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Gene Dmel\TfIIA-S

General Information
Symbol	Dmel\TfIIA-S	Species	D. melanogaster
Name	Transcription-factor-IIA-S	Annotation symbol	CG5163
Feature type	protein_coding_gene	FlyBase ID	FBgn0013347
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	TFIIA, dTFIIA-S
Genomic Location
Chromosome (arm)	3R	Recombination map	3-
Cytogenetic map	95C8-95C8	Sequence location	3R:19,716,110..19,716,778 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Transcription-factor-IIA-S is referred to in FlyBase by the symbol Dmel\TfIIA-S (CG5163, FBgn0013347). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; neurogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; eye; trichogen cell; photoreceptor cell; photoreceptor cell R1; photoreceptor cell R6; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription factor IIA, beta-barrel; Transcription factor IIA, helical; Transcription initiation factor IIA, gamma subunit; Transcription initiation factor IIA, gamma subunit, C-terminal; Transcription initiation factor IIA, gamma subunit, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632370_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of TfIIA-S. Gene sequence location is 3R:19716110..19716778.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	Sequence features BKN22804 HFA16883 Controlled Vocabulary Terms positive regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 95C8-95C8   Limits computationally determined from genome sequence between P{PZ}l(3)0468404684 and P{PZ}Atg600096
Experimentally Determined Cytological Location
Cytogenetic map Notes References 95C6-95C8     (Zeidler, 1994.12.6)
Experimentally Determined Recombination Data
Location	3- (Zeidler, 1994.12.6)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\TfIIA-S for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) TfIIA-S-RA FBtr0084526  NM_079743   613   106
Additional Transcript Data & Comments
Reported size (kB)	0.6 (longest cDNA) (Yokomori et al., 1994)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein TfIIA-S-PA   FBpp0083912   12.2   106   8.70     NP_524467   AAF56199
Additional Polypeptide Data & Comments
Reported size (kDa)	106 (aa); 12 (kD predicted) (Yokomori et al., 1994) 12.5 (kD predicted) (Bernstein et al., 1994)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Transcription initiation factor IIA, gamma subunit, C-terminal (IPR015871) Transcription initiation factor IIA, gamma subunit, N-terminal (IPR015872) Transcription initiation factor IIA, gamma subunit (IPR003194) Transcription factor IIA, helical (IPR009083) Transcription factor IIA, beta-barrel (IPR009088)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695560   AA951021   AE014297 AAF56199   AI063405   AY113478 AAM29483   BI357748   BI632002   BP544464   BP544465   BP544763   BP544764   BP546851   BP547251   BP547738   BP547931   BP547973   BP548003   BP548104   BP548183   BP548543   BP550352   BP550353   BP550457   BP551345   BP551346   BP552195   BP552392   BP553678   BP553679   BP553688   BP553689   BP553869   BP553870   BP554771   BP554772   BP555217   BP555218   BP556146   BP556147   BP556711   BP556712   BP557463   BP557464   BP558212   BP558213   BP559029   BP559341   BP559430   BP559589   BP559590   BP560360   BT044069   CO274046   CO306660   CO322110   CO337737   EC198821   EC200494   EC214395   EC232563   EV585109   GH758393   GH758740   GH770677   GH771472   GH771551   GH773870   GH774556   GH780465   GH780810   GH787968   GH790436   GH794341   GH795590   GH798437   GH799499   GH803540   GH804043   GH806088   GH810594   GH814835   GH818148   GH826571   GH826931   GH829009   GH835129   GH836372   GH838833   GH841016   GH843542   GH845197   GH846399   GH851037   GH854623   GH855287   GH856494   GH861232   GH870800   GH871623   GH872102   GH881489   GH882560   GH883571   GH886102   GH887930   GH888017   GH890055   GH890905   GH893134   GH896844   GH897249   GH898404   GH903726   GH909845   GH910495   GH917238   GH919058   GH920307   GH922159   GH922169   GH924059   GH934764   GH938448   X83271 CAA58244
