 4.5 mM 48 hrs, 4-day adult  (328) Ethanol 2.5% 3 hrs, larvae L3  103 Ethanol 5% 3 hrs, larvae L3  (171) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (188) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (152) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (178) Paraquat 10 mM 48 hrs, 4-day adult  (205) Rotenone 2 μg 12 hrs, larvae L3  (152) Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    305 cold shock, 4-day adult    298 heat shock, 4-day adult    118 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    204 Cadmium 50 mM 48 hrs, 4-day adult    152 Cadmium 100 mM 48 hrs, 4-day adult    115 Copper 0.5 mM 12 hrs, larvae L3    253 Copper 15 mM 48 hrs, 4-day adult    217 Zinc 5 mM 12 hrs, larvae L3    246 Zinc 4.5 mM 48 hrs, 4-day adult    328 Ethanol 2.5% 3 hrs, larvae L3    103 Ethanol 5% 3 hrs, larvae L3    171 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    188 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    152 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    178 Paraquat 10 mM 48 hrs, 4-day adult    205 Rotenone 2 μg 12 hrs, larvae L3    152 Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    305 cold shock, 4-day adult    298 heat shock, 4-day adult    118 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    204 Cadmium 50 mM 48 hrs, 4-day adult    152 Cadmium 100 mM 48 hrs, 4-day adult    115 Copper 0.5 mM 12 hrs, larvae L3    253 Copper 15 mM 48 hrs, 4-day adult    217 Zinc 5 mM 12 hrs, larvae L3    246 Zinc 4.5 mM 48 hrs, 4-day adult    328 Ethanol 2.5% 3 hrs, larvae L3    103 Ethanol 5% 3 hrs, larvae L3    171 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    188 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    152 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    178 Paraquat 10 mM 48 hrs, 4-day adult    205 Rotenone 2 μg 12 hrs, larvae L3    152 Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (305) cold shock, 4-day adult  (298) heat shock, 4-day adult  (118) Cadmium 50 mM 6 hrs, larvae L3  (103) Cadmium 50 mM 12 hrs, larvae L3  (204) Cadmium 50 mM 48 hrs, 4-day adult  (152) Cadmium 100 mM 48 hrs, 4-day adult  (115) Copper 0.5 mM 12 hrs, larvae L3  (253) Copper 15 mM 48 hrs, 4-day adult  (217) Zinc 5 mM 12 hrs, larvae L3  (246) Zinc 4.5 mM 48 hrs, 4-day adult  (328) Ethanol 2.5% 3 hrs, larvae L3  (103) Ethanol 5% 3 hrs, larvae L3  (171) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (188) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (152) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (178) Paraquat 10 mM 48 hrs, 4-day adult  (205) Rotenone 2 μg 12 hrs, larvae L3  (152) Rotenone 8 μg 12 hrs, larvae L3  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (305) cold shock, 4-day adult  (298) heat shock, 4-day adult  118 Cadmium 50 mM 6 hrs, larvae L3  103 Cadmium 50 mM 12 hrs, larvae L3  (204) Cadmium 50 mM 48 hrs, 4-day adult  (152) Cadmium 100 mM 48 hrs, 4-day adult  115 Copper 0.5 mM 12 hrs, larvae L3  (253) Copper 15 mM 48 hrs, 4-day adult  (217) Zinc 5 mM 12 hrs, larvae L3  (246) Zinc 4.5 mM 48 hrs, 4-day adult  (328) Ethanol 2.5% 3 hrs, larvae L3  103 Ethanol 5% 3 hrs, larvae L3  (171) Ethanol 10% 3 hrs, larvae L3  134 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (188) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (152) Caffeine 25 mg/ml 48 hrs, 4-day adult  (241) Paraquat 5 mM 48 hrs, 4-day adult  (178) Paraquat 10 mM 48 hrs, 4-day adult  (205) Rotenone 2 μg 12 hrs, larvae L3  (152) Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    305 cold shock, 4-day adult    298 heat