A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Dmel\MT:DNA

General Information
SymbolDmel\MT:DNASpeciesD. melanogaster
NameMitochondrial DNAAnnotation symbol
Feature typemitochondrial_sequenceFlyBase IDFBgn0013298
Gene Model StatusUnannotated Stock availability None publicly available
Also Known AsmtDNA
Genomic Location
Chromosome (arm)Recombination map
Cytogenetic mapSequence location
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Automatically generated summary

See sections below for more information
The gene Mitochondrial DNA is referred to in FlyBase by the symbol Dmel\MT:DNA (FBgn0013298). It is a mitochondrial_sequence from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has no annotated transcripts. Gene has not been localized to the genome sequence.
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FB2013_03
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FlyBase Computed Cytological Location
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Experimentally Determined Cytological Location
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Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
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Annotated Transcripts
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Annotated Polypeptides
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DDBJ /
EMBL /
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DNA sequence
Protein sequence
Name
M26820
 
X05160
 
X05162
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
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Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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Phenotype manifest in
Allele
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Allele of MT:DNAClassMutagenStocksKnown lesion
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Allele of MT:DNAClassMutagenStocksKnown lesion
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Transgenic Constructs
Type of construct
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Type of insertions
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hide Sequence Ontology: Class of Gene
mitochondrial_sequence
 
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Interacts with
Please look at the allele data for full details of the genetic interactions
MT:DNA allele
Gene
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hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
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Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
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Source for database identity of
Source for database merge of
Source for merge of: mt:DNA snRNA-d
(Mount, 2000.5.30)
Additional comments
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This is 90% identical to a piece of the mitochondrial genome <up>S. Mount</up>.
(Mount, 2000.5.30)
Temperature-dependent selection in mtDNA transmission is co-operatively regulated by gene products that are encoded by the X, second and third chromosomes.
(Doi et al., 1999)
The 4.6kb A+T rich region of D.melanogaster MT:DNA has been cloned and sequenced.
(Lewis et al., 1994)
The level of MT:DNA remains fairly constant throughout the life span of D.melanogaster, being approximately 1% of the total DNA at all ages.
(Calleja et al., 1993)
MT:DNA transmission in the heteroplasmic state is selective and temperature-dependent.
(Matsuura et al., 1993)
Transmission of two types of MT:DNA are examined at 19oC and 25oC using heteroplasmic lines. Results demonstrate selective transmission of one type of MT:DNA depends on the temperature at which the heteroplasmic lines are maintained.
(Matsuura et al., 1991)
The temperature-dependency of total electron-transport activity of mitochondria encoded by both MT:DNA and Dmau\MT:DNA does not differ from that of mitochondria encoded by MT:DNA alone. For the selective transmission of mitochondrial DNA in the heteroplasmic state the temperature-dependency of the mitochondrial respiratory function does not appear to play a major role as a selective force.
(Nagata and Matsuura, 1991)
Temperature-dependent transmission of mitochondrial DNA is investigated in heteroplasmic lines of D.melanogaster established by germ-plasm transplantation. Results suggest that both the nuclear and two types of mitochondrial genomes are involved in the selective transmission of mtDNA. Selection transmission of mtDNA in heteroplasmic lines depends on temperature in all cases of intra- and interspecific combinations.
(Tsujimoto et al., 1991)
A very rapid response in the induction of the α-regulatory subunit of the mitochondrial F1-ATPase complex is observed in 37oC heat shocked larvae.
(Luis et al., 1990)
Mitochondrial genes all have the prefix mt:. Data for individual mt genes will be found under the relevant records. This record includes only those data that cannot be conveniently assigned to a particular mt gene, and some general references. The complete D.melanogaster mtDNA sequence is 19,517-bp (Accession number U37541).
 
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Sequence Crossreferences
DDBJ / EMBL / GenBank
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hide Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym
MT:DNA
 
mtDNA
(Wagaman et al., 2004, Ballard et al., 2002, Cohen et al., 2003, Roberti et al., 2003, Mitrofanov et al., 2002, Rand et al., 2001, Maier et al., 2001, Ballard, 2000, Rand et al., 1998, Ballard et al., 1996, Kilpatrick and Rand, 1995, Lewis et al., 1994, Crandall and Templeton, 1993, Calleja et al., 1993, Matsuura et al., 1993, Tsujimoto et al., 1991, Nagata and Matsuura, 1991, Matsuura et al., 1991, Hale and Singh, 1991, Hale and Singh, 1991, Matsuura et al., 1990, Gonzalez et al., 1990, Tourmente et al., 1990, Wagaman et al., 2006, Park et al., 2006, Rand et al., 2007, Schloetterer and Nunes, 2007, Rand, 2011, Tsujino et al., 2002, Valenzuela, 2010, Rera et al., 2011, Nunes et al., 2010, Yui and Matsuura, 2006, Morel et al., 2008)
MtDNA
(Kann et al., 1998)
snRNA-d
 
Name Synonym
Mitochondrial DNA
 
small nuclear RNA d
 
Secondary FlyBase IDs
  • FBgn0003457
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hide Recent research papers ( 2 )
Rand, 2011, Genetica 139(5): 685--697
Population genetics of the cytoplasm and the units of selection on mitochondrial DNA in Drosophila melanogaster. [FBrf0213618]
Rera et al., 2011, Cell Metab. 14(5): 623--634
Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog. [FBrf0216555]
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