UniProtKB/Swiss-Prot	P52656
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
	TfIIA-S protein is present in embryonic nuclear extracts. (Bernstein et al., 1994)
Marker for
Subcellular Localization
CV Term	nucleus (Bernstein et al., 1994)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0013347    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0013347 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0013347 expression level Developmental Stage   Expression Level embryo 00-02hr    11234 embryo 02-04hr    21256 embryo 04-06hr    28038 embryo 06-08hr    22209 embryo 08-10hr    19557 embryo 10-12hr    17250 embryo 12-14hr    11715 embryo 14-16hr    10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (11234) embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  (19557) embryo 10-12hr  (17250) embryo 12-14hr  (11715) embryo 14-16hr  (10059) embryo 16-18hr  (8945) embryo 18-20hr  (7392) embryo 20-22hr  (6228) embryo 22-24hr  (6442) larva L1  (4681) larva L2  (3636) larva L3 12hr old  (3446) larva L3 puffstage 1-2  (6158) larva L3 puffstage 3-6  (7357) larva L3 puffstage 7-9  (8717) white prepupae new  (7975) white prepupae 12hr  (7270) white prepupae 24hr  (8884) pupae 2d postWPP  (8034) pupae 3d postWPP  (5621) pupae 4d postWPP  (4945) adult male 01day  (4371) adult male 05day  (5026) adult male 30day  (5266) adult female 01day  (6365) adult female 05day  (6641) adult female 30day  (6890) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (11234) embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  (19557) embryo 10-12hr  (17250) embryo 12-14hr  (11715) embryo 14-16hr  (10059) embryo 16-18hr  (8945) embryo 18-20hr  (7392) embryo 20-22hr  (6228) embryo 22-24hr  (6442) larva L1  (4681) larva L2  (3636) larva L3 12hr old  (3446) larva L3 puffstage 1-2  (6158) larva L3 puffstage 3-6  (7357) larva L3 puffstage 7-9  (8717) white prepupae new  (7975) white prepupae 12hr  (7270) white prepupae 24hr  (8884) pupae 2d postWPP  (8034) pupae 3d postWPP  (5621) pupae 4d postWPP  (4945) adult male 01day  (4371) adult male 05day  (5026) adult male 30day  (5266) adult female 01day  (6365) adult female 05day  (6641) adult female 30day  (6890) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (11234) embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  (19557) embryo 10-12hr  (17250) embryo 12-14hr  (11715) embryo 14-16hr  10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11234 embryo 02-04hr    21256 embryo 04-06hr    28038 embryo 06-08hr    22209 embryo 08-10hr    19557 embryo 10-12hr    17250 embryo 12-14hr    11715 embryo 14-16hr    10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0013347 expression level Developmental Stage   Expression Level embryo 00-02hr    11234 embryo 02-04hr    21256 embryo 04-06hr    28038 embryo 06-08hr    22209 embryo 08-10hr    19557 embryo 10-12hr    17250 embryo 12-14hr    11715 embryo 14-16hr    10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (11234) embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  (19557) embryo 10-12hr  (17250) embryo 12-14hr  (11715) embryo 14-16hr  (10059) embryo 16-18hr  (8945) embryo 18-20hr  (7392) embryo 20-22hr  (6228) embryo 22-24hr  (6442) larva L1  (4681) larva L2  (3636) larva L3 12hr old  (3446) larva L3 puffstage 1-2  (6158) larva L3 puffstage 3-6  (7357) larva L3 puffstage 7-9  (8717) white prepupae new  (7975) white prepupae 12hr  (7270) white prepupae 24hr  (8884) pupae 2d postWPP  (8034) pupae 3d postWPP  (5621) pupae 4d postWPP  (4945) adult male 01day  (4371) adult male 05day  (5026) adult male 30day  (5266) adult female 01day  (6365) adult female 05day  (6641) adult female 30day  (6890) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (11234) embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  (19557) embryo 10-12hr  (17250) embryo 12-14hr  (11715) embryo 14-16hr  (10059) embryo 16-18hr  (8945) embryo 18-20hr  (7392) embryo 20-22hr  (6228) embryo 22-24hr  (6442) larva L1  (4681) larva L2  (3636) larva L3 12hr old  (3446) larva L3 puffstage 1-2  (6158) larva L3 puffstage 3-6  (7357) larva L3 puffstage 7-9  (8717) white prepupae new  (7975) white prepupae 12hr  (7270) white prepupae 24hr  (8884) pupae 2d postWPP  (8034) pupae 3d postWPP  (5621) pupae 4d postWPP  (4945) adult male 01day  (4371) adult male 05day  (5026) adult male 30day  (5266) adult female 01day  (6365) adult female 05day  (6641) adult female 30day  (6890) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  11234 embryo 02-04hr  (21256) embryo 04-06hr  (28038) embryo 06-08hr  (22209) embryo 08-10hr  19557 embryo 10-12hr  17250 embryo 12-14hr  11715 embryo 14-16hr  10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11234 embryo 02-04hr    21256 embryo 04-06hr    28038 embryo 06-08hr    22209 embryo 08-10hr    19557 embryo 10-12hr    17250 embryo 12-14hr    11715 embryo 14-16hr    10059 embryo 16-18hr    8945 embryo 18-20hr    7392 embryo 20-22hr    6228 embryo 22-24hr    6442 larva L1    4681 larva L2    3636 larva L3 12hr old    3446 larva L3 puffstage 1-2    6158 larva L3 puffstage 3-6    7357 larva L3 puffstage 7-9    8717 white prepupae new    7975 white prepupae 12hr    7270 white prepupae 24hr    8884 pupae 2d postWPP    8034 pupae 3d postWPP    5621 pupae 4d postWPP    4945 adult male 01day    4371 adult male 05day    5026 adult male 30day    5266 adult female 01day    6365 adult female 05day    6641 adult female 30day    6890 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0013347    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0013347 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, larval salivary gland, larval trachea, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, adult salivary gland, adult spermathecae, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0013347 expression level Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (768.025) Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland  (561.9) Larval Trachea  (629.5) Larval Carcass    273.925 Adult Head    342.4 Adult Eye  (772.875) Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary  518.3 Adult Testis    269.6 Adult Male Accessory Gland  (698.3) Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0013347 expression level Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland  561.9 Larval Trachea  629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye  772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary  518.3 Adult Testis    269.6 Adult Male Accessory Gland  698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    768.025 Larval Midgut    262.6 Larval Hindgut    308.9 Larval Malpighian Tubules    494.7 Larval Fat Body    445.2 Larval Salivary Gland    561.9 Larval Trachea    629.5 Larval Carcass    273.925 Adult Head    342.4 Adult Eye    772.875 Adult Brain    449.3 Adult Thoracic-Abdominal Ganglion    447 Adult Crop    399.8 Adult Midgut    381.1 Adult Hindgut    418.1 Adult Malpighian Tubules    181.9 Adult Fat Body    180.2 Adult Salivary Gland    411.7 Adult Heart    486.55 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    122.5 Adult Ovary    518.3 Adult Testis    269.6 Adult Male Accessory Gland    698.3 Adult Carcass    257.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    342.4   NA  Eye    772.875   NA  Brain    449.3   768.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    447   NA  Crop    399.8   262.6  Midgut    381.1   308.9  Hindgut    418.1   494.7  Malpighian Tubules    181.9   445.2  Fat Body    180.2   561.9  Salivary Gland    411.7   NA  Heart    486.55   629.5  Trachea    NA   NA  VirginFemale Spermatheca    135.3   NA  InseminatedFemale Spermatheca    122.5   NA  Ovary    518.3   NA  Testis    269.6   NA  Male Accessory Gland    698.3   273.925  Carcass    257.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_30