shock, 4-day adult    118 Cadmium 50 mM 6 hrs, larvae L3    103 Cadmium 50 mM 12 hrs, larvae L3    204 Cadmium 50 mM 48 hrs, 4-day adult    152 Cadmium 100 mM 48 hrs, 4-day adult    115 Copper 0.5 mM 12 hrs, larvae L3    253 Copper 15 mM 48 hrs, 4-day adult    217 Zinc 5 mM 12 hrs, larvae L3    246 Zinc 4.5 mM 48 hrs, 4-day adult    328 Ethanol 2.5% 3 hrs, larvae L3    103 Ethanol 5% 3 hrs, larvae L3    171 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    188 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    152 Caffeine 25 mg/ml 48 hrs, 4-day adult    241 Paraquat 5 mM 48 hrs, 4-day adult    178 Paraquat 10 mM 48 hrs, 4-day adult    205 Rotenone 2 μg 12 hrs, larvae L3    152 Rotenone 8 μg 12 hrs, larvae L3    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_11 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • RE46351 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013272 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5820-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Gp150 Stages(s) 4-6 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal (with Df(2R)02311) Gp15052A lethal (with Gp1503) Gp150k11120b lethal (with Gp150k11120b) Gp1503 lethal | pupal stage, with Scer\GAL4pnr-MD237 Gp150GD10 Gp150GD2506 lethal | recessive Gp15052A partially lethal - majority die Gp1502 Gp1503 partially lethal - majority die (with Gp1502) Gp15052A partially lethal - majority die (with Gp1503) Gp15052A partially lethal - majority die (with Gp15052A) Gp1502 Gp1503 partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Gp150GD2506 Gp150GD14413 Sterility Allele female sterile Gp150unspecified female sterile (with Gp1502) Gp15052A female sterile (with Gp1503) Gp15052A female sterile (with Gp15052A) Gp1502 Gp1503 male semi-sterile Gp150unspecified Other Phenotypes Allele behavior defective | recessive Gp150BG01043 body color defective, with Scer\GAL4pnr-MD237 Gp150GD14413 visible Gp1503 Gp1504 Gp150k11107b Gp150k11120b visible, with Scer\GAL4pnr-MD237 Gp150GD2506 Gp150GD14413 visible | recessive Gp150unspecified Phenotype manifest in Allele anterior scutellar bristle (with Gp1503) Gp150k11120b anterior scutellar bristle (with Gp150k11120b) Gp1503 chaeta | supernumerary, with Scer\GAL4pnr-MD237 Gp150GD14413 eye Gp1503 Gp1504 Gp150k11107b Gp150k11120b Gp150unspecified eye (with Df(2R)02311) Gp1503 eye (with Gp1503) Gp1504 Gp150k11120b eye (with Gp1504) Gp1503 eye (with Gp150k11120b) Gp1503 eye photoreceptor cell (with Gp1503) Gp1504 eye photoreceptor cell (with Gp1504) Gp1503 eye photoreceptor cell | somatic clone Gp1503 eye photoreceptor cell | somatic clone (with Gp150k11107b) Gp150k11120b eye photoreceptor cell | somatic clone (with Gp150k11120b) Gp150k11107b macrochaeta (with Df(2R)Liprin-γH1) Gp150k11120b mesothoracic tergum, with Scer\GAL4pnr-MD237 Gp150GD2506 Gp150GD14413 mesothoracic tergum & microchaeta Gp150k11107b ocellar bristle Gp150k11107b ommatidium Gp1503 Gp150k11120b Gp150unspecified ommatidium (with Df(2R)02311) Gp1503 ommatidium (with Gp1503) Gp1504 Gp150k11120b ommatidium (with Gp1504) Gp1503 ommatidium (with Gp150k11120b) Gp1503 Gp150P8 ommatidium (with Gp150P8) Gp150k11120b ommatidium | somatic clone Gp1503 ommatidium | somatic clone (with Gp150k11107b) Gp150k11120b ommatidium | somatic clone (with Gp150k11120b) Gp150k11107b photoreceptor cell R1 (with Gp1503) Gp150k11120b photoreceptor cell R1 (with Gp150k11120b) Gp1503 photoreceptor cell R6 (with Gp1503) Gp150k11120b photoreceptor cell R6 (with Gp150k11120b) Gp1503 photoreceptor cell R8 (with Gp1503) Gp150k11120b photoreceptor cell R8 (with Gp150k11120b) Gp1503 photoreceptor cell R8 | cell autonomous | somatic clone Gp150k11120b trichogen cell, with Scer\GAL4pnr-MD237 Gp150GD14413 wing margin, with Scer\GAL4dpp.blk1 Gp150Scer\UAS.cLa wing margin bristle Gp1503 Gp1504 Gp150k11107b Gp150k11120b wing margin bristle | ectopic Gp1503 Gp1504 Gp150k11107b Gp150k11120b wing vein L3 | ectopic Gp1503 Gp1504 Gp150k11107b Gp150k11120b
