mtlrRNA, 16S, lrRNA, 16SrRNA, 16S rRNA
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mt:lrRNA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mt:lrRNA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New annotation (CR34094) in release 4.3 of the genome annotation.
Steady state levels of mt:lrRNA decrease as adult Drosophila age, and this change correlates with the shape of the life span curve.
Maternal 16S rRNA localises to the pole region of the embryo.
The mitochondrial large ribosomal RNA gene maps to the mitochondrial DNA, between mt:srRNA and mt:ND1. It has previously been proposed that extra-mitochondrial mtlr-RNA is a component of the functional polar plasm: it induces pole cell formation in UV irradiated embryos (FBrf0049573). mtlr-RNA is enriched in germ plasm and is tightly associated with polar granules. Mutations in seven posterior group genes affects location of extra-mitochondrial mtlr, but alleles of nos have no effect (Ding, Whittaker and Lipschitz, unpublished data), suggesting that mtlr-RNA, like nos RNA, depends on the function of posterior group genes for its localization in the polar plasm.
During oogenesis RNA from mt:srRNA, mt:lrRNA, mt:ND2, mt:CoI, mt:CoII, mt:CoIII, mt:ND4, mt:ND5 and mt:Cyt-b shows fluctuations in RNA density after stage 9 in follicle and nurse cells.There is a correlation between the mtRNA level and the cell volume and/or the nuclear DNA content suggesting a global extra-mitochondrial, transcriptional control mechanism.