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013347 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5163-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for TfIIA-S Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 TfIIA-SGD4733 lethal | embryonic stage | recessive TfIIA-SE32 lethal | pharate adult stage | recessive TfIIA-SE73 semi-lethal, with Scer\GAL429BD TfIIA-SGS97 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 TfIIA-SGD4733 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 TfIIA-SGD4733 visible, with Scer\GAL429BD TfIIA-SGS97 visible, with Scer\GAL4c355 TfIIA-SGS97 visible, with Scer\GAL4pnr-MD237 TfIIA-SGD4733 wild-type TfIIA-S+t4 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage, with Scer\GAL41407 TfIIA-SGD4733 eye TfIIA-SE73 eye, with Scer\GAL429BD TfIIA-SGS97 eye, with Scer\GAL4c355 TfIIA-SGS97 ganglion mother cell | larval stage, with Scer\GAL41407 TfIIA-SGD4733 mesothoracic tergum, with Scer\GAL4pnr-MD237 TfIIA-SGD4733 photoreceptor cell TfIIA-SE73 photoreceptor cell R1 TfIIA-SE73 photoreceptor cell R6 TfIIA-SE73 photoreceptor cell R7 TfIIA-SE73 trichogen cell, with Scer\GAL4pnr-MD237 TfIIA-SGD4733
Classical Alleles ( 8 )
For All Classical Alleles Show
Allele of TfIIA-S Class Mutagen Stocks Known lesion TfIIA-SE32 amorphic allele - genetic evidence Delta2-3 1 Yes TfIIA-SE73 hypomorphic allele - genetic evidence Delta2-3 1 Yes TfIIA-SGS97 Delta2-3 1 Yes TfIIA-SE31 amorphic allele - genetic evidence Delta2-3 0 Yes TfIIA-SE62 amorphic allele - genetic evidence Delta2-3 0 Yes TfIIA-SE69 amorphic allele - genetic evidence Delta2-3 0 Yes TfIIA-SE89 amorphic allele - genetic evidence Delta2-3 0 Yes TfIIA-SEP3285 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of TfIIA-S Class Mutagen Stocks Known lesion TfIIA-SGD4733 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes TfIIA-SGL00359 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes TfIIA-S+t4 in vitro construct - genomic fragment 0 Yes TfIIA-Shs.PZ in vitro construct - regulatory fusion 0 Yes TfIIA-SKK102708 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)06624 (Zeidler et al., 1996, Haghayeghi et al., 2010) Df(3R)Exel9014 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4733} NA P{KK102708} NA P{TRiP.GL00359} NA heat-shock construct P{hsp70-dTFIIA-S} NA characterization construct P{dTFIIA-S} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}TfIIA-SEP3285 NA P{EPgy2}EY02323 NA P{GSV1}TfIIA-SGS97 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function
CV term Evidence References
contributes_to RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly inferred from physical interaction with TfIIA-L (Yokomori et al., 1994) TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly inferred from physical interaction with Tbp (Yokomori et al., 1994)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011) positive regulation of transcription from RNA polymerase II promoter inferred from direct assay (Yokomori et al., 1994)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Yokomori et al., 1994) transcription factor TFIIA complex inferred from direct assay (Yokomori et al., 1994)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
regulation of transcription from RNA polymerase II promoter non-traceable author statement (Swiss-Prot Project Members, 1996.10.1) transcription initiation from RNA polymerase II promoter inferred from sequence or structural similarity with human GTF2A2 AND inferred from sequence or structural similarity with Saccharomyces TOA2 (Aoyagi and Wassarman, 2000)
Cellular Component
CV term Evidence References
nucleus non-traceable author statement (Swiss-Prot Project Members, 1996.10.1) transcription factor TFIIA complex inferred from sequence or structural similarity with human GTF2A2 AND inferred from sequence or structural similarity with Saccharomyces TOA2 (Aoyagi and Wassarman, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions TfIIA-S allele Gene References TfIIA-SE73 Ras85D (Zeidler et al., 1996) rl (Zeidler et al., 1996) sev (Zeidler et al., 1996) svp (Zeidler et al., 1996) unspecified L (Singh et al., 2005) tor (Zeidler et al., 1996)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 67758 DroID - A comprehensive database of gene and protein interactions. • FBgn0013347 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42822