Classical Alleles ( 19 )
For All Classical Alleles Show
Allele of Gp150 Class Mutagen Stocks Known lesion Gp150k11120b 2 -- Gp150BG01043 1 -- Gp150MI01725 1 -- Gp150NP4285 1 -- Gp1503 loss of function allele, amorphic allele - genetic evidence ethyl methanesulfonate 0 -- Gp1502 loss of function allele 0 -- Gp1504 ethyl methanesulfonate 0 Yes Gp15052A P-element activity 0 Yes Gp150k11107b 0 Yes Gp150P10 P-element activity 0 -- Gp150P11 P-element activity 0 -- Gp150P12 P-element activity 0 -- Gp150P13 P-element activity 0 -- Gp150P15 P-element activity 0 -- Gp150P16 P-element activity 0 -- Gp150P2 P-element activity 0 -- Gp150P6 P-element activity 0 -- Gp150P8 P-element activity 0 Yes Gp150unspecified 0 --
Alleles Carried on Transgenic Constructs ( 12 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Gp150 Class Mutagen Stocks Known lesion Gp150GD10 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Gp150GD14413 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gp150GD2506 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gp150HMS00395 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gp150KK104931 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Gp150+t17.5 in vitro construct - genomic fragment 0 Yes Gp150GMR.PF in vitro construct - regulatory fusion 0 Yes Gp150MtnA.6x.T:Hsap\MYC in vitro construct - regulatory fusion 0 Yes Gp150MtnA.PF in vitro construct - regulatory fusion 0 Yes Gp150NIG.5820R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Gp150Scer\UAS.cLa in vitro construct - regulatory fusion 0 Yes Gp150ΔECD.GMR in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)02311 (Fetchko et al., 2002, Melnattur et al., 2002) Df(2R)Liprin-γH1 (Astigarraga et al., 2010) Df(2R)X58-7 (Melnattur et al., 2002) Df(2R)X58-8 (Melnattur et al., 2002) Df(2R)X58-12 (Melnattur et al., 2002)
Partially disrupted in	Df(2R)Liprin-γH1 (Astigarraga et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10} NA P{GD2506} NA P{GD14413} NA P{KK104931} NA P{NIG.5820R} NA P{TRiP.HMS00395} NA P{UAS-Gp150.L} NA characterization construct P{GMR-Gp150.F} NA P{GMR-Gp150.ΔECD} NA P{Gp150+t17.5} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system P{GawB}Gp15052A No P{GawB}Gp150NP4285 No miscellaneous insertions Mi{MIC}Gp150MI01725 NA P{GT1}Gp150BG01043 NA insertion of enhancer trap P{lacW}Gp150P2 No P{lacW}Gp150P6 No P{lacW}Gp150P8 No P{lacW}Gp150P10 No P{lacW}Gp150P11 No P{lacW}Gp150P12 No P{lacW}Gp150P13 No P{lacW}Gp150P15 No P{lacW}Gp150P16 No insertion of mobile activating element P{GSV1}EP-296 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
compound eye development inferred from mutant phenotype (Fetchko et al., 2002) inter-male aggressive behavior inferred from mutant phenotype (Edwards et al., 2009) transmembrane receptor protein tyrosine phosphatase signaling pathway inferred from direct assay (Tian and Zinn, 1994)
Cellular Component
CV term Evidence References
