FB2025_02 , released April 17, 2025
Gene: Dmel\mtd
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General Information
Symbol
Dmel\mtd
Species
D. melanogaster
Name
mustard
Annotation Symbol
CG32464
Feature Type
protein_coding_gene
FlyBase ID
FBgn0013576
Gene Model Status
Current
Stock Availability
46 publicly available
Gene Summary
mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

l(3)82Fd, L82, anon- EST:Posey263

Key Links
Genomic Location
Cytogenetic map
82F8-82F10
Sequence location
Recombination map
3-47.5
RefSeq locus
NT_033777 REGION:5270116..5350443
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (7 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in activation of innate immune response
inferred from mutant phenotype
(Wang et al., 2012)
involved_in defense response to Gram-negative bacterium
inferred from mutant phenotype
(Wang et al., 2012)
involved_in positive regulation of stem cell proliferation
inferred from mutant phenotype
(Wang et al., 2013)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in response to oxidative stress
inferred from biological aspect of ancestor with PANTHER:PTN001156357
(GO Reference Genome Project, 2011-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Wang et al., 2012)
located_in nucleus
inferred from direct assay
(Wang et al., 2012)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
located_in mitochondrion
inferred from sequence or structural similarity with UniProtKB:Q8N573
(Gene Ontology Curators, 2002-)
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN001156357
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. [Date last reviewed: 2019-03-14]
Gene Model and Products
Number of Transcripts
23
Number of Unique Polypeptides
19

Please see the JBrowse view of Dmel\mtd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry A0A0B4K620)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Gene model reviewed during 5.39

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.46

Gene model reviewed during 5.55

Gene model reviewed during 6.08

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
mtd-RA
FBtr0078817
NM_170644
4719
210
mtd-RAA
FBtr0333695
NM_001275350
3789
871
mtd-RB
FBtr0078810
NM_143760
8072
1270
mtd-RC
FBtr0078815
NM_170643
2303
267
mtd-RF
FBtr0078813
NM_170641
3783
869
mtd-RG
FBtr0078818
NM_206429
4780
1033
mtd-RH
FBtr0078816
NM_169045
1675
192
mtd-RI
FBtr0078814
NM_170642
4838
213
mtd-RJ
FBtr0078811
NM_169038
5167
1270
mtd-RK
FBtr0078812
NM_170640
4502
1055
mtd-RM
FBtr0100197
NM_001031978
4083
1012
mtd-RN
FBtr0100199
NM_001031977
5214
1270
mtd-RO
FBtr0110932
NM_001043214
4332
1025
mtd-RP
FBtr0110933
NM_001043213
5373
1314
mtd-RQ
FBtr0273430
NM_001144534
2394
192
mtd-RR
FBtr0273431
NM_001144535
4175
789
mtd-RS
FBtr0273432
NM_001144536
4651
1106
mtd-RT
FBtr0273433
NM_001144537
5170
1106
mtd-RU
FBtr0273434
NM_169039
5169
1246
mtd-RV
FBtr0306694
NM_001259999
5689
1344
mtd-RW
FBtr0306695
NM_001260000
6314
1180
mtd-RX
FBtr0308580
NM_169047
5976
1127
mtd-RY
FBtr0308581
NM_001260001
4905
1158
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
mtd-PA
FBpp0078460
23.7
210
4.92
Q7KTR7
NP_730915
AAF52048
mtd-PAA
FBpp0305848
94.7
871
4.83
A0A0B4KF88
NP_001262279
AGB95662
mtd-PB
FBpp0078453
138.8
1270
5.36
Q9VNA1
NP_652017
AAF52045
mtd-PC
FBpp0078458
30.1
267
5.77
Q7KTR8
NP_730914
AAF52047
mtd-PF
FBpp0078456
94.4
869
4.81
Q8IPN8
NP_730912
AAN13272
mtd-PG
FBpp0089229
112.5
1033
5.06
Q8MSQ5
NP_996151
AAN13276
mtd-PH
FBpp0078459
21.7
192
4.87
Q8IPN6
NP_730916
AAN13274
mtd-PI
FBpp0078457
24.1
213
6.63
Q8IPN7
NP_730913
AAN13273
mtd-PJ
FBpp0078454
138.8
1270
5.36
Q9VNA1
NP_730909
AAN13269
mtd-PK
FBpp0078455
114.7
1055
5.11
Q8IPN9
NP_730911
AAN13271
mtd-PM
FBpp0099567
110.2
1012
4.93
Q4ABH3
NP_001027149
AAZ52516
mtd-PN
FBpp0099569
138.8
1270
5.36
Q9VNA1
NP_001027148
AAZ52515
mtd-PO
FBpp0110232
111.5
1025
4.99
Q7KNC5
NP_001036679
ABI31140
mtd-PP
FBpp0110233
143.2
1314
5.31
Q0KIB9
NP_001036678
ABI31139
mtd-PQ
FBpp0271938
21.7
192
4.87
Q8IPN6
NP_001138006
ACL83465
mtd-PR
FBpp0271939
85.8
789
4.72
B7Z0T6
NP_001138007
ACL83466
mtd-PS
FBpp0271940
120.1
1106
5.64
B7Z0T3
NP_001138008
ACL83467
mtd-PT
FBpp0271941
120.1
1106
5.64
B7Z0T3
NP_001138009
ACL83468
mtd-PU
FBpp0271942
136.1
1246
5.22
A4V2F2
NP_730910
AAN13270
mtd-PV
FBpp0297633
146.4
1344
5.45
A0A0B4K620
NP_001246928
AFH06247
mtd-PW
FBpp0297634
127.7
1180
5.72
A0A0B4K6S8
NP_001246929
AFH06248
mtd-PX
FBpp0300804
121.9
1127
5.06
Q9VNA2
NP_730918
AAF52044
mtd-PY
FBpp0300805
126.8
1158
5.24
A0A0B4K699
NP_001246930
AFH06249
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1270 aa isoforms: mtd-PB, mtd-PJ, mtd-PN
192 aa isoforms: mtd-PH, mtd-PQ
1106 aa isoforms: mtd-PS, mtd-PT
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mtd using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.06

Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytoplasm
inferred from direct assay
(Wang et al., 2012)
located_in nucleus
inferred from direct assay
(Wang et al., 2012)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\mtd in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 35 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 15 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of mtd
Transgenic constructs containing regulatory region of mtd
Aberrations (Deficiencies and Duplications) ( 4 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal | recessive
lethal - all die before end of P-stage
lethal - all die before end of P-stage, with Scer\GAL4Act5C.PI
lethal - all die before end of P-stage (with Df(3R)3-4)
lethal - all die before end of P-stage (with mtd1)
lethal - all die before end of P-stage (with mtdMI02920-TG4.0)
lethal - all die during P-stage, with Scer\GAL4Mef2.PR
partially lethal - majority die
partially lethal - majority die (with Df(3R)3-4)
viable
viable, with Scer\GAL4Act5C.PI
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
viable (with Df(3R)3-4)
viable (with mtdMI02920)
viable (with mtdMI02920-TG4.0)
Sterility
Allele
fertile
Other Phenotypes
Allele
abnormal eye color | recessive
abnormal heat stress response | third instar larval stage, with Scer\GAL4ppk.1.9
abnormal locomotor behavior | adult stage
abnormal locomotor behavior | adult stage (with Df(3R)3-4)
abnormal neuroanatomy | adult stage, with Scer\GAL4elav.PLu
abnormal oxidative stress response
abnormal oxidative stress response, with Scer\GAL4da.G32
abnormal oxidative stress response (with mtde00435)
abnormal oxidative stress response (with mtdKG02600)
abnormal stress response
abnormal stress response, with Scer\GAL4da.G32
abnormal stress response, with Scer\GAL4NP0001
bang sensitive
bang sensitive (with Df(3R)3-4)
decreased occurrence of cell division | adult stage
decreased occurrence of cell division | adult stage, with Scer\GAL4NP5130
decreased occurrence of cell division | adult stage (with mtde00435)
decreased occurrence of cell division | adult stage (with mtdKG02600)
increased occurrence of cell division | adult stage
majority die during pharate adult stage
short lived
short lived, with Scer\GAL4elav.PLu
short lived, with Scer\GAL4nSyb.PP
short lived (with Df(3R)3-4)
some die during immature adult stage | recessive
some die during pharate adult stage (with Df(3R)3-4)
some die during P-stage, with Scer\GAL4Act5C.PI
some die during pupal stage
some die during pupal stage (with Df(3R)3-4)
visible, with Scer\GAL4pnr-MD237
visible | adult stage
visible | adult stage (with Df(3R)3-4)
wild-type
Phenotype manifest in
Allele
adult brain, with Scer\GAL4elav.PLu
autophagosome | adult stage, with Scer\GAL4elav.PLu
intestinal stem cell
intestinal stem cell, with Scer\GAL4NP5130
intestinal stem cell (with mtde00435)
intestinal stem cell (with mtdKG02600)
lysosome | adult stage, with Scer\GAL4elav.PLu
lysosome | adult stage | progressive, with Scer\GAL4elav.PLu
mesonotum, with Scer\GAL4pnr-MD237
photoreceptor cell R7, with Scer\GAL4elav.PLu
pigment cell
trichogen cell, with Scer\GAL4pnr-MD237
wing
wing (with Df(3R)3-4)
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (16)
Hsap\OXR1
11 of 14
Yes
Yes
 