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18732 Dere\GG12397 Dgri\GH10565 Dmoj\GI23054 Dper\GL24263 Dpse\GA18701 Dsec\GM23533 Dsim\GD18345 Dvir\GJ24638 Dwil\GK11978 Dyak\GE23914
Curated drosophilid orthologs	Dpse\GA18701   Dvir\TfIIA-S
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002140-PA Aedes aegypti (mosquito) AGAP004370-PA Anopheles gambiae (mosquito) XP_623063.1 Apis mellifera (honey bee) XP_001943812.1 Acyrthosiphon pisum (pea aphid) At4g24440.1 Arabidopsis thaliana (wall cress) 9833 Batrachochytrium dendrobatidis (chytrid fungus) BGIBMGA005169-PA Bombyx mori (silk worm) ENSBTAP00000013602 Bos taurus (bovine) CAL0003642 Candida albicans (a form of yeast) CN23599 Caenorhabditis brenneri (small nematode) CBP31513 Caenorhabditis briggsae (nematode) CE26630 Caenorhabditis elegans (worm) ENSCAFP00000024508 Canis familiaris (dog) CAGL0I05434g Candida glabrata (haploid yeast) JA05797 Caenorhabditis japonica (nematode) cn07435 Cryptococcus neoformans (yeast-like fungus) CPIJ007398 Culex pipens (mosquito) ENSCPOP00000000730 Cavia porcellus (guinea pig) 186321 Chlamidomonas reinhardtii (green alga) RP04789 Caenorhabditis remanei (nematode) ENSCSAVP00000014862 Ciona savignyi (sedentary tunicate) 146781 Capitella spl (polychaete worm) DDB0216276 Dictyostelium discoideum (amoeba) DEHA2G02486g Debaryomyces Hansenii (yeast) 230366 Daphnia pulex (daphnia) ENSDARP00000070238 Danio rerio (zebra fish) ENSECAP00000009945 Equus caballus (horse) ENSGACP00000023257 Gymnopilus aculeatus (mushroom) ENSGALP00000006007 Gallus gallus (chicken) 73469 Hypsipyla robusta (cedar shoot borer) ENSP00000267869 Homo sapiens (human) ISCW010050-PA Ixodes scapularis (deer tick) KLLA0C12815g Kluyveromyces lactis (yeast) 238741 Lottia gigantea (owl limpet) ENSMODP00000014575 Monodelphis domestica (gray opossum) ENSMMUP00000024248 Macaca mulatta (rhesus monkey) ENSMUSP00000109238 Mus musculus (house mouse) 67237 Nematostella vectensis (starlet anemone) XP_001607333.1 Nasonia vitripennis (wasp) ENSOANP00000021725 Ornithorynchus anatinus (platypus) ENSORLP00000022993 Oryzias latipes (japanese killifish) LOC_Os05g01710.1 Oryza sativa (asian rice) 7618 Ostreococcus tauri (green alga) PHUM001853-PA Pediculus humanus (human body louse) PP01359 Pristionchus pacificus (nematode) 133519 Physcomitrella patens (moss) 178304 Physcomitrella patens (moss) ENSPPYP00000007396 Pongo pygmaeus (orangutan) 831453 Populus trichocarpa (black cottonwood) ENSPTRP00000012186 Pan troglodytes (chimpanzee) ENSRNOP00000014706 Rattus norvegicus (norway rat) 4766722 Sorghum bicolor (sorghum) YKL058W Saccharomyces cerevisiae (budding yeast) Smp_071830 Schistosoma mansoni (trematode parasite) SPCC553.11c Schizosaccharomyces pombe (fission yeast) XP_001195833.1 Strongylocentrotus purpuratus (purple sea urchin) 49735 Trichoplax adhaerens (metazoa) XP_970803.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005121 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000008785 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000047620 Xenopus tropicalis (frog) ENSXETP00000056546 Xenopus tropicalis (frog) YALI0F22136g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12750 LH16138 ISCW010050 FBgn0241062 FBgn0213989 FBgn0211715 FBgn0189874 FBgn0178399 JGI_V11_230366 FBgn0078701 FBgn0161853 FBgn0145781 FBgn0118046 FBgn0104685 FBgn0095749 CPIJ007398 BGIBMGA005169 ACYPI007048 GB17295 AGAP004370 AAEL002154 AAEL002140 PB20010 PHUM492470 GLEAN_09112
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	35800 y1 sc* v1; P{TRiP.GL00359}attP2 5436 w*; P{neoFRT}82B TfIIA-SE73/TM6B, Tb1 5437 w*; TfIIA-SE32/TM3, P{Thb8-lacZ}WD1, Sb1 Ser1
Kyoto	200041 y1 w67c23; P{GSV1}TfIIA-SGS97/TM3, Sb1 Ser1
VDRC	v12745 w1118; P{GD4733}v12745 v12746 w1118; P{GD4733}v12746/CyO
Genomic Clones ( 1 )
	BACR05C11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 107 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE44302
Other clones	FI01012
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03194 GM03032 LD31265 RH56668