plasma membrane inferred from direct assay (Tian and Zinn, 1994)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Gp150 - CG11911 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Gp150 - CG5027 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Gp150 - nemy anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Gp150 allele Gene References Gp1503 sca (Li et al., 2003) Gp1504 sca (Li et al., 2003) Gp150k11120b Dl (Fetchko et al., 2002) N (Fetchko et al., 2002) Gp150P8 Dl (Fetchko et al., 2002) N (Fetchko et al., 2002) Gp150Scer\UAS.cLa sca (Li et al., 2003)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63166 DroID - A comprehensive database of gene and protein interactions. • FBgn0013272 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37549
Orthologs
OrthoDB Orthologs (27) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6B5PQJ Dipteran inclusive ortholog search EOG6DJK4H Insect inclusive ortholog search EOG6H716J Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6B5PQJ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Gp150     Drosophila simulans   Dsim\GD11658 Y   Drosophila sechellia   Dsec\GM15899 Y   Drosophila erecta   Dere\GG22178 Y   Drosophila yakuba   Dyak\GE14172 Y   Drosophila ananassae   Dana\GF11881 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA19154 Y   Drosophila persimilis   Dper\GL17534 Y   Drosophila willistoni   Dwil\GK20809 Y   Drosophila virilis   Dvir\Gp150 Y   Drosophila mojavensis   Dmoj\GI20549 Y   Drosophila grimshawi   Dgri\GH21800 Y
Orthologs in non-Drosophila Dipterans (EOG6DJK4H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003720   Anopheles gambiae Malaria mosquito  Agam\AGAP006645   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005431
Orthologs in non-Dipteran Insects (EOG6H716J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50897   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007622   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH16785   Atta cephalotes Leafcutter ant  Acep\ACEP17084   Camponotus floridanus Florida carpenter ant  Cflo\CFLO18808   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18462   Linepithema humile Argentine ant  Lhum\LH12933   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21137   Solenopsis invicta Red fire ant  Sinv\SINV11400   Bombyx mori Silkmoth  Bmor\BGIBMGA002618   Pediculus humanus Human body louse  Phum\PHUM617290   Tribolium castaneum Red flour beetle  Tcas\TC001743
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11658 Drosophila sechellia Dsec\GM15899 Drosophila erecta Dere\GG22178 Drosophila yakuba Dyak\GE14172 Drosophila ananassae Dana\GF11881 Drosophila pseudoobscura pseudoobscura Dpse\GA19154 Drosophila persimilis Dper\GL17534 Drosophila willistoni Dwil\GK20809 Drosophila virilis Dvir\Gp150 Drosophila mojavensis Dmoj\GI20549 Drosophila grimshawi Dgri\GH21800
Stocks & Reagents
Stocks Listed in FlyBase ( 11 )
Bloomington	12840 w1118; P{GT1}Gp150BG01043 34241 y1 w*; Mi{MIC}Gp150MI01725/SM6a 32400 y1 sc* v1; P{TRiP.HMS00395}attP2 11015 y1 w67c23; P{lacW}l(2)k11120ak11120a Gp150k11120b/CyO
Kyoto	104656 y* w*; P{GawB}Gp150NP4285 / CyO, P{UAS-lacZ.UW14}UW14 111299 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}42D P{lacW}l(2)k11120ak11120a Gp150k11120b /CyO y+
VDRC	v100134 P{KK104931}VIE-260B v899 w1118; P{GD10}v899 v900 w1118; P{GD10}v900 v33294 w1118 P{GD2506}v33294 v36301 w1118 P{GD14413}v36301
Genomic Clones ( 2 )
	BACR02I11 BACR48M13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 575 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE46351 RE72245
Other clones	RT10449