1  
Hsap\NCOA7
10 of 14
No
Yes
 
2  
Hsap\TLDC2
6 of 14
No
Yes
2  
Hsap\EVI5
1 of 14
No
No
1  
Hsap\EVI5L
1 of 14
No
No
Hsap\MEAK7
1 of 14
No
No
Hsap\SGSM3
1 of 14
No
No
Hsap\TBC1D1
1 of 14
No
No
1  
Hsap\TBC1D2B
1 of 14
No
No
Hsap\TBC1D2
1 of 14
No
No
Hsap\TBC1D9B
1 of 14
No
No
Hsap\TBC1D9
1 of 14
No
No
1  
Hsap\TBC1D10A
1 of 14
No
No
Hsap\TBC1D10B
1 of 14
No
No
Hsap\TBC1D10C
1 of 14
No
No
Hsap\TBC1D24
1 of 14
No
No
5  
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (14)
Rnor\Ncoa7
10 of 14
Yes
Yes
Rnor\Oxr1
10 of 14
Yes
Yes
Rnor\Tldc2
7 of 14
No
Yes
Rnor\Evi5l
1 of 14
No
No
Rnor\Evi5
1 of 14
No
No
Rnor\Meak7
1 of 14
No
No
Rnor\Sgsm3
1 of 14
No
No
Rnor\Tbc1d1
1 of 14
No
No
Rnor\Tbc1d2
1 of 14
No
No
Rnor\Tbc1d4
1 of 14
No
No
Rnor\Tbc1d9
1 of 14
No
No
Rnor\Tbc1d10a
1 of 14
No
No
Rnor\Tbc1d10b
1 of 14
No
No
Rnor\Tbc1d24
1 of 14
No
No
Mus musculus (laboratory mouse) (14)
Mmus\Oxr1
11 of 14
Yes
Yes
Mmus\Ncoa7
10 of 14
No
Yes
Mmus\Tldc2
5 of 14
No
Yes
Mmus\Tbc1d24
2 of 14
No
No
Mmus\Evi5l
1 of 14
No
No
Mmus\Meak7
1 of 14
No
No
Mmus\Sgsm3
1 of 14
No
No
Mmus\Tbc1d1
1 of 14
No
No
Mmus\Tbc1d2b
1 of 14
No
No
Mmus\Tbc1d2
1 of 14
No
No
Mmus\Tbc1d4
1 of 14
No
No
Mmus\Tbc1d9
1 of 14
No
No
Mmus\Tbc1d10a
1 of 14
No
No
Mmus\Tbc1d10b
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (11)
Xtro\oxr1
9 of 13
Yes
Yes
Xtro\ncoa7
7 of 13
No
Yes
Xtro\tldc2
4 of 13
No
Yes
Xtro\evi5
1 of 13
No
No
Xtro\fscn2
1 of 13
No
No
Xtro\kdm3a
1 of 13
No
No
Xtro\meak7
1 of 13
No
No
Xtro\ndufaf4
1 of 13
No
No
Xtro\sgsm3
1 of 13
No
No
Xtro\tbc1d1
1 of 13
No
No
Xtro\tbc1d24.1
1 of 13
No
No
Danio rerio (Zebrafish) (14)
Drer\oxr1b
11 of 14
Yes
Yes
Drer\LOC792958
6 of 14
No
Yes
Drer\si:ch211-15d5.11
5 of 14
No
Yes
Drer\LOC569262
4 of 14
No
Yes
Drer\tbc1d24
2 of 14
No
No
Drer\evi5l
1 of 14
No
No
Drer\grtp1b
1 of 14
No
No
Drer\LOC101885192
1 of 14
No
Yes
Drer\meak7
1 of 14
No
No
Drer\oxr1a
1 of 14
No
Yes
Drer\sgsm3
1 of 14
No
No
Drer\tbc1d2b
1 of 14
No
No
Drer\tbc1d10b
1 of 14
No
No
Drer\tbc1d14
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (5)
Cele\lmd-3
13 of 14
Yes
Yes
Cele\C31H2.14
1 of 14
No
Yes
Cele\eak-7
1 of 14
No
No
Cele\tbc-6
1 of 14
No
No
Cele\tbc-7
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (7)
Agam\AgaP_AGAP001751
11 of 12
Yes
Yes
Agam\AgaP_AGAP010235
2 of 12
No
No
Agam\AgaP_AGAP001953
1 of 12
No
No
Agam\AgaP_AGAP002120
1 of 12
No
No
Agam\AgaP_AGAP007332
1 of 12
No
No
Agam\AgaP_AGAP007765
1 of 12
No
No
Agam\AgaP_AGAP011079
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (8)
Atha\AT2G05590
8 of 13
Yes
Yes
Atha\AT4G39870
8 of 13
Yes
Yes
Atha\AT3G02460
1 of 13
No
No
Atha\AT3G07890
1 of 13
No
No
Atha\AT4G34070
1 of 13
No
No
Atha\AT5G06260
1 of 13
No
No
Atha\AT5G39590
1 of 13
No
No
Atha\PAM1
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\OXR1
8 of 13
Yes
Yes
Scer\MDR1
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (4)
Spom\mug63
6 of 12
Yes
Yes
Spom\gyp3
1 of 12
No
No
Spom\SPAC4G8.04
1 of 12
No
No
Spom\SPBC215.01
1 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:mtd. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (6)
sky
4 of 13
CG5149
3 of 13
CG4658
2 of 13
CG5916
1 of 13
CG12241
1 of 13
wkd
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 2 )
Potential Models Based on Orthology ( 1 )
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
mtd4
ameliorates  autosomal recessive intellectual developmental disorder
modeled by Nab2EP3716
(Rounds et al., 2022)
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
OXR1; oxidation resistance 1
11 of 14
605609
 