Other clones	12070 31591 61574 120182 Dmel_dig_013742_0660_3359 EK112950 EK187238 EK251724 EN15207 FGC026A07 FGC027F07 FGH110G07 FGH115A05 FGH120B10 FGH122C01 FGH122F08 FGH123A03 FGH124A09 FGH124H06 FGH128H06 FGM206F09 FGM207C05 FGM212D02 FGM217D04 FGM218E05 FGM225F12 FGM225G05 FGM226G02 FGM231F06 FGM234B01 FGM301F08 FGM305B03 FGM309D11 FGM313F10 FGM318D11 FGM320D02 FGM320H09 FGM321G07 FGX001C11 RP003018300 RP003018411 RP003025575 RP003035702 RP003046397 RP003052887 RP003075137 RP003081125 RP003099863 RP003112800 RP003118135 RP003136841 RP003146929 RP003154363 RP003162583 RP003170017 RP003206581 RP003257025 RP003266642 RP003271952 RP003277824 RP003279289 RP003280689 RP003298125 RP003302654 RP003304149 RP003307410 RP003309117 RP003315715 RP003322565 RP003322661 RP003335434 RP003349358 RP003428692 RP003446326 RP003448434 RP003451726 RP003462070 RP003464888 RP003485691 RP003499105 RP003499742 RP003513405 RP003521973 RP003527072 RP003536017 RP003541840 RP003542128 RP003560555 RP003561860 RP003568040 RP003568199 RP003570393 RP003576712 RP003602495 RP003603690 RP003608994 RP003615514 RP003619821 RP003663129 RP003670184 RP003678754
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0013347 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42822
Antibody Information
	polyclonal (Bernstein et al., 1994)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: TfIIA-S CG5163 (Kodira, 1999.11)
Source for database merge of	Source for merge of: TfIIA-S BcDNA:RE44302 (FlyBase, 1996-)
Additional comments	Source for merge of TfIIA-S BcDNA:RE44302 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
	Expression is enriched in embryonic gonads. (Shigenobu et al., 2006) TfIIA-S is up-regulated and required during Ras-mediated photoreceptor determination. (Zeidler et al., 1996) 12.5kD small subunit of TFIIA is cloned and the properties of the recombinant protein are studied in vitro. The recombinant protein, in conjunction with human TFIIA, can support both promoter complex formation and transcriptional activated expression of TFIIA. (Bernstein et al., 1994) TfIIA-S has been isolated, molecularly cloned and expressed. Recombinant purified TfIIA-L and TfIIA-S can form a stable complex with Tbp on DNA, the recombinant protein can stimulate basal transcription and enhances transcriptional activation. (Yokomori et al., 1994) Mitotic recombination reveals TfIIA-S does not have a role in eye development. (Zeidler and Mlodzik, 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079743 RefSeq (Proteins) • NP_524467 DDBJ / EMBL / GenBank • AAF56199 AAM29483 AY113478 BI357748 CAA58244 X83271 Entrez Gene - A searchable database of RefSeq genes. • 42822 UniProtKB/Swiss-Prot • P52656
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Transcription initiation factor IIA, gamma subunit, C-terminal (IPR015871) Transcription initiation factor IIA, gamma subunit, N-terminal (IPR015872) Transcription initiation factor IIA, gamma subunit (IPR003194) Transcription factor IIA, helical (IPR009083) Transcription factor IIA, beta-barrel (IPR009088)
Linkouts
	BioGRID - A database of protein and genetic interactions • 67758 DroID - A comprehensive database of gene and protein interactions. • FBgn0013347 DRSC - Results from RNAi screens. • FBgn0013347 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013347 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5163-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0013347 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42822 InParanoid A subset of ortholog calls from InParanoid. • AAEL002140-PA Aedes aegypti (mosquito) AGAP004370-PA Anopheles gambiae (mosquito) XP_623063.1 Apis mellifera (honey bee) XP_001943812.1 Acyrthosiphon pisum (pea aphid) At4g24440.1 Arabidopsis thaliana (wall cress) 9833 Batrachochytrium dendrobatidis (chytrid fungus) BGIBMGA005169-PA Bombyx mori (silk worm) ENSBTAP00000013602 Bos taurus (bovine) CAL0003642 Candida albicans (a form of yeast) CN23599 Caenorhabditis brenneri (small nematode) CBP31513 Caenorhabditis briggsae (nematode) CE26630 Caenorhabditis elegans (worm) ENSCAFP00000024508 Canis familiaris (dog) CAGL0I05434g Candida glabrata (haploid yeast) JA05797 Caenorhabditis