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03469 GH08023 GH10621 GH18240 GH23251 GH25825 GH26901 GM01913 GM03061 GM06443 GM10768 GM18264 GM19679 LD41138 LP01539 LP06088 LP09814 LP11060 LP18081 LP19228 LP23016 LP23064 LP23379 RE07828 RE10189 RE11166 RE15316 RE16049 RE17549 RE17719 RE20468 RE22021 RE24960 RE25252 RE26312 RE27350 RE28054 RE29358 RE29751 RE30831 RE31269 RE31682 RE32237 RE32679 RE35609 RE35722 RE35815 RE37274 RE37340 RE38991 RE39169 RE42307 RE43737 RE43881 RE44056 RE44113 RE45076 RE46008 RE46144 RE48087 RE52040 RE52782 RE54643 RE56407 RE56651 RE57876 RE58459 RE59523 RE61662 RE64402 RE65406 RE67279 RE67694 RE67853 RE70319 RE70547 RE73927 RE74711 SD01978 SD02926 SD05784 SD06596 SD12622 SD15076 SD16295
Other clones	1735 2090 4874 28387 30510 34722 35303 36479 38606 42090 53382 56827 58881 59971 64991 66111 70935 71371 72798 84203 100772 106602 107649 108131 144495 146930 148703 163396 165666 178610 182327 214245.43 277041 280700 571422 AA433234 CK01.11A.B2 CK01.44C.C1 CK01.94C.D2 CK01.96B.E3 CK01.105A.G11 CK01.112C.G3 CK01.128A.C7 CK01.129B.D9 CK01.129D.E9 CK01900 EC14254 EC40914 EK001726 EK050912 EK073645 EK087828 EK095813 EK096217 EK098212 EK123219 EK123458 EK123728 EK136440 EK144556 EK147314 EK155237 EK174160 EK191759 EK193928 EK202302 EK217928 EK223260 EK232118 EK234718 EK249636 EK250245 EK257002 EK267920 EK286921 EK304164 EK305628 EN16839 EP14932 ESG0116b.B21_H09 FGA006G01 FGB002B08 FGM003A09 FGM104B11 FGM303H01 FGM310C06 FGM321F01 FGM324G09 RE43853 RE55874 RP003001199 RP003006249 RP003007500 RP003011809 RP003018324 RP003019334 RP003021823 RP003023153 RP003024897 RP003029884 RP003033413 RP003033985 RP003035188 RP003037469 RP003038457 RP003042687 RP003044406 RP003047393 RP003049864 RP003050344 RP003050364 RP003052485 RP003052719 RP003055717 RP003056887 RP003060540 RP003061165 RP003066152 RP003067711 RP003069973 RP003070970 RP003075190 RP003075929 RP003077172 RP003078315 RP003078503 RP003078983 RP003079736 RP003081949 RP003082414 RP003086578 RP003087087 RP003090228 RP003090451 RP003090676 RP003094233 RP003100961 RP003101033 RP003102096 RP003105162 RP003106309 RP003106855 RP003107926 RP003108838 RP003108991 RP003109397 RP003109993 RP003111552 RP003111622 RP003113126 RP003115796 RP003116036 RP003116462 RP003123761 RP003126648 RP003127114 RP003129260 RP003129435 RP003132928 RP003133341 RP003135213 RP003137855 RP003139260 RP003140702 RP003142271 RP003142345 RP003142681 RP003143061 RP003144766 RP003147184 RP003150996 RP003151253 RP003151810 RP003153216 RP003153481 RP003154692 RP003155487 RP003158804 RP003158843 RP003160967 RP003163013 RP003165141 RP003167424 RP003169444 RP003172636 RP003172707 RP003174422 RP003176083 RP003176973 RP003181444 RP003183141 RP003185929 RP003186767 RP003188825 RP003192227 RP003193560 RP003195968 RP003196936 RP003198142 RP003198939 RP003201864 RP003202808 RP003204798 RP003205514 RP003205704 RP003206081 RP003206930 RP003210345 RP003210744 RP003211250 RP003211790 RP003212360 RP003212417 RP003213293 RP003213590 RP003216227 RP003216879 RP003217689 RP003218319 RP003218538 RP003219268 RP003219791 RP003220270 RP003220366 RP003222742 RP003223644 RP003224637 RP003228854 RP003232204 RP003232982 RP003233653 RP003234016 RP003234908 RP003239479 RP003240221 RP003241241 RP003243367 RP003244057 RP003244274 RP003246103 RP003247040 RP003248462 RP003251236 RP003252284 RP003253354 RP003253585 RP003256083 RP003257015 RP003257332 RP003257722 RP003258325 RP003258342 RP003259214 RP003259987 RP003260911 RP003263519 RP003263823 RP003265220 RP003265707 RP003267306 RP003270821 RP003271678 RP003272937 RP003273617 RP003274453 RP003275204 RP003277353 RP003279562 RP003280284 RP003280550 RP003281886 RP003282024 RP003284599 RP003287008 RP003288091 RP003289049 RP003289074 RP003289986 RP003290204 RP003290874 RP003292988 