NCOA7; nuclear receptor coactivator 7
10 of 14
609752
       
      TLDC2; TBC/LysM-associated domain containing 2
      6 of 14
           
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Dmel gene
          Ortholog showing functional complementation
          Supporting References
          mtd
          Hsap\NCOA7
          (Wang et al., 2019)
          mtd
          Hsap\OXR1
          (Wang et al., 2019)
          Interactions
          Summary of Physical Interactions
          Summary of Genetic Interactions
          Interaction Browsers
          View in FlyBase Interactions Browser   View in MIST tool (external link)
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Nab2
          suppressible
          mtd
          (Rounds et al., 2022)
          Rel
          suppressible
          mtd
          (Wang et al., 2012)
          Rel
          enhanceable
          mtd
          (Wang et al., 2012)
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          FlyBase
          External Links
          External Data
          Linkouts
          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
          Class of Gene
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          3R
          Recombination map
          3-47.5
          Cytogenetic map
          82F8-82F10
          Sequence location
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          82F8-82F10
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          82F-82F
          (Stowers, 1999.2.3)
          Experimentally Determined Recombination Data
          Location

          3-47.5

          (FlyBase, 2016)

          3-44.1

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (46)
          Genomic Clones (53)
          cDNA Clones (174)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments

              The 82F puff does not puff in l(3)82Fd4 flies suggesting that l(3)82Fd is the puff gene itself.

              (Carpenter, 1999)

              The broad developmental expression pattern of l(3)82Fd suggests it is controlled by both ecdysone-dependent and ecdysone-independent regulatory mechanisms.

              (Stowers et al., 1999)
              Relationship to Other Genes
              Source for database merge of

              Source for merge of: l(3)82Fd CG10199

              (Bayraktaroglu, 2000.4.12)

              Source for merge of: l(3)82Fd anon- EST:Posey263

              (FlyBase Genome Annotators, 2005)

              Source for merge of: l(3)82Fd CG10196

              (FlyBase, 1996-)
              Additional comments

              Annotations CG10196, CG10199 merged as CG32464 in release 3 of the genome annotation.

              (FlyBase Genome Annotators, 2002-2003)

              Source for merge of l(3)82Fd CG10196 was a shared cDNA ( date:010720 ).

              (FlyBase, 1996-)
              Nomenclature History
              Source for database identify of

              Source for identity of: mtd l(3)82Fd

              (Wang et al., 2012)
              Nomenclature comments
              Etymology
              Synonyms and Secondary IDs (12)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 169 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              References (92)