japonica (nematode) cn07435 Cryptococcus neoformans (yeast-like fungus) CPIJ007398 Culex pipens (mosquito) ENSCPOP00000000730 Cavia porcellus (guinea pig) 186321 Chlamidomonas reinhardtii (green alga) RP04789 Caenorhabditis remanei (nematode) ENSCSAVP00000014862 Ciona savignyi (sedentary tunicate) 146781 Capitella spl (polychaete worm) DDB0216276 Dictyostelium discoideum (amoeba) DEHA2G02486g Debaryomyces Hansenii (yeast) 230366 Daphnia pulex (daphnia) ENSDARP00000070238 Danio rerio (zebra fish) ENSECAP00000009945 Equus caballus (horse) ENSGACP00000023257 Gymnopilus aculeatus (mushroom) ENSGALP00000006007 Gallus gallus (chicken) 73469 Hypsipyla robusta (cedar shoot borer) ENSP00000267869 Homo sapiens (human) ISCW010050-PA Ixodes scapularis (deer tick) KLLA0C12815g Kluyveromyces lactis (yeast) 238741 Lottia gigantea (owl limpet) ENSMODP00000014575 Monodelphis domestica (gray opossum) ENSMMUP00000024248 Macaca mulatta (rhesus monkey) ENSMUSP00000109238 Mus musculus (house mouse) 67237 Nematostella vectensis (starlet anemone) XP_001607333.1 Nasonia vitripennis (wasp) ENSOANP00000021725 Ornithorynchus anatinus (platypus) ENSORLP00000022993 Oryzias latipes (japanese killifish) LOC_Os05g01710.1 Oryza sativa (asian rice) 7618 Ostreococcus tauri (green alga) PHUM001853-PA Pediculus humanus (human body louse) PP01359 Pristionchus pacificus (nematode) 133519 Physcomitrella patens (moss) 178304 Physcomitrella patens (moss) ENSPPYP00000007396 Pongo pygmaeus (orangutan) 831453 Populus trichocarpa (black cottonwood) ENSPTRP00000012186 Pan troglodytes (chimpanzee) ENSRNOP00000014706 Rattus norvegicus (norway rat) 4766722 Sorghum bicolor (sorghum) YKL058W Saccharomyces cerevisiae (budding yeast) Smp_071830 Schistosoma mansoni (trematode parasite) SPCC553.11c Schizosaccharomyces pombe (fission yeast) XP_001195833.1 Strongylocentrotus purpuratus (purple sea urchin) 49735 Trichoplax adhaerens (metazoa) XP_970803.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005121 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000008785 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000047620 Xenopus tropicalis (frog) ENSXETP00000056546 Xenopus tropicalis (frog) YALI0F22136g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42822 modMine - Data generated by the modENCODE project. • FBgn0013347 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12750 LH16138 ISCW010050 FBgn0241062 FBgn0213989 FBgn0211715 FBgn0189874 FBgn0178399 JGI_V11_230366 FBgn0078701 FBgn0161853 FBgn0145781 FBgn0118046 FBgn0104685 FBgn0095749 CPIJ007398 BGIBMGA005169 ACYPI007048 GB17295 AGAP004370 AAEL002154 AAEL002140 PB20010 PHUM492470 GLEAN_09112
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	BcDNA:RE44302   CG5163 (Aoyagi and Wassarman, 2000, Keleman et al., 2009.8.5, Ni et al., 2011.7.19) dTFIIA (Ryu et al., 1999) dTFIIA-S (Miller et al., 2000, Zeidler, 1994.12.6, Vivas et al., 1999, Zeidler and Mlodzik, 1997, Zeidler et al., 1996, Bernstein et al., 1994, Yokomori et al., 1994) F121 (Zeidler and Mlodzik, 1993, ) TFIIA (Arnosti, 2002, Gu et al., 2002, Mizuguchi et al., 2001, Farkas et al., 2000, Pham et al., 1999, Rabenstein et al., 1999, Schock et al., 1999, Sandaltzopoulos and Becker, 1998, Hansen et al., 1997, Sauer et al., 1995, Sauer et al., 1995, Goodrich and Tjian, 1994) TFIIA-S (Maixner et al., 1998, Shigenobu et al., 2006, Hsu et al., 2008, Santoso and Kadonaga, 2006) TfIIA-S (Shigenobu et al., 2006) tfiia-s (Wood et al., 2008) TF-IIAS (Haghayeghi et al., 2010)
Name Synonym	Transcription-factor-IIA-S
Secondary FlyBase IDs
	FBgn0010326 FBgn0010327 FBgn0063013
References ( 53 )
Generate a list of	All references relating to this gene ( 53 )
List References by type	Research paper  ( 27 ) Supplementary material  ( 4 ) Review  ( 4 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 5 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 )
Recent research papers ( 1 )
	Haghayeghi et al., 2010, Mech. Dev. 127(5-6): 301--307 Pellino enhances innate immunity in Drosophila. [FBrf0210800] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...