RP003298503 RP003301115 RP003301848 RP003302346 RP003304968 RP003305652 RP003307140 RP003307927 RP003310636 RP003311820 RP003311911 RP003313421 RP003313706 RP003315666 RP003315915 RP003316930 RP003317146 RP003319770 RP003320466 RP003320600 RP003322600 RP003325536 RP003326552 RP003327675 RP003328915 RP003329701 RP003330540 RP003332458 RP003334424 RP003335713 RP003337856 RP003338796 RP003339892 RP003340319 RP003341780 RP003347244 RP003350651 RP003352294 RP003353025 RP003354267 RP003354474 RP003356337 RP003356670 RP003357855 RP003358591 RP003358633 RP003360109 RP003369397 RP003372009 RP003373122 RP003373158 RP003373967 RP003385809 RP003387920 RP003395263 RP003399316 RP003408625 RP003411933 RP003413728 RP003414500 RP003415180 RP003415932 RP003417248 RP003421046 RP003425159 RP003429365 RP003431419 RP003437394 RP003438700 RP003448071 RP003448620 RP003451382 RP003453720 RP003453817 RP003454861 RP003455508 RP003456409 RP003466578 RP003467120 RP003470605 RP003471041 RP003473745 RP003475091 RP003476383 RP003476649 RP003477190 RP003486219 RP003490679 RP003490801 RP003491014 RP003494108 RP003494419 RP003494998 RP003495771 RP003496188 RP003502756 RP003505235 RP003505655 RP003512355 RP003513490 RP003514127 RP003514473 RP003514516 RP003514565 RP003517127 RP003517309 RP003521283 RP003524152 RP003525126 RP003525840 RP003526082 RP003526254 RP003528526 RP003528875 RP003529184 RP003531816 RP003531853 RP003533265 RP003536961 RP003538994 RP003541926 RP003542787 RP003545488 RP003547810 RP003548172 RP003549464 RP003550193 RP003553832 RP003560375 RP003560827 RP003561196 RP003561226 RP003561286 RP003562545 RP003573341 RP003575503 RP003575766 RP003578958 RP003579935 RP003581402 RP003581733 RP003584194 RP003585106 RP003585588 RP003585838 RP003589329 RP003590616 RP003590881 RP003594046 RP003594914 RP003595200 RP003596733 RP003601036 RP003602092 RP003602589 RP003603821 RP003605009 RP003608976 RP003609900 RP003610525 RP003611742 RP003611871 RP003612078 RP003615132 RP003615888 RP003616140 RP003621541 RP003621577 RP003621973 RP003622348 RP003624794 RP003629123 RP003629300 RP003629450 RP003629790 RP003631216 RP003632255 RP003632471 RP003635739 RP003635934 RP003638932 RP003642658 RP003643040 RP003644779 RP003648737 RP003655540 RP003656449 RP003658165 RP003659293 RP003661656 RP003661961 RP003663146 RP003663405 RP003663704 RP003666637 RP003666805 RP003666878 RP003667936 RP003668195 RP003669572 RP003670704 RP003672453 RP003672567 RP003674654 RP003676228 RP003676340
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0013272 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37549
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Gp150 CG5820 (Milshina, 1999.11)
Source for database merge of	Source for merge of: Gp150 anon-EST:fe2A1 (Bayraktaroglu, 2000.11.2) Source for merge of: Gp150 l(2)52A (Melnattur et al., 2002)
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Endosomal sca and Gp150 may promote N activation in response to Dl, by regulating acquisition of insensitivity to Dl in a subset of cells. (Li et al., 2003) Gp150 is required for early ommatidial development and may function in intracellular vesicles to modulate Dl-N signalling for cell fate control and tissue morphogenesis. (Fetchko et al., 2002) Ptp10D and Gp150 form stable complexes in culture cells and in wild type larval tissue. Ptp10D cytoplasmic domain is sufficient to confer binding to Gp150. Results support the hypothesis that Ptp10D regulates Gp150 signaling in vivo. (Fashena and Zinn, 1997) Transmembrane Gp150 glycoprotein selectively interacts with the active site of the catalytic domain of Ptp10D (interaction is blocked by mutation of the active site or by the inhibitor vanadate). Ptp10D may function in vivo to regulate phosphorylation of Gp150 thereby controlling interactions with downstream effectors. (Tian and Zinn, 1994)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057701 NM_166527 NM_166528 NM_166529 RefSeq (Proteins) • NP_477049 NP_726190 NP_726191 NP_726192 DDBJ / EMBL / GenBank • AA433234 AAA61796 AAB71081 AAF46831 AAG22195 AAK39644 AAM68221 AAM68222 AAT94424 AC005714 AY029705 BI361930 BI578379 BT015195 U15220 U66411 Z50242 Entrez Gene - A searchable database of RefSeq genes. • 37549 UniProtKB/TrEMBL • Q6AWQ3 Q7JNM8 Q8MLT4 Q95PA9 Q24007
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Leucine-rich repeat (IPR001611) Leucine-rich repeat, typical subtype (IPR003591) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE46351
Linkouts
	BioGRID - A database of protein and genetic interactions • 63166 DroID - A comprehensive database of gene and protein interactions. • FBgn0013272 DRSC - Results from RNAi screens. • FBgn0013272 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013272 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5820-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0013272 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37549 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37549 modMine - Data generated by the modENCODE project. • FBgn0013272
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	anon-EST:fe2A1   CG5820 (Molnar et al., 2006, Keleman et al., 2009.8.5, Ni et al., 2010.12.1, Yano et al., 2012) CT18251 (Hynes and Zhao, 2000) gp150 (Wilkin et al., 2004, Jasper et al., 2001, Lindgren et al., 2003, Melnattur et al., 2002, Hynes and Zhao, 2000, Dhulkotia et al., 2000, Zinn, 1994.9.28, Lai et al., 1999, Lai et al., 1999, Martin-Bermudo et al., 1998, Van Vactor et al., 1998, Fashena and Zinn, 1997, Nakamura et al., 1996, Desai et al., 1995, Tian and Zinn, 1994, Li et al., 2003, Akbar et al., 2007, Lindgren et al., 2007, Hanyu-Nakamura et al., 2008, Akbar et al., 2009) GP150 (Nakahara and Carthew, 2004) Gp150 (Molnar et al., 2006, Lecuyer et al., 2007, Edwards et al., 2009, Weake et al., 2009, Wheeler et al., 2009, Astigarraga et al., 2010, Egger et al., 2010, Rehwinkel et al., 2004, Abruzzi et al., 2011, Yano et al., 2012, Japanese National Institute of Genetics, 2012.5.21) l(2)52A   p150   unnamed (Nakamura, 1996.8.8, Schmid and Tautz, 1997, Zhou et al., 1997)
Name Synonym	anon-fast-evolving-2A1   glycoprotein 150 (Tian and Zinn, 1994) Gp150
Secondary FlyBase IDs
	FBgn0022992 FBgn0025238 FBgn0027193
References ( 64 )
Generate a list of	All references relating to this gene ( 64 )
List References by type	Research paper  ( 27 ) Supplementary material  ( 6 ) Review  ( 2 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 10 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) Website  ( 1 )
Recent research papers ( 4 )
	Yano et al., 2012, J. Neurogenet. 26(1): 53--63 Identification of proteasome components required for apical localization of chaoptin using functional genomics. [FBrf0217843] Abruzzi et al., 2011, Genes Dev. 25(22): 2374--2386 Drosophila CLOCK target gene characterization: implications for circadian tissue-specific gene expression. [FBrf0216798] Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Zwarts et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(41): 17070--17075 Complex genetic architecture of Drosophila aggressive behavior. [FBrf0216413] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...